Pharmaceutical Standards
Pharmaceutical standards are a comprehensive set of reference materials essential for ensuring the safety, efficacy, and quality of pharmaceutical products. This category includes standards for active pharmaceutical ingredients (APIs), which are the core components responsible for therapeutic effects. Additionally, it covers compounds and metabolites relevant to both the pharmaceutical and veterinary industries, providing benchmarks for the accurate measurement and analysis of these substances. Nitrosamine control standards are crucial for detecting and mitigating potentially harmful nitrosamines in drug formulations. Toxicology standards help assess the safety and potential adverse effects of pharmaceutical compounds. Furthermore, enzyme activators and inhibitors standards are vital for research and development, enabling precise studies of biochemical pathways and drug mechanisms. These pharmaceutical standards are indispensable tools for regulatory compliance, quality control, and research, ensuring that pharmaceutical products meet stringent safety and effectiveness criteria.
Subcategories of "Pharmaceutical Standards"
- APIs for research and impurities(273,766 products)
- Enzyme Activators and Inhibitors(2,827 products)
- Nitrosamines(2,605 products)
- Pharmaceutical and Veterinary Compounds and Metabolites(2,608 products)
- Toxicology(13,652 products)
Found 7836 products of "Pharmaceutical Standards"
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Zolpidem Phenyl-4-carboxylic Acid
CAS:<p>Applications A major metabolite of Zolpidem.<br>References Crestani, F., et al.: Br. J. Pharmacol., 131, 1251 (2000), Li, Q., et al.: Bioorg. Med. Chem. Lett., 12, 465 (2002), Goulle, J., et al.: Ther. Drug Monit., 26, 206 (2004), Ohkanda, J., et al.: J. Med. Chem., 47, 432 (2004), Blackaby, W., et al.: Bioorg. Med. Chem. Lett., 16, 1175 (2006),<br></p>Formula:C19H19N3O3Color and Shape:Off-White To Light BeigeMolecular weight:337.37Piretanide
CAS:<p>Applications High-ceiling loop diuretic; structurally related to Bumetanide (B689550). Diuretic.<br>References Merkel, W., et al.: Eur. J. Med. Chem., 11, 399 (1976), Pozet, N., et al.: Br. J. Clin. Pharmacol., 9, 577 (1980), Clissold, S.P., et al.: Drugs, 29, 489 (1985),<br></p>Formula:C17H18N2O5SColor and Shape:Light Yellow SolidMolecular weight:362.40N1,N12-Diacetylspermine Dihydrochloride
CAS:<p>Stability Hygrscopic<br>Applications N1,N12-Diacetylspermine Dihydrochloride is a diacetylated derivative of Spermine (S680510) and is recognized as a novel tumor marker in patients with breast and colorectal cancers.<br>References Kato, M., et al.: Anticancer Res., 34, 3053 (2014); Umemori, Y., et al.: Clin. Chim. Acta, 411, 1894 (2010); Kawakita, M., et al.: J. Biochem., 139, 315 (2006); Hiramatsu, K., et al.: Clin. Cancer Res., 11, 2986 (2005)<br></p>Formula:C14H32Cl2N4O2Color and Shape:NeatMolecular weight:359.34Telocinobufogenin
CAS:Controlled Product<p>Applications Telocinobufagin is isolated as a major component from skin secretion of the toad Bufo rubescens. Telocinobufogenin is a novel antibiotic cardiotonic.<br>References Akizawa, T., et al.: Chem. Pharm. Bull., 42, 754 (1994); Hancock, R., et al.: Antimicrob. Agents Chemother., 43, 1317 (1999); Jing, Y., et al.: J. Cancer Res., 85, 645 (1994); Kamano, Y., et al.: J. Med. Chem., 45, 5440 (2002); Schoner, W., et al.: Eur. J. Biochem., 269, 2440 (2002); Cunha Filho, G., et al.: Toxicon, 45, 777 (2005)<br></p>Formula:C24H34O5Color and Shape:NeatMolecular weight:402.52(-)-Biotin Sulfoxide
CAS:<p>Applications (-)-Biotin Sulfoxide, is a metabolite of Biotin (B389040), which is a growth factor present in minute amounts in every living cell, and plays an indispensable role in numerous naturally occurring carboxylation reactions.<br>References du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992),<br></p>Formula:C10H16N2O4SColor and Shape:White To Off-WhiteMolecular weight:260.315’-Tosyl Adenosine
CAS:Controlled Product<p>Applications 5’-Tosyl Adenosine (cas# 5135-30-8) is a compound useful in organic synthesis.<br></p>Formula:C17H19N5O6SColor and Shape:NeatMolecular weight:421.4317-Desacetyl Rocuronium Bromide
CAS:<p>Impurity Rocuronium EP Impurity C<br>Applications 17-Desacetyl Rocuronium Bromide (Rocuronium EP Impurity C) is a metabolite of Rocuronium (R639500), in human plasma.<br>References Kleef, U., et al.: J. Chromatogr., 621, 65 (1993), Proost, J., et al.: Br. J. Anaesth., 85, 717 (2000),<br></p>Formula:C30H51N2O3·BrColor and Shape:NeatMolecular weight:567.64(+)-(S)-Dihydrokavain
CAS:Controlled Product<p>Applications (+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.<br>References Warburton, E., et al.: Eur. J. Mass Spectrom., 12, 223(2006); Wang, J., et al.: J. Food Sci. Technol., 52, 1164 (2015)<br></p>Formula:C14H16O3Color and Shape:NeatMolecular weight:232.286β-Hydroxy-3α,5α-cycloandrostan-17-one
CAS:Controlled Product<p>Applications 6β-Hydroxy-3α,5α-cycloandrostan-17-one is a degredation product of Dehydroepiandrosterone Sodium Sulfate (S673250), an active agent in the preparation of a pharmaceutical for the treatment of asthma or other respiratory diseases.<br>References Ishihara, T., et al.: Drug. Develop. Indust. Pharmacy., 5, 263 (1979); Sollman, P.B., et al.: J. Org. Chem., 28, 3559 (1963); Van Renterghem, P., et al.: Steroids., 75, 1047 (2010);<br></p>Formula:C19H28O2Color and Shape:NeatMolecular weight:288.42Carvedilol Bis-carbazole
CAS:Controlled Product<p>Impurity Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B<br>Applications Carvedilol Bis-carbazole (Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B) is an impurity from the process of Carvedilol (C184625).<br></p>Formula:C39H39N3O6Color and Shape:Off-White To Light BeigeMolecular weight:645.74Betamethasone-∆17,20 21-Aldehyde(Mixture of Isomers)
CAS:Controlled Product<p>Applications A degradation and metabolic intermediate of Betamethasone (B3270000).<br></p>Formula:C22H27FO4Color and Shape:NeatMolecular weight:374.45Glutaurine Sodium Salt
CAS:<p>Applications Glutaurine Sodium Salt is the salt of Glutaurine (G597350) which has been observed to display antiepileptic effects with anti-amnesia properties. Mimics anxiolytic drug Diazepam (D416855).<br>References Bittner, S. et al.: Amino Acids., 28, 343 (2005); Uemura, S. et al.: Brain. res., 594, 347 (1992);<br></p>Formula:C7H14N2O6S•x(Na)Color and Shape:NeatMolecular weight:254.26229917β-Dihydro Equilin 3-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formula:C18H21O5S·NaColor and Shape:NeatMolecular weight:372.41Methionine-methyl-d3
CAS:Controlled Product<p>Applications Methionine-methyl-d3 is the labeled Methionine-methyl, a useful building block.<br></p>Formula:C5D3H8NO2SColor and Shape:NeatMolecular weight:152.23α-Propyl-α-(1-demethylethyl)-Verapamil Hydrochloride
CAS:Controlled Product<p>Applications α-Propyl-α-(1-demethylethyl)-Verapamil is an impurity of Verapamil (V125000, HCl salt) which is a calcium channel blocker.<br>References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)<br></p>Formula:C27H38N2O4·ClHColor and Shape:NeatMolecular weight:491.06Pipamazine
CAS:<p>Applications Pipamazine is a drug od the phenothiazine class which used to be used as an antiemetic.<br>References Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 22, 154 (1964); Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 21, 436 (1963);<br></p>Formula:C21H24ClN3OSColor and Shape:NeatMolecular weight:401.95MTIC
CAS:<p>Applications A metabolite of Temozolomide, an antineoplastic.<br></p>Formula:C5H8N6OColor and Shape:Off-WhiteMolecular weight:168.164-(4-Oxobutyl)benzoic Acid Methyl Ester
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 4-(4-Oxobutyl)benzoic Acid Methyl Ester is used as a reagent in the preparation of Pemetrexed (P219500) and furoxanoxyalkyl esters of Pemetrexed as antifolates and nitric oxide donors for use as anticancer agents.<br>References Zhao, D., et al.: Zhongguo Yaowu Huaxue Zazhi, 18, 445 (2008); Yi, B., et al.: Zhongguo Yiyao Gongye Zazhi, 37, 798 (2006); Min, T., et al.: Med. Chem. Res., 18, 495 (2009)<br></p>Formula:C12H14O3Color and Shape:NeatMolecular weight:206.24(-)-2-Methyl Isoborneol-d3
CAS:Controlled Product<p>Applications Isotope labelled (-)-2-Methylisoborneol (M314000), which is a derivative of Camphor (1) (C165805). (-)-2-Methylisoborneol is a flavor component of Robusta coffee responsible for the off-flavour aroma (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Money T. Nat Prod Rep. 1985 Jun;2(3):253-89.2. Blank I et al.: J Agric Food Chem. 2002 Jul 31;50(16):4653-6.<br></p>Formula:C112H3H17OColor and Shape:NeatMolecular weight:171.29
