Pharmaceutical Standards
Pharmaceutical standards are a comprehensive set of reference materials essential for ensuring the safety, efficacy, and quality of pharmaceutical products. This category includes standards for active pharmaceutical ingredients (APIs), which are the core components responsible for therapeutic effects. Additionally, it covers compounds and metabolites relevant to both the pharmaceutical and veterinary industries, providing benchmarks for the accurate measurement and analysis of these substances. Nitrosamine control standards are crucial for detecting and mitigating potentially harmful nitrosamines in drug formulations. Toxicology standards help assess the safety and potential adverse effects of pharmaceutical compounds. Furthermore, enzyme activators and inhibitors standards are vital for research and development, enabling precise studies of biochemical pathways and drug mechanisms. These pharmaceutical standards are indispensable tools for regulatory compliance, quality control, and research, ensuring that pharmaceutical products meet stringent safety and effectiveness criteria.
Subcategories of "Pharmaceutical Standards"
- APIs for research and impurities(273,766 products)
- Enzyme Activators and Inhibitors(2,827 products)
- Nitrosamines(2,605 products)
- Pharmaceutical and Veterinary Compounds and Metabolites(2,608 products)
- Toxicology(13,652 products)
Found 7836 products of "Pharmaceutical Standards"
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1,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid-d51
CAS:Controlled Product<p>Applications Isotope labelled 1,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid is a widely used and often incorporated in plasticizer for PVC for a higher molecular weight.<br>References Jones, C., et al.: Int. J. Artificial. Organs., 12, 466 (1989); Khang, G., et al.: Bio-Med. Mater. Engineer., 12, 135 (2002);<br></p>Formula:C33D51H3O6Color and Shape:NeatMolecular weight:598.092(4-Bromophenyl)urea
CAS:<p>Applications (4-Bromophenyl)urea (cas# 1967-25-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C7H7N2OBrColor and Shape:Off-White To PurpleMolecular weight:215.05Boc-L-aspartic Acid β-Methyl Ester
CAS:Controlled Product<p>Applications Boc-L-aspartic Acid β-Methyl Ester is used to prepare isoxazoline glycoprotein IIb/IIIa antagonists. It is also used to synthesize glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.<br>References Xue, C., et al.: J. Med. Chem., 40, 2064 (1997); Kirkland, T., et al.: Bioorg. Med. Chem., 16, 4963 (2008)<br></p>Formula:C10H17NO6Color and Shape:NeatMolecular weight:247.2458-Bromo-2’-deoxyguanosine
CAS:Controlled Product<p>Applications 8-Bromo-2’-deoxyguanosine (cas# 13389-03-2) is a compound useful in organic synthesis.<br>References Chatgilialoglu, C., et al.: Chem. Res. Toxicol., 20, 1820 (2007),<br></p>Formula:C10H12BrN5O4Color and Shape:NeatMolecular weight:346.142,2',3,4,4',5'-Hexabromodiphenyl Ether
CAS:Controlled Product<p>Applications 2,2',3,4,4',5'-Hexabromodiphenyl Ether is a polybrominated diphenyl ether (PBDE) used as a flame retardant.<br>References Rayne, S., et al.: Environ. Int., 32, 575 (2006); Jakobsson, K., et al.: Chemosphere, 46, 709 (2002)<br></p>Formula:C12H4Br6OColor and Shape:White To Off-WhiteMolecular weight:643.582-(Chloromethoxy)acetic Acid Ethyl Ester
CAS:Controlled Product<p>Applications 2-(Chloromethoxy)acetic Acid Ethyl Ester is used in the preparation of antiviral acyclonucleosides and their metabolites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kutsuma, T. et al.: Heterocycles, 65, 1967 (2005); Hu, L. et al.: Guiy. Yix. Xueb., 33, 546 (2008);<br></p>Formula:C5H9ClO3Color and Shape:NeatMolecular weight:152.583-(3-Amino-4-methylphenyl)-5-isopropylimidazolidine-2,4-dione
Controlled ProductFormula:C13H17N3O2Color and Shape:NeatMolecular weight:247.3N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine-d5
CAS:Controlled Product<p>Applications N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine-d5 is labelled N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine (D199030), a derivative of Mertansine (M257800) which is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.<br>References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)<br></p>Formula:C41D5H50ClN4O12SColor and Shape:White To Off-WhiteMolecular weight:868.4445-Chloro-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
CAS:Controlled Product<p>Applications Intermediate for synthesis of verapamil and analogs.<br></p>Formula:C16H22ClNO2Color and Shape:NeatMolecular weight:295.802-Hydroxy Atorvastatin Calcium Salt
CAS:Controlled Product<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Formula:C66H68CaF2N4O12Color and Shape:White To YellowMolecular weight:1187.354-Aminoacetophenone-13C
CAS:Controlled ProductFormula:CC7H9NOColor and Shape:NeatMolecular weight:136.1561-Naphthoic Acid-d7
CAS:Controlled Product<p>Applications 1-Naphthoic Acid-d7 (cas# 634179-80-9) is a compound useful in organic synthesis.<br></p>Formula:C112H7HO2Color and Shape:NeatMolecular weight:179.22Cesium Carbonate
CAS:Controlled Product<p>Applications Cesium Carbonate is used in the preparation of prodrugs based upon phosphonooxymethyl as HIV-1 attachment inhibitors. Also used in the synthesis of dodecahedral nanocrystals as effective antibacterial agents.<br>References Leahy, D. et al.: Org. Proc. Res. Dev., 17, 1440 (2013); He, J. et al.: Dalton Trans., 42, 15637 (2013);<br></p>Formula:Cs2CO3Color and Shape:White To Off-WhiteMolecular weight:325.82apo-Ipratropium Bromide
CAS:<p>Applications apo-Ipratropium Bromide is an intermediate used in the preparation of quaternary salts of alkaloids.<br>References Ivanov, V., et al.: Farmatsiya17, 18 (1967)<br></p>Formula:C20H28NO2·BrColor and Shape:NeatMolecular weight:394.34Methyl 3-Phenylpropionate(3-Phenylpropionic Acid Methyl Ester)
CAS:Controlled Product<p>Applications 3-Phenylpropionic Acid Methyl Ester is an ester derivative of 3-phenylpropionic acid that is sometimes present in fragrance ingredients.<br>References Belsito, D. et al.: Food Chem. Toxicol., 49, S256 (2011):<br></p>Formula:C10H12O2Color and Shape:NeatMolecular weight:164.22H,2H,3H,3H-Perfluorooctanoic Acid
CAS:Controlled Product<p>Applications 2H,2H,3H,3H-Perfluorooctanoic Acid is used in analytical studies for the identification of precursors and biodegradable products of perfluorinated and polyflorinated compounds using high resolution mass spectrometry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yamamoto, A., et al.: Anal. Bioanal., Chem., 406, 4745 (2014)<br></p>Formula:C8H5F11O2Color and Shape:Off-WhiteMolecular weight:342.11Bromfenac Sodium Sesquihydrate
CAS:Controlled Product<p>Applications Bromfenac is a non-steroidal anti-inflammatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), MacDonald, J., et al.: Toxicol. Sci., 110, 40 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Formula:C15H11BrNO3·2Na·3H2OColor and Shape:Light YellowMolecular weight:766.342-Phenylbutyrylurea
CAS:<p>Applications 2-Phenylbutyrylurea is used in the synthesis and discovery of novel trypanosomicidal drug-like compounds which is useful in the treatment of diseases. A degradation product of Phenobarbitol (P316760).<br>References Castillo-Garit, J. et al.; Eur. J. Med. Chem., 46, 3324 (2011);<br></p>Formula:C11H14N2O2Color and Shape:NeatMolecular weight:206.24(-)-Lupinine
CAS:<p>Applications (-)-Lupinine is an alkaloid capable of counteracting ethanol anesthesia.<br></p>Formula:C10H19NOColor and Shape:NeatMolecular weight:169.261-(6-Amino-9H-purin-2-yl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (>85%)
CAS:Controlled Product<p>Applications 1-(6-Amino-9H-purin-2-yl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester is an intermediate in synthesizing 1-(6-Amino-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide (A629440), it is used in the synthetic preparation of regadenoson and intermediates by using cyclocondensation, amidation and condensation as the key steps.<br>References Chai, J.; et al.: Faming Zhuanli Shenqing. 14pp.Patent 2015 CODEN:CNXXEV<br></p>Formula:C11H11N7O2Purity:>85%Color and Shape:NeatMolecular weight:273.25α-Amylcinnamyl Alcohol
CAS:Controlled Product<p>Applications Alpha-Amylcinnamyl Alcohol (cas# 101-85-9) is a useful research chemical.<br></p>Formula:C14H20OColor and Shape:NeatMolecular weight:204.313-Ethyl Adenine-d5 (2% d0)
CAS:Controlled Product<p>Applications 3-Ethyl Adenine-d5 (2% d0) (cas# 147028-85-1) is a compound useful in organic synthesis.<br></p>Formula:C72H5H4N5Color and Shape:White To Off-WhiteMolecular weight:168.217-Hydroxy-1,3-naphthalenedisulfonic Acid Dipotassium Salt
CAS:Controlled Product<p>Applications 7-Hydroxy-1,3-naphthalenedisulfonic acid is a coupling component used to prepare heterocyclic monoazo dyes.<br>References Naik, D., et al., Dyes and Pigments., 14,1 (1990); Bilimoria, J., et al.: Colourage, 57, 72 (2010)<br></p>Formula:C10H6O7S2·2KColor and Shape:Off White SolidMolecular weight:380.48Methyl Indole-2,4,5,6,7-d5-3-acetate
CAS:Controlled Product<p>Applications Methyl Indole-2,4,5,6,7-d5-3-acetate is an isotopic analog of Methyl Indole-3-acetate (M313475), an important phytohormone.<br>References Quittenden, L., et al.: Plant Physiol., 151, 1130 (2009), Jiraskova, D., et al.: J. Phycol., 45, 108 (2009),<br></p>Formula:C11H6D5NO2Color and Shape:NeatMolecular weight:194.24Adenosine-13C5
CAS:<p>Stability Hygroscopic<br>Applications Labelled nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010), Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010),<br></p>Formula:C513C5H13N5O4Color and Shape:White To Off-WhiteMolecular weight:272.206α-Hydroxy Norethindrone Acetate
CAS:Controlled Product<p>Applications An oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.<br>References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),<br></p>Formula:C22H28O4Color and Shape:Off-WhiteMolecular weight:356.46Hydroxocobalamin Acetate
CAS:Controlled Product<p>Applications Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).<br>References Kaczka, E.A., et al.: Science, 112, 354 (1950), Friedrich, W., et al.: Vitamins, 837 (1988), Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993),<br></p>Formula:C64H91CoN13O16PColor and Shape:Dark RedMolecular weight:1388.39Digoxigenin Bisdigitoxoside
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Formula:C35H54O11Color and Shape:NeatMolecular weight:650.801,5-Diisocyanatonaphthalene
CAS:Controlled Product<p>Applications 1,5-DIISOCYANATONAPHTHALENE (cas# 3173-72-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C12H6N2O2Color and Shape:White To Off-WhiteMolecular weight:210.19Benoxaprofen
CAS:Controlled Product<p>Applications A non-steroidal anti-inflammatory ophthalmic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mathur, K., et al.: Bioorg. Med. Chem., 11, 1915 (2003), Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007), Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009),<br></p>Formula:C16H12ClNO3Color and Shape:NeatMolecular weight:301.722,3-Dibromoanthracene
CAS:Controlled Product<p>Applications 2,3-Dibromoanthracene is a useful synthetic intermediate. It is used to synthesize various acenes and acene derivatives such as Acenaphth[1,2-b]anthracene (A130745) which is mutagenic.<br>References Toyota, S., et al.: Sci. Syn., 45, 745 (2010); Durant, J., et al.: Mutat. Res-Genet. Tox., 371, 123 (1996)<br></p>Formula:C14H8Br2Color and Shape:NeatMolecular weight:336.028-((4-Amino-3-nitrophenyl)diazenyl)-7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium Chloride (Technical Grade)
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications 8-((4-Amino-2-nitrophenyl)diazenyl)-7-hydroxy-N,N,N-trimethylnaphthalen-2-aminium Chloride is used in the preparation of hair dyes and color intensifiers in cosmetics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moeller, H., Oberkobusch, D.: Ger. Offen. (2003), DE 10148841 A1 20030410<br></p>Formula:C19H20N5O3·ClColor and Shape:NeatMolecular weight:366.39 + 35.454,4’-Bis(4”-aminobenzenesulfonyl) Diphenyl Ether Dihydrochloride
CAS:<p>Applications The diamino arylene disulfones used in polyamido polysulfone thermoplastics and intermediates.<br></p>Formula:C24H20N2O5S2•2HClColor and Shape:NeatMolecular weight:553.47NN'-Bis(2-hydroxyethyl)urea
CAS:<p>Applications NN'-Bis(2-hydroxyethyl)urea (cas# 15438-70-7) is a useful research chemical.<br></p>Formula:C5H12N2O3Color and Shape:NeatMolecular weight:148.162-Nitrophenol-3,4,5,6-d4
CAS:Controlled Product<p>Applications 2-Nitrophenol-3,4,5,6-d4 (CAS# 93951-78-1) is a useful isotopically labeled research compound.<br></p>Formula:C6D4HNO3Color and Shape:NeatMolecular weight:143.13Prasugrel Thiolactone-d5 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications A labelled inactive metabolite of Prasugrel (P701150).<br>References Sugidachi, A., et al.: Br. J. Pharmacol., 129, 1439 (2000); Takahashi, S., et al.: J. Pharm. Sci., 97, 5434 (2008); Williams, E., et al.: Drug Metab. Dispos., 36, 1227 (2008); Hagihara, K., et al.: Xenobiotica, 39, 218 (2009);<br></p>Formula:C18H13D5FNO2SColor and Shape:NeatMolecular weight:336.435N-Nitroso Nipecotic Acid-d4 (Major)
CAS:Controlled Product<p>Applications A major urinary labelled metabolite of N-nitrosoguvacoline (N527625) and N-nitrosoguvacine, found in cigarette tobacco.<br>References Ernst, H., et al.: Carcinogenesis, 8, 1843 (1987),<br></p>Formula:C6H6D4N2O3Color and Shape:Off-White To BeigeMolecular weight:162.18(S)-Ramelteon Metabolite M-II
CAS:Controlled Product<p>Applications S-Ramelteon Metabolite M-II is a metabolite of Ramelteon in serum (M-II).<br>References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004); Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004); Kato, K., et al.: Neuropharmacology, 48, 301 (2005); Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006)<br></p>Formula:C16H21NO3Color and Shape:NeatMolecular weight:275.342-Hydroxy Oleic Acid
CAS:Controlled Product<p>Applications An oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive.<br>References Llado, V. et al.: J. Cell. Molec. Med., 14, 659 (2010); Alemany, R. et al.: J. Lip. Res., 47, 1762 (2006); Martinez, J. et al.: J. Pharmacol. Exp. Therap., 315, 466 (2005);<br></p>Formula:C18H34O3Color and Shape:Off White SolidMolecular weight:298.46Androsterone Sulfate Sodium Salt
CAS:Controlled ProductFormula:C19H29O5S·NaColor and Shape:White To Off-WhiteMolecular weight:392.40Betamethasone Tripropionate
CAS:<p>Impurity Betamethasone Dipropionate EP Impurity G<br>Applications Betamethasone Tripropionate (Betamethasone Dipropionate EP Impurity G) is a Betamethasone (B327000) related compound.<br>References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),<br></p>Formula:C31H41FO8Color and Shape:NeatMolecular weight:560.65Hydroxy Urea
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Formula:CH4N2O2Color and Shape:White SolidMolecular weight:76.05Fulvestrant 9-Sulfone
CAS:Controlled Product<p>Impurity Fulvestrant EP Impurity B<br>Applications A metabolite of Fulvestrant (F862500).<br>References Rao, P., et al.: J. Steroid Biochem., 25, 417 (1986), Wakeling, A., et al.: J. Steroid Biochem. Mol. Biol., 43, 173 (1992), DeFriend, D., et al.: Cancer Res., 54, 408 (1994),<br></p>Formula:C32H47F5O4SColor and Shape:NeatMolecular weight:622.77Higenamine Hydrobromide Salt
CAS:Controlled Product<p>Applications Higenamine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.<br>References Ha, Y. et al.: Apoptosis., 17, 463 (2012);<br></p>Formula:C16H18BrNO3Color and Shape:Off-WhiteMolecular weight:352.22Desacetyl Diltiazem
CAS:<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Formula:C20H24N2O3SColor and Shape:White To BrownMolecular weight:372.48Atorvastatin Ethyl Ester
CAS:Controlled Product<p>Applications Atorvastatin (A791750) impurity.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);<br></p>Formula:C35H39FN2O5Color and Shape:Off White SolidMolecular weight:586.69Allo-3α-tetrahydro Cortisol
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Cortisol (H714615).<br>References Quinkler, M., et al.: J. Clin. Endocrinol. Metab., 88, 2384 (2003), Draper, N., et al.: J. Endocrinol., 186, 251 (2005), Kotlowska, A., et al.: Clin. Biochem., 42, 448 (2009),<br></p>Formula:C21H34O5Color and Shape:Off White SolidMolecular weight:366.49Benazepril Acyl-β-D-glucuronide
Controlled Product<p>Stability Hygroscopic<br>Applications Used as an antihypertensive.This compound is very unstable in solution and will hydrolyze readily to give benazapril.<br></p>Formula:C30H36N2O11Purity:>85%Color and Shape:NeatMolecular weight:600.614-Bromobenzoic Acid Methyl Ester
CAS:<p>Applications 4-Bromobenzoic Acid Methyl Ester is halogenated benzoate used as a reagent in organic synthesis. 4-Bromobenzoic Acid Methyl Ester can be used to stimulate microbial dechlorination of PCBs. 4-Bromobenzoic Acid Methyl Ester is also used in the preparation of stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer.<br>References Wilbur, D.S. et al.: J. Nuclear Med., 30, 216 (1989); DeWeerd, K.A. et al.: Environ. Sci. Technol., 33, 2057 (1999);<br></p>Formula:C8H7BrO2Color and Shape:Off-WhiteMolecular weight:215.04
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