Pharmaceutical Standards

<p>Cyclohexylstatine is a glycopeptide antibiotic that inhibits the synthesis of collagen in animals and humans. It also has been shown to have anticancer activity. Cyclohexylstatine works by inhibiting the biosynthesis of collagen, which is an important component of skin, ligaments, and tendons. The molecule was synthesized in 1975 and has been used as a pharmaceutical agent since 1980. Cyclohexylstatine is the first anti-collagen drug to be developed for use in humans. It has been shown to be effective against autoimmune diseases such as rheumatoid arthritis but not against cancer cells or bacteria. Cyclohexylstatine binds to the zymogen form of collagenase and inhibits its activity. This inhibition leads to an accumulation of polysaccharides in the extracellular matrix that are converted into oligosaccharides by glycosidases present in tissue fluids. These oligosaccharides inhibit collagen synthesis by binding to</p>

<p>6-Bromonaphthalen-1-ol is a compound that has shown antimicrobial and antifungal activity. It is the most potent of the naphthoxazines tested to date, with an MIC of 0.04 µg/ml against Escherichia coli. 6-Bromonaphthalen-1-ol was synthesized by reacting 1,2,4-trihydroxybenzene with bromine gas in the presence of mercuric chloride catalyst. The compound was hydrolyzed for elemental analysis and found to be C7H4BrO. Elemental analysis yielded a weight percentage of 71% carbon, 13% hydrogen, 3% bromine, and 12% oxygen. The x-ray diffraction pattern showed peaks at 2θ values of 22.3° (100), 26.5° (101), 33.7° (102), 40° (104), 44° (105) and 62°</p>

<p>Please enquire for more information about (D-Phe7)-Somatostatin-14 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,3'-Dichlorodiphenylacetylene is a versatile building block that is used in the synthesis of complex compounds. It has been used as a reagent and as a speciality chemical for research purposes. This chemical can be used as a useful building block for the synthesis of other compounds, or it can be reacted with other compounds to form new compounds. 3,3'-Dichlorodiphenylacetylene is also an intermediate in organic syntheses and has been shown to react with many different types of molecules.</p>

<p>Please enquire for more information about 2,2'-Azanediylbis(propan-1-ol) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Isovaleryl-Val-Val-Sta-OEt is a peptide hormone and active inhibitor of the enzyme pepsin. This drug has been shown to have proteolytic activity in vitro, with a pepsin rate constant of 0.0015 min−1. It also inhibits the protease activity of trypsin, chymotrypsin, and elastase at a similar rate. Isovaleryl-Val-Val-Sta-OEt has been shown to be an active inhibitor of polymerase chain reaction (PCR) and reverse transcriptase activities. This drug is not absorbed through skin and can be used as a nonimmunogenic reagent for biochemical studies on water permeability and signal peptide sequences in biological samples.</p>

<p>Osteostatin is a recombinant human protein that inhibits bone growth by binding to and neutralizing the effect of forskolin. Osteostatin also has an inhibitory effect on cancer cells, as it inhibits mitochondrial pathways and prevents the activation of factor receptors. Osteostatin blocks the synthesis of cAMP, which is necessary for cell proliferation in cancer cells. The inhibition of cAMP levels leads to a decrease in the production of proteins that stimulate bone growth, such as runx2.</p>

<p>Please enquire for more information about ([ring-D5]Phe6)-Somatostatin-14 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-4-(7-hydroxy-4-coumarinyl)-Abu-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Tert-butyl sarcosinate hydrochloride is a synthetic alkene that has been shown to have potential as a treatment for Parkinson's disease. It binds to the phosphate group of ATP and inhibits creatine kinase, which is an enzyme involved in the production of energy in cells. Tert-butyl sarcosinate hydrochloride can also be used for the pharmacological treatment of other diseases such as diabetes, Alzheimer's disease, and cancer. This molecule has been shown to be effective when combined with recombinant proteins and enzymatic methods for guanylating DNA.

<p>5-Bromo-2-nitropyridine is a hydrogen bond donor. It is an organic molecule with the chemical formula C5H5BrN3. The compound has been used in the synthesis of other molecules, such as nicotinic acetylcholine and mitochondrial membrane potential inhibitors. 5-Bromo-2-nitropyridine is also a good candidate for cancer treatment due to its ability to inhibit cell cycle progression at G2/M phase. 5-Bromo-2-nitropyridine can be synthesized by reacting 2,4,6-trinitrobenzenesulfonic acid with bromine and potassium carbonate in a reaction vessel at 200 °C for about 30 minutes.</p>

<p>Please enquire for more information about Cortistatin-29 (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Used in the synthesis of 6,6'-substituted BINOL chiral ligands</p>

<p>Please enquire for more information about Biotinyl-epsilon-aminocaproyl-D-Phe-Pro-Arg-chloromethylketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ([ring-D5]Phe3)-Octreotide acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about Biotinyl-Obestatin (rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about AMCA-Glu-Glu-Lys-Pro-Ile-Ser-Phe-Phe-Arg-Leu-Gly-Lys(biotinyl)-NH2 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Mevalonic acid lactone is a natural compound that has been shown to have an effect on mitochondrial membrane potential. It has also been shown to inhibit the drug transporter P-glycoprotein, which is involved in the transport of drugs out of cells. Mevalonic acid lactone has also demonstrated an anti-inflammatory effect, as it inhibits the production of TNF-α and IL-6 in human serum. This compound also possesses antioxidant properties, which may be due to its hydroxyl group and phenoxy groups. Mevalonic acid lactone can be used as a model system for sesquiterpene lactones, and it is able to improve mitochondrial functions by inhibiting pyrazole ring formation.</p>

<p>Please enquire for more information about Acetyl-(Asn30,Tyr32)-Calcitonin (8-32) (salmon I) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Methoxy-4-(trifluoromethyl)coumarin is a potent and selective aromatase inhibitor. It inhibits the activity of the enzyme, which converts testosterone to estradiol. The inhibition of this enzyme may be beneficial in the treatment of breast cancer. This compound has also been shown to inhibit the activity of P450 enzymes and coumarin derivatives, which are involved in drug metabolism and detoxification.</p>

<p>7b-Hydroxycholesterol is a cholesterol metabolite that is formed from 7-alpha-hydroxylase by cytochrome P450. It has been shown to induce apoptosis in a number of carcinoma cell lines, including HL-60 cells and human prostate cancer cells. 7b-hydroxycholesterol was also shown to be an effective inducer of the formation of body structures by cultured cells. It has been found to be potent inducers of the synthesis of oxysterols, which are natural compounds that have been shown to inhibit viral replication. The effects on body formation and viral inhibition may be due to its ability to bind to the mitochondrial membrane potential, inhibiting ATP binding cassette transporter and enzyme activities.</p>

<p>Cis-3-hexenal is a fatty acid that is found in various foods, including soybean and corn oils. It can be used as a chemical substrate to measure the activity of lipoxygenases, enzymes that catalyze the formation of hydroperoxides from polyunsaturated fatty acids. Cis-3-hexenal is also an insect attractant and has been shown to have antifungal properties against plant pathogens such as Phytophthora infestans. This chemical compound has also been shown to inhibit protein synthesis in cells and to be able to react with DNA. Cis-3-hexenal - stabilised: 50% in triacetin</p>

<p>Please enquire for more information about (7-Diethylaminocoumarin-3-yl)carbonyl-Amyloid b-Protein (1-40) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about Neuronostatin-13 (human, canine, porcine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about Chorionic Gonadotropin-b (109-145) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Homo-L-tyrosine hydrobromide (HLTB) is a prodrug that is converted to L-3,4-dihydroxyphenylalanine (L-dopa) in vivo. It is used as an immunomodulator by stimulating the immune system and reducing inflammation. HLTB has been shown to have anti-inflammatory effects on the production of cytokines and chemokines, which are important for tumor growth and metastasis. HLTB is also known to inhibit tyrosine kinase, which plays a role in the development of some cancers.</p>

<p>Fmoc-3-(2-naphthyl)-L-alanine is a supramolecular compound that functions as an inhibitor of prostate cancer cells. It inhibits the uptake of metal chelates by prostate cancer cells and stabilizes them, which may lead to a diagnostic and therapeutic agent for prostate cancer. Fmoc-3-(2-naphthyl)-L-alanine has also been shown to inhibit the growth of human serum prostate cancer cells in vitro and in vivo models. This molecule is a bifunctional compound that can be used as both an antigen and a surrogate for cytosolic prostate specific antigen (PSA) levels. Fmoc-3-(2-naphthyl)-L-alanine has been shown to bind to the PSA protein, which is normally found on the surface of prostate epithelial cells. This binding prevents it from being released into the blood circulation, where it would otherwise be measured by a PSA test</p>

<p>4'-Cyclohexylacetophenone is a chalcone that is prepared from hexamethylenetetramine and cyclohexanone. The reaction of 4'-cyclohexylacetophenone with methylthio-1,3-dithiane in the presence of proton irradiation yields a mixture of products. 4'-Cyclohexylacetophenone has been used as a precursor for preparing other chalcones. This compound can be readily prepared by chlorinating 1,3-diphenylpropane to give 3-chlorocyclohexylacetic acid followed by hydrolysis to the ketone. It is also used as a starting material for synthesis of heterocycles such as benzofuran and indole.</p>

<p>2-Aminoacetophenone hydrochloride is a chemical compound that is used in analytical chemistry as a reagent for the determination of protein and amino acid concentrations. This reagent can be prepared in various forms, depending on the type of analysis being performed. 2-Aminoacetophenone hydrochloride is used to determine the concentration of free amino acids in a sample by binding to it. It can also be used for determining the concentration of bound amino acids by reacting with them with hydrochloric acid. 2-Aminoacetophenone hydrochloride is an excellent substrate for matrix effect, which may cause errors in measurement due to interference from other substances present in the sample. The use of light exposure reduces this problem by removing interfering substances from the sample.</p>

<p>Please enquire for more information about Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2',4'-Dichlorochalcone is a chalcone that has been stabilized by the attachment of two chlorine atoms. The crystal structure of 2',4'-Dichlorochalcone contains intermolecular hydrogen bonds and dihedral angles. The molecule also has intramolecular hydrogen bonds and dihedral angles, which are formed by the propenone and benzene groups. 2',4'-Dichlorochalcone can be used to create new drugs for antifungal, anti-inflammatory, or anti-cancer treatments.</p>

<p>Vitamin A acetate is a retinoid that can be used to supplement dietary intake of vitamin A. It is a synthetic retinoid and is chemically similar to retinol, the natural form of vitamin A. Vitamin A acetate has been shown to have antioxidant properties in vitro and in vivo, which are likely due to its ability to regenerate endogenous antioxidants. This agent also has pro-apoptotic effects on cells that are exposed to oxidative injury or exhibit redox potentials below -400 mV. In addition, it significantly reduces oxidative injury caused by pharmacological agents such as doxorubicin or bleomycin.</p>

<p>Phenol,2,2'-sulfonylbis[3,4,6-trichloro] is a sulfate-containing compound that has been shown to stimulate the immune system and activate mitogen-activated protein kinases (MAPKs) in mosquitoes. The inclusion of this substance in vaccines may lead to increased immunity against various diseases. Phenol,2,2'-sulfonylbis[3,4,6-trichloro] has also been shown to reduce cancer cell proliferation by modulating antigen-presenting cells and inducing apoptosis in ovarian cancer cells. This substance can be used as a cost-effective alternative to dextran sulfate for generating pluripotent stem cells from adult cells and can also be used as a scalable process for generating pluripotent cells from human amniotic fluid.</p>

<p>Please enquire for more information about Biotinyl-(Leu8,D-Trp22,Tyr25)-Somatostatin-28 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 9,11-Anhydrobudesonide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Homoharringtonine is a natural drug that has been used for the treatment of cancer and other diseases. It is an antitumor agent that inhibits cell growth by affecting DNA synthesis, RNA synthesis, protein synthesis, and the activity of enzymes. Homoharringtonine also has antineoplastic effects and can be used to treat leukemia. Homoharringtonine binds to DNA in a ring-opening reaction with yields of up to 20%. This compound can be synthesized from phenylalanine and substituted with a trisubstituted benzene ring. It also catalyzes the conversion of an enamine into an iminium ion, which reacts with a second molecule of enamine to form a keto-enamine.</p>

<p>1,7-Dimethylnaphthalene is a molecule that can be found in various aromatic hydrocarbons. It has been shown to have an inhibitory effect on the growth of cancer cells. 1,7-Dimethylnaphthalene is also used as a biological treatment in industrial chemicals. It is known to increase the rate of fatty acid biosynthesis and inhibits the production of certain enzymes that are involved in cancer development.</p>

<p>4-Methyl-3-nitrophenyl isocyanate (4MPN) is a chiral diisocyanate that can be used as an activated diisocyanate. 4MPN is prepared by the carbonylation of 3-nitrobenzaldehyde and xylene with hydrogen chloride in the presence of a catalyst. Impurities, such as chlorides or sulfurs, can be detected using surface methodology techniques. The feedstock for this compound is usually xylene, which has a high boiling point. This product contains reactive functional groups that can be used to modify surfaces and create polyurethane products.</p>

<p>Triglycerol monolaurate (GLA) is a fatty acid that can be synthesized by reacting glycerol with lauric acid. It has been shown to have antimicrobial properties, inhibiting the growth of fungi such as flavus and staphylococcus. GLA also inhibits the production of lipase and protease, enzymes that are required for the digestion of dietary fats. GLA has been used in infant formulas to inhibit the growth of bacteria, such as p. aeruginosa, which may cause infantile diarrhea. Triglycerol monolaurate is also used as dietary supplement to treat eczema due to its inhibitory effect on inflammatory cytokines such as tumor necrosis factor-α (TNF-α).</p>

<p>Camphorquinone is an inorganic acid that is a component of the topical anaesthetic hydrochloride, which is used for the treatment of pain. Camphorquinone has a hydroxyl group, which can be replaced with other groups to produce different compounds. It has been shown to have a kinetic data for the polymerase chain reaction and to inhibit the activity of 4-dimethylaminobenzoic acid. Camphorquinone has also been shown to be effective against dental plaque and rat liver microsomes. The clinical relevance of camphorquinone has not yet been determined, but it may have an effect on hydrochloric acid production by zirconium oxide light emission.</p>

<p>1,1-Diethylurea is a 5-nitrosalicylic acid amide derivative. It is used as a reagent to synthesize other chemicals, such as 3,5-dinitrosalicylic acid and N-acetyl-2,6-diaminopurine. The reaction intermediates of this compound are chloride and liquid chromatograph with azides and quinoline derivatives. The molecular modeling and reaction products of 1,1-diethylurea are organic solution and pharmaceutical preparations. Fatty acids can be used to manufacture this product.</p>

<p>Please enquire for more information about 3'-[2- Cyanoethyl N, N- bis(1- methylethyl) phosphoramidite]-5'- O- [bis(4- methoxyphenyl) phenylmethyl] - 2'- O- methyl- N- [2- [4- (1- methylethyl) phenoxy] acetyl] -guanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>L-Isoleucine beta-naphthylamide is an amide derivative of L-isoleucine and 2-naphthylamine, which are carboxylic acid derivatives. The condensation of these two substances leads to the formation of a new compound with a carboxy group and an amino group.</p>

<p>Please enquire for more information about 5-Hydroxy-2,3-dihydronaphthalene-1,4-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-(2-Naphthyloxy)propanoic acid is a naphthalene derivative that is found in the plant species Carthamus tinctorius. It has been shown to have potent antagonist activity against the NMDA receptor, as well as antinociceptive and analgesic properties in vivo. 2-(2-Naphthyloxy)propanoic acid also shows potent anti-inflammatory and cardioprotective effects in vitro and in vivo. 2-(2-Naphthyloxy)propanoic acid can be used for the treatment of bone cancer, congestive heart failure, diabetic neuropathy, or other disorders of the peripheral nervous system.</p>

3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine (BDBMU) is a pyrimidine derivative that can be used as an antiviral drug. It inhibits the synthesis of DNA and RNA by inhibiting viral polymerase. BDBMU is a prodrug of uracil, which is converted to the active compound in tissues. The benzoylation reaction produces a fluorine atom at C5, which increases its potency. This drug has been shown to have minimal toxicity in tumor cells and has been used for the treatment of leukemia and other cancers.

<p>Terflavin B is a natural product that has been shown to have autophagy-inducing properties. Terflavin B induces autophagy by increasing the metabolic rate and inhibiting the synthesis of proteins. This product has been shown to increase the cancer cell's sensitivity to chemotherapy, which may be due to its ability to induce reactive oxygen species. In addition, terflavin B can protect against drug interactions by inhibiting the activity of cytochrome P450 enzymes. It also inhibits the growth of resistant microorganisms such as chronic kidney and bladder infections. Terflavin B contains tannins and ellagitannins, which have antimicrobial activities that are effective against bacteria, yeast, and fungi.</p>

<p>Perillaldehyde is a natural compound that has been used in food and medicine for centuries. It is an antimicrobial agent with dextran sulfate, which is a sugar polymer that inhibits the growth of fungi and bacteria. Perillaldehyde also has been shown to inhibit the energy metabolism of microorganisms by decreasing ATP production. Perillaldehyde has also been shown to have genotoxic activity, as it can cause DNA strand breaks. This compound also causes oxidative stress in cells by reducing mitochondrial membrane potential and inducing reactive oxygen species (ROS). Perillaldehyde has acute toxicities, as it causes electrochemical impedance spectroscopy changes that indicate cell death.</p>

Trans,cis-2,6-Nonadienal is a fatty acid derivative with an unsaturated 2,6-nonadiene structure. It is an inhibitor of the enzyme fatty acid synthase, which catalyzes the formation of long-chain polyunsaturated fatty acids. Trans,cis-2,6-Nonadienal has been shown to inhibit v79 cells and ester compounds that are used in analytical methods for measuring fatty acids. It is also able to inhibit lysine residues and it can be used as a reactive antioxidant system in mammalian cells. Trans,cis-2,6-Nonadienal has shown a profile of activities that includes inhibition at multiple endpoints involving noncompetitive inhibition as well as antioxidant activity.

<p>Vitamin K is a fat-soluble vitamin that is required for blood coagulation. The major form of vitamin K in the body is the chemically similar menaquinone. Vitamin K1, also known as phylloquinone, is synthesized by plants and bacteria and can be found in green leafy vegetables, broccoli, cabbage, Brussels sprouts, kale, spinach, soybean oil and margarine. It has been shown to be an effective supplement for treating hypoprothrombinemia (low levels of prothrombin) in infants and tissues. The terminal half-life of vitamin K1 is about 20 days.</p>

<p>Previtamin D2 is a chemical compound that is the natural form of vitamin D. It is found in human skin and can be converted to vitamin D3 by exposure to sunlight or artificial ultraviolet light. Previtamin D2 has been shown to have anti-cancer properties and may have potential as a dietary supplement. Previtamin D2 has been used for the treatment of dry skin, although it has not been approved for this use. The most common use of previtamin D2 is in wastewater treatment, where it is added to water as an anticancer agent. This process involves exposing the water to ultraviolet radiation and then adding previtamin D2. The previtamin D2 reacts with chlorine bleach, which releases hydrogen peroxide and creates disinfectant byproducts that are less toxic than those created by chlorine alone. Previtamin D2 can also be used in analytical chemistry as an intermediate in the production of vitamin D3 from cholesterol. It can be used as a sample preparation reagent when chromatographic science</p>

<p>Please enquire for more information about Desmethylene paroxetine hydrochloride salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 6-(Bromomethyl)-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

DL-alpha-Methyl-m-tyrosine (AMT) is a drug that is used to treat Parkinson's disease. It is an inhibitor of the uptake of dopamine and norepinephrine, which are neurotransmitters in the central nervous system. AMT blocks the action of a specific enzyme called aromatic L-amino acid decarboxylase, preventing the conversion of these neurotransmitters into their inactive metabolites. AMT also has been shown to be an antidepressant drug with stimulant properties. This may be due to its ability to inhibit uptake and release of monoamines in brain tissue.

<p>Please enquire for more information about 6-Hydroxy doxazosin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(2,4-Dinitrophenyl)butanoicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about Gly-arg-4-methoxy-beta-naphthylamide dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Eosine-5-isothiocyanate is a fluorescent probe that has affinity for the interstitium of the kidney. This compound inhibits the transport of organic compounds across the renal tubular epithelium, and it is used as a marker for renal function. Eosine-5-isothiocyanate binds to molybdate with high affinity and can be used to measure its concentration in blood plasma. The inhibitory potency of eosine-5-isothiocyanate on carboxylates was tested by perfusing phenolphthalein through a rat's kidneys. Phenoxy dicarboxylates were found to be more potent inhibitors than phenoxy monocarboxylates, but not as potent as eosine-5-isothiocyanate itself. The spectrum of eosine-5-isothiocyanate is in the visible range, so this compound can be detected using</p>

<p>2-Hydroxy-6-nitronaphthalene is a colourless, crystalline solid that is soluble in water and polar organic solvents. It has been used as a coupling agent for chromium compounds, such as dichromates and chromates. 2-Hydroxy-6-nitronaphthalene can be diazotised to form an orange compound. This reaction occurs under acidic conditions, but the product is stable at alkaline pH levels. The product of this reaction is an asymmetric monoazo dye that has trivalent chromium atoms covalently bonded to it. Hydrogen atoms are present on the nitrogen atoms of the molecule. 2-Hydoxy-6-nitronaphthalene can also be used to produce sulfate esters, which are typically used in organic synthesis reactions involving sulfuric acid or hydrogen sulfate ion donors.</p>

<p>2-Propyl valeraldehyde is a solvent that is used in pharmaceutical preparations and has been shown to inhibit the activity of aldehyde dehydrogenase, an enzyme that catalyzes the oxidation of alcohols and aldehydes. 2-Propyl valeraldehyde also inhibits the formation of carboxylic acids by competitive inhibition with metal ions such as zinc. The deuterium isotope effect has been used to show that 2-propyl valeraldehyde is metabolized by deuterium exchange. Mass spectrometric detection has shown that this compound contains a carbonyl group (C=O). This compound can be used as an intermediate in organic synthesis reactions, but it also has convulsant effects.</p>

<p>N-(5-Aminopentyl) methotrexate amide-LC-biotin is a specialized bioconjugate, derived through the conjugation of methotrexate, an established antifolate drug, with an LC-biotin moiety. This product is synthesized by covalently linking methotrexate, which is known for its role in cancer therapy through the inhibition of dihydrofolate reductase (DHFR), to a biotin moiety via a long-chain spacer. The resultant bioconjugate retains the therapeutic effects of methotrexate, particularly in its ability to interrupt nucleotide synthesis, thereby affecting cell division in rapidly proliferating cancer cells.The inclusion of biotin in the structure allows for facile attachment to avidin or streptavidin-labeled systems, facilitating targeted delivery and enhanced detection in molecular and cellular studies. The primary application of N-(5-Aminopentyl) methotrexate amide-LC-biotin lies in the realm of targeted drug delivery and advanced research into methotrexate metabolism. By leveraging the high affinity of biotin-streptavidin interactions, researchers can effectively study the biodistribution and cellular uptake of methotrexate, advancing cancer therapeutic strategies and providing insights into antifolate drug mechanisms at the molecular level.</p>

1-Vinylnaphthalene is a monomer that has been shown to polymerize through cationic polymerization. It is reported to have high resistance, as well as fluorescence properties. The magnetic resonance spectroscopy of 1-vinylnaphthalene showed the presence of a hydroxyl group and a fatty acid side chain. The kinetic data for 1-vinylnaphthalene shows an increase in the dry weight with increasing concentration, which can be attributed to the hydroxyl group and the fatty acid side chain. Patterning experiments have also been conducted on 1-vinylnaphthalene films using hydrogen fluoride, showing that it can be used for patterning purposes.

<p>Oxychelidonine is a chemical compound that is extracted from the leaves of the Oxycoccus vernus plant. Studies have shown that oxychelidonine has significant cytotoxicity against various cancer cells, including those of the breast, prostate, and colon. It is believed to induce apoptotic cell death by inhibiting DNA synthesis and by blocking protein synthesis in cancer cells. Oxychelidonine also inhibits bacterial growth. The extract shows significant cytotoxicity against gram-negative bacteria such as Escherichia coli and Salmonella typhimurium. It has been shown to inhibit the growth of Aspergillus fumigatus, which is a fungus that causes aspergillosis, a type of lung infection. Oxychelidonine can be used in moxibustion treatments for certain conditions such as bronchitis or asthma. Moxibustion involves burning an herb called mugwort (Artemisia vulgaris) on or</p>

<p>Futalosine is a fatty acid that inhibits the reaction mechanism of certain enzymes. It binds to the enzyme and prevents its activity by binding to an allosteric site on the enzyme, thereby blocking the active site. This inhibition can be reversed by adding an activator molecule, such as chorismate. Futalosine has been shown to inhibit papilloma virus and human pathogens but not bacterial species. It is also a natural compound that is found in plants and other organisms. The type species for futalosine is Choristoma mexicanum.END&gt;</p>

<p>Phenylalanine betaine is a naturally occurring amino acid that is found in food. Phenylalanine betaines are used as a model system for studying the effects of hydroxyl groups on protein structures and functions. It can be found in urine samples, which indicates its presence in the body. The molecular modeling of phenylalanine betaine has shown that it can function both as an amino acid and a beta-hydroxy acid. Its inhibition constant is 3.5 µM, which indicates that it may have an antibacterial activity.</p>

<p>Uroporphyrin I dihydrochloride is a facilitator of carbohydrate metabolism. It is a cofactor for the enzyme dehydrogenase and changes the optical properties of certain compounds. Uroporphyrin I dihydrochloride has been shown to modulate the redox potential in lung cells and inhibit human immunodeficiency virus (HIV) replication by inhibiting coproporphyrin production. This drug has also been shown to have an anticancer effect against both leukemia and colon cancer cell lines. Uroporphyrin I dihydrochloride reacts with oxygen, giving it a luminescent property that can be used to assay for its presence in biological systems.</p>

<p>6'-Hydroxy doxazosin is a drug that belongs to the group of alpha-blockers. It is a potent inhibitor of lipoprotein oxidation, which may contribute to its antiplatelet and hypotensive activities. The effects of 6'-hydroxy doxazosin on cholesterol metabolism are not yet known. Although the drug has been shown to be effective in vivo, it has not been studied in humans.</p>

<p>Please enquire for more information about Methyl 6-nitropyrido[1,2-a]benzimidazole-8-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 7-Hydroxy doxazosin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 20a-Dihydro pregnenolone 3-sulfate sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about Codeine Impurity D including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Applications DL-Methionine methylsulfonium chloride (cas# 3493-12-07) is a useful research chemical.<br></p>

<p>Applications Dihydro Artemisinin (D448360) dimer with anticancer and antiprotozoal activity.<br>References Galal, A. et al.: Bioorg. Med. Chem., 17, 741 (2009); Beekman, A. et al.: Phytother. Res., 10, 140 (1996)<br></p>