Pharmaceutical Standards

Applications 6-methyl-2-oxo-4-[(5,6,7,8-tetrahydronaphthalen-2-yl)amino]-1,2-dihydropyridine-3-carboxylic acid (cas# 1239521-17-5) is a useful research chemical.

Applications Curcumin β-D-Glucuronide Triacetate Methyl Ester-d3 is an intermediate used in the synthesis of Curcumin β-D-Glucuronide-d3 (C838512), which is a labelled analogue of Curcumin β-D-Glucuronide, a metabolite of Curcumin (C838510) in hepatic tissue and portal blood.
References Sharma, O., et al.: Biochem. Pharmacol., 25, 1811 (1976); Colletti, L., et al.: J. Clin. Invest., 85, 1936 (1990); Sharma, R., et al.: Clin. Cancer Res., 7, 1894 (2001);

Applications 5-(2-Fluorophenyl)-5-oxovaleric Acid is used as a reagent in the preparation of indole derivatives which act as cell protective agents. It is also used as a reagent in the catalytic N-nitroso aldol reaction of γ,δ-unsaturated δ-lactones.
References Yamamoto, I., et al.: Preparation of indole derivatives as cell protective agents, WO Patent 9745410, Dec 4, 1997; Yanagisawa, A., et al.: Org. Lett., 14, 2434 (2012);

Applications N-Descyclopropyl N-Allyl Buprenorphine, is the metabolite of Buprenorphine (B689570), an Analgesic that demonstrates narcotic agonist-antagonist properties.
References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976), Rance, M.J., Biochem. Pharmacol., 25, 735 (1976), Heel, R.C., et al.: Drugs, 17, 81 (1979),

Applications Labelled analogue of Crotonobetaine Hydrochloride, a trimethylammonium compound that can be converted into L-Carnitine by Escherichia coli via stereoselective hydration.
References Seim, H. et al.: Eur. Congr. Biotechnol., 1, 481 (1984); Seim, H. et al.: Appl. Microbiol. Biotechnol., 27, 538 (1988);

Applications 2,6-Dimethylanthracene (cas# 613-26-3) is a compound useful in organic synthesis.

Applications (S)-2-(tert-Butoxycarbonylamino)-4-(3-methyl-3H-diazirin-3-yl)butanoic acid is a novel photo-cross linker for live-cell imaging.
References Pan, S., et al.: Angewandte Chemie Int. Ed., 56, 11816(2017)

Applications 6,6'-Methylenebis(2-(tert-butyl)-4-ethylphenol) (cas# 88-24-4) is a useful research chemical.

Applications N-Benzoyl-3-methoxytyrosine is an intermediate used in the synthesis of rac 3-O-Methyl DOPA (M303805), which is an impurity of Levodopa (D533751). A useful marker that can be used to screen for the absense of Aromatic L-amino acid decarboxylase (AADC).
References Tabar, et al.: Pharmacol. Biochem. Behav., 33, 139 (1989), De Souza Silva, et al.: J. Neurochem., 68, 233 (1997), Feigin, A., et al.: Neurology, 57, 2083 (2001), Perera, A., et al.: J. Labelled Comp. Radiopharm., 46, 389 (2003)

Applications Gallacetophenone 3’,4’-Dimethyl ether is a phenolic compound with potential 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity.
References Zheng, C.-D. et al.: Nat. Prod. Comm., 5, 1759 (2010);

Applications β-Cyclogeraniol (cas# 472-20-8) is a compound useful in organic synthesis.

Applications 2,2'-Bis-(trifluoromethyl)biphenyl (cas# 567-15-7) is a useful research chemical.

Applications N-(4-Chlorophenyl)-O-methylisourea Sulfate Salt (~90%) is a cytotoxic agent which displays tumor inhibitory activity.
References Hendry, J. et al.: Brit. J. Pharmacol. Chemother., 6, 201 (1951);

Applications α-Naphthyl-d7 Glycidyl Ether is an intermediate in the synthesis of rac-Propranolol-d7 (P831803) which is the labeled analogue of Propranolol (P831800), a β−Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
References Bond, et al.: Nature, 213, 721 (1967), Hansteen, V., et al.: Br. Med. J., 284, 155 (1982), Diamond, S., et al.: J. Clin. Pharmacol., 28, 193 (1988),