Pharmaceutical Standards
Pharmaceutical standards are a comprehensive set of reference materials essential for ensuring the safety, efficacy, and quality of pharmaceutical products. This category includes standards for active pharmaceutical ingredients (APIs), which are the core components responsible for therapeutic effects. Additionally, it covers compounds and metabolites relevant to both the pharmaceutical and veterinary industries, providing benchmarks for the accurate measurement and analysis of these substances. Nitrosamine control standards are crucial for detecting and mitigating potentially harmful nitrosamines in drug formulations. Toxicology standards help assess the safety and potential adverse effects of pharmaceutical compounds. Furthermore, enzyme activators and inhibitors standards are vital for research and development, enabling precise studies of biochemical pathways and drug mechanisms. These pharmaceutical standards are indispensable tools for regulatory compliance, quality control, and research, ensuring that pharmaceutical products meet stringent safety and effectiveness criteria.
Subcategories of "Pharmaceutical Standards"
- APIs for research and impurities(274,905 products)
- Enzyme Activators and Inhibitors(2,827 products)
- Nitrosamines(2,605 products)
- Pharmaceutical and Veterinary Compounds and Metabolites(2,871 products)
- Toxicology(13,652 products)
Found 7836 products of "Pharmaceutical Standards"
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Vedaprofen
CAS:<p>Vedaprofen is a nonsteroidal anti-inflammatory drug that belongs to the class of drugs known as NSAIDs. It inhibits the activity of the enzyme cyclooxygenase (COX), which causes inflammation and pain. Vedaprofen has been shown to be effective in treating bowel disease, inflammatory bowel disease, and autoimmune diseases, such as arthritis. Vedaprofen also has antimicrobial properties, inhibiting bacterial growth by binding to the COX enzyme in the cell membrane. The α subunit is one of the effector proteins for COX-1 and COX-2, and vedaprofen binds to this protein preventing its activation. This inhibitory effect on COX-1 and COX-2 leads to a reduction in production of prostaglandins (PGs) that are responsible for inflammatory responses. Vedaprofen may be administered orally or intravenously depending on the severity of symptoms. The oral route is preferred because it does not require</p>Formula:C19H22O2Purity:Min. 95%Molecular weight:282.38 g/mol2,4,4’-Trichlorobiphenyl
CAS:Controlled Product<p>2,4,4’-Trichlorobiphenyl is a polychlorinated biphenyl congener. It has been shown to have an adverse effect on the central nervous system, causing neurotoxicity. 2,4,4’-Trichlorobiphenyl has been used as a model system for the study of the effects of environmental toxins on mitochondrial membrane potential and lipid peroxidation. 2,4,4’-Trichlorobiphenyl binds to fatty acids in mitochondria and inhibits fatty acid β-oxidation. The inhibition of fatty acid oxidation leads to increased levels of protocatechuic acid in the serum and liver tissue. 2,4,4’-Trichlorobiphenyl has also been found to be toxic to aquatic organisms such as fish and shrimp at low concentrations.</p>Formula:C12H7Cl3Purity:Min. 95%Molecular weight:257.54 g/mol4-Nitrophenylhydrazine hydrochloride
CAS:<p>4-Nitrophenylhydrazine hydrochloride is an organic compound that belongs to the class of hydrazines. It is a colorless solid that has a melting point of 202-204 °C. 4-Nitrophenylhydrazine hydrochloride is used in the synthesis of other compounds, such as trifluoroacetic acid and nucleophilic compounds. The chemical structure can be analyzed using nuclear magnetic resonance (NMR) spectroscopy, which shows that this compound contains amines and nitro groups. 4-Nitrophenylhydrazine hydrochloride is also soluble in water due to its acidic nature. This compound reacts with bases and alcohols to form salts, such as monosodium salt.</p>Formula:C6H7N3O2·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:189.6 g/mol7b-Hydroxy cholesterol 3b-acetate
CAS:Controlled Product7b-Hydroxy cholesterol 3b-acetate is an allylic compound that is catalyzed by molybdenum, which eliminates the acetyl group at position 7 to form a double bond with the 3-position. The reaction temperature of 7b-hydroxy cholesterol 3b-acetate can be increased to high temperatures (i.e., >100°C) for the elimination process, and allylic acetates are obtained as products. The reaction starts with the addition of hexacarbonyl, which leads to a diene intermediate. This is then eliminated by adding acetamide in presence of high concentration of acetic acid and catalytic amounts of molybdenum. The low yield and efficiency, however, are major drawbacks of this process.Formula:C29H48O3Purity:Min. 95%Molecular weight:444.69 g/molL-Aspartic acid alpha-tert-butyl ester
CAS:<p>L-Aspartic acid alpha-tert-butyl ester is a synthetic amino acid that can be used as a substrate for the synthesis of L-cysteine in the presence of selenomethionine. This compound is an auxotroph and cannot be synthesized by the body, so it must be obtained through diet or supplementation. It has been shown to have anti-cancer properties, which may be due to its role in regulating cell proliferation, apoptosis, and angiogenesis. L-Aspartic acid alpha-tert-butyl ester may also inhibit colon cancer cells by preventing them from recycling proteins. This compound was shown to inhibit HCT116 human colon cancer cells in both experimentally and computationally studies. Additionally, this molecule was seen to induce tumor regression in mice with colitis by inhibiting eukaryotic protein synthesis. This inhibition was found to be mediated through a trifluoromethyl group on the molecule's</p>Formula:C8H15NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:189.21 g/molTylosin phosphate
CAS:Controlled ProductTylosin phosphate is a macrolide antibiotic that has significant interactions with other drugs, such as erythromycin and estradiol benzoate. It is also an antimicrobial agent that can be used against human pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA). Tylosin phosphate has been shown to have toxicological studies in animals and humans, which have shown it to be chemically stable. This drug binds to fatty acids in the bacterial cell membrane, inhibiting the production of fatty acid synthase, leading to death by starvation. Tylosin phosphate may also interfere with the synthesis of phospholipids in the bacterial cell membrane and inhibit protein synthesis by binding to ribosomes.Formula:C46H80NO21PPurity:Min. 95%Color and Shape:SolidMolecular weight:1,014.1 g/molNelfinavir hydroxy-tert-butylamide
CAS:<p>Nelfinavir is an antiviral agent that is used to treat HIV/AIDS. It is a protease inhibitor that inhibits the action of the virus in cells by binding to specific enzymes, thus preventing the destruction of human cells by the virus. Nelfinavir also prevents cancer cell growth and has shown anticancer activity in animal models and humans. This drug binds to fatty acids, making it more difficult for the body to eliminate this substance. The half-life of nelfinavir is prolonged in patients with hepatic failure or renal failure. Nelfinavir can be used as a chemotherapeutic agent in infants because it does not cross the blood-brain barrier.</p>Formula:C32H45N3O5SPurity:Min. 95%Molecular weight:583.78 g/molEltrombopag olamine
CAS:Eltrombopag olamine is an orally active drug that belongs to the class of thiazolidinones. It has been used for the treatment of thrombocytopenia in patients with chronic liver disease and myelodysplastic syndrome. Eltrombopag olamine inhibits platelet aggregation by binding to glycoprotein IIb/IIIa receptors on the surface of platelets. The drug is a prodrug that is metabolized in vivo to its active form, eltrombopag. This conversion is catalysed by CYP3A4 and CYP2D6 enzymes and can be inhibited by drugs that inhibit these enzymes, such as trifluoroacetic acid and hydroxyl group-containing compounds. Eltrombopag olamine binds to erythrocytes, which may be due to its ability to form intramolecular hydrogen bonds with nitrogen atoms. The synthesis of eltFormula:C25H22N4O4•(C2H7NO)2Purity:Min. 95%Color and Shape:PowderMolecular weight:564.63 g/mol2,6-Dibromoanthracene
CAS:<p>2,6-Dibromoanthracene is an aromatic hydrocarbon that can be synthesized in a cross-coupling reaction. It has been shown to have a high electron mobility and good thermal stability. The compound was prepared by the Suzuki coupling reaction of 2,6-dibromobenzene with phenylboronic acid. This product has no commercial use but has been tested for its transport properties and has been found to be activated by heat.</p>Purity:Min. 95%N-Cbz-L-aspartic acid 1-benzyl ester
CAS:<p>N-Cbz-L-aspartic acid 1-benzyl ester is a synthetic stereoselective allyl group that can be used for biochemical studies. It has been shown to have a role in the repair of damaged DNA and cellular growth. N-Cbz-L-aspartic acid 1-benzyl ester is an adenosine diphosphate (ADP) analog, which acts as an acceptor of ADP and inhibits phosphatases.</p>Formula:C19H19NO6Purity:Min. 95%Color and Shape:PowderMolecular weight:357.36 g/molCefalexin monohydrate impurity F
CAS:<p>Please enquire for more information about Cefalexin monohydrate impurity F including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C16H17N3O4S·2H2OPurity:Min. 95%Molecular weight:383.42 g/mol5-Nitropyridin-3-ol
CAS:Please enquire for more information about 5-Nitropyridin-3-ol including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C5H4N2O3Purity:Min. 95%Molecular weight:140.1 g/mol2,6-Bis(hydroxymethyl)-p-cresol
CAS:2,6-Bis(hydroxymethyl)-p-cresol (BHMC) is a cross-linking agent that reacts with the hydroxyl groups of polymers to form covalent bonds. This reaction is irreversible and has been shown to be effective in thermal expansion applications. BHMC is insoluble in water and so can be used as a proton donor for the synthesis of polymer hydrogels. BHMC has also been used as a molecular modeling probe for studying protein structure and function. This compound reacts with nucleophiles by nucleophilic attack on the carbonyl carbon atom, producing an intermediate that tautomerizes to the corresponding enone. The reaction mechanism involves formation of a tetranuclear transition state followed by acid catalysis. Functional groups such as -OH, -NH2, or -COOH are required for this reaction to occur. NMR spectra have shown that there are three different chemical structuresFormula:C9H12O3Purity:Min. 95%Color and Shape:PowderMolecular weight:168.19 g/mol2-(4-Bromophenyl)-2,2'-dimethylacetic acid
CAS:<p>2-Bromo-2-(4-bromophenyl)-2,2'-dimethylacetic acid (2bpd) is the sodium salt of 2-(4-bromophenyl)-2,2'-dimethylacetic acid. It is a metabolite of terfenadine and thionyl chloride. 2bpd has been shown to be an inhibitor of the histamine H1 receptor. This drug is also a brominated derivative of 2-amino-2-methyl-1-propanol, which has been shown to be an inhibitor of the histamine H1 receptor.</p>Formula:C10H11BrO2Purity:Min. 95%Molecular weight:243.1 g/mol1-(3',4'-Dimethoxyphenyl)-1-propanol
CAS:1-(3’,4’-Dimethoxyphenyl)-1-propanol is a naturally occurring chemical with the molecular formula C10H14O2. It has been found in the bark of Pinus pinaster and the rhizome of Piper auritum. This compound has been shown to have an antiinflammatory effect by inhibiting prostaglandin synthesis. It also inhibits nitrosation reactions and is being studied for its potential as a cancer chemopreventive agent. 1-(3’,4’-Dimethoxyphenyl)-1-propanol is an enantiomer of 2-(3',4'-dimethoxyphenyl)propane-1,3-diol.Formula:C11H16O3Purity:Min. 95%Molecular weight:196.24 g/molProflavine hemisulfate
CAS:<p>Proflavine hemisulfate is an antibiotic that inhibits bacterial growth by binding to DNA and inhibiting DNA synthesis. It binds to the dinucleotide phosphate of the bacterial ribosome and changes the shape of the nucleotide, preventing attachment of amino acids to form proteins. Proflavine hemisulfate also has a strong affinity for nuclear dna and is bound to it in a form that inhibits replication. The free form of proflavine is converted into enzyme form by phosphorylation, which inhibits protein synthesis and cell division. Proflavine hemisulfate has been shown to inhibit multidrug efflux pumps in bacteria, leading to increased susceptibility of bacteria to antibiotics. In addition, proflavine hemisulfate possesses inhibitory properties against transfer reactions in cells. The method used for measuring proflavine hemisulfate activity is electrochemical impedance spectroscopy (EIS) on cell nuclei suspensions in a model system.</p>Formula:C13H11N3•(H2SO4)0•(H2O)xPurity:Min. 95%Color and Shape:PowderMolecular weight:258.29 g/molIsomethadone hydrochloride
CAS:Controlled Product<p>Isomethadone hydrochloride is the drug substance in a solid oral dosage form. It is an active substance that can be used to treat inflammatory diseases and target tissue. Isomethadone hydrochloride is a type of natural polymer with a metal ion as its active ingredient. The absorption mechanism for this drug is not known, but it appears to work by causing dysfunction in the membranes of cells. Isomethadone hydrochloride has been shown to cause addiction in animals and humans, and may have potential toxic effects on liver function. Symptoms of Isomethadone hydrochloride overdose include: <br>-Nausea and vomiting<br>-Constipation<br>-Loss of appetite<br>-Headache<br>-Drowsiness <br>-Confusion <br>-Muscle spasms <br>-Tremors and seizures</p>Formula:C21H28ClNOPurity:Min. 95%Molecular weight:345.91 g/mol1-Naphthalenylsulfonyl-Ile-Trp-aldehyde
CAS:<p>1-Naphthalenylsulfonyl-Ile-Trp-aldehyde is a recombinant protein that has protease activity. It is a serine protease that cleaves proteins at the amino acid sequence Ser-Xaa-Gly or Ser-Xaa. The recombinant protein has been shown to have proteolytic activity and can be used in assays to measure the amount of β-catenin, collagen, and growth factor in cells. 1-Naphthalenylsulfonyl-Ile-Trp-aldehyde also binds to monoclonal antibodies and can be used as a neutralizing agent for these proteins. This recombinant protein also has been shown to inhibit the growth of lung fibroblasts.</p>Formula:C27H29N3O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:491.6 g/mol4-Hydroxy atorvastatin disodium salt
CAS:<p>Please enquire for more information about 4-Hydroxy atorvastatin disodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C33H33FN2Na2O6Purity:Min. 95%Molecular weight:618.6 g/mol3a',4',7',7a'-Tetrahydrospiro[cyclopropane-1,8'-[2]oxa[4,7]methano[2]benzofuran]-1',3'-dione
CAS:Please enquire for more information about 3a',4',7',7a'-Tetrahydrospiro[cyclopropane-1,8'-[2]oxa[4,7]methano[2]benzofuran]-1',3'-dione including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C11H10O3Purity:Min. 95%Molecular weight:190.2 g/mol
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