Pharmaceutical Standards

Applications An impurity of Docetaxel (D494420).
References Zamir, L., et al.: Tetrahedron Lett., 33, 5173 (1992), Gueritte-Voegelein, F., et al.: J. Med. Chem., 34, 992 (1993), Volk, K., et al.: J. Chromatogr., 696, 99 (1997),

Applications 6,6'-Methylenebis(2-(tert-butyl)-4-ethylphenol) (cas# 88-24-4) is a useful research chemical.

Applications α,α,2-Trimethylcyclohexanemethanol is a volatile constituent found in leaves of Eucalyptus citriodora.
References Tian, Y., et al.: Sepu, 23, 651-54 (2005);

Applications 1-(4-(methylamino)-3-nitrophenyl)ethanone (cas# 18076-17-0) is a useful research chemical.

Applications N-[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester is an impurity in the synthesis of Gyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic.
References Mizukami, et al.: Arzneimittel-Forsch., 19, 1413 (1969); Efendic, S., et al.: Proc. Nat. Acad. Sci. USA, 76, 5901 (1979); Feldman, J.M.: Pharmacotherapry, 5, 43 (1985);

Applications 6'-Amino-1,6-dihydro-2-methyl-6-oxo[3,3'-bipyridine]-5-carbonitrile is a reagent used in the preparation of cardiotonic agents.
References Yamanaka, M. et al.: Chem. Pharm. Bull., 40, 666 (1992);

Applications (2-Fosfomycinyl-1-(hydroxy)propyl)phosphonic Acid is an impurity of Fosfomycin (F727500); an antibiotic compound used in the treatment of urinary tract infections.
References Liu, H., et al.: Zhongguo Kangshengsu Zazhi, 36, 765 (2011); Goto, M., et al.: Antimicrob. Agents Chemother., 20, 393 (1981); Keating, G. et al.: Drugs, 73, 1951 (2013); Demir, T. et al.: Int. J. Infect. Dis., 17, e966 (2013)

Applications 5-Acenaphthylenecarboxylic acid is used as additives to plastic materials.
References Bi, G., et al.: Faming Zhuanli Shenqing, 2017;

Applications Nandrolone (N315000) derivative.
References Poujol, N., et al.: J. Biol. Chem., 275, 24022

Applications 2-(Bromomethyl)-3-nitrobenzoic Acid Methyl Ester (cas# 98475-07-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Nitroethane-2,2,2-d3 (CAS# 1219802-04-6) is a useful isotopically labeled research compound.

Applications 2-[[[[1-(Methyl-d3)ethyl-1,2,2,2-d4]amino]sulfonyl]amino]-benzoic Acid Methyl Ester is an intermediate in the synthesis of Bentazon-d7 (B120583). Bentazon-d7 is deuterium labelled Bentazon (B120580), which is a herbicide.
References Ghirardello, D., et al.: Environ. Sci. Technol., 44, 9010 (2010); Frihauf, J., et al.: Weed Technol., 24, 262 (2010); Rotroff, D., et al.: Toxicol. Sci., 117, 348 (2010)

Applications Tetrachlorophthalic Anhydride is used in the synthesis of nucleoside analogues with a specific structure as apoptosis inducing active compounds. Also used in the synthesis of carbonic anhydrase inhbitors. Chlorinated Reactive Flame Retardant Intermediate
References Hirschhaeuser, C. et al.: Chem. A. Eur. J., 19, 13017 (2013); Sethi, K. et al.: Bioorg. Med. Chem., 21, 5168 (2013);

Applications Silver salt of Phosphoric Acid, used in various chemical processes as a phosphorylating compound. It is involved in the hydrolysis via phosphorylation of nanocrystals to obtain high-aspect-ratio cellulose nanocrystals. Also used in the preparation of superionic conducting glasses based upon silver halides.
References Camarero E. et al.: Biomacromol., 14, 1223 (2013); Minami, T. et al.: J. Non-Cryst. Sol., 56, 15 (1983);

Applications 4'-(Imidazol-1-yl)acetophenone (cas# 10041-06-2) is a useful research chemical.

Stability Hygroscopic
Applications 3,3',5-triiodo-β-hydroxy-D/L-thyronine is an impurity or analog of 3,3’,5-Triiodo-D-thyronine (T795375), which is a structural analogue of the thyroid hormone Thyroxine (T425600). 3,3’,5-Triiodo-D-thyronine has been shown to reduce cholesterol in blood serum.
References Mintz, D.O., et. al.: New Engl. J. Med., 266, 808 (1962)

Applications 4,4'-Diamino-2,2'-bipyridine is a bidendate chelator.

Applications Fmoc-3-(2-naphthyl)-D-alanine is an intermediate used in the preparation of phosphoserine-containing tetrapeptides with hydrophobic N-terminal acyl groups as inhibitors of the BRCA1 protein.
References Yuan, Z., et al.: Med. Chem. Lett., 2, 767 (2011); Liu, T., et al.: ACS. Comb. Sci., 13, 537 (2011);

Applications 5,6,7,8-Tetrahydronaphthalene-1-carbonyl Chloride is used in the synthesis of a sweetening agent, N-5,6,7,8-Tetrahydro-1-naphthoyl-α-L-glutamyl-5-amino-2-pyridine carbonitrile.
References Nofre, C., et al.: Eur. Pat. Appl. (1992), EP 511087 A1

Impurity Irbesartan Bromo N2-Trityl Impurity
Stability Moisture Sensitive
Applications An intermediate in the synthesis of Losartan and Valsartan.

Applications 4-Androsten-17alpha-methyl-17beta-ol-3-one-1,2-d2 is a useful isotopically labeled compound of 17α-Methyl Testosterone (M326400)

Impurity Atorvastatin lactam phenanthrene calcium salt impurity
Applications Atorvastatin (A791750) impurity. A stable Atorvastatin formulation.

Applications N-Guanyl-S-Methyl-Isothiourea Hydroiodide is a reactant used in the synthesis of novel compounds that may be used as HIV entry inhibitors.
References Wilkinson, R. et al.: Antimicrob. Agents Chemother., 55, 255 (2011);

Applications Methylamine-d5 DCl (CAS# 14779-55-6) is a useful isotopically labeled research compound.
Chemical Name: Methylamine-d5 DCl (CAS# 14779-55-6) is a useful isotopically labeled research compound.

Stability Hygroscopic
Applications A main Levomepromazine metabolite
References Hals, P., et al.: Human Toxicol., 3, 497 (1984), Cutroneo, P., et al.: J. Pharm. Biomed. Anal., 41, 333 (2006),

Applications An intermediate of Rosuvastatin (R700500).
References Laufer, S., et al.: J. Med. Chem., 45, 2733 (2002), Palani, A., et al.: Bioorg. Med. Chem. Lett., 13, 709 (2003),

Applications (±)-Carisoprodol-d7 (iso-propyl-d7) (CAS# 1218911-01-3) is a useful isotopically labeled research compound. As a deuterated drug analog, this compound can be used for inter-patient variability.
References Gant, T., et.al., U.S. Pat. Appl. Publ., 28,(2010);

Applications 2,4'-Dibromoacetophenone-2-13C (CAS# 335081-05-5) is a useful isotopically labeled research compound.

Applications 1-Acetyl-N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1h-imidazol-2-amine is a useful synthesis intermediate.