Pharmaceutical Standards

Applications An intermediate of synergistic pesticide Boscalid. Also, used in the preparation of thieno[2.3-b]pyrrole derivatives as cannabinoid receptor agonists useful in mono- and combination therapy of diseases.
References Granger, D., et al.: Arthritis Rheum., 37, 1053 (1994), Robinson, R., et al.: J. Med. Chem., 39, 10 (1996),

Applications 3'-O-Levulinoyl-N-benzoyl-2'-deoxyadenosine is a protected nucleotide derivative/building block.
References Kiuru, E., et al.: Helvetica Chimica Acta, 96, 1997-2008 (2013);

Applications [4-(Trifluoromethoxy)phenyl]carbamic Acid Methyl Ester is an intermediate in the synthesis of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.
References Luo, M., et al.: Asian. J. Chem., 24, 5148 (2012);

Applications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine (cas# 15717-45-0) is a compound useful in organic synthesis.
References Kazmers, I.S., et al.: Science, 214, 1137 (1981), Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)

Applications 2,2'-(2-Hydroxypropane-1,3-diyl)bis(1H-isoindole-1,3(2H)-dione) is a reagent used for the preparation of functionalized tripodal ligands and their metal complexes for imaging applications.
References Dunn, T.J., et al.: PCT Int. Appl., 1995:494561 (1995)

Applications Methyl 4-hydroxy-4-methyl-2-(3-nitrophenyl)-6-oxocyclohexanecarboxylate is an impurity of Nicardipine (N394500).

Applications 5-Methoxyoxazole-2-carboxylic Acid Methyl Ester,is a oxazole-containing compound, that can be extensively used in medicinal chemistry. The oxazole group is a key element of a number of biologically active natural products.
References Thalhammer, A., et al.: Tetrahedron Lett., 50, 1045 (2009);

Applications 2’-Deoxy-3’,5’-di-O-acetylguanosine reacts with hypobromous acid (HOBr) to form a major product, spiroiminodihydantoin.
References Suzuki, T., et al.: Bioorg. Med. Chem., 21, 3674-3679 (2013)

Stability Hygroscopic
Applications A 1:1 mixture of (2,4-Dinitrophenyl)hydrazine and 3,4-Dihydro-2H-pyrrole-2-carboxylic Acid.

Applications N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-2-naphthalenemethanamine-d3 hydrochloride is an labelled impurity of Terbinafine (T107500), an orally active, antimycotic allylamine and a specific inhibitor of squalene epoxidase.
References Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999);

Applications alpha-Methylene-gamma-valerolactone (cas# 62873-16-9) is a useful research chemical.