Pharmaceutical Standards

Applications Intermediate for the synthesis of 2-Hydroxymethyl Loratadine.
References Cerrada, V., et al.: ARKIVOC, 9, 200 (2005).

Applications 2',4',6'-Trihydroxyacetophenone monohydrate (cas# 249278-28-2) is a useful research chemical.

Applications N-Methyl-N-1-naphthalenylacetamide is a useful compound for organic synthesis.

Applications A 9-substituted derivative of the polycyclic aromatic hydrocarbon (PAH) Anthracene (A678400).

Applications 9-Methylanthracene-d12 (CAS# 6406-97-9) is a useful isotopically labeled research compound.

Applications 4-tert-Butyl-2-nitrophenol (cas# 3279-07-0) is a useful research chemical.

Applications N,N'-Diisopropylthiourea is a reagent for the improved synthesis of cefathiamidine. Studies on the chemical nature of the thyroid inhibiting actions of compounds. Design and testing of antithyroid agents with decreased antioxidant activity.
References Wang, H., et al.: Zhongguo Xiandai Yingyong Yaoxue, 27, 126 (2010); Astwood, E. B., et al.: Endocrinology, 37, 456 (1945); Abou-Shaaban, R. R. A., et al.: Pharm. Res., 13, 129 (1996)

Applications 2,6-Dimethylnaphthalene-d12 (CAS# 350820-12-1) is a useful isotopically labeled research compound.

Applications 1,2,3,4-Tetrahydro-1,2,8-naphthalenetriol is a reagent is used in the preparation of pharmaceuticals and in organic synthesis.

Applications 2’,3’,5’-Tri-O-benzoyl Xanthine-13C5 is an intermediate used in the synthesis of Xanthosine-13C5 (X742102), which is the labeled analogue of Xanthosine (X742100), the deamination product of Guanosine. It is also a potential biomarker for detecting radiation exposure.
References Magasanik, B, et al.: J. Bio. Chem., 206, 83 (1954);

Applications Used in the preparation of cinnamamide derivative as 5α-reductase inhibitors.
References Mai, A., et al.: J. Med. Chem., et al.: 49, 6046 (2006),

Applications Isotope labelled N-(1-Naphthyl)phthalamic Acid is an auxin-transport inhibitor in plants resulting in the attenuation of root growth through decreasing the cell production rate.
References Rahman, A. et al.: Plant, J., 50, 514 (2007); Ott, K. et al.: Phytochem., 62, 971 (2003);

Applications Benzyl 4-Nitrophenyl Carbonate is used as a reagent in the synthesis of Janus PEG-based dendrimers for use in combination therapy by controlled multi-drug loading and sequential release. Benzyl 4-Nitrophenyl Carbonate is also used as a reagent in the synthesis of Norfloxacin analogs which can exhibit antibacterial and antifungal activities under visible and UV light.
References Acton, A.L., et al.: Biomacromolecules, 14, 564 (2013); Bakhotmah, D.A., et al.: ISRN Org. Chem., 184754, 11 (2011)

Applications (5S)-5-Hydroxy-6-heptynoic Acid 1-Methylethyl Ester is an intermediate in synthesizing Resolvin E1 Sodium Salt (R144690), which is an omega-3 polyunsaturated fatty acid derivative that exhibits potent anti-inflammatory, pro-resolution, and anti-nociceptive effects. Resolvin E1 has been shown to inhibit neuropathic pain and spinal cord microgial activation following peripheral nerve injury.
References Xu, Z.Z. et al.: J. Neuroimm. Pharamcol., 2012; Schwab, J.M. et al.: Nature, 447, 869 (2007);

Applications N-[(2-Methoxyphenyl)methyl]-N,α,4-trimethylbenzeneethanamine is a new psychoactive substance that is a highly potent hallucinogen.
References Caspar, A. T., et al.: Talanta, 188, 111 (2018); Westphal, F., et al.: Drug Test. Anal., 8, 910 (2016);