Pharmaceutical Standards

Applications (4R,5R)-2,2-Dimethyl-α,α,α',α'-tetra-2-naphthalenyl-1,3-dioxolane-4,5-dimethanol, is a privileged ligand analogue of TADDOLs. It can be broadly used in asymmetric synthesis. It is also shown that the titanium TADDOLate catalysts have broad application towards carbonyl addition and cycloaddition.
References Seebach, D., et al.: Ange. Chem. Inter. Ed., 40, 92, (20010;

Applications 5,6,7-trimethyl-2,8-dihydro-1,8-naphthyridin-2-imine (cas# 69587-84-4) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 5-Aminomethyl-salicylic Acid Methyl Ester Hydrochloride (cas# 90610-24-5) is a useful research chemical.

Applications Polygalacturonic Acid is found in ripe fruits and some vegetables and is a degradation product of pectin in plants.
References Aspinall, G., et al.: J. Chem. Soc., 4020 (1958);

Applications Alpha-hydroxy-gamma-butyrolactone (cas# 19444-84-9) is a useful research chemical.

Applications Cholera Autoinducer 1: (3S)-3-Hydroxy-4-tridecanone is an extracellular quorum-sensing molecule which is responsible for the virulence production factor and biofilm development of Vibrio cholerae.
References Kelly, R. et al.: Nat. Chem. Biol., 12, 891 (2009);

Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.
References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)

Stability Hygroscopic
Applications Hematoporphyrin dihydrochlordie (cas# 17696-69-4) is a useful research chemical.

Applications 1-(4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)phenyl)ethanone is used for the synthesis of bexarotene.
References Bhirud, S.B., et al.: PCT Int. Appl. 37pp. Patent 2011 CODEN:PIXXD2

Applications 3-Hydroxy-2-naphthoic Acid-d6 is an intermediate used in the synthesis of Pamoic Acid-d10 (P173502), which is a labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency.
References Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007); Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);

Applications Perchlorate salt derivative of Adenosine (A280400), nucleotide. It is also used in the synthesis of 2’-deoxy-7-methyladenosine.
References Fujii, T. et al.: Chem. Pharm. Bull., 42, 495 (1994);

Applications N-[1-(1-Naphthalenyl)ethyl]formamide is derived from 1-Acetylnaphthalene (A186940), which is used in the preparation of S(-)-1-(1'-naphthyl) ethanol, an important synthetic intermediate of mevinic acid analog;Also, it is used in the preparation of (R)-(+)-1-(1-naphthyl)ethylamine as an intermediate of cinacalcet.
References Kamble, A.L. et al.: J. Mol. Catal. B Enzym., 35, 1 (2005); Bhattacharyya, M. et al.: Biores. Technol., 98, 1958 (2007); Xu, Y., et al.: Faming Zhuanli Shenquig (2013), CN 103420845 A 20131204

Applications (S)-(-)-Malic-2,3,3-d3 Acid (CAS# 59652-74-3) is a useful isotopically labeled research compound.

Applications 2,2'-Binaphthyl-d14 (CAS# 210487-05-1) is a useful isotopically labeled research compound.

Applications [1,1'-Biphenyl]-3,3',4,4'-tetracarboxylic acid is a useful research chemical for organic synthesis and other chemical processes.
References Wu, X., et al.: Huaxue Shiji, 39, 1015 (2017); Wang, C., et al.: J. Mol. Struct., 1080 (2015)

Applications 7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-hydroxy-2-naphthalenesulfonic Acid is an intermediate used in the synthesis of 7-[[4-[Bis(3-Amino-3-oxopropyl)amino]-6-chloro-1,3,5-triazin-2-yl]amino]-4-hydroxy-3-[(4-methoxyphenyl)azo]-2-naphthalenesulfonic Acid (B426265), which acts as a non-peptide hormone receptor antagonist affecting physiological homeostasis and reproduction. Hormone antagonist.
References Arey, B. et al.: Endocrinol., 143, 3822 (2002); Wrobel, J. et al.: Synth. Comm., 32, 2695 (2002)