Glycoscience

6-Azido-6-deoxy-1,2:3,5-bisisopropylidene-D-glycero-L-guloheptitol is a synthetic monosaccharide that can be used for the synthesis of oligosaccharides and complex carbohydrates. It is prepared by the fluorination of 6,6'-azido-1,2:3,5 bisisopropylidene D-glycero L guloheptitol. The chemical name of 6,6'-azido 1,2:3,5 bisisopropylidene D glycero L guloheptitol is 2-(6'-Amino)-2-(6'-deoxy)-1-(isopropylidene)ethanol. This compound has been shown to react with carbonyl groups in sugar molecules to form new compounds called glycosides. 6,6'-Amino 1,

NGA2F Glycan is a complex carbohydrate that is synthesized by the enzymatic transfer of an N-acetylgalactosamine (GalNAc) residue to a serine or threonine residue on protein. It is modified with methylation, Click modification, and fluorination. NGA2F Glycan has two binding sites for 2-AB labelled monosaccharides. The glycosylation site is located at the non-reducing end of the molecule, while the oligosaccharide site is located at the reducing end of the molecule.

2-Acetamido-2,6-dideoxy-D-galactose (2ADG) is a structural analogue of the natural monosaccharide 2,6-dideoxy-D-galactose. It has been shown to have an antimicrobial effect against aerobacter aerogenes in vitro. 2ADG is metabolized by glycosidases and methyl glycosides to form 1,4-anhydro-2,3,4,6 tetraacetamido-2,4,6 dideoxy D galactose. This compound inhibits the growth of bacterial strains that are resistant to polymyxin b., such as Pseudomonas aeruginosa. The inhibition of these bacteria is due to the inhibition of the synthesis of their outer membrane lipopolysaccharides by 2ADG. The antibacterial activity is also attributed to its ability to inhibit the metabolism of glycan molecules in some bacteria

Glycosylation of azetidinol is a chemical reaction in which a glycosylate group is transferred from an activated sugar to the nitrogen atom of an azetidinone. It can be used for the synthesis of oligosaccharides and polysaccharides by transferring the glycosyl group to their nitrogen atoms. Click modification refers to a type of chemical reaction that was developed by K. Barry Sharpless in 1996, which uses copper-catalyzed azide-alkyne cycloaddition. This type of reaction has been used for the synthesis of complex carbohydrates with high purity and low cost, as well as for modifying sugars with methyl groups or fluorine atoms.

Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant

6- Deoxy- 1, 2:3, 5- bis- isopropylidene-D- ido-heptitol is a modified oligosaccharide that is used as a reagent in the synthesis of complex carbohydrates. It has been shown to inhibit bacterial growth by binding to ribose and other sugars. 6-Deoxy-1,2:3,5-bis-isopropylidene-D-idoheptitol can be used to produce glycosides or methylated saccharides. This compound has been shown to have high purity and the CAS number for this product is 107738-94 -7.

Methyl β-L-arabinopyranoside is a stereochemically pure monosaccharide that has been used to calibrate and quantify the conformational, stereochemical, and spectrometric methods. Methyl β-L-arabinopyranoside has a conformation that is restricted by the presence of an α-hydroxyl group at C2. The chloride ion can be used to monitor this conformation. The diameter of methyl β-L-arabinopyranoside can be measured with a micropipette and monitored using an aerosol detector. Methyl β-L-arabinopyranoside can also be quantified by mass spectrometry or spectrophotometry. The conformational, stereochemical, and spectrometric methods have been calibrated using methyl β-L-arabinopyranoside as a standard to determine their accuracy in measuring the size of other molecules.

Propylene glycol alginate is a reaction product of propylene oxide and alginic acid. At the 49th JECFA meeting (1997) it was resolved that the total dietary propylene glycol intake from all sources should be allocated an ADI of 0-25 mg/kg.  Applications include as a stabiliser in beer foam due to electrostatic interaction between carboxyl groups on the glycol alginate molecules and amino groups on the peptides in the bubble wall and in ice cream by emulsifying the fat.Esterification is greater then 80%Viscosity (1% aq solution): 200-300 mpa.s

N-Acetyl-D-galactosamine-6-O-sulphate sodium is a carbohydrate that is used in the synthesis of oligosaccharides. The saccharide is fluorinated, methylated, and glycosylated. It also has a click modification at the reducing end. N-Acetyl-D-galactosamine-6-O-sulphate sodium is synthesized by custom synthesis and has high purity.

Heparin is a glycosaminoglycan which occurs in many mammalian tissues and has important anticoagulant and thrombolytic properties. The chemical structure is composed mainly of two disaccharide repeating units A and B. A is L-iduronic acid 2-suplhate linked α-(1,4) to 2-deoxy-2-sulfamido-D-galactose 6-sulphate while B is D-glucuronic acid β-(1,4) linked to 2-deoxy-2-sulfamido-D-glucose 6-sulphate.