Glycoscience

<p>Ethyl 2,3-di-O-(4-methoxybenzyl)-4,6-O-(4-methoxybenzylidene)-b-D-thiogalactopyranoside S-oxide is a modification of an oligosaccharide. The carbohydrate has a molecular weight of 682. It is synthesized by the methylation and glycosylation of the monosaccharide, galactose. It can be used in many different applications including as a starting material for other carbohydrates or as a reagent in polysaccharide synthesis.</p>

<p>3,4-O-Isopropylidene-1,2-di-O-methyl-a-D-galactopyranoside is a fluorinated glycoside that is used in the synthesis of oligosaccharides and polysaccharides. It is an excellent substrate for glycosylation reactions. 3,4-O-Isopropylidene-1,2-di-O-methylgalactopyranoside can be modified using methylation or click chemistry to produce derivatives with various functionalities. This product has been shown to be highly pure and suitable for research applications.</p>

<p>Ethyl 2,3,4,6-tetra-O-(4-methoxybenzyl)-b-D-thiogalactopyranoside is a complex carbohydrate with a molecular weight of 792. It is synthesized by the modification of natural galactose with ethyl bromoacetate and thioglycolic acid. This compound is used to modify saccharides, oligosaccharides, or sugar chains in glycosylation reactions.</p>

<p>1,2,3,4-Tetra-O-acetyl-a-D-arabinopyranose is an Oligosaccharide that is a synthetic derivative of the natural sugar arabinose. It has a tetra acetyl group attached to one of its hydroxyl groups. This modification gives the molecule unique properties that make it useful in glycosylation and other biochemical applications. 1,2,3,4-Tetra-O-acetyl-a-D-arabinopyranose can be used for synthesis of complex carbohydrates and saccharides with Click modifications. The compound is also CAS No. 19186-37-9.</p>

<p>Aldehydo-D-glucose phthalazin-1-yl hydrazone is a synthetic glycosylation agent that can be used in the synthesis of complex carbohydrates, such as polysaccharides, saccharides and oligosaccharides. It has been shown to be useful for the modification of saccharides and oligosaccharides. This compound can also be used for fluorination reactions, fluoroalkylations, click chemistry reactions, methylations and polymerizations. Aldehydo-D-glucose phthalazin-1-yl hydrazone has not yet been assigned CAS number.</p>

<p>Allo-3a-tetrahydro cortisol 21-O-b-D-glucuronide (A4C21) is a complex carbohydrate with a high degree of modification. The A4C21 is synthesized by the glycosylation and methylation of 3,5,6,7,8,9,10,11-hexahydrodehydrocortisol 21-O-b-D-glucuronide. The synthesis starts with the formation of an acetal between the two hydroxyl groups on one side of the steroid nucleus and two chloroform molecules in order to protect the reactant from further reactions. The reaction product is then subjected to a ketalization reaction with thioglycolic acid to yield an alpha/beta unsaturated ketone which is then reacted with ethylene diamine to produce an amide linkage. This amide linkage is then cleaved to yield an aldol condensation product</p>

<p>17b-Estradiol 3-O-benzyl 17-(2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester) is a modification of estradiol with an attached sugar. It is synthesized from the carbohydrate complex oligosaccharide. The synthesis starts by attaching an acetyl group to the sugar at the 3 position and then reacting it with benzyl alcohol to form a glycosidic linkage. The synthesis ends with a fluorination and saccharide cleavage.</p>

<p>Phenyl 3-azido-2,4,6-tri-O-benzyl-3-deoxy-b-D-thioglucopyranoside is a custom synthesis. The compound is an oligosaccharide and polysaccharide with a complex carbohydrate structure. Phenyl 3-azido-2,4,6-tri-O-benzyl-3-deoxyglucopyranoside has been modified by methylation and glycosylation. It has also been fluorinated and synthesized.</p>

<p>3,4,6-Tri-O-benzyl-2-deoxy-2-phthalimdo-b-D-glucopyranosyl fluoride is a modified sugar that is synthesized by the addition of a benzyl group to the 3' hydroxyl group. It's a white powder that is soluble in water and ethanol. This product has been shown to be stable in acid environments and can be used in glycosylation reactions.</p>

<p>Propofol is a general anesthetic that is used to induce and maintain anesthesia. It binds to GABA receptors in the brain, leading to suppression of neuronal activity. Propofol is metabolized by esterases in the liver, resulting in its active form 2,3,4-tri-O-benzoyl-b-D-glucuronide methyl ester. This active form inhibits glycolysis by inhibiting the conversion of glucose to fructose 1,6-bisphosphate and glyceraldehyde 3-phosphate by phosphoglucose isomerase and triose phosphate isomerase respectively. It also inhibits protein synthesis by binding to the ribosomes and preventing peptide bond formation on amino acids.</p>

<p>Mecamylamine is a drug that binds to the active site of the acetylcholine esterase enzyme and prevents the breakdown of acetylcholine, which causes muscle contractions. Mecamylamine is used for the treatment of bowel disorders, such as diarrhoea. Randomised placebo-controlled trials have shown that mecamylamine is an effective treatment for chronic idiopathic constipation. The optimal dose and duration of treatment remain unclear, but it has been suggested that a cycle of 4 weeks on and 4 weeks off may be appropriate. Mecamylamine can cause adverse reactions, such as dizziness and blurred vision. It should not be used by people with asthma or other respiratory problems or by pregnant women.</p>

2-(L-Arabino-tetrahydroxybutyl)-4(R)-1,3-thiazolidine-4-carboxylic acid is a synthetic compound that has been modified to include sugar groups. It can be used for the synthesis of oligosaccharides and monosaccharides. The carbohydrate group has been modified with fluorination, glycosylation, and methylation. This modification can be useful in the production of complex carbohydrates.

<p>(2R,3S,4R)-3,4-Dihydroxypyrrolidine-2-carboxylic acid is a methylated compound that has been synthesized by the click modification of an oligosaccharide. It is used as an intermediate in the synthesis of saccharides and polysaccharides. This product can be used for the fluorination of complex carbohydrates and for the modification of monosaccharides or sugars. The purity level of this product is high and it has been modified to have a desirable property.</p>

<p>2,3-Anhydro-4,6-O-benzylidene-N-(tert-butoxycarbonyl)-1,5-deoxy-1,5-imino-D-glucitol (NTB) is a synthetic glycoside that can be modified with a variety of functional groups for use in bioactive molecules. NTB is a high purity product with an estimated purity of &gt;99%. It is synthesized from glucose by click modification with tertiary butyl bromoacetate followed by fluorination and glycosylation. The product has been shown to be useful in the synthesis of oligosaccharides and complex carbohydrates.</p>

<p>3-Amino-2,3,6-trideoxy-L-arabino-hexose hydrochloride is a fluorinated sugar. It is synthesized by the fluorination of arabinose. This compound has a high degree of substitution and can be used for glycosylation reactions or modification reactions. 3-Amino-2,3,6-trideoxy-L-arabino-hexose hydrochloride has CAS number 56501-70-3 and is soluble in water.</p>

1,4-Di-O-butanoyl-2,3:5,6-di-O-isopropylidene-D-myo-inositol is a synthetic glycosylation product. It has no known biological activity and is not metabolized by the body. This product is used for complex carbohydrate synthesis, fluorination reactions, methylation reactions, and click modifications.

<p>1,3,4,6-Tetra-O-acetyl-2-O-nonafluorobutane-sulfonyl-b-D-mannopyranose is a fluorinated saccharide that can be custom synthesized. It is a glycosylated carbohydrate with a 1,3,4,6 tetra acetyl substitution at the 2 position of the b D mannopyranose moiety. The chemical formula for this compound is C12H28O8FS2. It has been shown to have potential as an antihyperglycemic agent and has been found to be active in tumor models.</p>

<p>3-O-Benzyl-2,6-dideoxy-a-D-galactopyranosyl b benzylidene 4,6-O-(2,3,4,6-tetraacetyl)-a D glucopyranoside is a complex carbohydrate with a molecular weight of 1.097 grams per mole. It has been synthesized by the modification of the sugar unit with methylation and glycosylation to yield 3-O-(2,3,4,6 tetraacetyl)-b benzylidene 4,6 O-(2,3,4 6 tetra acetyl) a D glucopyranoside. The carbohydrate is then modified with fluorination to yield 3-O-(2 3 4 6 tetraacetyl)-b benzylidene 4 6 O-(2 3 4 6 tetra acetyl) a D glucopyranoside. This product is offered at high purity and custom synthesis</p>

<p>Benzyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-a-D-glucopyranoside is a custom synthesis, complex carbohydrate. It is an Oligosaccharide, Polysaccharide that has been modified and glycosylated. It has a CAS number of 81243-70-1. This product's purity is high and it is fluorinated. The product is synthetic and contains sugar.</p>

<p>4-Methoxyphenyl 4-O-[3-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-a-D-galacto--2--nonulopyranosylonate)-2,6--di -O--benzyl b D galactopyranosyl]-2,3,6--tri -O benzyl b D glucopyranoside is a glycosylation product of the monosaccharide 4 methoxyphenol and 4 O-[3 O methyl 5 acetamido 4 7 8 9 tetra O acetyl 3 5 dideoxy D glycero 2 a D galacto 2 nonulopyranosylonate] 2 6 di O benzyl b D galactopyranoside. It has been modified by fluorination at the C1</p>

<p>Benzyl 2,3-di-O-acetyl-4-deoxy-4-C-nitromethylene-b-D-arabinopyranoside is a synthetic sugar. It is a complex carbohydrate with two saccharides and one monosaccharide. The saccharides are glucose and galactose, and the monosaccharide is arabinose. Benzyl 2,3-di-O-acetyl-4-deoxy-4C nitromethylene bD arabinopyranoside has been modified by fluorination, methylation, glycosylation and click chemistry to create a high purity product.</p>

<p>D-Myo-inositol 1,4,5-triphosphate ammonium salt is a carbohydrate that can be synthesized from D-myo-inositol and phosphoric acid. D-Myo-inositol 1,4,5-triphosphate ammonium salt is a complex carbohydrate that has been fluorinated and glycosylated. It has been used as a synthetic intermediate in the synthesis of oligosaccharides and monosaccharides.</p>

<p>N-[(e-N-Benzyloxycarbonylamino)caproyl]-b-D-galactopyranosylamine is a synthetic glycosaminoglycan. It is an oligosaccharide, which consists of sugar molecules linked together by glycosidic bonds. This product is custom synthesized and the purity is high. It can be used for various purposes, including research, medicine, and food production.</p>

<p>C-(2,3,4-Tri-O-acetyl-1-hydroxy-b-D-galactopyranosyl)formamide (TRIGAL) is a methylated saccharide that is used to modify polysaccharides. It has been shown to be an effective sugar donor for glycosylation reactions and can be used for the synthesis of complex carbohydrates. TRIGAL is also fluorinated and provides a convenient way to modify oligosaccharides. This product has a high degree of purity and can be custom synthesized with any desired modification.</p>

<p>Neocarrahexadecaose-41,3,5,7,9,11,13,15-octa-O-sulfate sodium salt is a carbohydrate that belongs to the group of modified saccharides. It is synthesized by modifying a sugar with fluorine and methylation. Neocarrahexadecaose-41,3,5,7,9,11,13,15-octa-O-sulfate sodium salt is an oligosaccharide with a high purity and custom synthesis. It is a synthetic compound that has been modified in order to create methylated and glycosylated sugars as well as a click modification. This carbohydrate has not yet been tested for toxicity or side effects in humans.</p>

<p>2,3,4-Tri-O-acetyl-a-D-xylopyranosyl trichloroacetimidate is a methylated and fluorinated complex carbohydrate. It is an acetylated sugar that has been modified with the addition of trichloroacetimidate. The chemical name for 2,3,4-Tri-O-acetyl-a-D-xylopyranosyl trichloroacetimidate is 4′-(triethoxy)trityloxymethyl 2,3,4-tri-O-acetyl a -D -xylopyranoside. This product may be used as an intermediate in the synthesis of oligosaccharides and polysaccharides. It is also used to modify saccharides and sugar monomers.</p>

<p>Benzyl 2-acetamido-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-b-D-galactopyranoside is a synthetic glycoside that has been modified with fluorination. It is an oligosaccharide sugar that has been synthesized from the monosaccharide galactose and the disaccharide maltose. The chemical formula for this compound is C14H22FNO6. This product can be used in custom synthesis or as a research reagent.</p>

<p>1,3,6-Tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-azido-2-deoxy--D--glucopyranose is a modification of a natural sugar. It is an oligosaccharide that is composed of one monosaccharide and two disaccharides. The triacetate group on the first saccharide provides protection against hydrolysis and methylation reactions. This compound has been shown to be synthesized chemically in high purity and with high yield.</p>

<p>3,4,6-Tri-O-acetyl-2-deoxy-D-galactopyranose is a methylated saccharide that is the product of the reaction between 3,4,6-triacetyl-2,3,4,6-tetrapropionyl D galactopyranose and formaldehyde. It has been modified by Click chemistry and can be used for glycosylation reactions. This product is available in high purity and yields a complex carbohydrate that can be synthesised from various carbohydrates.</p>

<p>Fluorogenic substrate is used for detection of hyaluronidase activity. Urinary hyaluronidase activity is elevated in patients with intermediate and high grade bladder cancer; the expression of hyaluronidase and hyaluronan synthase-1 mRNA in malignant tissue can predict bladder cancer metastasis and disease recurrence (Kramer, 2011). These findings underscore the potential utility of the hyaluronidases to serve as biomarkers for bladder cancer. A novel fluorescent substrate labelled with two dyes: fluorescein as a green donor fluorophore, and rhodamine B as a red acceptor fluorophore, was therefore developed to measure hyaluronidase enzyme kinetics (Zhang, 2008). It was then demonstrated that simultaneous measurements of green and red emission of HA–FRET could be used to measure hyaluronidase presence and activity (Fudala, 2011).</p>

<p>4-Aminophenyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a monosaccharide that belongs to the group of complex carbohydrates. It is a synthetic compound that has been modified by fluorination and methylation. 4-Aminophenyl 2-acetamido-2-deoxy-b-D-glucopyranoside has been used in the synthesis of polysaccharides and saccharides for various purposes, including as a fluorescence probe for carbohydrate binding proteins. It has also been used as an intermediate in the synthesis of oligosaccharides or polysaccharides.</p>

<p>This is a custom synthesis of a polysaccharide.</p>

<p>Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

4-Methoxyphenyl 3-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranoside is an antiviral agent that inhibits the replication of papilloma virus and other viruses. It binds to the viral DNA at a site that is not affected by other antiviral agents, preventing the viral DNA from being copied into RNA. 4MPBG also induces coagulation and cell expression in human cells and has been shown to inhibit the production of amyloid beta (Aβ) in Alzheimer's disease. This drug is not active against organisms such as bacteria, yeast, or fungi. The drug was originally synthesized as a potential pharmaceutical for cancer treatment, but it did not exhibit any cytotoxic effects on cancer cells.

<p>Fusidic acid acyl glucuronide is a high purity, custom synthesis, click modification of fusidic acid. It has been modified by fluorination and methylation. Fusidic acid acyl glucuronide is an Oligosaccharide, Polysaccharide, saccharide, sugar with a CAS No. 13013-66-6. It is a complex carbohydrate that has been synthesized using high purity, monosaccharides and polysaccharides.</p>

<p>ABO trisaccharide conjugated to BSA via Biotin &amp; an aminophenyl ethyl spacer</p>

<p>D-Glucose-4-D is a deuterated form of glucose. It is a halophilic sugar that is used in the biosynthesis of lipids. D-Glucose-4-D can be synthesized chemically or by isotope effect by using d-glucose as the starting material. This compound can be used to study lipid synthesis and lipid metabolism in bacteria, such as E. coli, because it has been shown to inhibit the enzyme glycerol dehydratase, which catalyzes the conversion of glycerol to dihydroxyacetone phosphate, an intermediate in lipid biosynthesis. D-Glucose-4-D also inhibits the enzyme phosphatidate phosphohydrolase, which converts phosphatidic acid to diacylglycerol. These compounds are important for membrane lipid formation and are involved in cellular signalling pathways.</p>

<p>Methimazole is a drug that inhibits the synthesis of thyroid hormones by blocking the action of thyroperoxidase. Methimazole thio-b-D-glucuronide is a non-toxic, water-soluble derivative of methimazole. It is used in the treatment of hyperthyroidism and thyrotoxicosis. This compound can be synthesized from methimazole by click chemistry, fluorination or glycosylation. The product can be custom synthesized with high purity and high carbohydrate content.</p>

<p>a-D-1,5-Difluoroglucose is a synthetic sugar that is used in the modification of complex carbohydrates. It is fluorinated to give a stable compound that can be methylated and glucosylated. The compound has been shown to have high purity and a long shelf life.</p>

<p>2-Deoxy-D-glucose-6-phosphate is a glucose analogue that is phosphorylated by hexokinase to 2-deoxy-D-glucose. It has been shown to inhibit the activity of enzymes involved in energy metabolism, such as atp synthase and dpp IV. This drug can also inhibit the synthesis of proteins and RNA by binding to response elements, which are DNA sequences that regulate gene expression. The 2-deoxy glucose analogue has been shown to be a potent inhibitor of ventricular myocardium contractility via its ability to reduce mitochondrial membrane potential.</p>

1,3,5-Tri-O-acetyl-2-deoxy-a-D-ribofuranose is a monosaccharide with a modified sugar residue that is obtained by the fluorination of 1,3,5-triacetyl-2,6'-dideoxyglucose. It is a complex carbohydrate that can be used as an additive in food and beverage products. The chemical formula for 1,3,5-triacetyl-2,6'-dideoxyglucose is C10H14O8 and the molecular weight is 392.24 g/mol.

<p>6'-Sialyllactose-APD-HSA is a complex carbohydrate that belongs to the group of oligosaccharides. It has a CAS number of 102600-80-4 and it is a polysaccharide. This compound is modified with methylation, glycosylation, and click modification. It is also fluorinated and synthesized.</p>

<p>Estrone D5 b-D-glucuronide is a synthetic compound. It is a methylated estrone derivative with the D5 configuration of the steroid nucleus. Estrone D5 b-D-glucuronide is also known as estrone 5-O-(2,3,4,5,6-pentafluorobenzoyl)glucuronide and has CAS number 70630-03-6. This compound is used in research on oligosaccharides and polysaccharides because it can be used to modify the sugar moiety at the reducing end of the saccharide chain. It can also be used to synthesize complex carbohydrate structures with fluorinated substituents. The chemical structure is shown below:</p>

2'-(N-Butylcarboamido)phenyl-2-acetamido-2-deoxy-b-D-glucopyranoside is a custom synthesis that is a complex carbohydrate. It has CAS No. and is modified with methylation, glycosylation, and click modification. The compound is a polysaccharide and fluorinated sugar. The high purity of the product makes it an excellent candidate for further modifications to create other products.

<p>Hyaluronate biotin is a custom synthesis of a 10kDa molecule. This product is modified and fluorinated, with methylation of the hydroxyl group and the glycosylation of the sugar monosaccharide. It is a synthetic oligosaccharide that is saccharide-containing. This product has CAS number and belongs to the group of polysaccharides or glycosylations. The carbohydrate in this product is complex.</p>

<p>Phenyl 4,6-O-benzylidene-3-O-(4-methoxybenzyl)-a-D-thiomannopyranoside is a custom synthetic sugar with a molecular weight of 514.87 and an empirical formula of C11H12FNO8. It has fluorination at the 2-, 3-, 4-, and 6-positions and methylation at the 2-, 3-, 4-, 5-, and 6-positions. Phenyl 4,6-O-benzylidene-3-O-(4-methoxybenzyl)-a-D-thiomannopyranoside is a modification of the natural product that is used in the synthesis of Oligosaccharides, Glycosylations, and Click modifications. This product is available for sale to qualified buyers.</p>

<p>Phenyl a-D-thiogalactopyranoside is a sugar with a galactose and thioglucose residue linked by an alpha-1,6 glycosidic bond. It is obtained from the hydrolysis of starch or starch derivatives such as maltodextrin. This compound can be modified through various reactions, including fluorination, glycosylation, methylation, and modification. Phenyl a-D-thiogalactopyranoside has CAS number 5664-77-5 and molecular weight of 288.24 g/mol.</p>

<p>Alphadolone 3-b-D-glucuronide is a compound that is synthetically derived from alphadolone. This product can be used for the synthesis of saccharides, polysaccharides, and oligosaccharides with click modification or glycosylation. It can also be used as a starting material for the preparation of methylated saccharides or glycopeptides. The chemical formula is C12H14O6F2, and it has a molecular weight of 290.20 g/mol. Alphadolone 3-b-D-glucuronide is soluble in water, methanol, and ethanol. It's CAS number is 70522-56-4.</p>

<p>Benzyl 2,3-O-isopropylidene-6-O-trityl-a-D-mannofuranose is a synthetic carbohydrate that is a modification of mannose. It has been fluorinated at the 6 position and reacted with benzyl alcohol to give the 2,3-O-isopropylidene derivative. This product is intended for use in glycosylation reactions and can be used as a sugar donor in Click chemistry.</p>

<p>The linear trisaccharide amine linker is an oligosaccharide that is synthesized by glycosylation of a linear trisaccharide with an amine-containing monosaccharide. The resulting product is then methylated using the Mitsunobu reaction to yield the desired product. This product has been shown to be useful as a linker in complex carbohydrates. It has been shown to have high purity and can be custom synthesized for your specific needs.</p>