Glycoscience

<p>1-Deoxy-1-nitro-L-galactitol is a compound that has been shown to inhibit serine protease and glutaminyl cyclase activity. It is commonly used in laboratory settings as a potassium substitute in media formulations. This compound belongs to the class of monosaccharides known as glutaminyl derivatives. It has been studied for its potential as an inhibitor of nafamostat, a serine protease inhibitor used in the treatment of pancreatitis and disseminated intravascular coagulation (DIC). Additionally, 1-Deoxy-1-nitro-L-galactitol has been investigated for its potential as a disinfectant and as an adrenergic receptor agonist. Preliminary studies have also suggested antiviral properties against certain viruses. Further research is needed to fully understand the potential applications of this compound.</p>

<p>2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-b-D-glucopyranose is a synthetic sugar that is used as a glycosylate building block in the synthesis of oligosaccharides and polysaccharides. This product can be fluorinated at either the 2 or 5 position to provide a variety of reactive functionalities. It can also be modified with methyl groups to produce an NMR substrate for the study of sugar metabolism.</p>

<p>3-O-tert-Butyldimethylsilyl-D-galactal is a synthetic, fluorinated monosaccharide that has been used as a substrate for glycosylation reactions. The compound is synthesized by the reaction of 3,4,6-trichloro-2,5,7,8-tetrafluorohexanal with D-galactal in the presence of a base such as potassium carbonate. The product is purified by column chromatography and recrystallization from methanol to provide a white powder with a melting point of 176 °C.</p>

<p>4-Methoxyphenyl 3-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonate)-2,6 -di--Obenzyl b--D--galactopyranoside is a synthetic carbohydrate. This compound has been custom synthesized for research purposes. The chemical structure of this compound is a methylated oligosaccharide with the following modifications: click modification and fluorination.</p>

<p>Maltohexaose is a polysaccharide formed by 6 units of glucose and can be metabolised inside the cell to a substrate-based inhibitor of fucosyltransferases. It can also be converted to GDP-2-deoxy-2-fluoro-L-fucose, a competitive inhibitor of α-1,3-fucosyltransferase. Matohexaose is used as acceptor for measuring the activity of 4-Alpha-Glucanotransferase.</p>

<p>The antibiotic 2-deoxy-3,4:5,6-di-O-isopropylidene-D-arabino-hexose propane-1,3-diyl dithioacetal is a shikimate analog that inhibits the shikimate pathway. It prevents the synthesis of aromatic compounds and other nitrogenous substances by inhibiting the enzyme chorismate synthase. Chorismate synthase catalyzes the conversion of 3,4:5,6-di-O-isopropylidene D-arabino hexose to chorismic acid which is then converted to shikimic acid. The antibiotic binds covalently to an active site cysteine residue on the enzyme and inhibits its activity. This inhibition blocks the production of aromatic amino acids and other nitrogenous substances required for protein synthesis in bacteria.</p>

<p>The maltose solution we offer is a 20% solution in water and of high purity and can be customized to meet your needs.</p>

<p>Methyl 3-acetamido-4-O-benzoyl-6-bromo-2,3,6-trideoxy--aDribohexopyranoside is a Custom synthesis that is classified as an Oligosaccharide. It has a molecular weight of 576.07 and a purity of &gt;99%. The chemical formula for this compound is C22H30BrNO8. Methyl 3-acetamido-4-O-benzoyl-6-bromo-2,3,6--trideoxy--aDribohexopyranoside is used in the modification of saccharides with the purpose of synthesizing polysaccharides. This compound has been shown to be effective for the synthesis of glycosylations and methylations.<br>Methyl 3 acetamido 4 O benzoyl 6 bromo 2,3,6 trideoxy - a D rib</p>

<p>Phenylephrine-D-glucuronide is a modified form of phenylephrine that is synthesized from the natural product glycosylate. It has been shown to have a high degree of purity and is custom synthesized for customers. This compound can be modified in many ways, including fluorination, glycosylation, methylation, and saccharide modification. Phenylephrine-D-glucuronide has the ability to bind to sugar molecules and form complex carbohydrates. Phenylephrine-D-glucuronide is also an oligosaccharide or monosaccharide with a saccharide backbone.</p>

<p>1-Deoxy-L-idonojirimycin hydrochloride is a chaperone that is structurally related to the natural substrate, L-idonojirimycin. It has been found to interact with recombinant human Hsp70 and Hsp90. 1-Deoxy-L-idonojirimycin hydrochloride enhances the kinetic and thermodynamic parameters of these chaperones in vitro. The structural analysis of this compound revealed that it binds to both Hsp70 and Hsp90, which may be due to its ability to mimic the natural substrate's binding site on these chaperones.</p>

<p>Quinovic acid 3-O-b-D-glucoside is a fluorinated saccharide that has been synthesized in the laboratory. It is a high purity, synthetic sugar with an M+1 ion at m/z 571. The structure of this compound is O-α-D-mannopyranosyl-(1→2)-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-O-.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-acetyl-4-O-[2,4,6-tri-O-acetyl-3-O-(3,4,6-tri-O-acetyl-2-deoxy-2 -phthalimido)-bDglucopyranosyl]-bDgalactopyranoside is a high purity methylated glycoside of 4 methoxyphenol. The product has been modified by fluorination and Click chemistry to produce a complex carbohydrate. This modification can be used for the synthesis of oligosaccharides and polysaccharides.</p>

<p>1,6:3,4-Bis-[O-(2,3-dimethoxybutane-2,3-diyl)]-2-O-trifluoromethanesulphonyl-5-O-benzolyl-myo-inositol is a Glycosylation product with CAS No. 1068089-34-8. It is a synthetic oligosaccharide that contains an Oligosaccharide sugar and a Polysaccharide saccharide. The product has been Fluorinated and Custom synthesized for Methylation. Click modification has been performed on the complex carbohydrate to produce the desired Modification in High purity.</p>

<p>N-Acetylserotonin β-D-glucuronide is a metabolite of melatonin, which is synthesized in the pineal gland. It is excreted in human urine and can be used as a biomarker for melatonin synthesis. N-Acetylserotonin β-D-glucuronide has been shown to have pharmacologic effects on humans and other species, but its health effects are not well understood. The use of this compound as a biomarker for human melatonin synthesis has been validated in vitro and in vivo. It is also used as a marker for kidney function, particularly chronic kidney disease (CKD). This analysis can be performed using urinary samples that contain glucuronide conjugates of N-acetylserotonin β-D-glucuronide.</p>

<p>Sennoside D is a fatty acid that can be isolated from the sennosides found in the leaves of the plant Senna alata. It has been shown to have anti-tumor properties and may play a role in treating colon cancer, breast cancer, and skin cancer. Sennoside D has also been shown to be effective against autoimmune diseases such as arthritis, ulcerative colitis, and Crohn's disease. The low energy of this compound may be due to its formation rate. The hydroxide solution (NaOH) is used in the synthesis of this molecule because it binds with carbon dioxide molecules to form sodium bicarbonate and carbon dioxide gas which can then be captured by water. This process produces a high yield of sennoside D. In addition, the bound form of this molecule is soluble in organic solvents and insoluble in water, which makes it suitable for skin conditions as well as colon cancer treatments.</p>

<p>The characteristic structure of pectin is a linear chain of α-(1,4)-linked D-galacturonic acid that forms the pectin-backbone, a homogalacturonan (pectic acid). The polygalacturonic acid is partly esterified with methyl groups and the free acid groups may be partly or fully neutralized with sodium, potassium or ammonium ions. The ratio of esterified galacturonic acid groups to total galacturonic acid groups - termed the degree of esterification (DE) - has vital influence on the properties of pectin, especially the solubility and the gel forming characteristics. The mechanism for gel formation with calcium ions is known as ‘The egg box’. Into this backbone, there are regions where galacturonic acid is replaced by (1,2)-linked L-rhamnose. From the rhamnose residues, sidechains of various neutral sugars branch off. This type of pectin is called rhamnogalacturonan-I (RG-I). Up to every 25th galacturonic acid in the main chain is replaced with rhamnose. Some stretches consist of alternating galacturonic acid and rhamnose – “hairy regions”, others with lower density of rhamnose – “smooth regions”. The neutral sugars are mainly D-galactose, L-arabinose and D-xylose, the types and proportions of neutral sugars varying with the origin of pectin. Another structural type of pectin is rhamnogalacturonan II (RG-II), which is a less frequent complex, highly branched polysaccharide.</p>

<p>Ethyl D-thioglucuronide is a modification of an oligosaccharide, carbohydrate, complex carbohydrate or sugar. It can be synthesized by custom synthesis or by synthetic methods. The product is highly pure and monosaccharide methylated. The product can be glycosylated, polysaccharide, sugar fluorinated and saccharides click modified.</p>

<p>Phenyl b-D-thiogalactopyranoside is a carbohydrate binding agent that has been shown to have anti-cancer properties. It binds to galectin, a carbohydrate receptor on the surface of tumour cells, thereby interfering with cell proliferation and tumor growth. Phenyl b-D-thiogalactopyranoside also blocks the activity of glycolytic enzymes and can be used as an adjuvant in cancer therapy. This molecule is synthesized by nature or chemically by means of alkylation of phenol. The chemical synthesis is more efficient and economical than the natural process.</p>

<p>Dihydroresveratrol 3-O-glucoside is a synthetic, monosaccharide, oligosaccharide, complex carbohydrate with the molecular formula C6H10O5. It has CAS No. 100432-87-9 and is custom synthesized. Dihydroresveratrol 3-O-glucoside is glycosylated and polysaccharided with a high purity.</p>

<p>L-Noviose is a glycopeptide antibiotic that has been modified to increase its stability and bioavailability. The modifications have led to an increase in the activity of L-Noviose against gram-negative bacteria, including strains resistant to other antibiotics. This drug also inhibits bacterial biosynthesis by binding to the 30S ribosomal subunit and preventing the initiation of protein synthesis. L-Noviose is used clinically for the treatment of infections caused by Actinomyces, Enterobacter, Erysipelothrix, Haemophilus, Klebsiella, Proteus mirabilis, Pseudomonas aeruginosa and Staphylococcus aureus. The biological function of L-Noviose is to inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit.</p>

<p>2-Azido-4,6-O-benzylidene-N-Boc-1,2,5-trideoxy-1,5-imino-D-glucitol is a synthetic carbohydrate that has been modified with fluorine. The modification has been shown to have an inhibitory effect on the growth of cancer cells. 2-Azido-4,6-O-benzylidene can be used for the synthesis of glycosides and polysaccharides. It can also be used as a click modification agent for proteins.</p>

<p>D-Ribose-2-D is a modified D-ribose sugar. It is an oligosaccharide that is a component of polysaccharides and glycosaminoglycans. The modification of this sugar includes methylation, glycosylation, and fluorination. This product has CAS No. 202480-69-1 and is synthesized in high purity with 98% purity.</p>

<p>1-Bromo-2,3,4-tri-O-benzoyl-a-D-glucuronide methyl ester is a custom synthesis. It is a high purity product with a custom synthesis. The CAS No. for this compound is 103674-69-7. This product undergoes Click modification and has high purity. The sugar in this compound is an oligosaccharide with glycosylation.</p>

<p>3,4,2',3',4'-Penta-O-acetylsucrose (PAS) is a carbohydrate that has been found to be a potent inhibitor of the enzyme glycogen phosphorylase. The reductive elimination of the acetyl groups from PAS produces 2,3,4'-tri-O-acetylsucrose (TAS), which is also an inhibitor of glycogen phosphorylase. TAS inhibits this enzyme by binding to the active site and blocking access to the substrate. TAS also inhibits gluconeogenesis in liver cells by competing with glucose for uptake into the cell. In vitro studies have shown that TAS binds to boron trifluoride and lithium aluminum hydride more effectively than it does to diazomethane or detritylation.</p>

<p>Phenyl 2,3,4-tri-O-benzyl-a-L-thiorhamnopyranose is a modified carbohydrate that is synthesized from the saccharide thiorhamnopyranose. The carbonyl group of the saccharide is substituted with phenyl group and then benzylated. Phenyl 2,3,4-tri-O-benzyl-a-L-thiorhamnopyranose is a white powder that has a CAS number, can be custom synthesized to order, and has high purity. It can be used in glycosylation reactions as well as click modification reactions, which are modifications to the molecule that increase its stability and allow it to react more readily with other molecules.</p>

<p>Rhamnose based 'green' surfactant</p>

<p>1,6,6'-Tri-O-tritylsucrose pentaacetate is a sugar that is synthesized by the process of fluorination and monosaccharide. It has a molecular formula of C12H18O9F. This compound can be used as a synthetic sugar in glycosylation reactions or as an Oligosaccharide for complex carbohydrate synthesis. The 1,6,6'-Tri-O-tritylsucrose pentaacetate can also be modified with methylation or click chemistry for high purity.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Please enquire for more information about 8-D-Glucopyranosyl-7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-O-Benzyl-5,6-di-O-acetyl-1,2-O-isoproylidene-a-D-glucofuranose is a synthetic compound that can be used as a building block for the synthesis of saccharides and oligosaccharides. The molecule is an alpha D glucose derivative with an acetyl group at C3 and an isopropylidene group at C5. It has great potential in glycosylation reactions due to its high purity and low price.</p>

<p>Computational fluid dynamics (CFD) is the study of fluid flow, a subject which has been studied for over two thousand years. The idea of CFD is to use computers to solve the equations that govern fluid flow and to make predictions about the behavior of gases, liquids and complex fluids in various situations. Computational analysis can be used to calculate how air flows around an object such as a car or plane. This allows engineers to create designs with less drag. Computational analysis can also be used in designing buildings, bridges, and other structures that are exposed to large amounts of wind. <br>CFD is a "convective" computational method because it solves problems by using convection-diffusion equations with appropriate boundary conditions. A "transport" computational method solves problems by solving momentum equations and energy conservation equations simultaneously; this method is often more accurate than convective methods but computationally more expensive. A "laminar" computational method solves problems by solving continuity equations. A "nature</p>

<p>Onitisin 2'-O-glucoside is a modification of the natural oligosaccharide onitisin. It is a complex carbohydrate that belongs to the group of sugars. Onitisin 2'-O-glucoside is custom synthesized and its purity level is high. The chemical structure of this compound consists of a monosaccharide methylated with fluorine, glycosylated, and polysaccharided. This compound has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis.</p>

<p>2-Amino-2-deoxy-D-ribose hydrochloride is a synthetic sugar that can be used to produce oligosaccharides and polysaccharides. It has been shown to have high purity and to be custom synthesized as per requirements. This sugar can also be modified with fluorination, methylation, or click modification.</p>

<p>3,4,6-Tri-O-acetyl-1,2-O-ethylidene-b-D-mannopyranoside is a synthetic glycosylation product of maltose and 1,2-O-ethylidene b-D mannopyranoside. This compound is a high purity product with custom synthesis. 3,4,6Tri acetyl 1,2 O ethylene b D mannopyranoside has the CAS number 630102 81 7.</p>

<p>Please enquire for more information about 4-Methylumbelliferyl α-L-idopyranosiduronic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hyaluronate biotin is a high purity and complex carbohydrate. It is synthesized by methylation, saccharide, polysaccharide, and glycosylation of natural hyaluronic acid. Hyaluronate biotin is a modified form of hyaluronic acid that contains an additional biotin molecule per every 500 kDa of molecular weight. This modification can be used in the development of new drugs or as a supplement to improve joint health.</p>

<p>Galacto-N-biose-PAA-biotin is a carbohydrate that is synthesized by the addition of PAA (polyallylamine) to galactose. This compound can be used in fluorescence labeling and detection of carbohydrates, glycosylation, and polysaccharide synthesis. Galacto-N-biose-PAA-biotin has a CAS number (CAS: 146988-01-4).</p>

<p>(4R)-Benzyl-4-deoxy-4-C-nitromethyl-b-D-arabinopyranoside is a custom synthesis of an oligosaccharide. It is a polysaccharide, which are complex carbohydrates that consist of many sugar molecules linked together. The saccharide in this compound has been modified with methylation and glycosylation, which are important modifications for the structure and function of saccharides. This compound also contains a carbohydrate modification called click chemistry, where two molecules are connected by a copper ion. There is high purity in this compound and it has been fluorinated to increase its biological stability.<br>Molecular Formula: C11H14O6N2O3<br>Molecular Weight: 282.25<br>CAS Number: 383173-71-5<br>Purity: &gt;99%</p>

<p>Methyl 3,4-isopropylidene-b-L-arabinopyranoside is a synthetic saccharide that has been modified by the Click chemistry. Click modification is a method of modifying a complex carbohydrate with a reactive group (e.g., an azide) at one end of the molecule and an electrophile at the other end of the molecule. The resulting product can be used in glycosylation reactions to form complex carbohydrates with various properties. Methyl 3,4-isopropylidene-b-L-arabinopyranoside is used as a precursor for the synthesis of oligosaccharides and polysaccharides. It also has been shown to be effective as an inhibitor of bacterial growth in vitro by inhibiting protein synthesis.</p>

<p>6-(4-Azido-2-hydroxybenzamido)-6-deoxy-D-glucopyranose (AGB) is a potential photoaffinity label that can be used to identify and characterize the transporter. The photoaffinity label is synthesized by reacting 2,4-dinitrophenylhydrazine with 6-(4-azido-2-hydroxybenzamido)-6-deoxy-D-glucopyranose in the presence of sodium bicarbonate or potassium carbonate. The photolysis of AGB produces an azide radical cation that reacts with amino acid residues on the protein surface, forming a covalent bond. This labeling process is irreversible.</p>

<p>Prepared by high resolution gel filtration of partial chondroitin ABC lyase digestion of mixed isomer chondroitin sulfate.Average MW ~ 992General formula:∆UA – (GalNAc,6S or 4S - GlcA)n - GalNAc,6S or 4Swhere n is number of disaccharide units n = 1 in a tetrasaccharide (dp4) Uronic acid (∆UA) at the non-reducing ends of the oligosaccharides has a C4-C5 double bond as a result of endolytic scission. The main disaccharide repeat in the original chondroitin sulphate is GlcA – GalNAc sulphated at C-6 or C-4 of the GalNAc residue; the CSD disaccharide unit (GlcA,2S – GalNAc,6S) is a minor component comprising approx. 5% of total disaccharides.</p>

<p>3,4-Di-O-benzyl-L-rhamnal is a high purity Glycosylation Oligosaccharide with a CAS No. 117249-17-9 that is synthesized by Click modification and methylation. It can be used as a raw material in the synthesis of complex carbohydrate. 3,4-Di-O-benzyl-L-rhamnal is water soluble and has an excellent stability in acidic conditions.</p>

<p>Myo-inositol-d6 is a stable isotope of myo-inositol. It is used to monitor the biosynthesis of myo-inositol in yeast cells. Myo-inositol is a carbohydrate that has regulatory functions in yeast cells. Myo-inositol-d6 can be used as an extracellular bioassay for determining the uptake and intracellular distribution of myo-inositol in mammalian cells.</p>

<p>Methyl a-L-acosamine hydrochloride is a custom synthesis that belongs to the class of complex carbohydrates. It has been modified with methylation, glycosylation, and carbocation modification. This product is also fluorinated and has a high purity level. It can be used as an intermediate in the production of saccharides and other products.</p>

<p>The 6-O-(a-D-galactopyranosyl)-D-mannopyranose, also known as epimelibiose, is an oligosaccharide formed by linking an α-D-galactose molecule to a D-mannose molecule. It could be found in various natural products or glycoconjugates, such as glycolipids or glycoproteins. The configuration and linkage of sugars in such molecules often play a crucial role in their biological functions. 6-O-(a-D-galactopyranosyl)-D-mannopyranose can be used in research to modify polysaccharides and glycans. It has a role as a plant metabolite and a mouse metabolite.</p>

<p>Globotriose conjugated to human serum albumin (HSA)</p>

<p>2,3,4,6-Tetra-O-acetyl-N-(b-D-galactopyranosyl)-N'-[(2-methanethiosulfonyl)ethyl]urea is a glycoside that has been custom synthesized for a sugar. This product is fluorinated and has a purity of 99%. It can be used as an intermediate in the Click modification reaction. It is available in bulk quantities and can be customized to meet customer needs.</p>

<p>Acetylsalicylic acid-acyl-b-D-glucuronide is a glycosylation product of acetylsalicylic acid. It is a complex carbohydrate that can be methylated, fluorinated, or modified by click chemistry. Acetylsalicylic acid-acyl-b-D-glucuronide has been shown to be an effective inhibitor of the MMPs metalloproteinases and collagenase in vitro. It also inhibits the growth of Staphylococcus aureus, Streptococcus agalactiae, and Group A Streptococcus. Acetylsalicylic acid-acyl-b-D-glucuronide can be synthesized using monosaccharides, oligosaccharides, or custom synthesis. This product is available in high purity (99%) and CAS No. 24719-72-0.</p>

<p>Undecylenyl b-D-maltoside is a high purity sugar that can be custom synthesized. It is fluorinated at the hydroxyl group, glycosylated, and methylated. This product is also available in various configurations including oligosaccharides, monosaccharides, and complex carbohydrates. <br>Undecylenyl b-D-maltoside is a carbohydrate that can be used as a synthetic building block for the synthesis of other sugars. It can also be used for glycosylation reactions to create new glycoconjugates with improved properties. Undecylenyl b-D-maltoside is an oligosaccharide with a saccharide chain consisting of 10 units of D-glucose and one unit of D-mannose. The individual units are linked together by alpha 1,6 bonds.</p>

<p>Nonanoyl-N-Hydroxyethylglucamide is a novel methylation and click modification reagent that has been shown to be highly effective for the methylation of carbohydrates. It is also a potent fluorinating agent, which can be used for the preparation of complex carbohydrates, such as oligosaccharides and polysaccharides. Nonanoyl-N-Hydroxyethylglucamide is available in high purity and with various modifications.</p>