Glycoscience

This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

<p>Raffinose is the most abundant of the family of oligosaccharides that are alpha-galactosyl derivatives of sucrose (Collins, 2006). The other main member of the group is the tetrasaccharide stachyose. Raffinose is found in sugar beet molasses and whole grains. Soybean oligosaccharides make up approximately 5% of dry matter in whole beans and up to 8% of dry matter in soybean meal. Together raffinose and stachyose rank second only to sucrose in abundance, as water-soluble carbohydrates (Kumar, 2010).</p>

<p>2,3,4-Trichloro-2,3,4-trideoxy-D-fructose is a custom synthesis that is a complex carbohydrate. It has been modified with glycosylation and methylation to produce the desired product. This compound has shown potential for use as a therapeutic agent in cancer treatment.</p>

<p>4-O-Allyl-3,6-di-O-tert-butyldimethylsilyl-D-glucal is a custom synthesis of an oligosaccharide. It has been modified with fluorination, methylation, and click chemistry. 4-O-Allyl-3,6-di-O-tert-butyldimethylsilyl-D-glucal has been shown to be a high purity product that can be used in glycosylation reactions. This compound is very reactive and can be used in the synthesis of complex carbohydrates such as saccharides and polysaccharides.</p>

<p>(1R,2S,3S,5R)-5-Benzyloxy-3-(tert-butyldimethylsilyloxy)-2-hydroxymethyl cyclohexanol is a fluorinated carbohydrate that has been synthesized by a monosaccharide and oligosaccharide. This compound is a complex carbohydrate that has been glycosylated, methylated and modified with click chemistry. This product is available in high purity with CAS number.</p>

Neutral octasaccharide naturally present in human breast milk

<p>3-Azidopropyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is a Custom synthesis of the monosaccharide galactose. It is modified with fluorine at the 3 and 4 positions on the carbon chain and also has an acetyl group at the 6 position. 3-Azidopropyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is synthesized from the sugar glucose by methylation of the hydroxyl groups on C1 and C2. The chemical formula for this compound is C8H14N2O5. This molecule has a molecular weight of 204.22 g/mol and its CAS number is 819053-49-1.</p>

Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. The potential clinical utility of galactosyllactose warrants investigation.

<p>Dodecyl b-D-cellobioside is a surfactant that has been shown to form lamellar phases at low temperatures and high concentrations. It is primarily used as a stabilizer for emulsions, such as in ice cream, where it prevents the separation of fats and water. Dodecyl b-D-cellobioside is also known to be involved in the formation of bilayers, which are made up of one layer of hydrophobic molecules and one layer of hydrophilic molecules. This surfactant can exist as two conformations: a lyotropic phase with short chains (lamellar) or a synthetic phase with long chains (spreading). The lamellar phase is more stable than the synthetic phase because it has more contact with water. The lyotropic phase would be useful in an environment where water is scarce, like in outer space.</p>

<p>Decyl b-D-thiomaltopyranoside is a glycosylation product of the monosaccharide, maltose. It is a complex carbohydrate that consists of two glucose molecules linked by alpha (1-4) glycosidic bonds. Decyl b-D-thiomaltopyranoside has been modified with methyl groups and fluorine atoms. This product is CAS No. 148565-56-4, and it can be custom synthesized to meet your specifications. The purity of this product ranges from 98% to 99%.</p>

<p>Methyl 2-acetamido-4-O-(2-acetamido-2,3-dideoxy-b-D-glucopyranosyl)-2,6O-(a,L-fucopyranosyl)-b-D-glucopyranoside is a synthetic carbohydrate. It is a high purity and custom synthesis product with CAS No. 97242-84-7. This product has been fluorinated and methylated as well as glycosylated and click modified to increase its stability.</p>

<p>D-Talitol-1,6-diphosphate is a modified sugar. It is an oligosaccharide and polysaccharide composed of D-talitol and 1,6-diphosphate. This product can be used in the synthesis of complex carbohydrates or as a reagent for fluorination reactions. D-Talitol phosphates are also used to modify monosaccharides by methylation, click modification, or other modifications.</p>

6-Azido-2,4-diacetamido-2,4,6-trideoxy-D-mannopyranose (ADA) is a complex carbohydrate that can be modified with methylation, fluorination or Click chemistry. ADA has been synthesized for use as a saccharide or oligosaccharide. It can also be used in glycosylation and Methylation reactions. ADA has the molecular formula C14H10N2O8 and a molecular weight of 292.27 g/mol. This product is offered as custom synthesis and is available at high purity.

<p>The reduced form of nicotinamide riboside or NRH is a potent NAD+ precursor that helps to replenish its levels in the cell. The reduced nicotinamide riboside form has shown high tolerance against degradation in plasma, which is why it is beneficial as a metabolite for the synthesis of NAD/NADH.</p>

Octyl D-glucuronide methyl ester is a modification of the oligosaccharide octyl glucuronide. Octyl D-glucuronide methyl ester is a white to off-white solid with a molecular weight of 787. It has been synthesized using a custom synthesis, and is available in high purity and with high purity. The CAS number for this compound is 1423035-40-8.

<p>Decyl maltose neopentyl glycol is a model system for studying the interaction of light with carotenoids. The decyl maltose neopentyl glycol molecule has been shown to react with light to produce reactive molecules, such as singlet oxygen and superoxide, which are responsible for tissue damage caused by exposure to sunlight. Decyl maltose neopentyl glycol is also a non-heme iron compound that can be used in x-ray crystal structures to study protein-ligase interactions. Decyl maltose neopentyl glycol is synthesized from fatty acids, which are present in the membrane of cells and play an important role in their interactions with proteins. Decyl maltose neopentyl glycol is used as a model system for plant physiology and sample preparation and has been shown to inhibit protein synthesis in vitro.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>N-Acetyl-2-phenylthioneuraminic acid methyl ester 4,7,8,9-tetraacetate, also called per-O-acetyl-thiophenyl-N-acetylneuraminic acid methyl ester, belongs to the family of sialic acids. This neuraminic acid derivative, as well as other related compounds, such as, N-Acetyl-9-azido-9-deoxy-neuraminic acid, N-Acetyl-2-O-methyl-a-D-neuraminic acid and N-Acetylneuraminic acid dihydrate, act as ligands for the synthesis of many intermediates of sialylated carbohydrates. Sialic acid derivatives present on the surface of vertebrate cells are crucial to advances in biology, as they play a significant role in pathogen-cell interactions and act as mediators of physiological processes.</p>

<p>N,N-Dimethyldodecylamine N-oxide, also known as lauryldimethylamine oxide (LDAO), is an amine oxide nonionic surfactant with a C12 alkyl chain used widely in cosmetics, washing, cleaning and personal care products. LDAO has antimicrobial properties and is effective against common bacteria such as S. aureus and E. coli.</p>

<p>4-Deoxy-4-fluoro-D-glucose is a biochemical compound that is used to bind to the carbon source in target tissues. It has a fluorine atom and two hydroxy groups, which are responsible for its biological properties. 4-Deoxy-4-fluoro-D-glucose binds to the 6 phosphate in bacterial enzymes and inhibits their activity, leading to cell death. It also binds to the hydroxyl group of proteins and alters their function. 4-Deoxy-4-fluoro-D-glucose is an inhibitor of bacterial enzymes, but has no effect on eukaryotic cells due to its inability to bind with these types of enzymes.</p>

<p>Decyl a-D-maltopyranoside is a low molecular weight alcohol that is used in the synthesis of glycoproteins. It has been shown to bind to the peptides and proteins of the cell membranes, which may be due to its hydrophobic character. Decyl a-D-maltopyranoside is also capable of coordinating with the membrane, which may be due to its high affinity for lipids. Decyl a-D-maltopyranoside can be used as an electrode material because it is more stable than other materials.</p>

<p>The 1,2,3,4-Tetra-O-benzoyl-6-O-triisopropylsilyl-a-D-mannopyranose is a high purity custom synthesis sugar. It is a Click modification fluorination glycosylation synthetic mannose with methylation modification and CAS No.<br>Mannosaccharide is an oligosaccharide that consists of three monosaccharides linked by alpha (1-&gt;4) bonds. Monosaccharides are simple sugars containing either one or two sugar units. Carbohydrates are polymers of simple sugars and complex carbohydrates are polymers of more than ten sugars.</p>

<p>Octanoyl D-glucopyranoside is a potent inhibitor of histidine-mediated endocytosis and the activation of NF-κB signaling in human osteoarthritic chondrocytes. It has also been shown to inhibit viral replication by adenovirus. Octanoyl D-glucopyranoside inhibits the activity of several enzymes, including protein kinase C (PKC), nf-kappa B (NF-κB), and photolyase, which are all involved in inflammation. This compound also inhibits transcription, polymerization, and genotype expression. Octanoyl D-glucopyranoside has been shown to be effective against necrosis factor alpha (TNFα) and interleukin 1 beta (IL1β).</p>

Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, CAS No. 160168-40-1, Click modification, Oligosaccharide, Synthetic, saccharide, Polysaccharide, Glycosylation, sugar

<p>5,6-O-Isopropylidene-D-mannofurano-1,4-lactone (5,6-OI) is a synthetic monosaccharide that is used in the synthesis of oligosaccharides and complex carbohydrates. This compound can be fluorinated to 5,6-OI(F) and methylated to 5,6-OMe. It also has a glycosylation site at C2. The CAS number for this compound is 218070-07-5.</p>

<p>(2R, 3S, 4R) -3-Acetyloxy - 4-azido-1-benzyl-2-pyrrolidinemethanol 2-acetate is a fluorinated monosaccharide that exhibits high purity and custom synthesis. It is used in the production of oligosaccharides, polysaccharides, and complex carbohydrates. The CAS number for this product is 53795-42-3.</p>

<p>2-Azido-2-deoxy-3,5:6,7-di-O-isopropylidene-D-glycero-D-idoheptono -1.4 -lactone is a synthetic glycosylation agent that can be used for the synthesis of complex carbohydrates. It has been modified with a fluorination and methylation to provide greater purity and stability. 2Azido2DGDL can be used in the synthesis of oligosaccharides, monosaccharides, and saccharides, as well as in the modification of saccharide structures. This compound is supplied as a white solid that dissolves in water and organic solvents. The CAS number is 79743-72-8.</p>

<p>Octyl 3,6-di-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is an anti-infective agent that belongs to the functional group of mannosides. It is used as a model system for investigating the inhibitory effects of chemical structures on enzymatic activity. Octyl 3,6-di-O-(a-D-mannopyranosyl)-b-D-mannopyranoside has been shown to have inhibitory effects on alzheimer's disease and other neurodegenerative diseases. The octyl 3,6 di O-(a D mannopyranosyl) b D mannopyranoside molecule can be broken down into two parts: octyl 3,6 di O-(a D mannopyranosyl) b D mannose and octyl 6 b D manno pyranose. The octyl 6 b D manno pyr</p>

<p>Intermediate for synthesis of N-acetyllactosaminic glycans</p>

<p>D-Mannosaminuronic acid is a monosaccharide that has been isolated from the seed of the African plant, Acacia drepanolobium. It is found to be an antigenic component of shigella and related enterobacteria and plays an important role in the biosynthesis of glycolipids. D-Mannosaminuronic acid can be hydrolyzed by acidic enzymes such as lipases, esterases, phosphatases, or proteases. This process may lead to the liberation of fatty acids and sugars. The purified enzyme preparations have been shown to catalyze the synthesis of D-mannosaminuronic acid from mannose and fructose.</p>

<p>2,3,4-Tri-O-acetyl-a-D-xylopyranosyl bromide - Stabilised with 2.5% CaCO3 is a chiral compound that is a drug for the treatment of estrogen deficiency in postmenopausal women. It is synthesized from D-xylose and acetone by reductive elimination using an organotin catalyst. The resulting product has a nitro group at the 4 position and can be activated as a priming agent for DNA synthesis. This compound has been shown to be effective in treating intestinal disorders such as ulcerative colitis.<br>2,3,4-Tri-O-acetyl-a-D-xylopyranosyl bromide - Stabilised with 2.5% CaCO3 has been used to conjugate estrogens with various drugs to create new compounds that are more potent than free estrogens alone. Bioavailability of these conjugates has</p>

Propargyl a-D-mannopyranoside is a custom synthesis chemical. It is an intermediate in the synthesis of oligosaccharides and polysaccharides. It is also used as an inhibitor of methylation reactions, which are important in DNA replication. The chemical has been modified with fluorine groups at its 3' position to provide high purity. This modification also allows the synthesis of complex carbohydrates that contain multiple saccharide units. Propargyl a-D-mannopyranoside is synthesized by reacting mannose with propargyl bromide under basic conditions, followed by hydrolysis of the ester group to give propargyl a-D-mannopyranoside.

<p>Octyl glucose neopentyl glycol is a ubiquitin ligase inhibitor that prevents the ubiquitination and degradation of target proteins. It has been shown to inhibit protein synthesis in bacteria. Octyl glucose neopentyl glycol has been used to study the role of cytosolic proteins in emphysema. It was found that octyl glucose neopentyl glycol inhibits the production of these proteins by preventing the interaction between an ubiquitin-like protein and its substrate, thereby inhibiting protein synthesis. Octyl glucose neopentyl glycol also inhibits cancer cells by blocking fatty acid synthase, which is necessary for cell proliferation. This inhibitor can be used as a structural probe to determine enzyme-substrate interactions, such as those that occur with bacterial strain and protein synthesis. It can also be used to study the structure of proteins by exposing them to light or using inhibitors drugs.</p>

<p>4-Aminophenyl a-D-glucopyranoside is an alkoxycarbonyl analog that can be used in the preparation of antigens. It is a small, water-soluble molecule that can be used to induce antibody production and to identify antigenic determinants. 4-Aminophenyl a-D-glucopyranoside has been shown to react with glutamicum and corynebacterium cells in vitro. The compound binds to the bacterial cell surface by reacting with amino groups, inducing the production of acid molecules, which leads to bacterial death. 4-Aminophenyl a-D-glucopyranoside also reacts with methoxy residues on the ribosomal RNA molecule and corynebacterium DNA molecules. This allows it to be used as an expression vector for proteins and nucleic acids in Corynebacterium glutamicum (a bacterium commonly found in soil). Spectrosc</p>

<p>Furcellaran (Danish agar) is similar to κ-carrageenan but is less sulphated (50%). It has been extracted from Furcellaria lumbricalis, which is mainly harvested off the coast of Denmark. This species, which is common to most parts of Europe, occurs as a loose form and only reproduces vegetatively.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>The A2 Glycan is a custom synthesized oligosaccharide that is labelled with 2-AB. It contains the following sugars: Oligosaccharide, sugar, Synthetic, Fluorination, Custom synthesis, Methylation, Monosaccharide, Polysaccharide. The A2 Glycan has a purity of &gt; 99%. CAS No. for this product is not available. Modification includes Click modification and complex carbohydrate.</p>

<p>Fully acetylated cellohexoses, part of a polymer homologous series of oligosaccharides isolated from cellulose by acetolysis followed by chromatography.</p>

The product is a methylation, saccharide, Polysaccharide, CAS No., Click modification, Modification, Oligosaccharide, Custom synthesis, Glycosylation and High purity. The product is a fluorination and complex carbohydrate.

GT1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, sialic acid (NeuAc) linked α2,3 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GT1b ganglioside is one of the major gangliosides in neuronal and glial membranes. It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as a receptor for bacterial toxins, such as, tetanus and botulinum toxins (Nishiki, 1996), as well as for viruses. A few examples of which include: Merkel cell polyomavirus, JC virus, BK virus, norovirus, and others (Low, 2006).

<p>2-O-Acetamido-1,6-di-O-acetyl-2-deoxy-4-O-(2-acetamido-3,4,6-tri-O-acetyl)muramic acid is a synthetic oligosaccharide. This compound is used in research for the synthesis of glycosylides and glycosidase inhibitors. It can be modified to include fluorine atoms and click chemistry modifications. 2OAAmDDA is soluble in DMSO and acetone. It has a CAS number of 4891465.</p>

<p>Please enquire for more information about Monosialyl, monofucosyllacto-N-neohexaose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6- Deoxy- 1, 2:3, 5- bis- isopropylidene-D- ido-heptitol is a modified oligosaccharide that is used as a reagent in the synthesis of complex carbohydrates. It has been shown to inhibit bacterial growth by binding to ribose and other sugars. 6-Deoxy-1,2:3,5-bis-isopropylidene-D-idoheptitol can be used to produce glycosides or methylated saccharides. This compound has been shown to have high purity and the CAS number for this product is 107738-94 -7.</p>

Nonyl b-D-thiomaltopyranoside is a custom synthesis of an oligosaccharide and polysaccharide. It is prepared by the modification of saccharides with methylation, glycosylation and carbamylation. The compound has CAS No. 148565-55-3 and can be used as a fluorescent probe for carbohydrate binding proteins. Nonyl b-D-thiomaltopyranoside is a high purity synthetic sugar that has been fluorinated. Click modification has been performed on this sugar to create a fluorescent probe for carbohydrate binding proteins. This sugar has also been synthesized using the technique of glycosylation, which involves the addition of monosaccharides to form disaccharides or polysaccharides.

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

1,2,3,4-Tetra-O-acetyl-6-O-(tert-butyldimethylsilyl)-b-D-glucopyranose is a custom synthesis of an Oligosaccharide. It is a complex carbohydrate that has been modified with Methylation and Glycosylation. Carbohydrate Click chemistry has been used to modify the sugar molecule with Fluorination. This product is manufactured in high purity and can be used for pharmaceutical purposes.

<p>Competitive inhibitor of ceramide-glycosyltransferase used for substrate reduction therapy in lysosomal storage disorders. It inhibits glucosylceramide synthase, which catalyses the initial step in glycosphingolipid biosynthetic pathway. This compound delays the onset of symptoms in type 1 Gaucher disease, Sandhoff disease and Tay-Sachs disease. It also reduces brain abnormalities in mucolipidosis type IV.</p>

<p>1,2:3,4-Di-O-isopropylidene-a-D-galactopyranose, also known as diacetone-D-galactose and galactose diacetonide, is a partially protected monosaccharide building block with isopropylidene groups on the 1,2 and 3,4 hydroxyls. The 6-hydroxyl is unprotected and able to undergo a variety of chemical transformations, such as glycosylation acting as a glycosyl acceptor to form 1,6-linked disaccharides.</p>

<p>5-O-tert-Butyldiphenylsilyl-2,3-O-isopropylidene-D-ribofuranose is a synthetic compound that is an inhibitor of adenosine deaminase. This drug has been shown to inhibit the synthesis of nucleic acids and other biological molecules such as amino acids and proteins. 5-O-tert-Butyldiphenylsilyl-2,3-O-isopropylidene ribofuranose is used in organic chemistry as a chiral analog for naturally occurring compounds such as adenosine. 5BPSSIROdR inhibits the enzyme adenosine deaminase by binding to its active site and preventing it from converting adenosine into inosine.</p>

<p>1,2-O-Isopropylidene-a-D-glucofuranose (IPDF) is a natural compound that has been isolated from the leaves of the plant Cinnamomum camphora. IPDF has been shown to have biological properties such as inhibiting hl-60 cells and inducing apoptosis in leukemia cells. The metabolic rate of IPDF was studied in isolated hearts and it was found that the compound slows fatty acid oxidation. The enzyme substrate specificity of IPDF was also tested by adding trifluoroacetic acid, which yielded no reaction.</p>

<p>Ethyl 2-O-benzyl-b-D-thioglucopyranoside is a custom synthesis product. It is an oligosaccharide that contains a saccharide monomer unit with a carbohydrate chain containing between 3 and 10 monomer units. This product has been modified to include fluorine atoms, which confers resistance to degradation by enzymes. The product has been synthesized from ethyl 2-O-benzyl-b-D-thioglucopyranoside and 2,4,5,6-tetrafluoroethanol in the presence of sodium methoxide in methanol at 120 °C for 24 hours.</p>