Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 906 products of "Antifungals"
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Propiconazole
CAS:Propiconazole is a triazole fungicide with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for controlling fungal diseases in crops and turf.
Formula:C15H17Cl2N3O2Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:342.22 g/molMiconazole
CAS:Anti-fungal; sterol 14α-demethylase inhibitorFormula:C18H14Cl4N2OPurity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:416.13 g/molBeauvericin
CAS:Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.
Formula:C45H57N3O9Purity:Min. 95%Molecular weight:783.95 g/molLevofloxacin
CAS:Levofloxacin is a fluoroquinolone antibiotic with a mode of action that inhibits bacterial DNA gyrase and topoisomerase IV. It is used for treating bacterial infections like pneumonia and urinary tract infections.Formula:C18H20FN3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:361.37 g/molSordarin sodium salt
CAS:Sordarin sodium salt is an antifungal agent, characterized as a semisynthetic derivative produced from the fermentation products of filamentous fungi, specifically belonging to the phylum Ascomycota. This compound exerts its effects by selectively inhibiting fungal protein synthesis. It achieves this by obstructing the function of elongation factor 2 (EF-2), an essential component of fungal ribosomal activity, thereby disrupting the translational elongation step of protein synthesis.
Formula:C27H39NaO8Purity:Min. 95%Molecular weight:514.58 g/mol2-Methyl-4-isothiazolin-3-one
CAS:Controlled Product2-Methyl-4-isothiazolin-3-one or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products. It is also used in industrial applications as a preservative and antifouling agent.Formula:C4H5NOSPurity:Min. 96%Color and Shape:Yellow PowderMolecular weight:115.15 g/molZelkovamycin
CAS:Zelkovamycin is a novel antibacterial compound isolated from endophytic microorganisms, specifically Streptomyces sp. Endophytes are bacteria or fungi that reside within plant tissues, forming symbiotic relationships and often producing bioactive metabolites. The mode of action of Zelkovamycin involves the inhibition of bacterial cell wall synthesis, interfering with the biosynthesis pathways essential for maintaining the structural integrity and function of bacterial cell walls, particularly in Gram-positive strains.Formula:C36H45N9O9SPurity:Min. 95%Color and Shape:PowderMolecular weight:779.86 g/molChaetochromin
CAS:Chaetochromin (4548-G05, NSC 345647) is an oral, selective insulin receptor agonist with potent, lasting antidiabetic effects in mice.Formula:C30H26O10Color and Shape:SolidMolecular weight:546.52Pyrisoxazole
CAS:Pyrisoxazole is a novel fungicide inhibitor of Sterol 14α-demethylase.Formula:C16H17ClN2OColor and Shape:SolidMolecular weight:288.77Antifungal agent 30
CAS:Potent antifungal, works against Candida albicans (MIC: 0.03 μg/mL) & Aspergillus fumigatus (MIC: 0.5 μg/mL) via CYP51 interactions.Formula:C18H14Cl2F2N2SeColor and Shape:SolidMolecular weight:446.18Antibacterial agent 67
CAS:Antibacterial agent 67 blocks succinate dehydrogenase more effectively than haloperidol, with IC50 of 0.03 μM vs 4.40 μM.Formula:C24H15F6N5OColor and Shape:SolidMolecular weight:503.4Diamthazole hydrochloride
CAS:Diamthazole (Dimazole) hydrochloride, an antifungal agent, is utilized in infection research.Formula:C15H24ClN3OSColor and Shape:SolidMolecular weight:329.89CYP51/HDAC-IN-1
CAS:Orally active CYP51/HDAC-IN-1 dual inhibitor targets virulence factors and resistance genes; effective against Candidiasis and Cryptococcal meningitis.Formula:C30H40F2N6O4Color and Shape:SolidMolecular weight:586.67β-Nor-lapachone
CAS:β-Nor-lapachone is an antibiofilm agent of Candida glabrata.Formula:C14H12O3Color and Shape:SolidMolecular weight:228.24Antifungal agent 46
CAS:Compound 2f (Antifungal Agent 46) is a potent antifungal that inhibits Ras signaling by targeting protein farnesyltransferase [1].Formula:C26H28BrF3N4O2Purity:98%Color and Shape:SolidMolecular weight:565.43Isobellidifolin
CAS:Isobellidifolin, a xanthone compound, serves as a free radical scavenger and antioxidant. It exhibits a potent antifungal effect.Formula:C14H10O6Color and Shape:SolidMolecular weight:274.23Apogossypolone (ApoG2)
CAS:Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K iFormula:C28H26O8Color and Shape:SolidMolecular weight:490.5Antifungal agent 68
CAS:Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterolFormula:C23H27ClN2O3Color and Shape:SolidMolecular weight:414.93Tolindate
CAS:Tolindate, a potent PXR agonist, demonstrates antifungal activity and possesses an EC50 value of 8.3 µM.Formula:C18H19NOSColor and Shape:SolidMolecular weight:297.41Antifungal agent 32
CAS:Antifungal 32 (1a) strongly inhibits Candida albicans growth, filamentation, biofilm, and adhesion.Formula:C25H28N2OColor and Shape:SolidMolecular weight:372.55-Aminouridine
CAS:5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.Formula:C9H13N3O6Purity:99.53%Color and Shape:SolidMolecular weight:259.22Metyltetraprole
CAS:Metyltetraprole: potent fungicide, effective against Zymoseptoria, low EC50 (0.002 ppm), inhibits respiratory chain.Formula:C19H17ClN6O2Color and Shape:SolidMolecular weight:396.83P163-0892
CAS:P163-0892: potent, specific antifungal for Cryptococcus; moderate blood-brain barrier penetration.Formula:C19H20N2O3SColor and Shape:SolidMolecular weight:356.44Antifungal agent 22
CAS:Orally active antifungal D16 (IC50: 0.5 μg/mL) passes blood-brain barrier, stable, low toxicity, targets C. neoformansH99 cells.Formula:C21H26Cl3NOSColor and Shape:SolidMolecular weight:446.86Posaconazole hydrate
CAS:Posaconazole: broad-spectrum antifungal, second-gen triazole, strong C14α demethylase inhibitor (IC50: 0.25 nM).Formula:C37H44F2N8O5Purity:98%Color and Shape:SolidMolecular weight:718.79Silthiofam
CAS:Silthiofam effectively combats Ggt, a wheat take-all fungus, now widely used for control in China.Formula:C13H21NOSSiPurity:98%Color and Shape:SolidMolecular weight:267.46Hexamide
CAS:Hexamide is a protein inhibitor.Formula:C13H17NOColor and Shape:SolidMolecular weight:203.28Globosuxanthone A
CAS:Globosuxanthone A: a dihydroxanthenone with anticancer and antifungal properties (MIC: F. graminearum 4, F. solani 8, B. cinerea 16 μg/mL).Formula:C15H12O7Color and Shape:SolidMolecular weight:304.25Zarilamide
CAS:Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.Formula:C11H11ClN2O2Color and Shape:SolidMolecular weight:238.67Antifungal agent 59
CAS:Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, whileFormula:C18H15BrF2N2SeColor and Shape:SolidMolecular weight:456.19Chlordantoin
CAS:Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment.Formula:C11H17Cl3N2O2SPurity:98%Color and Shape:SolidMolecular weight:347.69Chitin synthase inhibitor 3
CAS:Compound 2d is a potent chitin synthase inhibitor (IC50: 0.16 mM, MIC: 1 μg/mL vs. Candida albicans) with antifungal properties.Formula:C20H19N3O4Color and Shape:SolidMolecular weight:365.38Etisazole
CAS:Etisazole is an animal antifungal agent with skin sensitizing properties to humans.Formula:C9H10N2SColor and Shape:SolidMolecular weight:178.25Exalamide
CAS:Exalamide (2-(Hexyloxy)benzamide) is an aromatic amide with antifungal activity used in the study of dermatophytes.Formula:C13H19NO2Purity:99.61%Color and Shape:White PowderMolecular weight:221.3Antifungal agent 31
CAS:Orally active triazole, antifungal 31 with pyrrolizinone structure, combats Candida, reduces mortality and renal infection in mice.Formula:C25H22F2N6O3Color and Shape:SolidMolecular weight:492.48(Z)-Fluoxastrobin
CAS:(Z)-Fluoxastrobin is a fungicide that exhibits effective control of important seed and soil-borne pathogens.Formula:C21H16ClFN4O5Color and Shape:SolidMolecular weight:458.83Flutolanil
CAS:Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.Formula:C17H16F3NO2Color and Shape:SolidMolecular weight:323.31Stemphyperylenol
CAS:Stemphyperylenol: antifungal, targets Alternaria solani, MIC at 1.57 μM.Formula:C20H16O6Color and Shape:SolidMolecular weight:352.34Haloprogin
CAS:Haloprogin is an antifungal agent with inhibitory activity against dermatophytes, Candida, and some Gram-positive bacteria.Formula:C9H4Cl3IOPurity:98.18%Color and Shape:SolidMolecular weight:361.39Antifungal agent 69
CAS:Antifungal agent 69 (compound 13), a eugenol-imidazole derivative, demonstrates targeted activity against Candida albicans with a minimum inhibitoryFormula:C23H23ClN2O4Color and Shape:SolidMolecular weight:426.89Buclosamide
CAS:Buclosamide is a topical antimycotic agent that can be used in dermatomycoses [1].Formula:C11H14ClNO2Color and Shape:SolidMolecular weight:227.69Chlorothalonil
CAS:Chlorothalonil (DAC 2787): Broad-spectrum, efficient, low-toxicity fungicide for fruits, vegetables, rice, wheat, cotton.Formula:C8Cl4N2Purity:98.01% - 98.71%Color and Shape:Colorless Crystals SolidMolecular weight:265.91Antifungal agent 73
CAS:Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane.Formula:C21H16Cl2N2O3Color and Shape:SolidMolecular weight:415.27Tebuconazole-d9
CAS:Tebuconazole-d9 is a GC/LC-MS standard for quantifying the triazole fungicide tebuconazole, affecting seed/foliar fungi and androgen receptors.Formula:C16H13ClD9N3OColor and Shape:SolidMolecular weight:316.87Succinate dehydrogenase-IN-1
CAS:Succinate dehydrogenase-IN-1 (Compound 34) acts as an inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 0.94 μM and a KD of 22.4 μM. This compound also demonstrates antifungal activity, with EC50 values against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea measured at 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively.Formula:C20H13F6N3OColor and Shape:SolidMolecular weight:425.33DHMB
CAS:DHMB (2,3-Dihydroxy-4-Methoxybenzaldehyde) exerts protective effects on intestinal epithelial cells. DHMB exhibits anti-inflammatory and antifungal capacity.Formula:C8H8O4Purity:99.57%Color and Shape:SolidMolecular weight:168.15S-F24
CAS:S-F24 is a broad-spectrum antifungal agent that demonstrates potent inhibition of CYP3A4, with an IC50 of 0.4 μM.Formula:C25H27BrF2N6OColor and Shape:SolidMolecular weight:545.42Fosravuconazole
CAS:Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.Formula:C23H20F2N5O5PSPurity:98%Color and Shape:SolidMolecular weight:547.47Antifungal agent 35
CAS:Antifungal agent 35 is an effective antifungal agent that potentiates the antifungal activity of fluconazole against C. albicans.Formula:C26H27BrN4O4Color and Shape:SolidMolecular weight:539.42Aliconazole
CAS:Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.Formula:C18H13Cl3N2Purity:99.21% - 99.79%Color and Shape:SolidMolecular weight:363.67
