Antifungals
Antifungals are compounds specifically designed to stop, prevent, and eliminate the growth of fungi. In this category, you will find a wide variety of antifungal agents essential for research and therapeutic applications. These compounds are crucial in treating fungal infections and preventing their recurrence, making them vital tools in both medical and agricultural settings. Researchers and healthcare professionals can explore numerous antifungals to understand their mechanisms, optimize their efficacy, and develop new treatments to combat resistant fungal strains. The extensive selection of antifungals supports ongoing advancements in fungal research and the development of effective antifungal therapies.
Found 899 products of "Antifungals"
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(R)-3-hydroxy Myristic Acid
CAS:Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria.Formula:C14H28O3Purity:≥98%Color and Shape:White PowderMolecular weight:244.37Laccase-IN-1
Laccase-IN-1 (compound 4b) is an orally active laccase inhibitor, demonstrating an IC50 of 11.3 μM.Formula:C16H19FN2O3Color and Shape:SolidMolecular weight:306.33Ophiobolin B
CAS:Ophiobolin B is a sesterterpene Helminthosporium oryzae metabolite, inhibits proton extrusion from maize coleoptiles.Formula:C25H38O4Purity:98%Color and Shape:SolidMolecular weight:402.57Kievitone
CAS:Kievitone, an isoflavanone from Phaseolus vulgaris, has antifungal and antitumor properties.Formula:C20H20O6Color and Shape:SolidMolecular weight:356.37Paclobutrazol
CAS:Paclobutrazol ((R,R)-paclobutrazol) is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins.1,2It also has
Formula:C15H20ClN3OPurity:99.23%Color and Shape:Off-White To Beige SolidMolecular weight:293.79Amphotericin B methyl ester
CAS:Amphotericin B methyl ester: a cholesterol-binding antifungal derivative of Amphotericin B; inhibits HIV-1.Formula:C48H75NO17Purity:98%Color and Shape:SolidMolecular weight:938.118Ratjadon
CAS:Ratjadon is an antifungal compound isolated from Sorangium cellulosum.Formula:C28H40O5Purity:98%Color and Shape:SolidMolecular weight:456.61Antifungal agent 108
Antifungalagent 108 (compound 14d) is an original imidazo[1,2-b]pyridazine derivative that exhibits potent antifungal activity against Madurella mycetomatis (MM55 strain) with an IC50 of 0.9 μM. The compound shows an IC50 of 14.3 μM for cell viability in NIH-3T3 mouse fibroblasts.Color and Shape:Odour SolidOxadixyl
CAS:Oxadixyl is used as a fungicide.Formula:C14H18N2O4Purity:98%Color and Shape:SolidMolecular weight:278.30α-Guaiene
CAS:α-Guaiene, a sesquiterpene identified in P. cablin, showcases its presence within this species.Formula:C15H24Color and Shape:SolidMolecular weight:204.35CYP51-IN-24
CYP51-IN-24 (Compound 22) is an inhibitor of Sterol 14α-Demethylase (CYP51). It exhibits potent inhibitory activity against both wild-type and resistant fungi. By binding to the fungal CYP51 enzyme, CYP51-IN-24 prevents the biosynthesis of ergosterol. This compound is applicable in the research and development of treatments for drug-resistant fungal infections.Color and Shape:Odour SolidIturin A
CAS:Iturin A: antifungal compound targeting cell membranes, forms ion pores in yeast/fungi.Color and Shape:SolidAmphotericin B
CAS:Formula:C47H73NO17Purity:≥ 750μg/mg (C47H73NO17, dried basis)Color and Shape:Yellow to dark yellow or orange powderMolecular weight:924.10Latrunculin B
CAS:Latrunculin B: alkaloid, inhibits actin polymerization, antifungal, antiprotozoal, modulates heart rhythm, studied in glaucoma.Formula:C20H29NO5SPurity:98%Color and Shape:SolidMolecular weight:395.51Antibacterial agent 218
Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.Formula:C30H24N4OSMolecular weight:488.16708CYP51-IN-26
CYP51-IN-26 is a CYP51 inhibitor with an IC50 value of approximately 0.40 μM. It effectively eradicates Candida auris biofilms and significantly enhances cellular uptake in accumulation studies. Moreover, CYP51-IN-26 provides protection against Candida auris infection in both G. mellonella and D. melanogaster models. It is applicable for research on fungal infections.Color and Shape:Odour SolidAntifungal agent 62
Compound 3a (Antifungal agent 62) exhibits potent fungicidal properties, particularly against Fusarium oxysporum f.sp.Color and Shape:Odour SolidAntifungal agent 84
CAS:Antifungal Antibacterial agent 84 targets CNB1 to thwart C. albicans biofilm.Formula:C25H19BrClFN6OColor and Shape:SolidMolecular weight:553.81Succinate dehydrogenase-IN-9
Succinate dehydrogenase-IN-9 (Compound Iik) is an inhibitor of succinate dehydrogenase with an IC50 of 3.6 μM. It demonstrates strong inhibitory activity against various fungi, such as S. sclerotiorum, with an EC50 of 1.14 μg/mL. Additionally, Succinate dehydrogenase-IN-9 enhances nitrate reductase activity, promoting plant growth.Formula:C24H29F2N3O5Color and Shape:SolidMolecular weight:477.20753L-4-Oxalysine hydrochloride
CAS:L-4-Oxalysine hydrochloride has shown antitumor activities, is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China.Formula:C5H13ClN2O3Purity:98%Color and Shape:SolidMolecular weight:184.62Tetrahydroechinocandin B
CAS:Tetrahydroechinocandin B is a cyclic hexapeptide containing a fatty acyl side chain. It also inhibits 1,3-beta-D-glucan synthesis.Formula:C52H85N7O16Purity:98%Color and Shape:SolidMolecular weight:1064.273-hydroxy Myristic Acid methyl ester
CAS:3-hydroxy Myristic acid methyl ester found in Eucalyptus, combats M. tuberculosis, non-toxic to Vero cells, and in wild strawberry aroma, not in cultivated.Formula:C15H30O3Color and Shape:SolidMolecular weight:258.402MK-5204
CAS:MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.Formula:C40H65N5O5Color and Shape:SolidMolecular weight:695.99Picarbutrazox
CAS:Picarbutrazox: potent pesticide/fungicide for corn/soybean against Pythium/Phytophthora.Formula:C20H23N7O3Color and Shape:SolidMolecular weight:409.44ent-Heronamide C
Ent-Heronamide C possesses antifungal properties and is utilized as a probe for analyzing the mode of action of heronamide C [1].Formula:C29H41NO3Color and Shape:SolidMolecular weight:451.64FR179642
CAS:FR179642 is a key intermediate for making Micafungin, a drug from the echinocandin class.Formula:C35H52N8O20SColor and Shape:SolidMolecular weight:936.9TPS1-IN-1
TPS1-IN-1 (Compound O1) is a potent and broad-spectrum inhibitor of TPS1. It exhibits IC50 values of 14.73 μM for MoTPS1 (Magnaporthe oryzae TPS1) and 59.99 μM for BcTPS1 (Botrytis cinerea TPS1). TPS1-IN-1 exerts its broad-spectrum fungicidal effects by disrupting spore germination, appressorium formation, and turgor pressure accumulation in fungi. With good safety profiles, TPS1-IN-1 has potential as a candidate for novel fungicide development.Formula:C19H26F3N5O4SColor and Shape:SolidMolecular weight:477.505-epi-Jinkoheremol
CAS:5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.Formula:C15H26OColor and Shape:SolidMolecular weight:222.372Antifungal agent 47
Compound 3b is a potent broad-spectrum fungicide with strong respiratory and ATP synthesis inhibition.Formula:C39H38BrClNO2PColor and Shape:SolidMolecular weight:699.06(−)-Voacangarine
CAS:(–)-Voacangarine, an indole alkaloid isolated from V. africana, exhibits cytotoxicity towards various cell lines including HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 values of 20 µg/ml. Additionally, it demonstrates cytostatic effects on wild-type S. cerevisiae and is cytotoxic to Δrad3-e5 and Δrad6-1 mutant strains of S. cerevisiae, which have defects in DNA strand break repair and the mutagenic repair pathway, respectively.Formula:C22H28N2O4Color and Shape:SolidMolecular weight:384.471,3,6-Trihydroxy-5-methoxyxanthone
1,3,6-Trihydroxy-5-methoxyxanthone is a useful organic compound for research related to life sciences and the catalog number is T124882.Formula:C14H10O6Color and Shape:SolidMolecular weight:274.228Diclobutrazol
CAS:Diclobutrazol: potent systemic fungicide against rusts, mildews, and crop diseases.Formula:C15H19Cl2N3OColor and Shape:SolidMolecular weight:328.24Methyl 3-(1H-indol-3-yl)propanoate
CAS:Methyl 3-(1H-indol-3-yl)propanoate has antifungal activity and is both an analogue of brassinin and a weaker antidote.Formula:C12H13NO2Purity:99.88%Color and Shape:SolidMolecular weight:203.24Concanamycin C
CAS:Concanamycin C, a natural macrolide antibiotic, was initially isolated from Streptomyces and identified as an inhibitor of T-cell proliferation in response to concanavalin A (1,2). It exhibits cytotoxicity to fungi, including yeasts, by inhibiting vacuolar-type ATPases (3,4).Formula:C45H74O13Color and Shape:SolidMolecular weight:823.1Picoxystrobin
CAS:Picoxystrobin, a strobilurin fungicide, halts mitochondrial respiration in plants by blocking electron transfer.Formula:C18H16F3NO4Color and Shape:SolidMolecular weight:367.32Janthitrem F
CAS:Janthitrem F, a naphthopyran also known as 10-O-acetyljanthitrem E, is a tremorgenic mycotoxin produced by Penicillium janthinellum.Formula:C39H51NO7Color and Shape:SolidMolecular weight:645.82Dermaseptin-S1
CAS:Dermaseptin-S1, an antimicrobial peptide sourced from frog skin, exhibits efficacy against filamentous fungi [1].Formula:C152H257N43O44S2Color and Shape:SolidMolecular weight:3455.06LW3
CAS:LW3 is an effective broad-spectrum antifungal compound.Formula:C17H12F3N3OPurity:99.86%Color and Shape:SoildMolecular weight:331.29Liranaftate
CAS:Formula:C18H20N2O2SPurity:≥ 98.0%Color and Shape:White to almost white powder or crystalsMolecular weight:328.43Endo-1,3-β-glucanase
CAS:Endo-1,3-β-glucanase (Lyticase) is a glucanase from fungi and Chlamydomonas reinhardtii that displays lytic activity on fungal cells.Color and Shape:SolidSclerotiorin
CAS:Sclerotiorin, from Penicillium, inhibits soybean lipoxygenase-1 (IC50: 4.2 μM) and other proteins, antagonizes endothelin receptors.Formula:C21H23ClO5Color and Shape:SolidMolecular weight:390.86Deacetylsclerotiorin, (-)-
CAS:deacetylsclerotiorin is a new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550.Formula:C19H21ClO4Color and Shape:SolidMolecular weight:348.82Frequentin
CAS:Frequentin, an antibiotic from P. frequentans, combats bacteria and fungi; MICs: 200 µg/ml for B. subtilis, 300 for S. aureus.Formula:C14H20O4Color and Shape:SolidMolecular weight:252.31Metalaxyl-M
CAS:Metalaxyl-M, an (R)-enantiomer fungicide, inhibits fungi protein/RNA synthesis, used in Oomycota research.Formula:C15H21NO4Color and Shape:SolidMolecular weight:279.33Dermaseptin-S5
CAS:Dermaseptin-S5 is an antimicrobial peptide sourced from frog skin that exhibits activity against filamentous fungi [1].Formula:C128H223N37O35Color and Shape:SolidMolecular weight:2840.37SDH-IN-7
SDH-IN-7 (compound G28) is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 26 nM against porcine SDH and possesses fungicidalFormula:C18H15Cl3F3N3OColor and Shape:SolidMolecular weight:452.69Asperfuran
CAS:Asperfuran is a useful organic compound for research related to life sciences. The catalog number is T125958 and the CAS number is 138331-36-9.Formula:C13H14O3Color and Shape:SolidMolecular weight:218.252Pervicoside B
CAS:Pervicoside B is a triterpene glycoside.Formula:C54H86NaO25SPurity:98%Color and Shape:SolidMolecular weight:1190.31Fenticonazole nitrate
CAS:Formula:C24H20Cl2N2OS·HNO3Purity:(Titration) 98.0 - 102.0 % (anhydrous basis)Color and Shape:White or almost white powderMolecular weight:518.41
