Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 704 products of "Antiparasitics"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Antileishmanial agent-16
CAS:<p>Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 µM) and</p>Formula:C27H37N5O4Purity:98%Color and Shape:SolidMolecular weight:495.61Antileishmanial agent-17
CAS:<p>Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.</p>Formula:C27H37N5O5Purity:98%Color and Shape:SolidMolecular weight:511.61SID 26681509
CAS:<p>SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).</p>Formula:C27H33N5O5SPurity:98.16%Color and Shape:SolidMolecular weight:539.65FIKK9.1-IN-1
CAS:<p>FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1,</p>Formula:C22H22N2SePurity:98%Color and Shape:SolidMolecular weight:393.38ELQ-596
CAS:<p>ELQ-596, a quinolone derivative, exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice [1].</p>Formula:C24H17ClF3NO3Color and Shape:SolidMolecular weight:459.84Fervenulin
CAS:<p>Fervenulin, from Streptomyces sp. CMU-MH021, halts egg hatch (MIC: 30 μg/mL) and kills J2 larvae (MIC: 120 μg/mL) of M. incognita.</p>Formula:C7H7N5O2Purity:99.75%Color and Shape:SolidMolecular weight:193.16Z-Pro-Pro-CHO
CAS:<p>Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01</p>Formula:C18H22N2O4Purity:98%Color and Shape:SolidMolecular weight:330.38BTG 502
CAS:<p>BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).</p>Formula:C21H24BrNOPurity:99.30%Color and Shape:SolidMolecular weight:386.33EDI048
CAS:<p>EDI048, also known as compound 1.16, is an orally active inhibitor of Cryptosporidium PI4K, utilized in the study of cryptosporidiosis [1].</p>Formula:C25H21ClN4O4Purity:98%Color and Shape:SolidMolecular weight:476.91OfChi-h-IN-2
CAS:<p>OfChi-h-IN-2 (compound TQ19) is a potent inhibitor of OfChi-h, exhibiting a K i of 0.33 μM, and significantly impairs the growth and development of Ostrinia</p>Formula:C25H28ClN5O3Purity:98%Color and Shape:SolidMolecular weight:481.98Eugenitin
CAS:<p>Eugenitin, a polyketide from Mycoleptodiscus indicus, exhibits inhibitory activity against Leishmania major with an LD50 of 39.9 μM and demonstrates low</p>Formula:C12H12O4Purity:98%Color and Shape:SolidMolecular weight:220.22Antileishmanial agent-23
CAS:<p>Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM.</p>Formula:C20H17N3O4S2Purity:98%Color and Shape:SolidMolecular weight:427.5Phylloflavan
CAS:<p>Phylloflavan, an antileishmanial compound, exhibits an intracellular half maximal effective concentration (EC50) of 3.2 nM in RAW 264.7 cells and inhibits the</p>Formula:C26H26O10Purity:98%Color and Shape:SolidMolecular weight:498.48MMV688533
CAS:<p>MMV688533 has antimalarial activity.</p>Formula:C24H15F6N5O2Purity:99.12%Color and Shape:SoildMolecular weight:519.4Dehydroemetine
CAS:<p>Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.</p>Formula:C29H38N2O4Purity:98.68% - 99.68%Color and Shape:SolidMolecular weight:478.62ZY-19489
CAS:<p>ZY-19489: Antimalarial, potential single-dose cure, FDA orphan drug status.</p>Formula:C24H32FN9Purity:>99.99%Color and Shape:SoildMolecular weight:465.57GSK3186899
CAS:<p>GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.</p>Formula:C19H28F3N7O3SPurity:98.35% - 99.61%Color and Shape:SolidMolecular weight:491.53CWHM-1552
CAS:<p>CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.</p>Formula:C22H27F2N3OPurity:99.56%Color and Shape:SolidMolecular weight:387.47Ac-Atovaquone
CAS:<p>Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.</p>Formula:C24H21ClO4Color and Shape:SolidMolecular weight:408.87WR-27653
CAS:<p>WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.</p>Formula:C20H36BrN3O2Color and Shape:SolidMolecular weight:430.423
