Antiparasitics
Found 695 products of "Antiparasitics"
PIQ-2
CAS:PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.Formula:C23H21F3N4O3Color and Shape:SolidMolecular weight:458.43PFK-IN-1
CAS:PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.Formula:C18H15Cl2N3O4SColor and Shape:SolidMolecular weight:440.3Ferrocene
CAS:Ferrocene, a crucial structural core in bioorganometallic chemistry, is renowned for its intrinsic stability, excellent oxygen reduction capabilities, and low toxicity. It also exhibits antimalarial and anticancer properties.Formula:C10H10FeColor and Shape:SolidMolecular weight:186.03Menoctone
CAS:Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.Formula:C24H32O3Color and Shape:SolidMolecular weight:368.51LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formula:C22H15N7Color and Shape:SolidMolecular weight:377.40Ipronidazole
CAS:Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.Formula:C7H11N3O2Color and Shape:SolidMolecular weight:169.182-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
CAS:Formula:C27H22Cl2N4Purity:98%Color and Shape:SolidMolecular weight:473.3964Chloroquine diphosphate
CAS:Controlled ProductChloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Chloroquine i a schizonticidal agent and is a widely prescribed antimalarial compound. The antiviral activity of chloroquine in vitro has been reported in 1960’s and recent publications have brought attention to its possible benefits in the treatment of COVID-19 patients, infected with the newly emerged coronavirus (SARS-CoV-2). Current evidence shows that chloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the S-glycoprotein.
Formula:C18H32ClN3O8P2Color and Shape:White Off-White PowderMolecular weight:515.86 g/molRef: 3D-FC20382
Discontinued productMebendazole
CAS:Mebendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating intestinal worm infections like threadworms and roundworms.
Formula:C16H13N3O3Purity:99.0 To 101.0%Color and Shape:PowderMolecular weight:295.29 g/molChloroquine sulfate
CAS:Anti-malarial quinine analogue; effective against Covid-19 infection in vitro
Formula:C18H28ClN3O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:417.95 g/molRef: 3D-FC171615
Discontinued productFlubendazole
CAS:Flubendazole is a benzimidazole anthelmintic with action on microtubule formation in parasites and is used for treating intestinal worms in humans and animals.
Formula:C16H12FN3O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:313.28 g/molRef: 3D-FF23317
Discontinued productLevamisole HCl - Bio-X ™
CAS:Levamisole is a synthetic imidazothiazole derivative belonging to the family of anthelmintic drugs. It is a nicotinic acetylcholine receptor (nAChR) agonists that binds to nAChRs on the neuromuscular junctions of parasitic worms, mimicking the action of the neurotransmitter acetylcholine. This excessive stimulation of nAChRs leads to persistent depolarization of muscle cells and spastic paralysis to expel of the worms. Levamisole exhibits broad-spectrum activity against various roundworms, whipworms, hookworms, and threadworms.
Formula:C11H12N2S·HClPurity:Min. 98.0%Color and Shape:PowderMolecular weight:240.75 g/molAmopyroquine
CAS:Amopyroquine is an antimalarial agent and is used for the treatment of malaria. Its mode of action involves the inhibition of haem polymerase in the parasite, leading to the accumulation of toxic haem
Formula:C20H20ClN3OPurity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:353.85 g/molSatranidazole
CAS:Satranidazole is an antimicrobial agent that falls under the category of synthetic nitroimidazoles. It is derived from chemical synthesis and is designed to combat infections caused by specific organisms. The mode of action involves the reduction of the nitro group within the organism, creating reactive intermediates that disrupt DNA synthesis and lead to cell death. This mode of action is notably effective against protozoal infections and anaerobic bacterial infections.
Formula:C8H11N5O5SPurity:Min. 95%Molecular weight:289.27 g/molInsecticidal agent 6
CAS:Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.
Formula:C19H14BrCl2N5O4Purity:98%Color and Shape:SolidMolecular weight:527.16
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