Protacs and Impurities

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products per page. 259 products on this category.

Product data	Purity	Price range	Estimated delivery
Thalidomide-NH-CBP/p300 ligand 2 REF: TM-T40142CAS: 2484739-21-9	- - -	To inquire	Tue 03 Dec 24
PZ703b REF: TM-T40135CAS: 2471970-56-4	- - -	1,435.00 €	Tue 03 Dec 24
PROTAC IDO1 Degrader-1 REF: TM-T37329CAS: 2488851-89-2	- - -	652.00 €	Tue 03 Dec 24
KTX-582 REF: TM-T74664CAS: 2573298-13-0	- - -	To inquire	Tue 03 Dec 24
PROTAC BRD4 Degrader-10 REF: TM-T40073CAS: 2417370-49-9	- - -	To inquire	Tue 03 Dec 24
KTX-951 REF: TM-T74670CAS: 2573298-36-7	- - -	To inquire	Tue 03 Dec 24
SJ988497 REF: TM-T74994CAS: 2595365-41-4	- - -	To inquire	Tue 03 Dec 24
2413035-41-1 REF: TM-T8743CAS: 2413035-41-1	- - -	To inquire	Tue 03 Dec 24
XZ739 REF: TM-T39909CAS: 2365172-19-4	- - -	1,208.00 €~1,991.00 €	Tue 03 Dec 24
PROTAC EGFR degrader 2 REF: TM-T74333	- - -	To inquire	Tue 03 Dec 24
PROTAC PD-1/PD-L1 degrader-1 REF: TM-T40112CAS: 2447066-37-5	- - -	237.00 €~3,483.00 €	Tue 03 Dec 24
NJH-2-056 REF: TM-T74277	- - -	To inquire	Tue 03 Dec 24
PROTAC ERRα Degrader-3 REF: TM-T39837CAS: 2306388-65-6	- - -	To inquire	Tue 03 Dec 24
XL01126 REF: TM-T74638	- - -	To inquire	Tue 03 Dec 24
HDAC6 degrader-3 REF: TM-T75018CAS: 2785404-83-1	- - -	To inquire	Tue 03 Dec 24
DSPE-PEG4-DBCO REF: TM-T17859CAS: 2112738-14-2	≥98%	83.00 €~1,746.00 €	Tue 03 Dec 24
Biotin-PEG8-amine REF: TM-T17595CAS: 2183447-27-8	99.59%	To inquire	Tue 03 Dec 24
dBRD9 REF: TM-T31221CAS: 2170679-45-3	99.81%	127.00 €~1,791.00 €	Tue 03 Dec 24
ZXH-3-26 REF: TM-T17297CAS: 2243076-67-5	98.90% - 98.90%	To inquire	Tue 03 Dec 24
AD4 REF: TM-T78805CAS: 2918262-09-4	98%	To inquire	Tue 03 Dec 24

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Thalidomide-NH-CBP/p300 ligand 2

CAS:2484739-21-9

Thalidomide-NH-CBP/p300 ligand 2 (P-007) is a PROTAC-based compound designed to degrade CBP and p300, acting …

Formula:

C₄₈H₅₇F₂N₁₁O₆

Color and Shape:

Solid

Molecular weight:

922.052

Ref: TM-T40142

5mg		823.00 €
10mg		1,284.00 €
50mg		To inquire
100mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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PZ703b

CAS:2471970-56-4

PZ703b is a novel BCL-XL PROTAC degrader with enhanced BCL-2 inhibition.

Formula:

C₈₀H₁₀₂ClF₃N₁₀O₁₁S₄

Color and Shape:

Solid

Molecular weight:

1600.44

Ref: TM-T40135

25mg 1,435.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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PROTAC IDO1 Degrader-1

CAS:2488851-89-2

First potent PROTAC IDO1 degrader; links IDO1 to CRBN E3 ligase for UPS-induced degradation (DC50=2.84 …

Formula:

C₄₀H₅₃BrFN₉O₁₃

Color and Shape:

Liquid

Molecular weight:

966.816

Ref: TM-T37329

5mg 652.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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KTX-582

CAS:2573298-13-0

KTX-582: potent IRAK4/Ikaros degrader (DC50=4/5nM), induces MYD88 MT DLBCL apoptosis & tumor regression in lymphoma.

Formula:

C₄₅H₅₁F₃N₈O₇

Color and Shape:

Liquid

Molecular weight:

872.93

Ref: TM-T74664

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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PROTAC BRD4 Degrader-10

CAS:2417370-49-9

Compound 8b, a dual-ligand PROTAC, targets VHL & BRD4, degrades BRD4 in PC3 cells; conjugates …

Formula:

C₅₉H₇₁F₂N₉O₁₅S₄

Color and Shape:

Solid

Molecular weight:

1312.5

Ref: TM-T40073

100mg		To inquire
500mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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KTX-951

CAS:2573298-36-7

KTX-951, a PROTAC, degrades IRAK4 (DC50=18 nM), 22% oral bioavailability in rats, shows promise as …

Formula:

C₄₆H₅₂F₂N₈O₆

Color and Shape:

Liquid

Molecular weight:

850.95

Ref: TM-T74670

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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SJ988497

CAS:2595365-41-4

SJ988497: PROTAC JAK2 degrader, inhibits CRLF2r cell growth, degrades GSPT1, combines Ruxolitinib, linker, Pomalidomide; researched …

Formula:

C₃₆H₃₆N₁₀O₅

Color and Shape:

Liquid

Molecular weight:

688.74

Ref: TM-T74994

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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2413035-41-1

CAS:2413035-41-1

2413035-41-1 is a useful organic compound for research related to life sciences. The catalog number …

Formula:

C₅₁H₅₇F₂N₉O₇S₂

Color and Shape:

Solid

Molecular weight:

1010.19

Ref: TM-T8743

Undefined size To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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XZ739

CAS:2365172-19-4

XZ739: Cereblon-based PROTAC, degrades BCL-XL (DC50 2.5 nM in MOLT-4, 16hr), induces caspase apoptosis.

Formula:

C₆₅H₇₆ClF₃N₈O₁₂S₃

Color and Shape:

Solid

Molecular weight:

1349.99

Ref: TM-T39909

5mg		1,208.00 €
10mg		1,991.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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PROTAC EGFR degrader 2

Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for …

Formula:

C₅₈H₇₂ClFN₁₂O₈S

Color and Shape:

Liquid

Molecular weight:

1151.78

Ref: TM-T74333

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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PROTAC PD-1/PD-L1 degrader-1

CAS:2447066-37-5

PROTAC PD-1/PD-L1 degrader-1, a Cereblon-based inhibitor, blocks PD-1/PD-L1 with 39.2 nM IC50, boosting immune response …

Formula:

C₅₉H₅₈ClN₇O₁₁

Color and Shape:

Solid

Molecular weight:

1076.59

Ref: TM-T40112

1mg		237.00 €
5mg		578.00 €
10mg		922.00 €
25mg		1,420.00 €
50mg		1,849.00 €
100mg		2,587.00 €
200mg		3,483.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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NJH-2-056

NJH-2-056: DUBTAC connecting OTUB1 with CFTR aid lumacaftor for cystic fibrosis study.

Formula:

C₄₁H₄₀F₂N₆O₈

Color and Shape:

Liquid

Molecular weight:

782.79

Ref: TM-T74277

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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PROTAC ERRα Degrader-3

CAS:2306388-65-6

PROTAC ERRα Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades …

Formula:

C₄₇H₅₀F₆N₆O₇S

Color and Shape:

Solid

Molecular weight:

957.0

Ref: TM-T39837

5mg		235.00 €
10mg		376.00 €
25mg		744.00 €
50mg		1,123.00 €
100mg		To inquire
200mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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XL01126

XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding …

Formula:

C₅₀H₆₄ClFN₁₀O₆S₂

Color and Shape:

Liquid

Molecular weight:

1019.69

Ref: TM-T74638

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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HDAC6 degrader-3

CAS:2785404-83-1

HDAC6 degrader-3: potent, selective, degrades HDAC6 at 19.4 nM, weakens HDAC1 at 0.647 μM, induces …

Formula:

C₄₁H₄₁F₄N₇O₁₁

Color and Shape:

Liquid

Molecular weight:

883.8

Ref: TM-T75018

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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DSPE-PEG4-DBCO

CAS:2112738-14-2

DSPE-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming …

Formula:

C₇₁H₁₁₆N₃O₁₅P

Purity:

≥98%

Color and Shape:

Solid

Molecular weight:

1282.67

Ref: TM-T17859

1mg		83.00 €
5mg		170.00 €
10mg		249.00 €
25mg		417.00 €
50mg		616.00 €
100mg		879.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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Biotin-PEG8-amine

CAS:2183447-27-8

Biotin-PEG8-amine is a biotinylated, polyethylene glycol (PEG)-derived linker utilized for the fabrication of proteolysis-targeting chimeras …

Formula:

C₂₈H₅₄N₄O₁₀S

Purity:

99.59%

Color and Shape:

Solid

Molecular weight:

638.81

Ref: TM-T17595

10mg		35.00 €
25mg		49.00 €
50mg		69.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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dBRD9

CAS:2170679-45-3

dBRD9 is a PROTAC.

Formula:

C₄₀H₄₅N₇O₁₀

Purity:

99.81%

Color and Shape:

Solid

Molecular weight:

783.83

Ref: TM-T31221

1mg		127.00 €
5mg		306.00 €
10mg		491.00 €
25mg		854.00 €
50mg		1,296.00 €
100mg		1,791.00 €
1mL*10mM (DMSO)		432.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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ZXH-3-26

CAS:2243076-67-5

ZXH-3-26 is a PROTAC composed of a Cereblon ligand, an E3 ubiquitin ligase, and a …

Formula:

C₃₈H₃₇ClN₈O₇S

Purity:

98.90% - 98.90%

Color and Shape:

Solid

Molecular weight:

785.27

Ref: TM-T17297

1mg 209.00 €

Estimated delivery in United States, on Tuesday 3 Dec 2024

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AD4

CAS:2918262-09-4

AD4, an artemisinin derivative functioning as a proteolytic targeting chimera (PROTAC) for PCLAF, effectively degrades …

Formula:

C₅₅H₇₈N₄O₁₅

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

1035.23

Ref: TM-T78805

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Tuesday 3 Dec 2024

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