Protacs and Impurities
MD-224
CAS:2136247-12-4
MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) …
Formula:
C48H43Cl2FN6O6
Purity:
100% - 99.07%
Color and Shape:
Solid
Molecular weight:
889.8
Ref: TM-T11980
1mg | 69.00 € | ||
5mg | 149.00 € | ||
10mg | 270.00 € | ||
25mg | 499.00 € | ||
50mg | 724.00 € | ||
1mL*10mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MT-802
CAS:2231744-29-7
MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has …
Formula:
C41H41N9O8
Purity:
95.93% - 97.00%
Color and Shape:
Solid
Molecular weight:
787.82
Ref: TM-T16157
1mg | 93.00 € | ||
5mg | 181.00 € | ||
10mg | 273.00 € | ||
25mg | 519.00 € | ||
50mg | 703.00 € | ||
100mg | 903.00 € | ||
200mg | 1,272.00 € | ||
1mL*10mM (DMSO) | 236.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Homo-PROTAC pVHL30 degrader 1
CAS:2244684-49-7
Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.
Formula:
C58H82N8O14S2
Purity:
98.95%
Color and Shape:
Solid
Molecular weight:
1179.45
Ref: TM-T13722
1mg | 55.00 € | ||
5mg | 125.00 € | ||
10mg | 159.00 € | ||
25mg | 308.00 € | ||
50mg | 496.00 € | ||
100mg | 722.00 € | ||
1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MS4078
CAS:2229036-62-6
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, …
Formula:
C45H52ClN9O8S
Purity:
98.74%
Color and Shape:
Solid
Molecular weight:
914.47
Ref: TM-T16153
1mg | 52.00 € | ||
2mg | 69.00 € | ||
5mg | 94.00 € | ||
10mg | 158.00 € | ||
25mg | 270.00 € | ||
50mg | 432.00 € | ||
100mg | 638.00 € | ||
1mL*10mM (DMSO) | 160.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
PROTAC sEH-degrader-1
sEH-degrader-1 (Compound 8) acts as an effective inhibitor of sEH, exhibiting IC50 values of 3.8 …
Formula:
C53H65F3N8O9
Color and Shape:
Liquid
Molecular weight:
1015.13
Ref: TM-T200366
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PTOTAC HSD17B13 degrader 1
CAS:3046195-01-8
PTOTAC HSD17B13 Degrader 1, a PROTAC designed to target 17β-HSD 13 (HSD17B13), incorporates several key …
Formula:
C45H45ClF3N7O5
Color and Shape:
Liquid
Molecular weight:
856.33
Ref: TM-T89855
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
SMART1
SMART1 is a CRBN-dependent PROTAC with high specificity that effectively degrades Smurf1. It inhibits tumor …
Formula:
C40H35N9O7
Color and Shape:
Liquid
Molecular weight:
753.76
Ref: TM-T89879
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
dCE-2
dCE-2, a PROTAC compound, specifically targets CBP/EP300. It comprises several key components: the E3 ubiquitin …
Formula:
C44H47N9O6
Color and Shape:
Liquid
Molecular weight:
797.9
Ref: TM-T200309
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
XD2-149
CAS:2710221-08-0
XD2-149 is a PROTAC compound designed to target STAT3. It is composed of the PROTAC …
Formula:
C38H39N5O8
Color and Shape:
Liquid
Molecular weight:
693.75
Ref: TM-T200304
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
L18I
L18I is a PROTAC (Proteolysis Targeting Chimera) that targets Btk to mitigate inflammation in autoimmune …
Formula:
C47H51N11O8
Color and Shape:
Liquid
Molecular weight:
897.98
Ref: TM-T200405
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PROTAC ACC degrader-1
PROTAC ACC degrader-1 (Compound 9b), an Acetyl-CoA Carboxylase degrader, demonstrates remarkable effectiveness, with a potent …
Formula:
C37H42N4O8
Color and Shape:
Liquid
Molecular weight:
670.75
Ref: TM-T200164
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
NH2-PEG2-C6-Cl hydrochloride
CAS:1035373-85-3
NH2-PEG2-C6-Cl hydrochloride is a PROTAC linker belonging to the PEG class and can be used …
Formula:
C10H23Cl2NO2
Color and Shape:
Liquid
Molecular weight:
260.2
Ref: TM-T40858L
10mg | 45.00 € | ||
25mg | 62.00 € | ||
50mg | 88.00 € | ||
100mg | 113.00 € | ||
500mg | 260.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Biotin-PEG4-Picolyl azide
CAS:2222687-71-8
Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used to synthesize PROTAC molecules.
Formula:
C27H42N8O7S
Purity:
97.71%
Color and Shape:
Solid
Molecular weight:
622.74
Ref: TM-T17587
1mg | 104.00 € | ||
5mg | 253.00 € | ||
10mg | 407.00 € | ||
25mg | 646.00 € | ||
50mg | 898.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
SJF620 hydrochloride
CAS:2821938-05-8
SJF620 hydrochloride is a PROTAC that utilizes a lenalidomide analog to recruit CRBN and ligands …
Formula:
C41H45ClN8O7
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
797.3
Ref: TM-T74002
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PROTAC TYK2 degradation agent1
CAS:2921556-14-9
PROTAC TYK2 Agent1 selectively degrades TYK2, with a 14 nM DC50, for autoimmune research.
Formula:
C55H69N13O7S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1056.28
Ref: TM-T75026
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
α1A-AR Degrader 9c
CAS:2863635-02-1
α1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the α1A adrenergic …
Formula:
C38H43N11O11
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
829.82
Ref: TM-T74557
5mg | 887.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PROTAC CDK9 degrader-5
CAS:2935587-89-4
PROTAC CDK9 degrader-5 selectively degrades CDK9 isoforms 42, 55 with DC50 of 0.10μM, 0.14μM via …
Formula:
C42H48Cl2N8O9
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
879.78
Ref: TM-T74851
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PF15
CAS:2892631-70-6
PF15, a PROTAC for FLT3-ITD, degrades FLT3 kinase. DC50: 76.7 nM; hinders FLT3-ITD+ cell growth; …
Formula:
C44H49N13O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
855.94
Ref: TM-T74259
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
MS9449
CAS:2772612-96-9
MS9449 is a powerful EGFR PROTAC; Kd: 17 nM (WT), 10 nM (L858R); targets mutant …
Formula:
C60H76ClFN10O8S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1151.82
Ref: TM-T74635
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
mPEG-DSPE sodium
CAS:247925-28-6
mPEG-DSPE sodium (DSPE-mPEG2000 sodium) is a PROTAC linker belonging to PEG and is involved in …
Formula:
C45H87NNaO11P
Color and Shape:
Liquid
Molecular weight:
2808.74
Ref: TM-T73740
5mg | 47.00 € | ||
10mg | 70.00 € | ||
25mg | 126.00 € | ||
50mg | 201.00 € | ||
100mg | 318.00 € | ||
500mg | 742.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024