Flavonoids

<p>Isoaloeresin D is a natural compound product, which is derived from the Aloe plant, specifically containing up to 20% Aloeresin D. It is a phytochemical extracted from the leaves of Aloe species, renowned for its inclusion of various bioactive compounds. The primary mode of action of Isoaloeresin D involves its potential antioxidant properties, which may contribute to the neutralization of free radicals and reduction of oxidative stress within biological systems.</p>

<p>7-O-Methyl-liquiritigenin is a flavonoid that has been shown to have anticarcinogenic properties. It has been studied in human studies and shown to be safe for use in cancer patients. 7-O-Methyl-liquiritigenin inhibits the growth of cancer cells by inhibiting cell proliferation, inducing apoptosis, and arresting the cell cycle at G2/M phase. 7-O-Methyl-liquiritigenin also inhibits the production of cyclooxygenase 2 (COX2) and prostaglandin E2 (PGE2), which have been linked to tumor promotion. 7-O-Methyl-liquiritigenin has been shown to inhibit the growth of human colon cancer cells in vitro, as well as in vivo when injected into mice. This compound also inhibits PIM1, an oncogene that regulates cellular proliferation, differentiation, tumor progression, angiogenesis, and metast</p>

<p>Izalpinin is a specialized phytochemical compound, specifically a flavonoid, which is derived from various plant sources. It exhibits a range of bioactive properties due to its complex chemical structure. The primary mode of action of Izalpinin involves modulation of cellular signaling pathways and inhibition of specific enzymatic activities, which underpins its diverse pharmacological effects.</p>

<p>3',5'-Diprenylliquiritigenin is a prenylated flavonoid, which is a type of naturally occurring compound found in certain plants. This specific compound is isolated primarily from licorice root, where it is synthesized as part of the plant's secondary metabolites. Its mode of action involves modulating various signaling pathways within biological systems, demonstrating potential antioxidant, anti-inflammatory, and anti-cancer properties.</p>

<p>4'-Hydroxy-7-methoxyisoflavan is a naturally occurring isoflavan, which is a subclass of flavonoids typically found in legumes and various plant sources. This compound is derived from the phenylpropanoid pathway, a critical biosynthetic route in plants responsible for producing a variety of phenolic compounds. Its mode of action is largely attributed to its ability to interact with cellular signaling pathways, exhibiting antioxidant, anti-inflammatory, and potentially estrogenic activities. These properties allow 4'-Hydroxy-7-methoxyisoflavan to modulate oxidative stress by scavenging free radicals and influencing gene expression related to detoxification enzymes.</p>

<p>Please enquire for more information about Rothindin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Puerarin is a bioactive isoflavone, which is extracted from the root of Pueraria lobata, commonly known as kudzu. It functions as a phytoestrogen and exhibits multiple pharmacological activities. The mode of action of puerarin involves interacting with various biological pathways, including antioxidant, anti-inflammatory, and neuroprotective mechanisms. It modulates enzyme activities and influences cell signaling pathways, making it a versatile compound for therapeutic research.</p>

<p>Morin hydrate is a flavonoid compound, which is a naturally occurring substance found primarily in the members of the Moraceae family, such as morus or mulberry and other fruits. It possesses significant antioxidant activity, which is achieved through its ability to scavenge free radicals and inhibit oxidative stress pathways. This mechanism of action is primarily due to its capacity to donate hydrogen atoms, thereby neutralizing unstable and reactive oxidative species.</p>

<p>8-Prenylnaringenin is a flavonoid compound, which is a naturally occurring phytoestrogen. It is primarily found in hops (Humulus lupulus), a plant commonly used in brewing beer. The compound is known for its high estrogenic activity, which is attributed to its ability to bind to estrogen receptors, particularly the estrogen receptor alpha.</p>

<p>5-Hydroxy-7-methoxyisoflavone is an isoflavone compound, a type of naturally occurring organic substance usually derived from plant sources such as soybeans and other legumes. These compounds are known for their significant role in the plant kingdom, often contributing to the plant's resistance against pathogens and environmental stresses. The mode of action of 5-Hydroxy-7-methoxyisoflavone involves its potential antioxidant properties, where it may neutralize free radicals, thereby reducing oxidative stress and cellular damage. This activity arises primarily from its chemical structure, enabling it to donate electrons to unstable molecules.</p>

<p>Quercetin-3-O-beta-D-glucopyranosyl-6-acetate is a glycosylated flavonoid compound, which is a naturally occurring plant metabolite. This compound is predominantly sourced from various plant species, where it acts as a secondary metabolite contributing to plant defense mechanisms. The mode of action of Quercetin-3-O-beta-D-glucopyranosyl-6-acetate involves its ability to function as an antioxidant, scavenging free radicals and reducing oxidative stress in biological systems. Additionally, its glycosylated structure may enhance its solubility and stability, facilitating better bioavailability compared to non-glycosylated counterparts.</p>

<p>5-Hydroxyflavanone is a naturally occurring flavonoid compound, which is predominantly sourced from various plant species, including fruits, vegetables, and certain herbs. These plants synthesize flavonoids as part of their secondary metabolism, aiding in defense mechanisms against pathogens and contributing to their pigmentation.</p>

<p>Rhodiosin is a bioactive compound, which is a polyphenolic glycoside derived from the plant Rhodiola rosea. This compound is primarily sourced through extraction processes that isolate active constituents from the roots of Rhodiola, a perennial plant native to cold regions and known for its traditional medicinal uses. Rhodiosin exhibits its mode of action through various molecular pathways, particularly influencing the central nervous system and enhancing cellular resistance to stress. It acts as an adaptogen, a class of metabolic regulators that promote homeostasis and increase the body's resilience to environmental and physical stressors.</p>

<p>Dihydrogenistein 4'-methyl ether is a phytoestrogen compound, which is derived from botanical sources such as Leguminosae plants. Its molecular structure consists of a flavonoid backbone, specifically modified with a methyl ether group at the 4' position. This structural modification imparts unique biological properties to the compound.</p>

<p>Flavanomarein is a flavonoid compound, which is derived from the tea plant, Camellia sinensis. This compound is part of the broader family of polyphenolic flavonoids, which are secondary metabolites commonly found in various plants. Flavanomarein exerts its effects primarily through its antioxidant properties. The flavonoid can scavenge free radicals and inhibit oxidative stress, which are critical functions in preventing cellular damage and maintaining homeostasis. Additionally, flavanomarein may modulate various signaling pathways that are involved in inflammation and apoptosis, offering potential therapeutic benefits.</p>

<p>Dihydrogenistein - decarboxy-dihydroxygenistein mixture is a synthetic biochemical compound, which is derived from the modification of isoflavonoid structures primarily sourced from plants. This mixture represents a complex amalgamation of two chemically altered forms of natural phytoestrogens. It functions by interacting with various cellular pathways, potentially influencing gene expression and signaling mechanisms through selective modulation of estrogen receptors and related enzymatic activities.</p>

<p>Hesperetin 7-O-beta-D-glucuronide is a flavonoid metabolite, which is a derivative of hesperetin commonly found in citrus fruits. This compound is produced through the biotransformation of hesperetin, involving conjugation with glucuronic acid in the liver, and is integral to the metabolism of flavonoids in humans. Hesperetin 7-O-beta-D-glucuronide exhibits potential antioxidant properties, making it of interest in scientific research aimed at exploring its bioactivity and potential therapeutic benefits.</p>

<p>Scutellarein-7-O-glucoside is a flavonoid glucoside, which is a type of phenolic compound commonly found in plants. This compound is primarily sourced from the Scutellaria species, among other botanical sources, where it occurs as a glycoside derivative of scutellarein. It serves a vital role in plant defense mechanisms, contributing to resistance against pathogens and ultraviolet radiation.</p>

<p>Isogentisin is a specific type of biochemical compound that falls under the category of xanthones, which are naturally occurring polyphenolic compounds. It is typically sourced from certain medicinal plants, where it is found in the roots or other plant parts. The mode of action of isogentisin is primarily related to its antioxidant properties, which involve neutralizing free radicals and reducing oxidative stress within biological systems. This action can potentially protect cells and tissues from damage that may lead to various diseases.</p>

<p>Apigenin - 94% is a purified form of apigenin, which is a naturally occurring flavonoid. It is primarily sourced from various plant species, including parsley, celery, and chamomile, where it is a prominent active component. The mode of action of apigenin involves multiple biochemical pathways: it acts as an anti-inflammatory agent, modulates enzyme activities, and exhibits antioxidant properties by scavenging free radicals. Additionally, apigenin interacts with cellular signaling pathways, such as the MAPK and PI3K/Akt, which contribute to its protective effects against oxidative stress and its potential in promoting apoptosis in cancerous cells.</p>

<p>Tamarixetin-7-O-rutinoside is a flavonoid glycoside, which is a natural compound derived from the Tamarix plant. In nature, it is typically isolated from species within this genus, known for its phytoactive compounds. Tamarixetin-7-O-rutinoside acts primarily through its antioxidant mechanism, which involves scavenging free radicals and reducing oxidative stress within biological systems. This activity is crucial in minimizing cellular damage and maintaining homeostasis.</p>

<p>4,7-Dihydroxy-2'-methoxyisoflavan is a naturally occurring isoflavan compound, which is typically extracted from various plant sources known for their medicinal properties. These sources include legumes and other plant families rich in phytoestrogens and related secondary metabolites.</p>

<p>Hesperidin is a bioflavonoid compound, which is naturally sourced from citrus fruits, primarily found in the peels of oranges and lemons. Its mode of action involves acting as a potent antioxidant by scavenging free radicals and reducing oxidative stress. Hesperidin also exhibits anti-inflammatory effects by modulating various signaling pathways and inhibiting the release of pro-inflammatory cytokines.In scientific applications, hesperidin is extensively studied for its potential therapeutic benefits. Its antioxidant properties make it a candidate for mitigating oxidative damage in various tissues, while its anti-inflammatory effects are explored in the context of chronic inflammatory conditions. Research has shown potential cardiovascular benefits, including the improvement of endothelial function and lipid profiles. Additionally, hesperidin is investigated for its neuroprotective effects and potential in managing metabolic disorders. These diverse applications highlight the significance of hesperidin in pharmacological research, aiming to leverage its natural properties for health benefits.</p>

<p>Tectorigenin is a naturally occurring isoflavone, which is derived from plants such as Belamcanda chinensis and the Pueraria genus. It functions primarily as an antioxidant and has demonstrated various biological activities. Tectorigenin acts by inhibiting certain enzymes and signaling pathways, which contributes to its anti-inflammatory, anti-cancer, and neuroprotective effects.</p>

<p>Scutellarein 7-methyl ether is a naturally occurring flavone derivative, which is primarily sourced from various plant species within the genus Scutellaria. These plants are rich in flavonoids and have been studied extensively for their diverse biochemical properties. The mode of action of Scutellarein 7-methyl ether involves its ability to act as an antioxidant, neutralizing free radicals and reducing oxidative stress at the cellular level. This compound has been observed to interfere with various enzymatic pathways, contributing to its potential therapeutic effects.</p>

<p>8-Hydroxygenistein-5,7,8,4'-tetramethyl ether is a natural product with bioactive properties. It is an 8-hydroxy derivative of genistein that is found in soybeans and other legumes. The purity of this compound is confirmed by HPLC standards and it has been isolated from the plant source. This compound can be used as a reference material for analytical purposes or for quality control testing.</p>

<p>Orobol 7,3'-dimethyl ether is a flavonoid compound, which is derived from natural plant sources. This compound is synthesized as a methylated ether of Orobol, a type of isoflavone. The mode of action of Orobol 7,3'-dimethyl ether involves interacting with biological pathways that may influence cellular processes, including antioxidant and anti-inflammatory activities. By modulating these pathways, it potentially impacts various physiological functions.</p>

<p>Naringin dihydrate is a flavonoid glycoside, which is a bioactive compound found primarily in citrus fruits, especially grapefruits and oranges. It acts as a potent antioxidant and anti-inflammatory agent, which functions by scavenging free radicals and modulating signaling pathways involved in oxidative stress and inflammation.</p>

Natural glycoside

<p>Aureusidin is a flavonoid pigment, which is a type of plant-derived compound. It is primarily sourced from various flowering plants, where it contributes to the coloration of petals. Aureusidin is synthesized through the enzymatic oxidation of chalcones, which involves flavonoid oxidase activity.</p>

<p>Applications Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.<br>References Shulan S. et al.: Am. J. Chin. Med., 38, 777 (2010); Huang, X. et al.: J. Chrom. B. Anal. Tech. Biomed. Life Sci., 962, 75 (2014);<br></p>

<p>Applications O-Methylated metabolite of the flavanoid Quercertin (Q509500) with antioxidant activity.<br>References Soobrattee, M.A. et al.: Mut. Res. Fund. Mol. Mech. Mutagen., 579, 200 (2005); Yamamoto, N. et al.: Arch. Biochem. Biophys., 372, 347 (1999);<br></p>

<p>Applications 5α-Pregnane-3-one-20α-ol, is a steroid metabolome, that can be used for in studies of a possible tool for laboratory diagnosis of schizophrenia. It is also a metabolite of Progesterone (P755900) in adipose cells.<br>References Bicikova, M., et al.: J. Steriod Biochem. Mol. Bio., 77, 133 (2013); Zhang, Y., et al.: Mol. Cell. Endocrinology, 298, 76 (2009);<br></p>

<p>Applications 8,9-Di-O-methyl-urolithin D is a derivative of Urolithin D (U847020) which is used in biological studies to evaluate DNA gyrase inhibitory activity of ellagic acid derivatives.<br>References Weidner-Weels, M. A., et al: Bioorg. Med. Chem. Lett., 8, 97 (1998)<br></p>

<p>rac-Tetrahydrodaidzein is a racemic compound, which is a mixture of two enantiomers. It is derived from the reduction of the isoflavone daidzein, primarily found in soybeans and other legumes. This compound exhibits interesting pharmacological properties due to its ability to interact with estrogen receptors, functioning as a modulator of estrogenic activity. Its mode of action involves binding to these receptors, potentially influencing various estrogen-mediated physiological processes.</p>

<p>4'-O-Hexanoyldaidzein is a chemically modified isoflavone, which is a derivative of daidzein. This compound is sourced from soybeans, renowned for being rich in naturally occurring isoflavones. The modification entails the addition of a hexanoyl group to the daidzein molecule, altering its physicochemical properties and potentially enhancing its biological activity.</p>

<p>2',5,6',7-Tetraacetoxyflavanone is a flavanone derivative, which is a type of flavonoid compound primarily sourced from plants, particularly citrus fruits. Its structure consists of a flavanone backbone with acetoxy groups at specific positions, which may influence its biochemical activity. Flavanones like 2',5,6',7-Tetraacetoxyflavanone are of interest in the scientific community due to their potential biological activities, including antioxidant properties.</p>

<p>Euchrestaflavanone B is a naturally occurring flavonoid, which is a type of polyphenolic compound. It is primarily sourced from various plant species, particularly those found in the Leguminosae family. The mode of action of Euchrestaflavanone B involves its interaction with cellular signaling pathways, where it exhibits a broad spectrum of bioactive effects. These include anti-inflammatory, antioxidant, and anticancer properties, potentially through modulation of enzyme activities and gene expression.</p>

<p>Sophoraflavanone I is a naturally occurring flavonoid compound, which is derived from the roots of the Sophora species, a genus of flowering plants in the family Fabaceae. This compound is predominantly extracted from the roots of Sophora flavescens, also known as Chinese Sophora.</p>

<p>3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone, (2R,3R)- is a prenylated flavonoid compound, which is a type of naturally occurring polyphenol. These compounds are known for their complex structures and biological activities, frequently contributing to the therapeutic properties of various plants. The source of this flavanone is often plants belonging to the Fabaceae family, including the roots and other parts of certain legumes, where it accumulates as part of the plant’s secondary metabolism.</p>

<p>Kaempferol-3-rutinoside-7-rhamnoside is a flavonoid glycoside, which is an organic compound derived from specific plant species like tea, onions, and broccoli. It primarily exists as a complex molecule formed by the bonding of kaempferol with sugar moieties—rutinoside and rhamnoside. This compound functions by modulating various cellular signaling pathways, including those involved in oxidation-reduction processes, apoptosis, and inflammation. It combats oxidative stress by scavenging free radicals, thereby providing a protective effect against cellular damage.</p>

<p>6,4'-Dihydroxy-5,7-dimethoxyflavanone is a naturally occurring flavanone, which is a type of polyphenolic compound commonly found in various plant species. These compounds are synthesized through plant secondary metabolic pathways and are typically located in fruits, flowers, and leaves, playing essential roles in plant defense and pigmentation.</p>

<p>6'-Prenylpiscidone is an isoflavone derivative, which is a class of polyphenolic compounds primarily found in plants, particularly legumes. It is sourced from natural botanical origins, often derived from specific species known for their rich isoflavone content. The mode of action of 6'-Prenylpiscidone involves interactions with cellular targets that may influence a variety of biological pathways. These pathways are often associated with antioxidant activity, modulation of enzyme function, and potential estrogenic or anti-estrogenic effects due to its structural similarity to estrogen hormones.</p>

<p>3'-Methoxydaidzein is an isoflavone compound, which is typically isolated from soybean sources. This compound belongs to a class of phytoestrogens, naturally occurring plant-derived compounds with estrogenic activity. 3'-Methoxydaidzein exhibits various biological activities due to its structural similarity to human estrogens, allowing it to bind to estrogen receptors. Its mode of action primarily involves modulating estrogen receptor activity, potentially influencing gene expression in estrogen-responsive tissues.</p>

<p>Sinocrassoside C1 is a cycloartane triterpenoid, which is a class of chemical compounds. It is derived from the plant genus Sinocrassula, known for its traditional medicinal applications. The mode of action of Sinocrassoside C1 involves interactions with specific cellular targets, potentially influencing signal transduction pathways and modulating enzyme activities. These interactions may account for its reported bioactivities, including anti-inflammatory, anti-tumor, and neuroprotective effects.</p>

<p>7-O-Ethyldaidzein is a synthetic flavonoid derivative, which is primarily sourced from modifications of the naturally occurring isoflavone daidzein. Daidzein itself is found in soy products and other legumes. Through a chemical process, 7-O-ethyl groups are introduced to enhance its biological activity.</p>

<p>7-Methoxyflavanone is a bioactive compound, specifically a methoxylated flavanone, which is derived from various plant sources. This compound plays a role in the modulation of several biological pathways due to its structural attributes. As a flavanone, it is known to interact with various cellular mechanisms including enzyme inhibition, receptor binding, and antioxidant activity. These interactions result in diverse pharmacological effects, such as anti-inflammatory and neuroprotective properties.</p>

<p>Sophoraflavanone H is a prenylated flavonoid, which is a natural compound isolated primarily from plants of the Sophora species. The source of this bioactive compound is predominantly the root extracts of these plants, which have been traditionally utilized in herbal medicine systems for their therapeutic properties.</p>

<p>Morin dihydrate is a flavonoid compound, which is a type of polyphenolic molecule. It is primarily sourced from the Moraceae family of plants, including mulberry leaves and certain fruits. As a flavonoid, Morin exerts its biochemical effects mainly through its capacity to scavenge free radicals, thus exhibiting significant antioxidant activity. This mode of action is attributed to its structure, which allows it to donate electrons and neutralize reactive oxygen species, consequently reducing oxidative stress at the cellular level.</p>

<p>Quercetin 3,7,4'-trimethylether is a flavonoid derivative, which is a naturally occurring compound. It is sourced from various plants where it acts as a secondary metabolite. Its mode of action involves the modulation of signaling pathways and the inhibition of certain enzymes. Specifically, it has demonstrated the ability to interfere with cellular processes fundamental to cancer progression, such as proliferation and apoptosis.</p>