Primary Antibodies

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008],

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008],

This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008],

Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure. All three HP1 family members (α, β, and γ) are primarily associated with centromeric heterochromatin.

ADAM metallopeptidase domain 28(ADAM28) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016],

This gene likely encodes a member of the complexin family. The encoded protein may be involved in synaptic vesicle exocytosis. [provided by RefSeq, Jan 2009],

This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016],

Chicken antibody, anti-Protein A:HRP conjugate concentrate, 1 ml. This antibody is part of the Protein A ELISA kit (F400, F400Z).

Affinity-purified rabbit antibody conjugated to HRP in a protein matrix with preservative, 12 ml.

Affinity-purified goat antibody to hIgM, conjugated to HRP in a protein matrix with preservative. Component of the Human Immunoglobulin M ELISA Kit (F170), 12 ml.

Affinity-purified goat anti-MRC5 HCP. This antibody is part of the MRC5 HCP ELISA Kit (F300).

Affinity-purified goat anti- P. pastoris HCP Antibody. This antibody is part of the P. pastoris 3G HCP ELISA Kit (F1015).

Goat anti-MDCK HCP affinity purified antibody. This antibody is part of the MDCK HCP ELISA Kit (F800).

Affinity-purified goat anti-PG13 HCP. This antibody is part of the PG13 Host Cell Protein ELISA Kit (F995).

For use in ELISA

Affinity-purified goat antibody to hIgA conjugated to HRP in a protein matrix with preservative. Component of the Human Immunoglobulin A ELISA Kit (F165), 12 ml.

Antibody Type: Rabbit Monoclonal
Application: ELISA,FCM,IF
Reactivity: Human

Antibody Type: Rabbit Monoclonal
Application: ELISA,FCM
Reactivity: Human

Chicken antibody conjugated to HRP in a protein matrix with preservative. Component in the Mix-N-Go™ Protein A ELISA Kits F600 and F610.

Anti-HEK 293:HRP labeled, 1 x 12 ml

Mouse monoclonal antibody conjugated to biotin in a protein matrix with preservative, 12 ml. Component of the Protein A ELISA Kit, F050H.

Affinity-purified goat anti-BHK HCP. This antibody is part of the BHK HCP ELISA Kit (F510).

Affinity-purified goat anti-NS/0 2G Antibody

Affinity-purified anti-Protein A:HRP Conjugate. This antibody is part of the Protein A ELISA Kit (F400).

Affinity-purified goat anti-SP2/0 HCP, 2G. This antibody supports the SP2/0 HCP ELISA kit, F1030.

Affinity-purified rabbit antibody conjugated to HRP in a protein matrix with preservative, 12 ml. Component of the Bovine Plasma Proteins (BPP) ELISA Kit (F290).

Goat Anti-BHK:HRP conjugate concentrate, 1 mg. This antibody is part of the BHK HCP ELISA Kit (F510).

Affinity-purified goat anti-A549 HCP

For use in Vero Cell, 2G ELISA (F975)

Affinity-purified goat anti-P. pastoris HCP antibody. This antibody is part of the Pichia pastoris HCP ELISA Kit (F140).

Affinity-purified goat anti-CHO Lysate HCP Antibody