
Backbone Sugars and Nucleobases
Found 1022 products of "Backbone Sugars and Nucleobases"
5-Chlorouracil
CAS:5-Chlorouracil is a drug that is used to treat cancer. It has been shown to have biological properties, and its mechanism of action is not yet fully understood. 5-Chlorouracil can be synthesized in the laboratory by reacting sodium hydroxide with 5-chloro-2,4(1H,3H)-pyrimidinedione. In wastewater treatment plants, it reacts with organic matter in the water to form nontoxic products, such as carbon dioxide and urea. The reaction solution contains 5-chlorouracil, which undergoes tautomerization spontaneously or through the addition of base. This reaction is reversible, and both the erythro and threo forms are present in solution at equilibrium. The biological properties of 5-chlorouracil have been investigated using sublethal doses in experimental animals. In one study, 5-chlorouracil was found to inhibit xanthine oxidase activity in rats significantly moreFormula:C4H3ClN2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:146.53 g/mol2-Mercaptopurine
CAS:2-Mercaptopurine (2MP) is a thiopurine drug that is used to treat bowel disease. 2MP inhibits the activity of methyltransferase, which is an enzyme that converts 6-mercaptopurine to 6-thioguanine. This process prevents the conversion of 6-thioguanine into 6-thiouric acid, which is an intermediate in the synthesis of thymine nucleotides. 2MP also inhibits the binding of atp-binding cassette transporter proteins to DNA and blocks the incorporation of purines into RNA and DNA. The drug has been shown to be effective in treating squamous cell carcinoma and other diseases with a high level of activity. 2MP has been shown to be metabolized by erythrocyte polymerase chain reaction and can be detected in biological samples.Formula:C5H4N4SPurity:Min. 95%Color and Shape:PowderMolecular weight:152.18 g/molN1-(Pivaloyloxy)methyl-N2-(dimethylamino)methylene 9-deazaguanine
CAS:Please enquire for more information about N1-(Pivaloyloxy)methyl-N2-(dimethylamino)methylene 9-deazaguanine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C15H21N5O3Purity:Min. 95%Molecular weight:319.36 g/mol3'-[2- Cyanoethyl N, N- bis(1- methylethyl) phosphoramidite]-5'- O- [bis(4- methoxyphenyl) phenylmethyl] - 2'- O- methyl- N- [2- [4- (1- methylethyl) phenoxy] acetyl] -guanosine
CAS:Please enquire for more information about 3'-[2- Cyanoethyl N, N- bis(1- methylethyl) phosphoramidite]-5'- O- [bis(4- methoxyphenyl) phenylmethyl] - 2'- O- methyl- N- [2- [4- (1- methylethyl) phenoxy] acetyl] -guanosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C52H62N7O10PPurity:Min. 95%Molecular weight:976.06 g/mol3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine
CAS:3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine (BDBMU) is a pyrimidine derivative that can be used as an antiviral drug. It inhibits the synthesis of DNA and RNA by inhibiting viral polymerase. BDBMU is a prodrug of uracil, which is converted to the active compound in tissues. The benzoylation reaction produces a fluorine atom at C5, which increases its potency. This drug has been shown to have minimal toxicity in tumor cells and has been used for the treatment of leukemia and other cancers.Formula:C17H17F3N2O5Purity:Min. 95%Molecular weight:386.32 g/mol(S)-HPMPA
CAS:(S)-HPMPA is a nucleotide analogue, which is a chemically synthesized compound designed to mimic nucleotides. It acts as both an antiviral and an antitumor agent, sourced primarily through synthetic chemistry involving the modification of naturally occurring nucleotide structures. The mode of action of (S)-HPMPA involves mimicking natural substrates of various viral polymerases and cellular enzymes, thereby inhibiting viral DNA synthesis and disrupting the replication cycle of DNA viruses. Additionally, it can interfere with certain cellular pathways contributing to its antitumor effects.Formula:C9H14N5O5PPurity:Min. 95%Molecular weight:303.21 g/mol4-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine
CAS:Formula:C5H5N5OPurity:>93.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystallineMolecular weight:151.13Isobutyryl Chloride
CAS:Formula:C4H7ClOPurity:>98.0%(GC)(T)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:106.552-Chloro-1,3,2-dioxaphospholane
CAS:Formula:C2H4ClO2PPurity:97%Color and Shape:LiquidMolecular weight:126.47871-Methyl-5-mercaptotetrazole
CAS:Formula:C2H4N4SPurity:97%Color and Shape:SolidMolecular weight:116.1450N,O-Bis(Trimethylsilyl)Acetamide
CAS:Formula:C8H21NOSi2Purity:95%Color and Shape:LiquidMolecular weight:203.42942-Chloro-1,3,2-dioxaphospholane-2-oxide
CAS:Formula:C2H4ClO3PPurity:95%Color and Shape:LiquidMolecular weight:142.47811-Phenyl-1H-Tetrazole-5-Thiol
CAS:Formula:C7H6N4SPurity:95%Color and Shape:SolidMolecular weight:178.21431-Methyl-3-nitro-1-nitrosoguanidine
CAS:Formula:C2H5N5O3Purity:95%Color and Shape:LiquidMolecular weight:147.0928N,N'-Dimethylformamide dimethyl acetal
CAS:Formula:C5H13NO2Purity:97%Color and Shape:LiquidMolecular weight:119.16225-(Ethylthio)-1H-tetrazole
CAS:Formula:C3H6N4SPurity:98%Color and Shape:SolidMolecular weight:130.1715Phosphorodiamidous acid, N,N,N',N'-tetrakis(1-methylethyl)-, 2-cyanoethyl ester
CAS:Formula:C15H32N3OPPurity:95%Color and Shape:LiquidMolecular weight:301.4078Ref: 4Z-G-2447
Discontinued productRef: 4Z-G-2434
Discontinued productSYBR GREEN II
CAS:1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity.
Formula:C28H28IN3OSPurity:98%Color and Shape:SolidMolecular weight:581.516-Azauracil
CAS:6-Azauracil is a heterocycle with the chemical formula C8H10N2O3. It is approved by the FDA to treat HIV infections and has been shown to have pharmacokinetic properties in humans. 6-Azauracil is structurally similar to uracil, which is found in RNA, but lacks the hydroxyl group on the para position of the heterocyclic ring. The synthesis of this drug was accomplished through acid complex formation with nucleotides and nitrous acid. The compound inhibits replication of retroviruses by competitive inhibition of primer binding. 6-Azauracil has also been shown to be toxic in rats, leading to congestive heart failure and death when administered at high doses. This drug may also act as an anti-inflammatory agent by inhibiting prostaglandin synthesis or platelet aggregation.
Formula:C3H3N3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:113.07 g/molTrityl Chloride Resin cross-linked with 1% DVB (200-400mesh) (2.0-2.5mmol/g)
Color and Shape:White to Amber powder to crystal




