Nucleosides

<p>4-(4-Fluorophenyl)pyrimidine-2-thiol is a monophosphate deoxyribonucleoside that has been modified to include an activator group. This modification allows for the phosphoramidite of 4-(4-Fluorophenyl)pyrimidine-2-thiol to be incorporated into DNA, which makes it a novel substance. The CAS number for 4-(4-Fluorophenyl)pyrimidine-2-thiol is 155957-43-0. 4-(4-Fluorophenyl)pyrimidine-2-thiol has shown anticancer activity in vitro and may have potential as a cancer chemotherapeutic agent.</p>

<p>Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Bromo-2'-deoxyadenosine cep is a modified nucleoside that is used in the treatment of cancer. It has been shown to be effective in treating leukemia, lymphoma and myeloma. 8-Bromo-2'-deoxyadenosine cep inhibits the growth of cells by inhibiting DNA synthesis through inhibition of deoxynucleotide biosynthesis. This drug also has antiviral activity against herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2) and human immunodeficiency virus type 1 (HIV1). 8-Bromo-2'-deoxyadenosine cep is a synthetic nucleoside that is phosphoramidite that can be used to synthesize DNA or RNA.</p>

<p>3'-Deoxy-N6-lauroyladenosine is a nucleoside analog that is used to treat cancer. It is a phosphoramidite compound and it has been shown to be highly active against cancer cells. 3'-Deoxy-N6-lauroyladenosine is an antiviral agent that inhibits viral DNA synthesis by competing with the natural substrate, deoxyribonucleosides, for incorporation into the growing DNA chain. It also prevents the replication of RNA viruses by inhibiting their transcription and translation processes. 3'-Deoxy-N6-lauroyladenosine also inhibits inflammation in the body and may act as a chemotherapeutic agent in other diseases such as diabetes, Alzheimer's disease, and Parkinson's disease.</p>

<p>3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine is a novel, activator, ribonucleosides, deoxyribonucleosides, diphosphate, phosphoramidites, modified nucleosides. It can be used as an anticancer and antiviral agent.</p>

<p>1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a monophosphate nucleotide that is used in antiviral therapy. It inhibits viral DNA synthesis by inhibiting viral DNA polymerase and viral RNA transcription. The drug is currently in phase I clinical trials for the treatment of cancer and AIDS. 1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a novel compound that has not been described in the literature before. The drug was synthesized by modifying a natural nucleoside, uracil, with fluorine to produce an antiviral agent. This compound has shown anticancer effects in vitro and in vivo experiments as well as antiplasmodial activity against malaria.</p>

<p>N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is a novel antiviral agent that exhibits high quality and high purity. It can be used to synthesize DNA, RNA, and other nucleosides. N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is an activator of the DNA polymerase and an inhibitor of the viral polymerase. This compound has been shown to have anticancer properties in vitro and in vivo.</p>

<p>N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine 3'-CE phosphoramidite is a novel, deoxyribonucleosides that has been synthesized with high purity, high quality, and high yield. It is an anticancer drug that inhibits the synthesis of ribonucleotides in DNA and RNA.</p>

<p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate lithium salt is an analog of ATP that has significant inhibitory effect on DNA polymerase. It inhibits the synthesis of RNA and protein by binding to the enzyme DNA gyrase. This drug is used in cell culture as a nucleotide analog to study how cells are affected by atp analogs. 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate lithium salt is used at high concentrations in vitro, where it inhibits topoisomerases and prevents cell division.</p>

<p>N4-Benzoyl-5'-O-DMT-(2'-O, 4'-C-methylene)-5-methyl-a-cytidine 3'-CE phosphoramidite is a novel modified nucleoside that has antiviral and anticancer properties. It is synthesized by reacting the 3'-hydroxyl group of cytidine with 2,4,6-trimethoxybenzoyl chloride to form N4-(2',6'-dimethoxyphenyl)benzoylcytidine. This compound is then reacted with methylene bis(diethylamino)thiophene (2') and the 5' phosphoramidite of 5'-O-DMT-(2'-O, 4'-C-methylene)-5-methylcytidine. The product is an active synthetic nucleoside that can be used as a building block for other nucleosides or oligonucleotides.</p>

<p>2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a novel nucleotide analog that exhibits anticancer activity. It has been shown to inhibit the growth of human leukemia cells and enhance the cytotoxic effect of doxorubicin. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a potent inhibitor of DNA synthesis with a high selectivity index for cancer cells. This agent inhibits DNA synthesis by competing with deoxyribonucleosides for incorporation into the growing DNA strand. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is an activator at the adenine phosphoribosyltransferase (APRT) enzyme and may also have an effect on ribonucleotide reductase (R</p>

<p>4'-a-C-Methylguanosine is a nucleoside that is synthesized by the condensation of 4'-amino-2',3'-dideoxyadenosine and 1,2-ethanediol. This product is an activator that can be used to synthesize novel DNA analogues with various chemical modifications. It has shown antiviral and anticancer activity in vitro. 4'-a-C-Methylguanosine was also found to be more active than guanosine when it came to inhibiting viral replication in human cells.</p>

<p>2-(2-Furyl)-5-pyrimidinecarbaldehyde (2FP) is a novel anticancer activator that belongs to the class of modified DNA. 2FP is a nucleoside analogue that inhibits the synthesis of DNA, RNA, and protein. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. This compound may be used as an antiviral agent against HIV and herpes virus infections. 2FP has high purity and quality, with CAS number 959240-19-8.</p>

<p>Benzoyl stavudine is a nucleoside that is used as an anti-HIV drug. It has been shown to be a prodrug of the active form, stavudine, by reductive elimination. Benzoyl stavudine has been shown to inhibit HIV replication by competitively binding to the viral reverse transcriptase enzyme and preventing the synthesis of RNA from DNA. This drug also inhibits ribonucleotide reductase, an enzyme that converts ribonucleotides into deoxyribonucleotides for DNA synthesis. This inhibition prevents the formation of new viral DNA and halts viral replication.</p>

<p>8-Aminoguanosine is a synthetic purine nucleoside that inhibits DNA synthesis. It has been shown to inhibit the proliferation of HL-60 cells, which are a model for human monocytes and neutrophils. 8-Aminoguanosine has been shown to bind to the template strand of DNA and inhibit the incorporation of deoxyribonucleotide triphosphates into the newly synthesized strand. This binding prevents DNA replication by preventing access to the template strand of DNA. 8-Aminoguanosine inhibits cyclin D2, an enzyme required for cell division, at concentrations as low as 0.1 mM, and it also inhibits microtubule assembly. 8-Aminoguanosine has shown in vitro activity against various tumor cell lines including Molt-4 and MCF7 cells, and in vivo activity in a mouse model against C3H/HeJ mice transplanted with Lewis lung carcinoma cells.</p>

<p>5-Aminoallyluridine 5'-triphosphate sodium salt is a modified nucleoside that has antiviral and anticancer activity. It is a prodrug of 5-aminoallyluridine and is activated by deoxyribonucleotide ribonucleotides in the cell. This drug also can be used as an activator for other drugs, such as cytosine arabinoside, which are inactive or less active when administered alone.</p>

<p>Please enquire for more information about 6-Azathymidine ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>P2Y receptor agonist; precursor in RNA biosynthesis</p>

<p>2,4,5,6-Tetraaminopyrimidine 2HCl is a chemical compound that belongs to the group of pyrimidines. It is a colorless solid with a melting point of 178.2°C and a boiling point of 339.8°C. This compound can be obtained by reacting 2,4,5-trichloropyrimidine with potassium cyanide in acetic acid solution or by heating 2,4-diaminopyrimidine with ammonium chloride and sodium nitrate in water.<br>In the liquid chromatography process this compound is used as an analytical reagent for determining the purity and identity of organic compounds by measuring their retention time on the column.</p>

<p>2',3'-Dideoxy-2',3'-didehydrocytidine (ddC) is a nucleoside analog that is used in the treatment of hepatitis B and C. This drug inhibits the reverse transcriptase enzyme and has cytostatic effects on viruses, for example, by preventing cell division. 2',3'-Dideoxy-2',3'-didehydrocytidine also inhibits viral replication by acting as an antigen and inducing antibody production. This drug binds to a variety of enzymes, including preparations of cellular enzymes, human immunodeficiency virus type 1 (HIV-1), and reverse transcriptase. The effective dose of ddC is 300 mg/day given orally.</p>