
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3567 products of "Nucleosides"
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2'-Deoxy-2'-fluorouridine-5'-monophosphate
CAS:<p>2'-Deoxy-2'-fluorouridine-5'-monophosphate is a novel anticancer drug that inhibits the proliferation of cancer cells. It is a phosphoramidite monophosphate nucleoside analog and is used in the synthesis of DNA. This product can be used as an antiviral agent against herpes simplex virus and influenza A by inhibiting viral DNA polymerase, as well as being used to treat HIV infection by inhibiting reverse transcriptase. 2'-Deoxy-2'-fluorouridine-5'-monophosphate can also be used to inhibit tumor growth by inhibiting the synthesis of deoxyribonucleosides and nucleotides, thereby preventing DNA replication.</p>Formula:C9H12FN2O8PPurity:Min. 95%Molecular weight:326.17 g/mol2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:<p>2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt is a nucleotide analog that has been shown to inhibit the synthesis of fatty acids and proteins, as well as cause depression in mice. It also has antiviral activity against the type strain of HIV-1 (HXB2). The drug inhibits protein synthesis by preventing the incorporation of amino acids into a growing polypeptide chain. This inhibition can be reversed by adding vitamin D3 or fatty acids. 2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt has been shown to have anti-cancer properties due to its ability to induce apoptosis, which is programmed cell death. This drug also has immune functions, such as an increase in natural killer cells and cytokines, as well as improving energy efficiency in the optical system.</p>Formula:C10H16N5O12P3S·xLiPurity:Min. 95%Molecular weight:523.25 g/molEthynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite
CAS:<p>Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite is a monophosphate nucleoside analog. The ethynyl group is attached to the 2'-hydroxyl group of the ribose sugar. This nucleotide analogue inhibits DNA and RNA synthesis by inhibiting DNA polymerase and RNA polymerase. Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite has antiviral activity against Herpes simplex virus type 1 (HSV1) and type 2 (HSV2) in vitro, as well as cytotoxic activity against human leukemia cells in vitro.</p>Formula:C37H45N2O6PPurity:Min. 95%Molecular weight:644.74 g/molGuanylyl-3'-5'-adenosine triethylammonium salt
CAS:<p>Guanylyl-3'-5'-adenosine triethylammonium salt (GAT) is a prodrug that is hydrolyzed in vivo to adenosine 3',5'-cyclic monophosphate (cAMP). GAT has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. GAT has also been used as a diagnostic tool for inflammatory bowel disease and infectious diseases of the bowel. It can be used as an adjuvant therapy for treating bowel disease, although it does not affect the course of the disease.</p>Formula:C20H25N10O11P·xC6H15NPurity:Min. 95%Color and Shape:PowderMolecular weight:612.45 g/mol5'-O-DMT-2'-O-propylphthalimidouridine
<p>5'-O-DMT-2'-O-propylphthalimidouridine is a synthetic nucleoside that has antiviral and anticancer properties. It is used as a precursor for the synthesis of other nucleosides, including uridine and cytidine. 5'-O-DMT-2'-O-propylphthalimidouridine can be modified with phosphoramidites to create novel modified nucleosides. The chemical name is 1-(5'-O-dimethoxytrityl)-2-[(2' -propyl)thio]uracil. This drug has CAS number 61381-14-4 and molecular weight of 271.11 g/mol.</p>Formula:C41H39N3O10Purity:Min. 95%Molecular weight:733.78 g/mol9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine
<p>9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine is a synthetic nucleoside that is activated by phosphorylation. It has been shown to be effective against cancer and viruses, and it has been proven to have a novel mechanism of action. 9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine is an analog of the natural product guanosine, which is found in RNA and DNA. 9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine can inhibit viral replication by inhibiting the synthesis of viral ribonucleic acid (RNA) and therefore inhibiting protein synthesis.</p>Purity:Min. 95%5-Fluorouridine
CAS:<p>5-Fluorouridine is an anticancer drug that belongs to the group of modified nucleosides. It is a synthetic nucleoside analogue that inhibits viral and DNA synthesis and can be used as antiviral agents. 5-Fluorouridine has also been shown to inhibit RNA synthesis in vitro. This compound is converted to uracil by deoxyribonucleotide reductase, which results in the formation of 5-fluoro-2'-deoxyuridine monophosphate (5FdUMP) and 5-fluoro-2'-deoxyuridine diphosphate (5FdUDP). The latter has been shown to inhibit DNA synthesis in vitro.</p>Formula:C9H11FN2O6Purity:Min. 95%Molecular weight:262.19 g/mol5-Ethynylpyrimidine
CAS:<p>5-Ethynylpyrimidine is a supramolecular alkynyl group that has been shown to inhibit tyrosine kinase activity, cross-coupling, and the synthesis of proteins. It also exhibits luminescent properties and can be used in supramolecular chemistry. 5-Ethynylpyrimidine is a pyrimidine nucleoside, which is an organic compound that is a component of RNA. Pyrimidine nucleosides are important for protein synthesis and are used as luminophores or fluorescent resonance quenchers in biochemical assays for enzyme activity; they have also been shown to inhibit herpes simplex virus (HSV) replication. 5-Ethynylpyrimidine has been found to be able to bind terminal alkynes with high affinity.</p>Formula:C6H4N2Purity:Min. 95%Molecular weight:104.11 g/molAICAR 3',5'-cyclic phosphate
CAS:<p>AICAR 3',5'-cyclic phosphate is an antiviral and anticancer agent that inhibits the production of DNA and RNA, which may be due to its ability to activate AMP-activated protein kinase. AICAR 3',5'-cyclic phosphate has been shown to inhibit the proliferation of human breast cancer cells in vitro. This drug also has anticancer activity against various types of cancers, including prostate cancer and melanoma. AICAR 3',5'-cyclic phosphate is a novel compound that can be used as a phosphoramidite reagent for the synthesis of oligonucleotides.</p>Formula:C9H13N4O7PPurity:Min. 95%Molecular weight:320.2 g/molCytidyl-3'-5'-adenosine ammonium salt
<p>Cytidyl-3'-5'-adenosine ammonium salt is a novel synthetic monophosphate nucleoside with antiviral and anticancer properties. It is synthesized from adenosine and cytidine, which are natural nucleosides. Cytidyl-3'-5'-adenosine ammonium salt is a high purity, high quality product that has been modified to target the ribonucleotide reductase enzyme. This enzyme controls the production of DNA in the cell, preventing it from reproducing. This product can be used as an activator for other chemotherapeutic drugs or as an anticancer drug itself.</p>Purity:Min. 95%2'-Methyl-guanosine-(iBu)-succinyl-CPG; 500 Å (RNA)
<p>2'-Methyl-guanosine-(iBu)-succinyl-CPG is a modified nucleoside with antiviral and anticancer properties. It is synthesized by the condensation of 2'-methyl-guanosine and succinic anhydride in the presence of tetrazole. The compound is a phosphoramidite, which is used as a building block for DNA synthesis.</p>Purity:Min. 95%4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate
<p>4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate is a synthetic nucleotide that can be activated to form an antiviral and anticancer agent. This compound has been shown to inhibit the proliferation of leukemia cells in culture. It also inhibits the synthesis of DNA and RNA, leading to cell death by inhibiting the production of proteins vital for cell division. 4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate is a novel nucleoside with high purity and CAS number: 57314-27-1.</p>Formula:C19H21N6O10PPurity:Min. 95%Molecular weight:524.38 g/mol5'-O-Acetyl-2',3'-O-isopropylideneadenosine
CAS:<p>5'-O-Acetyl-2',3'-O-isopropylideneadenosine is an anti-leishmanial agent that is synthesized from 2,3-O-isopropylideneadenosine by acetylating the 5' hydroxyl group. It was found to be more potent than the parent compound and other related compounds in inhibiting Leishmania amazonensis promastigotes. The proposed mechanism of action of 5'-O-acetyl-2',3'-O-isopropylideneadenosine involves hydrogen bonding with the guanosine moiety of DNA and inhibition of RNA synthesis. This drug also has an effect on carbonyl oxygens and resonances, which are observed in the nmr spectra. The synthetic scheme for this drug starts with uridine, which is converted to cytidine by reacting it with sodium cyanide in aqueous solution at 0°C. Cytidine</p>Formula:C15H19N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:349.34 g/mol2-Amino-benzoyl-9-(5'-O-DMT-b-D-ribofuranosyl)purine
<p>2-Amino-benzoyl-9-(5'-O-DMT-b-D-ribofuranosyl)purine is an anticancer and antiviral agent. It has been shown to be active against many viruses, including herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, and human immunodeficiency virus type 1. This compound also exhibits antitumor activity in mice and rats.</p>Formula:C38H35N5O7Purity:Min. 95%Molecular weight:673.71 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Q linker CPG 1000Å
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Q linker CPG 1000Å is a nucleoside analog that is used in the synthesis of DNA. It is a phosphoramidite that has been modified with an acetyl group at the 2' position and a Q linker at the 3' position. This product can be used as an antiviral or anticancer agent, as well as for other research purposes. The CAS number for this product is 62660-67-7, and it has been shown to be active against HIV and HCV.</p>Purity:Min. 95%5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-chlorouridine
CAS:<p>5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-chlorouridine is a novel antiviral agent that inhibits replication of viruses. It is synthesized from 5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine, which is then phosphorylated by the addition of a phosphate group. This compound has shown to be an activator in the synthesis of ribonucleosides and deoxyribonucleosides. The high purity and high quality of this compound make it suitable for use as a starting material for the synthesis of modified nucleosides for anticancer drugs.</p>Formula:C12H14ClIN2O5Purity:Min. 95%Molecular weight:428.61 g/mol2',3'-Dideoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:<p>2',3'-Dideoxycytidine-5'-triphosphate lithium salt is a novel nucleoside, which can be used in the synthesis of oligonucleotides and DNA. The phosphoramidite is highly reactive and stable, and has been shown to have antiviral activity against influenza A virus. This chemical has also been shown to inhibit the growth of cancer cells by inhibiting DNA synthesis.</p>Formula:C9H16N3O12P3Purity:Min. 95%Molecular weight:451.16 g/mol2',3'-Di-O-isopropylidene-isocytidine
CAS:<p>2',3'-Di-O-isopropylidene-isocytidine is a nucleoside that belongs to the group of antiviral and anticancer compounds. It is an analog of cytidine, and has been shown to be an activator of phosphoramidites, DNA, and RNA. 2',3'-Di-O-isopropylidene-isocytidine has been shown to have antineoplastic effects on tumor cells by inhibiting rna synthesis and protein synthesis. This compound also inhibits the growth of bacteria, including Mycobacterium tuberculosis and Mycobacterium avium complex. 2',3'-Di-O-isopropylidene-isocytidine has been shown to be a novel modified nucleoside with high purity and high quality.</p>Purity:Min. 95%2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine
CAS:<p>2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine is a modified nucleoside that is structurally similar to the natural nucleoside uridine. It has antiviral properties and can be used as a monophosphate, diphosphate, or nucleotide. 2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine is synthesized by reacting 5′-(triacetyl)aminoimidazole with 5′-(triisopropyl)phosphoroamidite in acetonitrile. The product has been shown to have anticancer activity in vitro and in vivo.</p>Purity:Min. 95%N2-O-Acetyl-2'-deoxy-3',5'-di-O-acetyl-O6-DPC-a-b-guanosine
<p>N2-O-Acetyl-2'-deoxy-3',5'-di-O-acetyl-O6-DPC-a-b-guanosine is a modified nucleoside that has antiviral and anticancer activities. It is synthesized by the modification of deoxyribonucleosides with acetyl groups at the 2' position, which are then removed using hydrolysis. The resulting product is a phosphoramidite intermediate that can be used in the synthesis of oligodeoxynucleotides. This compound has shown to have high quality and purity, as well as being novel.</p>Purity:Min. 95%
