Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3573 products of "Nucleosides"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
2'-Deoxy-5-(trifluoromethyl)cytidine
CAS:2'-Deoxy-5-(trifluoromethyl)cytidine is a synthetic nucleoside analogue that inhibits the cytidine deaminase enzyme. It is used in the treatment of some types of leukemia and other cancers. The compound, which has a trifluoromethyl group on the 2' position, binds to the active site of cytidine deaminase and prevents it from functioning. This leads to an accumulation of thymidylate, which is required for DNA synthesis. The tumor tissue also contains high concentrations of this drug and its metabolites, making it more effective against cancer cells than normal cells. 2'-Deoxy-5-(trifluoromethyl)cytidine has been shown to inhibit anabolism in tumor tissue in the presence of high concentrations of phosphorylases, which are enzymes that catalyze reactions that break down carbohydrates and proteins into smaller molecules such as glucose or amino acids.Formula:C10H12F3N3O4Purity:Min. 95%Molecular weight:295.22 g/mol3'-O-Propargylguanosine
3'-O-Propargylguanosine is a ribonucleoside that is structurally related to guanosine. It has antiviral and anticancer activities, but its most important function is as a substrate for the synthesis of DNA and RNA. The compound is used in the preparation of nucleosides and nucleotides, which are used in DNA synthesis. 3'-O-Propargylguanosine can be synthesized from diphosphate, phosphoramidites, or modified monophosphate. The CAS number for this product is 583-85-4.Formula:C13H15N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:321.29 g/mol5’-O-DMT-N2-isobutyryl-2’-O-propargylguanosine
CAS:5’-O-DMT-N2-isobutyryl-2’-O-propargylguanosine is an antiviral, anticancer, and nucleoside monophosphate. It is a novel and modified nucleoside. This product has high purity, high quality, and is also a phosphoramidite.Purity:Min. 95%Benzyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside
CAS:Benzyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside is a synthetic nucleoside analog. It is an antiviral agent that inhibits the activity of reverse transcriptase and DNA polymerase. Benzyl 2-acetamido-2-deoxy--3,4,6--tri--O--acetyl--β--D--glucopyranoside has been shown to be active against hepatitis B virus and herpes simplex virus type 1. It also has been shown to inhibit the production of HIV in cell culture and is being investigated as a potential anti AIDS drug.Purity:Min. 95%Chemical phosphorylating reagent (cpr)
CAS:Chemical phosphorylating reagent (CPR) is a powerful tool for the study of kinases, which are enzymes that regulate cellular processes such as cell division and apoptosis. CPR has been shown to be effective in inhibiting the activity of certain kinases that are involved in tumor growth and progression. It has also been used as an anticancer agent, inducing apoptosis in cancer cells. CPR is an analog of toxaphene and labetalol, two compounds with known kinase inhibitor activity. This reagent has been tested on human urine samples and Chinese hamster ovary cells, demonstrating its potential as a valuable research tool for studying kinase signaling pathways and developing new cancer therapies.Formula:C5H10O5Purity:Min. 95%Molecular weight:150.13 g/mol2'-Deoxyguanosine-5'-triphosphate sodium salt - 100mmol solution
CAS:2'-Deoxyguanosine-5'-triphosphate sodium salt is a triphosphate with antiviral and antifungal activity. It has been shown to inhibit the proliferation of HL60 cells and induce apoptosis in IL-2 receptor-bearing cells. The compound inhibits the growth of opportunistic fungi, such as Aspergillus niger and Candida albicans, by binding to deoxyguanosine residues in DNA. The compound also blocks polymerase activity, preventing DNA replication. 2'-Deoxyguanosine-5'-triphosphate sodium salt is used as a model system for studying the binding of nucleoside analogs to DNA. This drug is prepared as an injection solution for intravenous administration.
Formula:C10H16N5O13P3Purity:Min. 95%Molecular weight:507.18 g/molMethyl 2,4-dimethoxypyrimidine-5-carboxylate
CAS:Methyl 2,4-dimethoxypyrimidine-5-carboxylate is a novel anticancer drug that inhibits the growth of cancer cells by blocking DNA polymerase. It is a monophosphate nucleoside analogue that is phosphorylated to methyl 2,4-dimethoxypyrimidine-5′-diphosphate. This compound has been shown to be more effective than other nucleosides in inhibiting the growth of human leukemia cells and it may have potential as a therapeutic agent for treatment of some forms of cancer.Purity:Min. 95%1-(2'-Deoxy-5'-O-DMT-3'-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine
CAS:1-(2'-Deoxy-5'-O-DMT-3'-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine is a synthetic nucleoside that is used as an activator of phosphoramidites. It has been shown to be active against cancer cells and viruses. 1-(2'-Deoxy-5'-O-DMT-3'-O-nitrophenylsulphonyl-b-D-lyxofuranosyl)thymine can be modified to produce other nucleosides, including deoxyribonucleosides, ribonucleosides, or monophosphate nucleotides. 1-(2'-Deoxy-5'-O-DMT-3'-O-nitrophenylsulphonyl -b -D -lyxofuranosyl)thymine has not yet been approved for use in humans.Formula:C37H35N3O11SPurity:Min. 95%Molecular weight:729.75 g/molN4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine
N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine is an antiviral drug that inhibits viral DNA synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. It is a nucleoside analog that is used for the treatment of cancer and for the prevention of AIDS. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5 -iodocytidine is synthesized in high purity, with a purity level of > 98%. This product can be used as an activator or ligand in phosphoramidite synthesis.Formula:C22H30IN3O5SiPurity:Min. 95%Color and Shape:PowderMolecular weight:571.48 g/molCytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide
CAS:Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is a novel cytidine phosphoramidate monophosphate that has been shown to have anticancer and antiviral properties. It can be used as a DNA nucleoside phosphoramidite in the synthesis of oligonucleotides or as an antiviral agent by inhibiting viral RNA replication. Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is chemically synthesized in high purity and quality for use in research in the field of DNA, nucleosides, and antiviral agents.Formula:C30H52N7O9PPurity:Min. 95%Molecular weight:685.75 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-2'-fluoro-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a modified nucleoside that has been shown to inhibit the growth of cancer cells. It is synthesized by the reaction of 2'-deoxy-5'-O-dimethoxytriphenylmethyl adenosine 3'-chloroethylphosphoramidite and 2',6' -difluoroaniline in an organic solvent. The product is purified by silica gel column chromatography, followed by recrystallization from a mixture of methanol and water. This novel nucleoside may prove to be a useful anticancer agent as it inhibits the growth of cancer cells without producing any apparent toxicity for normal cells.Purity:Min. 95%2'-Deoxy-N2-isobutyryl-3'-O-levulinoylguanosine
CAS:2'-Deoxy-N2-isobutyryl-3'-O-levulinoylguanosine is a monophosphate antiviral agent that inhibits the synthesis of viral RNA by blocking the activity of DNA polymerase. It has been shown to be active against Herpes simplex virus type 1 and 2 (HSV1, HSV2) and cytomegalovirus (CMV). This compound also has anticancer activity due to its ability to inhibit cell proliferation and induce apoptosis in cancer cells. The antiviral activity of 2'-deoxy-N2-isobutyryl-3'-O-levulinoylguanosine is not limited to herpes viruses and also includes HIV, human T lymphotropic virus type I (HTLV1), and human cytomegalovirus. This product is synthesized with high purity, high quality, and high yield.
Formula:C19H25N5O6Purity:Min. 95%Molecular weight:419.44 g/molAdenosine 5'-(tetrahydrogen triphosphate)
CAS:Adenosine is a nucleoside consisting of adenine and ribose. It is used in biochemical analysis to quantify the cytosolic Ca2+ concentration, which is an important cellular signal that regulates many cellular processes. Adenosine stimulates the uptake of Ca2+ by binding to the monophosphate-activated protein (AMPAR), which results in the opening of voltage-gated calcium channels. These channels allow Ca2+ to enter the cell, increasing its intracellular concentration. Adenosine also has been shown to stimulate muscle contraction through increased release of Ca2+. This drug also possesses inhibitory effects on synaptic transmission and may have anti-inflammatory properties due to its ability to inhibit proteolytic enzymes in muscle cells.Formula:C10H14MgN5O13P3Purity:Min. 95%Molecular weight:529.47 g/molU-13C10, U-[15N2]-mono-Labelled Thymidylyl-3'-5'-thymidine ammonium (compound A)
U-13C10, U-[15N2]-mono-Labelled Thymidylyl-3'-5'-thymidine ammonium (compound A) is a novel anticancer drug that is synthesized by phosphoramidite chemistry. It is an activator of DNA synthesis and has been shown to be cytotoxic against cancer cells in vitro. This compound is also a high quality nucleoside analogue. The molecular weight of this compound is 434.4 g/mol and it has a CAS number of 81633-09-9.Formula:C20H30N5O12PPurity:Min. 95%Molecular weight:563.45 g/mol5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine
CAS:5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine is an activator that can be used to treat cancer. It is synthesized from the natural amino acid inosine by replacing the amine group with ethyl carboxamide. The synthesis of this molecule is currently in progress. This product has shown anticancer activity and antiviral effects, as well as high purity and novel properties.Formula:C15H20N6O4Purity:Min. 95%Molecular weight:348.36 g/molKinetin riboside-5'-diphosphate sodium salt
Kinetin riboside-5'-diphosphate sodium salt is a synthetically modified nucleoside that is used as an activator for DNA synthesis and in the treatment of cancer. Kinetin riboside-5'-diphosphate sodium salt has been shown to have antiviral and anticancer effects, as well as being able to modify the activity of natural substances such as kinetin. This compound has been shown to inhibit tumor growth and reduce the size of some types of tumors in mice. It also inhibits viral replication by blocking viral RNA polymerase activity and inhibiting viral protein synthesis.Purity:Min. 95%Biotin-11-2-deoxyuridine-5-triphosphate tetralithium salt
CAS:Biotin-11-2-deoxyuridine-5-triphosphate tetralithium salt is a modified nucleoside that is used in antiviral and anticancer treatments. The deoxyribonucleosides are synthesized by coupling biotin to 2'-deoxyuridine 5'-triphosphate, which is then reacted with lithium tetralithium chloride. This product has been shown to be an activator of DNA synthesis and can induce the proliferation of cancer cells. Biotin-11-2-deoxyuridine-5-triphosphate tetralithium salt has been shown to inhibit the growth of both human immunodeficiency virus (HIV) and murine leukemia virus (MLV). Biotin-11-2-deoxyuridine-5-triphosphate tetralithium salt is also used in the synthesis of ribonucleosides for use in DNA research. ItFormula:C24H41N6O17P3S·4LiPurity:Min. 95%Molecular weight:886.41 g/molThymidine 5'- triphosphate lithium salt - 100mM aqueous solution
CAS:Thymidine 5’-triphosphate tetralithium salt (dTTP) is a crucial component in chemical biology research. It is a modified form of thymidine, containing three phosphate groups. Important in DNA replication and repair, dTTP acts as a substrate for DNA polymerases during polymerase chain reactions (PCR), facilitating the amplification of specific DNA sequences. In addition, in DNA sequencing, dTTP is incorporated into newly synthesized DNA strands, allowing precise determination of nucleotide sequences.Formula:C10H17N2O14P3·xLiPurity:Min. 95%Molecular weight:482.17 g/mol6-Bromo-4-chloropyrido[2,3-d]pyrimidine
CAS:6-Bromo-4-chloropyrido[2,3-d]pyrimidine is a pyrimidine derivative that has been synthesized using cyclization and condensation techniques. The synthesis of this compound is efficient and uses relatively low amounts of starting materials. It can be made using microwave irradiation in a high yield. 6-Bromo-4-chloropyrido[2,3-d]pyrimidine is an aromatic ring with efficient methods for synthesis and bromination. This research could be used to produce new compounds with similar structures that are more potent than current drugs.Purity:Min. 95%5'-Azido-N6-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
CAS:5'-Azido-N6-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is an antiviral and anticancer agent that inhibits the replication of RNA and DNA. It inhibits viral infection by inhibiting the synthesis of viral genomes, which are made up of DNA or RNA. 5'-Azido-N6-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel modified nucleoside analog that blocks the incorporation of ribonucleotides into viral DNA or RNA. The drug has been shown to be effective against Hepatitis B, Hepatitis C, HIV, and other viruses. This compound can also be used as a chemotherapeutic agent for cancer treatment due to its inhibition of DNA synthesis.Formula:C18H24N8O5Purity:Min. 95%Molecular weight:432.43 g/mol
![U-13C10, U-[15N2]-mono-Labelled Thymidylyl-3'-5'-thymidine ammonium (compound A)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FTM32169.webp&w=3840&q=75)
![6-Bromo-4-chloropyrido[2,3-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNB44335.webp&w=3840&q=75)
