Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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N4-Acetyl-2'-deoxy-5'-O-tritylcytidine
CAS:N4-Acetyl-2'-deoxy-5'-O-tritylcytidine is a novel nucleoside that is synthesized by modifying cytidine to form an acetylated nucleotide. It has been found to be an effective inhibitor of DNA synthesis and antiviral agent.Formula:C30H29N3O5Purity:Min. 95%Molecular weight:511.57 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.Purity:Min. 95%2'-O-Acetyl-3'-deoxy-3-deaza-3'-fluoro-5'-O-toluoyluridine
CAS:2'-O-Acetyl-3'-deoxy-3-deaza-3'-fluoro-5'-O-toluoyluridine is an antiviral agent that has been shown to be active against a number of viruses, including HIV. It is a novel nucleoside analog that has been modified with the addition of acetyl and toluoyl moieties at the 2' position. The compound exhibits high antiviral potency in vitro and in vivo, and has an excellent safety profile. This novel anticancer agent also inhibits DNA synthesis by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase activity.Purity:Min. 95%2',3',5'-Tri-O-acetylguanosine
CAS:2',3',5'-Tri-O-acetylguanosine is a protected form of the nucleoside guanosine which has potential application as a synthetic intermediate in nucleic acid and nucleoside chemistry.Formula:C16H19N5O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:409.35 g/mol5’(R)-C-Methyl-5-methyluridine
CAS:5’(R)-C-Methyl-5-methyluridine is an nucleoside and a ribonucleoside. It has antiviral, anticancer, and DNA modifying properties. This product is used in research to make phosphoramidites, diphosphates, and deoxyribonucleosides. 5’(R)-C-Methyl-5-methyluridine is also used in the production of modified oligonucleotides as well as other novel DNA compounds.
Purity:Min. 95%8-Hydrazinoadenosine
CAS:8-Hydrazinoadenosine is an inhibitor of phosphodiesterase, which is a key enzyme in the regulation of cellular processes. 8-Hydrazinoadenosine binds to the active site of the enzyme and inhibits its function. This binding prevents hydrolysis of the phosphate bond between two nucleotides and so prevents the formation of a new nucleotide from a nucleoside and a phosphate molecule. 8-Hydrazinoadenosine has been shown to inhibit phosphodiesterases in vitro and in animals, including rat brain and mouse lung. Strategies for 8-hydrazinoadenosine commercialization have been investigated, including attaching it to other molecules that are more easily absorbed by cells or using irradiation to produce 8-aminoadenosine, which can be converted into 8-hydrazinoadenosine.Purity:Min. 95%5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite
5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a nucleoside which is an activator for DNA synthesis. It is synthesized from the natural substance thymidine, and it can be modified to have various properties by changing the chemical group that attaches to the 3' carbon. 5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a novel nucleoside that has been shown to be anticancerous in vitro. This compound may also play a role in treating viral infections due to its antiviral properties.Formula:C25H45N4O6PSiPurity:Min. 95%Molecular weight:556.72 g/molDenufosol tetrasodium
CAS:A P2Y2 receptor agonist that has been studied in cystic fibrosis and retinal diseases such as retinal detachment. Denufosol was studied as an inhaled drug for cystic fibrosis, due to its ability to activate an alternative chloride channel and avoiding the defective CFTR chloride channel. This enhances hydration of the lung mucosa and improves mucociliary clearance. The drug did not progress from phase III clinical trials. Denufosol resulted in subretinal fluid reabsorption in in vivo model of retinal detachment.
Formula:C18H23N5Na4O21P4Purity:Min. 90 Area-%Color and Shape:PowderMolecular weight:861.25 g/molN6,7-Dimethyldeoxyadenosine
N6,7-Dimethyldeoxyadenosine is a nucleoside with antiviral and anticancer properties. It is a modified DNA monophosphate with the chemical formula C8H16N2O6P. N6,7-dimethyldeoxyadenosine has been shown to inhibit the replication of HIV and herpes simplex virus type 1 (HSV-1) in vitro. This compound also inhibits the growth of cancer cells in culture and has been suggested as an anticancer therapeutic agent.Purity:Min. 95%N4-Acetylcytidine
CAS:N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.Formula:C11H15N3O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:285.25 g/molS-Adenosyl-L-methionine p-toluenesulfonate
CAS:Methyl donor and a cofactor for enzyme-catalyzed methylationsFormula:C15H23N6O5S•C7H7O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:570.64 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine
CAS:This is a nucleoside analog that has antiviral properties. It is a monophosphate derivative of 2'-deoxy-5'-O-DMT-2'-fluoro-5-methyluridine and has been shown to be an activator of RNA polymerase II transcription in vitro. This compound is also a novel, high quality, high purity reagent for the synthesis of phosphoramidites. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is CAS No. 133324-02-4 and can be used as a diphosphate or DNA nucleoside analog with antiviral properties. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is synthesized by reacting 5' deoxyribose phosphate with the corresponding 2',3' or 4' fluoro amidite in the presence of a base. The ribonucleFormula:C31H31FN2O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:562.59 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.Formula:C38H37N3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:663.72 g/mol6-O-Methyl-2'-deoxyinosine
CAS:6-O-Methyl-2'-deoxyinosine is a modified nucleoside that inhibits the synthesis of DNA and RNA. It is also an anticancer agent, inhibiting the growth of tumor cells by arresting the cell cycle at the G1 phase. 6-O-Methyl-2'-deoxyinosine is a phosphoramidite for use in solid phase synthesis of oligodeoxynucleotides (ODN). This product has high purity, good quality, novel structures and excellent stability.
6-O-Methyl-2'-deoxyinosine can be used to inhibit viral replication by preventing viral DNA from being replicated into double stranded DNA. The antiviral activity of 6-O-methyl 2'-deoxyinosine against HIV has been demonstrated in vitro and in vivo using monophosphate forms.Purity:Min. 95%Polyinosinic acid-polycytidylic acid, homopolymer (1:1)
CAS:Polyinosinic acid-polycytidylic acid (Poly I:C), an agonist of TLR3 toll-like receptors, is a synthetic double-stranded RNA analog, consisting of polyinosinic acid (poly I) paired with polycytidylic acid (poly C), forming a stable duplex structure.PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes.We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products. For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'Formula:(C10H13N4O8P)x•(C9H14N3O8P)xColor and Shape:Powder2'-C-Methylcytidine
CAS:Broad-spectrum anti-viral; inhibitor of HCV NS5B RNA polymeraseFormula:C10H15N3O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:257.25 g/molN4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite is an activator and antiviral agent that inhibits viral DNA synthesis by terminating the elongation step of viral DNA chain extension. N4-Acetyl-5'-O-DMT-2'-O-propynylcytidine 3'-CE phosphoramidite has a novel structure and is synthesized by modified chemical reactions. It can be used in the synthesis of oligonucleotides or as a building block for the synthesis of other nucleosides.Formula:C44H52N5O9PPurity:Min. 95%Molecular weight:825.89 g/mol5-Methyl-2-thiouridine
CAS:5-Methyl-2-thiouridine is a nucleotide that is found in the type strain of Escherichia coli. It has been shown to be an effective inhibitor of protein synthesis, with optimum concentration at 0.1 mM. 5-Methyl-2-thiouridine binds to the ribosome and inhibits its activity. 5-Methyl-2-thiouridine also interacts with human mitochondrial RNA and alters its structure, leading to an antibody response that protects against infection by the bacteria in question. This nucleotide has also been shown to inhibit bacterial growth in wastewater treatment plants. The chemical structures of 5-methyluridine are similar to those of uridine except for a methyl group on the second carbon atom (5 position). The presence of this methyl group confers increased water permeability and decreased kinetic energy on the molecule, which can be detected using nuclear magnetic resonance spectroscopy.
Formula:C10H14N2O5SPurity:Min. 95%Color and Shape:White PowderMolecular weight:274.29 g/mol6-Azacytidine
CAS:6-Azacytidine is a molecule that contains a hydroxyl group and a glycosidic bond. It has been shown to inhibit the growth of mollicutes, which are non-cellular bacteria. 6-Azacytidine has also been shown to be toxic in animal tissue culture studies. The drug can be eliminated through the urine or bile after being metabolized by the liver. 6-Azacytidine is not active against human cells in cell culture, but it does show some toxicity against human liver cells.Formula:C8H12N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:244.2 g/mol1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine
CAS:1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine is a cytosine analog that is structurally similar to the antiviral drug tenofovir. It has been shown to be active against human serum and logarithmic growth phase cells, as well as cancer cell lines. 1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine inhibits HIV infection in vitro by binding to the viral reverse transcriptase enzyme, blocking its activity and preventing DNA synthesis. This drug also inhibits the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in cell culture.Formula:C9H12FN3O3Purity:Min. 95%Molecular weight:229.21 g/mol
