
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3567 products of "Nucleosides"
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3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine
Controlled Product<p>3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine is a novel modified nucleoside that has antiviral and anticancer properties. It is an activator of the DNA polymerase, ribonucleotide reductase, and thymidine kinase enzymes. 3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine has been shown to inhibit the growth of human cancer cells in vitro and in vivo.</p>Formula:C18H18N3O7D3Purity:Min. 95%Molecular weight:394.39 g/mol5'-O-Methoxytrityluridine 3'-CE phosphoramidite
<p>5'-O-Methoxytrityluridine 3'-CE phosphoramidite is a modified nucleoside that can be used in the synthesis of DNA and RNA. It is an activator that activates ribonucleotides to diphosphates. 5'-O-Methoxytrityluridine 3'-CE phosphoramidite has been shown to have antiviral, anticancer, and novel activities. This product is CAS No. 57747-00-2, High purity, deoxyribonucleosides, and high quality.</p>Formula:C39H47N4O8PPurity:Min. 95%Molecular weight:730.81 g/mol2'-Deoxy-2',2'-difluoro-a-uridine
CAS:<p>2'-Deoxy-2',2'-difluoro-a-uridine is a nucleoside analog with modifications on the 2'-carbon of the ribose sugar and the pyrimidine base uracil. This compound is a synthetic derivative of uridine with two fluorine atoms attached to the 2' carbon of the sugar. The α-stereochemistry of the sugar indicates a specific configuration that influences how the molecule behaves in biological systems, including its interaction with enzymes and incorporation into nucleic acids.</p>Formula:C9H10F2N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:264.18 g/mol6-Thioguanosine-5'-O-triphosphate sodium - 10mM aqueous solution
CAS:<p>6-Thioguanosine-5'-O-triphosphate sodium salt is a nucleotide analog that inhibits the synthesis of RNA, DNA and protein. It binds to the guanine nucleotide-binding site on the enzyme RNA polymerase and blocks transcription. This leads to a decreased amount of mRNA, thereby slowing or stopping protein production. 6TGTP also has been shown to be effective in treating cancer as it inhibits enzymes involved in cellular metabolism and induces cell death. 6TGTP has been shown to have no effect on mammalian cells when incubated with 10 mM magnesium ion.</p>Formula:C10H16N5O13P3S•NaxPurity:Min. 95%Color and Shape:PowderMolecular weight:539.25 g/mol5'-(Furan-2-yl)-2’-O-methyluridine
CAS:<p>5'-(Furan-2-yl)-2’-O-methyluridine is a modified nucleoside that is used as an antiviral agent. It is a monophosphate nucleotide analog and has been shown to be active against HIV, herpes simplex virus, cytomegalovirus, and Epstein Barr virus. 5'-(Furan-2-yl)-2’-O-methyluridine is synthesized by the phosphoramidite method and has high purity and quality. The CAS number for this compound is 2095417-32-4.</p>Purity:Min. 95%5’-O-DMT-N1-methylpseudouridine
CAS:<p>5’-O-DMT-N1-methylpseudouridine is a monophosphate nucleoside that can be used for antiviral and anticancer purposes. This nucleoside has been shown to inhibit the synthesis of DNA and RNA, which may lead to apoptosis in cells infected by viruses. In addition, it has been shown to inhibit the proliferation of cancer cells by inhibiting protein synthesis. 5’-O-DMT-N1-methylpseudouridine is a novel nucleoside that is synthetically derived from uracil. The chemical structure of this product is different from other nucleosides because it contains a methyl group on the 5' hydroxyl group and an N1 methyl group on the 1'-hydroxyl group. This product is available in high purity and high quality.</p>Purity:Min. 95%5'-O-DMT-thymidine
CAS:<p>5’-O-DMT-thymidine is also known as 5’-O-(4,4’-dimethoxytrityl)thymidine. It is a key deoxynucleoside building block that is protected with a dimethoxytrityl group in the 5-O-position of the deoxy-ribose moiety, leaving the 3-hydroxyl free for modification. It is used a convenient starting point for nucleotide synthesis. 5’-O-DMT-thymidine can be converted into 3’-O-phosphoramidite derivatives for oligonucleotide synthesis. Additionally, 5’-O-DMT-thymidine can be converted into more stable 1-N-protected derivatives.</p>Formula:C31H32N2O7Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:544.6 g/mol3'-Amino-2',3'-dideoxyinosine
CAS:<p>3'-Amino-2',3'-dideoxyinosine acts as a chain terminator in DNA synthesis due to the absence of a 3'-hydroxyl group. The 3'-amino group allows for the attachment of various molecules to the 3' end of oligonucleotides, and the inosine base introduces the potential for wobble base pairing, making it a specialized tool for research and potential diagnostic applications.</p>Formula:C10H13N5O3Purity:Min. 95%Molecular weight:251.24 g/mol5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine
CAS:<p>5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine is a high purity phosphoramidite, deoxyribonucleoside, and ribonucleoside that can be used in the synthesis of antiviral drugs, anti-cancer agents, and nucleotides. 5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine has been shown to inhibit the growth of various cancer cells. This product also belongs to a novel class of synthetic nucleosides that can be modified with fluorine or other substituents at any position on the sugar ring.</p>Purity:Min. 95%4’-C-Methyl-4-deoxyuridine
CAS:<p>4’-C-Methyl-4-deoxyuridine is an antiviral and anticancer drug that belongs to the group of nucleosides. It has shown novel anti-tumor activities in vitro and in vivo, as well as antiviral effects against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). 4’-C-Methyl-4-deoxyuridine is a modified nucleoside that is synthesized from uridine. It has been shown to inhibit viral replication by inhibiting viral DNA synthesis. This drug also inhibits the multiplication of tumor cells by inhibiting DNA synthesis. The product is high purity, high quality, and CAS No. 1064364-21-1.</p>Purity:Min. 95%3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine
<p>3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine is a nucleoside that can be used as an antiviral and anticancer agent. It is structurally similar to thymidine, but differs by the replacement of a hydrogen atom at position 3 with a fluorine atom. The replacement of this hydrogen atom with a fluorine atom results in the removal of hydroxyl group from the 5' carbon position on the sugar ring, which is then converted into an ester moiety. 3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine has been shown to inhibit DNA replication, RNA transcription and protein synthesis. This nucleoside also has been found to stimulate apoptosis in cancer cells by inhibiting DNA replication.</p>Formula:C18H19FN2O5Purity:Min. 95%Molecular weight:348.43 g/mol3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole
CAS:<p>3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a nucleoside analog that is an antiviral and anticancer agent. It is a monophosphate, which has been shown to inhibit the replication of DNA by binding to the enzyme DNA polymerase. 3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole also inhibits protein synthesis and cell division by preventing the production of proteins vital for cell division. This drug has shown high purity and quality, as well as novel properties.</p>Formula:C41H36N2O5Purity:Min. 95%Molecular weight:636.74 g/mol2',3',5'-Tri-O-acetyluridine
CAS:<p>2',3',5'-Tri-O-acetyluridine is a uridine derivative with potential for use in organic synthesis such as the preparation of modified nucleosides, nucleotides, and RNA analogs.</p>Formula:C15H18N2O9Purity:Min. 95%Color and Shape:White PowderMolecular weight:370.31 g/molN2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine
<p>N2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine is a monophosphate analog of guanine. It is a novel antiviral agent that inhibits the DNA polymerase and RNA polymerase activities of human immunodeficiency virus (HIV). The drug has a high purity and is available in large quantities.</p>Formula:C14H19N5O6Purity:Min. 95%Color and Shape:PowderMolecular weight:353.33 g/mol2-Fluoroadenosine 5'-triphosphate sodium
CAS:<p>2-Fluoroadenosine 5'-triphosphate sodium salt is an analog of adenosine 5'-triphosphate (ATP) that has been used as a target molecule in binding experiments to identify cells that express the ATP receptor. 2-Fluoroadenosine 5'-triphosphate sodium salt binds to the surface glycoprotein on target cells and is internalized by endocytosis, resulting in cell death. This drug has also been shown to be effective against cancer cells grown in culture.</p>Formula:C10H15FN5O13P3•Na3Purity:Min. 95%Color and Shape:PowderMolecular weight:594.12 g/mol5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine
<p>5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine is a novel, synthetic nucleoside. It is a phosphoramidate prodrug of 5'-deoxy-5'-O-dimethoxytrityl-N4-isobutyrylcytidine, which is an antiviral and anticancer agent. 5'-O-DMT-N4-isobutyrylcytidine inhibits DNA synthesis by competitively inhibiting the activity of the enzyme ribonucleotide reductase (RNR).</p>Formula:C35H39N3O8Purity:Min. 95%Molecular weight:629.7 g/mol5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite
<p>5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer drug that inhibits viral and tumor DNA synthesis. It is a nucleoside monophosphate with antiviral and antitumor activities. The compound is synthesized by coupling a benzoyl group to 5'-O-DMT-2'-deoxyuridine 3'-phosphate, followed by the addition of a triethylammonium salt group. The phosphoramidite is then reacted with 2,4,6-trichlorophenylisocyanate to produce the final product. This product has a CAS number of 86825-34-1.</p>Formula:C25H33N4O7PPurity:Min. 95%Molecular weight:532.54 g/mol7-Methyl-2'-deoxywyosine
<p>7-Methyl-2'-deoxywyosine is a nucleoside analogue that inhibits the growth of cells by interfering with DNA replication. It is a modified form of deoxywyosine, which is the natural precursor of DNA and RNA. 7-Methyl-2'-deoxywyosine has antiviral activity against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (CMV). This compound has shown anticancer activity in vivo and in vitro, as well as high purity and quality.</p>Purity:Min. 95%N6-Methyl-2'-O-methyladenosine
CAS:<p>N6-Methyl-2'-O-methyladenosine is a nucleoside that is found in DNA. In some cases, the methyl group in this molecule can be modified, which can change its biological activity. N6-Methyl-2'-O-methyladenosine has been shown to reduce the severity of bowel disease and myocardial infarcts in experimental models. The structural analysis of vessels from patients with atherosclerosis revealed that this molecule inhibits vascular calcification. It also decreases expression of MMP-9, a protein involved in nephropathy and diabetic kidney disease. N6-Methyl-2'-O-methyladenosine is able to inhibit the development of vascular injury by blocking the activation of cells and reducing inflammation through pharmacological agents that are used in experimental models for blood vessel injury.</p>Formula:C12H17N5O4Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:295.29 g/mol3'-Amino-5'-O-p-anisoyl-2',3'-dideoxyuridine
<p>3'-Amino-5'-O-p-anisoyl-2',3'-dideoxyuridine is a novel compound that has been synthesized. This compound is a diphosphate, which can be used as an activator for the synthesis of modified nucleosides and antiviral agents. It is also a DNA phosphoramidite, which can be used in the synthesis of oligonucleotides with high purity and high quality.</p>Formula:C17H19N3O6Purity:Min. 95%Molecular weight:361.35 g/mol5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite
<p>5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite is an activator of DNA synthesis. It has antiviral and anticancer properties, which have been shown in animal models. This compound is a novel nucleoside phosphoramidite that can be used to synthesize oligonucleotides. The CAS number for this product is 98469-45-7.</p>Formula:C26H35N6O5PPurity:Min. 95%Molecular weight:542.58 g/mol6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine
CAS:<p>6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine is a synthetic nucleoside with antiviral and anticancer activity. It is an activator of the DNA polymerase, which is involved in the synthesis of DNA. The high purity of this product makes it a good choice for use in research or as a starting material for further chemical modification. 6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine has been shown to inhibit the growth of cancer cells, including breast, lung and colon carcinoma cells.</p>Formula:C26H23ClN4O5Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:506.95 g/mol2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine
CAS:<p>2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine is a synthetic, modified nucleoside. It is an activator of DNA synthesis, and it has been found to inhibit the growth of cancer cells in vitro. This compound has shown success in the treatment of HIV infection in vitro and has also been shown to be effective against hepatitis B virus (HBV) and herpes simplex virus type 1 (HSV). The compound may be useful as an antiviral agent.</p>Formula:C34H35N5O6Purity:Min. 95%Molecular weight:609.69 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite is an anticancer agent that acts by inhibiting the formation of DNA and RNA. It is a nucleoside analogue that has been modified to contain a benzoyl group at the 2' carbon atom, which leads to increased cytotoxicity. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite is a synthetic nucleoside analogue with novel properties. It inhibits the synthesis of DNA and RNA in cells, which may be due to its ability to inhibit DNA polymerases and ribonucleases.</p>Formula:C39H54N5O8PSiPurity:Min. 95%Molecular weight:779.95 g/molBucladesine calcium salt
CAS:<p>Protein kinase A inhibitor; cAMP agonist</p>Formula:C18H24N5O8PCaPurity:Min. 95%Color and Shape:PowderMolecular weight:489.42 g/mol3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine
<p>3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monoph</p>Formula:C38H34N8O5Purity:Min. 95%Molecular weight:682.73 g/mol6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine
<p>6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is an antiviral agent and anticancer drug. It inhibits viral replication by inhibiting the activity of DNA polymerase. 6-[Amino(2'-deoxyribofuranosyl)]-1-(2'-deoxyribofuranosyl)-4-methoxypyrazolo[3,4-d]pyrimidine has been shown to inhibit the growth of cancer cells without affecting healthy cells.</p>Purity:Min. 95%5'-Amino-2',5'-dideoxy-2'-fluorouridine
<p>5'-Amino-2',5'-dideoxy-2'-fluorouridine is an antiviral drug that is synthesized from the natural compound 5'-deoxy-5'-amino-2',5'-dideoxyuridine. The modified deoxyribonucleosides are activated by phosphorylation and can be incorporated into DNA by DNA polymerase, which prevents viral replication. The monophosphate form of this compound is used in cancer chemotherapy to inhibit the synthesis of RNA and proteins necessary for cell division. 5'-Amino-2',5'-dideoxy-2'-fluorouridine has been shown to be a potent anticancer agent, with activity against a variety of human tumor cell lines.</p>Purity:Min. 95%6-O-Methylinosine
CAS:<p>6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.</p>Formula:C11H14N4O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:282.25 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine
<p>N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine is a nucleoside that is chemically modified by the addition of a benzoyl group. It has antiviral, anticancer and antiretroviral activities. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine inhibits viral DNA synthesis by inhibiting both viral DNA polymerase and reverse transcriptase, which are enzymes required for the production of viral DNA. It also inhibits cancer cell growth by forming covalent bonds with deoxyribonucleic acid (DNA) in the cancer cells and initiating apoptosis. This nucleoside has been shown to be active against HIV, Herpes Simplex Virus Type 1 (HSV1), and Human Cytomegalov</p>Purity:Min. 95%2',3'-Dideoxy-5'-O-DMT-cytidine
CAS:<p>2',3'-Dideoxy-5'-O-DMT-cytidine is a chemically modified cytidine nucleoside which can be used in synthetic chemistry, especially in nucleic acid synthesis. A dimethoxytrityl (DMT) protecting group is attached to the 5'-oxygen of the sugar. This is not biologically active, but it’s commonly used in solid-phase oligonucleotide synthesis to protect the 5' end during step-by-step DNA or RNA construction.</p>Formula:C30H31N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:513.6 g/molDMT-2'-OMe-pseudouridine phosphoramidite
<p>DMT-2'-OMe-pseudouridine phosphoramidite is an antiviral, anticancer, and DNA synthesis inhibitor. It has been used in the synthesis of oligonucleotide probes for sequencing and hybridization studies. DMT-2'-OMe-pseudouridine phosphoramidite is a modified nucleoside that is used as a building block for the synthesis of DNA. This compound is synthesized from 2'-deoxy-5-methyluridine and dimethoxytrityl chloride. DMT-2'-OMe-pseudouridine phosphoramidite inhibits the synthesis of RNA and DNA by binding to ribonucleotides and deoxyribonucleotides during the polymerization reaction, thereby blocking the progression of the reaction.</p>Purity:Min. 95%8-Aza-6-hydroxy-2-mercaptopurine
CAS:<p>8-Aza-6-hydroxy-2-mercaptopurine (8AzaMP) is a novel nucleoside analog that is an activator of the thymidylate synthase enzyme. It has been shown to inhibit the replication of many DNA viruses and to inhibit tumor growth in animal models. 8AZA MP has been evaluated in Phase I and II clinical trials for the treatment of various cancers, including malignant melanoma, renal cell carcinoma, and chronic lymphocytic leukemia. This drug has also shown promise as a chemotherapeutic agent for AIDS patients with HIV infection or AIDS-related complex.</p>Formula:C4H3N5OSPurity:Min. 95%Color and Shape:PowderMolecular weight:169.17 g/mol1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)-5-methyluracil
<p>1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)-5-methyluracil is an anticancer and antiviral nucleoside. It has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1). This compound inhibits viral DNA synthesis by competing with the natural substrate for HIV reverse transcriptase, 3'-deoxyadenosine 5'-triphosphate. It also prevents the in vitro proliferation of lymphocytes, which may be due to its inhibition of DNA synthesis. 1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)-5-methyluracil is also an activator of phosphoramidites, which are used in the production of oligonucleotides and other modified nucleosides.</p>Purity:Min. 95%Cytidine 5'-monophosphate free acid
CAS:<p>Cytidine 5'-monophosphate is a nucleotide that is important in the synthesis of DNA and RNA. It is a precursor to uridine monophosphate (UMP) and uridylic acid (UDP). Cytidine 5'-monophosphate has been found to inhibit the growth of antibiotic-resistant strains of bacteria, such as those resistant to ampicillin, chloramphenicol, tetracycline, kanamycin, and streptomycin. Cytidine 5'-monophosphate also has inhibitory properties against energy metabolism and protein oxidation in bowel disease. This nucleotide has been shown to increase the rate constant for polymerase chain reaction (PCR) by up to 10-fold.</p>Formula:C9H14N3O8PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:323.2 g/molN6-Acetyladenosine
CAS:<p>N6-Acetyladenosine is a nucleoside that belongs to the group of N-acetylated adenosines. It is found in thermophilic organisms and has been shown to be involved in optimal growth. N6-Acetyladenosine has also been found to be an important part of the coding and population modifications of crenarchaeota, archaeal organisms that are phylogenetically related to methanogens. Unfractionated populations of methanogen contain both N6-acetyladenosine residues and other modified adenosines, with each organism differing in the types of modifications they contain. Transfer of these modified adenosines from one organism to another can lead to changes in their coding and population modifications.</p>Formula:C12H15N5O5Purity:Area-% Min. 90 Area-%Color and Shape:White PowderMolecular weight:309.28 g/mol2',3'-Dideoxy-2',3'-didehydroadenosine
CAS:<p>2′,3′-Dideoxy-2′,3′-didehydroadenosine, abbreviated to d4A, is a synthetic purine nucleoside analog. Possible applications are its use to study antiviral activity.</p>Formula:C10H11N5O2Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:233.23 g/mol3'-Azido-3'-deoxy-b-L-cytidine
CAS:<p>3'-Azido-3'-deoxy-b-L-cytidine is a novel nucleoside that has been shown to be an activator of the ribonuclease activity of purified RNase A in vitro. This product is suitable for use in synthesis of oligodeoxynucleotides and phosphoramidites. 3'-Azido-3'-deoxy-b-L-cytidine can be used as a potential anticancer drug or antiviral agent.</p>Purity:Min. 95%5'-Amino-5'-deoxy-2'-O-methyluridine
<p>5'-Amino-5'-deoxy-2'-O-methyluridine is a novel nucleoside analog with antiviral and anticancer properties. 5'-Amino-5'-deoxy-2'-O-methyluridine is an activator of the immune system, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase. This drug has shown activity against a variety of human tumor cell lines in vitro and in vivo. 5'-Amino-5'-deoxy-2'-O-methyluridine also inhibits the growth of several bacterial strains, including methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium avium complex.</p>Purity:Min. 95%N2,2'-O-Dimethylguanosine
CAS:<p>N2,2'-O-Dimethylguanosine is a nucleoside that belongs to the category of modified bases. It is synthesized from adenosine and a methyl group by a mutant strain of Escherichia coli. N2,2'-O-Dimethylguanosine can be identified by its characteristic UV-visible spectrum and high retention time on chromatographic columns. It has been shown to inhibit translation in E. coli at concentrations as low as 1 mM and also inhibits growth rate at concentrations as low as 2 mM. The chemical structure of this compound is similar to that of guanosine, but it contains an extra methyl group on its 2' carbon atom. This chemical modification may result in changes in the way the molecule interacts with other molecules or how it functions in the cell. <br>N2,2'-O-Dimethylguanosine was first identified from a mutant strain of Escherichia coli that had been subjected to mutagenesis</p>Formula:C12H17N5O5Purity:Min. 95%Molecular weight:311.29 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is a nucleotide that is used in the synthesis of DNA. It is an organic compound consisting of a molecule with a phosphate group at one end and a ribose sugar at the other. 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is synthesized on a solid support by reacting nucleophilic reagents with the ribonucleoside. This drug has antineoplastic effects, inhibiting cancer cell growth by interfering with the production of ribonucleic acid (RNA) and protein synthesis. Hydrolysis of this drug releases fluorouracil, which inhibits thymidylate synthase, preventing the conversion of dUMP to dTMP, and thus blocking DNA synthesis.</p>Formula:C39H46FN4O8PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:748.78 g/molN6,N6,2'-O-Trimethyladenosine
CAS:<p>N6,N6,2'-O-Trimethyladenosine is a nucleoside that is found in small quantities in human tissues. It is synthesized by the enzyme polymerase from adenosine and S-adenosyl-L-methionine. N6,N6,2'-O-Trimethyladenosine is structurally similar to guanosine and cytidine and can be modified by nature or synthetic strategies. N6,N6,2'-O-Trimethyladenosine has been shown to have effects on fertility and may be involved in epigenetics as well as tuberculosis. Its role as an epigenetic marker for gene regulation has not been fully determined.</p>Formula:C13H19N5O4Purity:Min. 88 Area-%Color and Shape:White PowderMolecular weight:309.32 g/mol4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine
CAS:<p>4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine (DdeO) is a novel phosphoramidite that is synthesized from 2’,3’-dideoxycytidine. It is used in DNA synthesis and as an antiviral and anticancer agent. DdeO has shown to be a potent activator of the p53 tumor suppressor gene and inhibits the proliferation of human cancer cells by inhibiting the activity of DNA polymerase alpha. DdeO also inhibits viral replication by interfering with viral DNA synthesis.</p>Purity:Min. 95%5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2'-O-MOE-G(iBu)-CEP, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.</p>Formula:C47H60N7O10PPurity:Min. 95%Color and Shape:White PowderMolecular weight:913.99 g/mol5'-O-tert-Butyldimethylsilyl-D3-thymidine
Controlled Product<p>5'-O-tert-Butyldimethylsilyl-D3-thymidine is a synthetic nucleoside, labeled with the radioactive isotope carbon-14. It is used as an antiviral agent in the treatment of herpes zoster and other viral infections. 5'-O-tert-Butyldimethylsilyl-D3-thymidine is a novel monophosphate, which can be activated to a diphosphate by either kinases or phosphoramidites. It has been shown to be effective against herpes virus and other DNA viruses that infect cells from various species. This drug also has antiviral activity against HIV, although it is not currently approved for this use by the U.S. Food and Drug Administration (FDA).</p>Formula:C16H25N2O5SiD3Purity:Min. 95%Molecular weight:359.52 g/mol4’-Cyanouridine
CAS:<p>4’-Cyanouridine is a nucleoside that is used in the synthesis of DNA and RNA. It is often used as a precursor in the production of phosphoramidites and nucleosides, which are important for DNA synthesis. 4’-Cyanouridine can be used to inhibit viral replication by blocking the activity of reverse transcriptase, an enzyme required for the synthesis of viral DNA. 4’-Cyanouridine can also be used to treat cancer cells by preventing the growth of cells. This compound has been shown to activate RNA polymerase II, which is required for protein synthesis and cell division. The high purity and novel nature of this product make it ideal for use in research laboratories or other specialized settings where high quality products are required.</p>Purity:Min. 95%2',5'-Dideoxyuridine
CAS:<p>2',5'-Dideoxyuridine is a synthetic nucleoside analog derived from uridine, one of the four standard nucleosides found in RNA. It is chemically modified by the removal of hydroxyl (–OH) groups at the 2' and 5' positions of the sugar, altering its ability to participate in RNA or DNA chain formation.</p>Formula:C9H12N2O4Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:212.21 g/molN6-Benzoyl-5'-O-2'-deoxyadenosine
<p>N6-Benzoyl-5'-O-2'-deoxyadenosine is a modified nucleoside that contains a benzoyl group. This nucleoside has been shown to be an antiviral and anticancer agent, and is also active against herpes simplex virus type 1 (HSV1). N6-Benzoyl-5'-O-2'-deoxyadenosine may be a potential therapeutic for the treatment of HSV1 infection. It is also believed to have anti-inflammatory properties. The synthesis of this compound can be achieved by reacting 5'-O-tetraisopropyldiphenylphosphoramidite with benzoyl chloride in the presence of triethylamine.</p>Formula:C36H31N5O4Purity:Min. 95%Molecular weight:597.66 g/mol1', 2', 3', 4', 5'- ¹³C5-Adenosine
CAS:<p>1', 2', 3', 4', 5'- ¹³C5-Adenosine is adenosine which has all five carbon atoms of the ribose sugar replaced with the stable isotope carbon-13 (^13C). Possible applications are in proteomics studies.</p>Formula:C5C5H13N5O4Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:272.2 g/mol5’-O-DMT-N6-(2-phenoxyacetyl)-adenosine
CAS:<p>5’-O-DMT-N6-(2-phenoxyacetyl)-adenosine is a nucleoside monophosphate that is used in the synthesis of DNA, RNA, and phosphoramidites. It has antiviral and anticancer properties and has been shown to inhibit the growth of human cancer cells. 5' -O-DMT-N6-(2-phenoxyacetyl)-adenosine is a novel nucleoside that has been modified to increase its stability. The synthesis of this compound can be carried out with high purity, making it an ideal product for research purposes.<br>5’ -O-DMT-N6-(2-phenoxyacetyl)-adenosine is a synthetic nucleoside that can be used as an activator in DNA synthesis reactions. This product also exhibits high quality and is available at CAS No. 121076-16-2</p>Purity:Min. 95%
