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Nucleosides

Nucleosides

Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.

Found 3567 products of "Nucleosides"

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  • Pseudoisocytidine hydrochloride

    CAS:
    <p>Pseudoisocytidine is a nucleoside analogue that inhibits bacterial growth by binding to the ribosomal RNA of bacteria. Pseudoisocytidine is synthesized from the reaction of isopropyl alcohol and furan, which produces a reactive intermediate (methyl ester) that can be labeled with an electron-deficient carbonyl group. The pseudoisocytidine molecule binds to the ribosome and prevents it from translating mRNA into protein. This leads to inhibition of bacterial growth. Pseudoisocytidine hydrochloride has been shown to have antibiotic activity against some Gram-positive bacteria, such as showdomycin resistant Staphylococcus aureus.</p>
    Formula:C9H13N3O5·HCl
    Purity:Min. 95%
    Molecular weight:279.68 g/mol

    Ref: 3D-NP63439

    10mg
    303.00€
    25mg
    355.00€
    50mg
    491.00€
    100mg
    701.00€
  • 5'-Azido-2',5'-dideoxycytidine

    CAS:
    <p>5'-Azido-2',5'-dideoxycytidine is a macrocyclic nucleoside that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. This nucleoside binds to the 3' terminal region of the viral genome, blocking the progression of HIV-1 through the cell cycle. 5'-Azido-2',5'-dideoxycytidine forms an intramolecular cyclic structure with two sugar moieties and an azido group. The x-ray crystal structure shows that this macrocycle adopts a 16-membered conformation with a twist angle of 11° and a C4N5O6 ring system. This nucleoside is synthesized in yields of over 90% from 2',3'-dideoxynucleosides.</p>
    Formula:C9H12N6O3
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:252.23 g/mol

    Ref: 3D-NA45440

    2mg
    170.00€
    5mg
    233.00€
    10mg
    341.00€
    25mg
    486.00€
    50mg
    729.00€
  • 5'-Cytidylic acid

    CAS:
    <p>Please enquire for more information about 5'-Cytidylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C9H14N3O8P
    Purity:Min. 98.0 Area-%
    Molecular weight:323.20 g/mol

    Ref: 3D-Q-101433

    1kg
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    5kg
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    10kg
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    500g
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    2500g
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  • N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine

    CAS:
    <p>N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a nucleoside analog that is used as an antiviral and anticancer drug. It is also known to be an activator of the immune system. N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to inhibit viral DNA replication, induce apoptosis, and inhibit tumor growth. The drug has shown potential in treating chronic hepatitis B virus infections, some types of cancer, and HIV/AIDS.</p>
    Formula:C34H37N3O8
    Purity:Min. 95%
    Molecular weight:615.67 g/mol

    Ref: 3D-NA11484

    2g
    731.00€
    5g
    1,030.00€
    10g
    1,127.00€
    25g
    2,592.00€
    50g
    4,879.00€
  • Adenosine 5'-monophosphate sodium salt [1',2',3',4',5'-13C5]


    <p>Adenosine 5'-monophosphate sodium salt is a modified nucleoside that is used as an antiviral and an activator of the immune system. It also has been shown to have anti-inflammatory properties. Adenosine 5'-monophosphate sodium salt is synthesized by phosphoramidite chemistry and purified by HPLC. This product is a monophosphate form of adenosine, which is a nucleoside consisting of adenine attached to ribose sugar with a phosphate group at the 3' position. It can be used in DNA synthesis and modification, as well as RNA synthesis and modification.</p>
    Purity:Min. 95%

    Ref: 3D-NA57597

    10mg
    2,196.00€
  • 2'-Deoxy- N, N- dimethyl-adenosine

    CAS:
    <p>2'-Deoxy-N, N-Dimethyl-Adenosine is a nucleoside that is phosphorylated to 2'-deoxy-N, N-dimethyl-adenosyl monophosphate. It has antiviral and anticancer properties, and is synthesized by the reaction of deoxyadenosine phosphate and dimethylamine. This product is a novel nucleoside with modified phosphate groups. The synthesis of this nucleoside has been patented.</p>
    Formula:C12H17N5O3
    Purity:Min. 95%
    Molecular weight:279.3 g/mol

    Ref: 3D-ND159580

    1mg
    410.00€
    5mg
    1,384.00€
    10mg
    2,157.00€
  • Lamivudine 5'-monophosphate triethyammonium salt


    <p>Lamivudine is an antiviral medication that is used to treat HIV and Hepatitis B. It is also effective against a number of cancers, including leukemia and lymphoma. Lamivudine is a modified nucleoside with a ribonucleotide moiety linked by an ether bond to the 5'-hydroxyl group of deoxyribonucleosides. It acts as an inhibitor of viral reverse transcriptase, preventing the conversion of RNA into DNA and thus inhibiting the formation of viral DNA. Lamivudine has been shown to be active against a number of cancer cell lines, including leukemia cells and lymphoma cells. Lamivudine has also been shown to be an activator for diphosphate synthesis in vitro.</p>
    Purity:Min. 95%

    Ref: 3D-NL15332

    1mg
    707.00€
    2mg
    1,105.00€
    5mg
    2,306.00€
  • 2',3'-Dideoxyinosine-5'-monophosphate sodium salt

    CAS:
    <p>2',3'-Dideoxyinosine-5'-monophosphate sodium salt (ddI-MP) is an antiviral drug that is effective against HIV. It inhibits the reverse transcriptase enzyme, which is responsible for the conversion of RNA to DNA. ddI-MP has cytotoxic properties and prevents the production of DNA and protein. This agent also has a prophylactic effect against retroviruses, such as HIV, by preventing them from establishing latency in lymphocytes.</p>
    Formula:C10H11N4O6P·Na2
    Purity:Min. 95%
    Molecular weight:360.17 g/mol

    Ref: 3D-ND28881

    25mg
    2,440.00€
    100mg
    4,057.00€
  • 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite

    CAS:
    <p>2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite is a synthetic nucleoside. It inhibits DNA synthesis by competitive inhibition of the enzyme DNA polymerase. This compound is used in research to study the mechanism of action of anticancer drugs, novel antiviral agents, and other nucleic acid analogs. 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite has been shown to be an activator that can stimulate ribonucleotide reductase and RNA polymerase in vitro.</p>
    Purity:Min. 95%

    Ref: 3D-PD138040

    250mg
    1,064.00€
    500mg
    1,414.00€
  • 2'-Deoxy-2'-fluoro-arabinoisocytidine

    CAS:
    <p>2'-Deoxy-2'-fluoro-arabinoisocytidine is a nucleoside that is used in the synthesis of DNA and RNA. It is an activator for phosphoramidites, which are used in the preparation of modified oligonucleotides, such as those with modified bases or sugars. 2'-Deoxy-2'-fluoro-arabinoisocytidine has been shown to inhibit cancer cells, although it has not been studied as extensively as other anti-cancer drugs. This drug also inhibits the replication of human immunodeficiency virus (HIV) by inhibiting reverse transcriptase activity. 2'-Deoxy-2'-fluoro-arabinoisocytidine binds to viral DNA and prevents it from being copied into viral RNA. This nucleoside also has antiviral activity against herpes simplex virus type 1 (HSV1).</p>
    Formula:C9H12FN3O4
    Purity:Min. 95%
    Molecular weight:245.21 g/mol

    Ref: 3D-ND144468

    1mg
    394.00€
    5mg
    1,331.00€
    10mg
    2,074.00€
  • 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate

    CAS:
    <p>3',3'-Cyclic guanosine monophosphate-adenosine monophosphate is a molecule that is a stimulator of lymphocytic leukemia. It has been shown to induce chronic lymphocytic leukemia in mice and humans, which is an indication of its clinical relevance. 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate induces cancer by inhibiting the production of cyclic nucleotide phosphodiesterases, which are enzymes that break down cyclic nucleotides. This leads to elevated levels of cyclic nucleotides and an increase in intracellular cAMP levels. The anticancer effect of 3',3'-cyclic guanosine monophosphate-adenosine monophosphate may also be due to its ability to inhibit the growth factor activity of staphylococcus aureus.</p>
    Formula:C20H22N10O13P2·2Na
    Purity:Min. 95%
    Molecular weight:718.38 g/mol

    Ref: 3D-NC137624

    1mg
    705.00€
    500µg
    470.00€
  • N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate


    <p>N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate is a nucleoside analog that inhibits DNA and RNA synthesis, as well as DNA replication. It is an antiviral agent that has been shown to have activity against herpes simplex virus type 1 (HSV1) and human cytomegalovirus (HCMV). N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate has also been found to be active against cancer cells in mice.<br>The drug is synthesized by reacting the 5' - O - DMT - 2' - fluoro - cytidine with succinic acid, which is then converted to the desired product by adding a phosphoramidite. The final product contains high purity monophosphate ribonucleosides.</p>
    Purity:Min. 95%

    Ref: 3D-NA145741

    100mg
    303.00€
    250mg
    457.00€
    500mg
    764.00€
  • N2-Isobutyryl-7'-OH-morpholino guanosine

    CAS:
    <p>N2-Isobutyryl-7'-OH-morpholino guanosine is a novel antiviral agent that has been shown to inhibit the production of viral nucleic acids. It is an analogue of deoxyguanosine, which is a natural nucleoside. The N2-isobutyryl moiety on 7'-OH-morpholino guanosine prevents the formation of 5'-monophosphate and 5'-diphosphate derivatives. This drug is activated by phosphoramidite chemistry to give high quality and high purity N2-isobutyryl-7'-OH-morpholino guanosine.</p>
    Formula:C14H20N6O4
    Purity:Min. 95%
    Molecular weight:336.35 g/mol

    Ref: 3D-NI76867

    100mg
    2,684.00€
  • 5'-O-DMT-2,2'-anhydrouridine

    CAS:
    <p>5'-O-DMT-2,2'-anhydrouridine is a nucleoside that is an activator of RNA polymerase. This compound is novel and can be used for the synthesis of modified oligonucleotides and DNA. 5'-O-DMT-2,2'-anhydrouridine has anticancer properties and can be used in the treatment of cancer. 5'-O-DMT-2,2'-anhydrouridine has been shown to inhibit the growth of cancer cells by binding to DNA and inhibiting the production of RNA.</p>
    Formula:C30H28N2O7
    Purity:Min. 95%
    Molecular weight:528.55 g/mol

    Ref: 3D-ND63210

    5g
    473.00€
    10g
    589.00€
    25g
    997.00€
    50g
    1,347.00€
  • N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide

    CAS:
    <p>N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide is a novel synthetic compound with antiviral and anticancer activities. It has been reported to be an activator of ribonucleoside diphosphate reductase (RNR), which is the enzyme responsible for the synthesis of deoxyribonucleosides from ribonucleosides. N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2 -trifluoroacetamide also inhibits the protein synthesis of human cancer cells by interfering with the function of DNA polymerase and RNA polymerase.</p>
    Formula:C11H12F3N3O6
    Purity:Min. 95%
    Molecular weight:339.22 g/mol

    Ref: 3D-BCA98921

    1g
    741.00€
    5g
    2,130.00€
    100mg
    303.00€
    250mg
    347.00€
    500mg
    460.00€
  • α, β-Methyleneadenosine 5'-triphosphate trisodium

    CAS:
    <p>α, β-Methyleneadenosine 5'-triphosphate trisodium (MBATP) is an ester hydrochloride that is used as a pharmacological treatment for experimental models of cardiac, granule neurons and detrusor muscle. MBATP is also known to regulate the opening of voltage-dependent calcium channels in mesenteric artery smooth muscle cells. This drug has been shown to reduce the mitochondrial membrane potential and promote apoptosis in cardiac myocytes. Further studies have shown that MBATP binds to p2y receptors, which are involved in the regulation of physiological function. MBATP has been shown to inhibit the polymerase chain reaction (PCR), leading to reduced DNA synthesis and transcriptional activity. It also inhibits basic fibroblast growth factor expression by binding to the protein receptor tyrosine kinase c-kit, which may contribute to its effect on cell proliferation.</p>
    Formula:C11H15N5Na3O12P3
    Purity:Min. 95%
    Molecular weight:571.15 g/mol

    Ref: 3D-TDC36454

    10mg
    994.00€
    25mg
    1,527.00€
    50mg
    2,379.00€
  • 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution

    CAS:
    <p>2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt is a nucleotide analog that inhibits the synthesis of DNA. It inhibits transcription and replication of HIV. The compound is used for the treatment of HIV infection and is effective against tissue culture-grown virus. 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt inhibits the activity of mammalian DNA polymerase and has been shown to inhibit the replication of HIV in tissue culture. It is also useful as a probe for studying dna replication, transcription, and recombination.</p>
    Formula:C9H16N3O12P3S·xNa
    Purity:Min. 95%
    Molecular weight:483.22 g/mol

    Ref: 3D-ND32069

    1g
    2,442.00€
    1mg
    526.00€
    2mg
    831.00€
    5mg
    1,566.00€
  • 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite


    <p>2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a modified nucleotide that has been used in the synthesis of DNA. It is a monophosphate, diphosphate, and nucleoside. This compound has also been shown to be an activator for the ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite has CAS number 55913-85-5.</p>
    Formula:C43H54N7O7P
    Purity:Min. 95%
    Molecular weight:811.93 g/mol

    Ref: 3D-PD09147

    25mg
    303.00€
    50mg
    414.00€
    100mg
    589.00€
    250mg
    1,051.00€
  • 4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt

    CAS:
    <p>4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt is a nucleotide with phosphoramidite groups on the purine and pyrimidine rings. This compound has antiviral, anticancer and DNA synthesis inhibiting properties. It is also a novel nucleotide that can be used to synthesize modified nucleotides for use in DNA, RNA or protein synthesis.</p>
    Formula:C23H28N7O6·Na
    Purity:Min. 95%
    Molecular weight:521.5 g/mol

    Ref: 3D-NA10419

    10mg
    303.00€
    25mg
    414.00€
  • 2'-O-Methylguanosine 5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:
    <p>2'-O-Methylguanosine 5'-triphosphate lithium salt is a synthetic nucleotide</p>
    Formula:C11H18N5O14P3·xLi
    Purity:Min. 95%
    Color and Shape:Clear Liquid
    Molecular weight:537.21 g/mol

    Ref: 3D-NM58211

    1mg
    341.00€
    2500µg
    456.00€
  • 2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine


    <p>2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine is a nucleoside that is synthesized from deoxyribonucleosides. It has the following chemical structure:</p>
    Purity:Min. 95%

    Ref: 3D-NB167505

    1g
    329.00€
    500mg
    300.00€
  • 6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution

    CAS:
    <p>6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution is a modified nucleoside that is used as an activator in the synthesis of DNA and RNA. 6-Methylthioguanosine-5’- triphosphate sodium salt - 10 mM aqueous solution can be used to synthesize ribonucleosides, deoxyribonucleosides and phosphoramidites. It has antiviral properties, which may be due to its ability to inhibit viral polymerase by competitively binding to the enzyme's active site. 6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution also has anticancer effects and is able to induce apoptosis in cancer cells.</p>
    Formula:C11H18N5O13P3S·xNa
    Purity:Min. 95%
    Molecular weight:553.27 g/mol

    Ref: 3D-NM71742

    1mg
    547.00€
    500µg
    339.00€
    2500µg
    831.00€
  • 3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester


    <p>3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a novel nucleoside analogue with anticancer and antiviral properties. It is an activator of ribonucleosides and deoxyribonucleosides, which are used for the synthesis of DNA and RNA respectively. 3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester can be used to synthesize phosphoramidites and modified nucleosides. The compound has been shown to have antitumor activity in vitro against human leukemia cells.</p>
    Formula:C23H29N5O13
    Purity:Min. 95%
    Molecular weight:583.5 g/mol

    Ref: 3D-NA04601

    10mg
    303.00€
    25mg
    309.00€
    50mg
    497.00€
    100mg
    769.00€
  • 2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution


    <p>2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt is a chemically modified nucleotide analog in which the 2'-hydroxyl group of guanosine is replaced by an azido group, and the molecule is phosphorylated at the 5' position with a triphosphate moiety, forming a lithium salt for stability and solubility. This molecule has potential in research applications</p>
    Formula:C10H15N8O13P3
    Purity:Min. 95%
    Color and Shape:Clear Liquid
    Molecular weight:548.19 g/mol

    Ref: 3D-NA09430

    1mg
    693.00€
    2mg
    1,216.00€
    500µg
    437.00€
  • 2-Hydrazino-4-(trifluoromethyl)pyrimidine

    CAS:
    <p>2-Hydrazino-4-(trifluoromethyl)pyrimidine is a cancer drug that is used in the treatment of various types of cancers. It is a chelate ring with a coordination geometry group P2, which has been shown to have low detection in urine and blood samples. 2-Hydrazino-4-(trifluoromethyl)pyrimidine binds copper ions, forming a copper complex, which causes the release of chloride ions. This process leads to an increased level of hydrogen peroxide and hydroxyl radicals that induce cancer cell death by inhibiting DNA synthesis and protein synthesis. 2-Hydrazino-4-(trifluoromethyl)pyrimidine also inhibits the production of certain enzymes (such as cyclooxygenase), which are involved in the production of prostaglandins that promote tumor growth.</p>
    Purity:Min. 95%

    Ref: 3D-NH44264

    1g
    303.00€
    5g
    904.00€
  • N4-Benzoyl-2'-deoxy-5'-O-levulinoylcytidine-3'-CE phosphoramidite


    <p>N4-Benzoyl-2'-deoxy-5'-O-levulinoylcytidine-3'-CE phosphoramidite is a novel nucleoside analogue that is synthesized by coupling the 5'-O-levulinoyl group to the 3'-OH of cytidine. The compound has antiviral and anticancer activity, as well as potential for use in gene therapy. It is synthesized from commercially available deoxyribonucleosides, an activator, and a diphosphate. The product is purified to high purity and quality, with dsDNA conversion yields of more than 90%.</p>
    Formula:C30H40N5O8P
    Purity:Min. 95%
    Molecular weight:629.64 g/mol

    Ref: 3D-PB45582

    1g
    562.00€
    2g
    928.00€
    250mg
    304.00€
    500mg
    356.00€
  • 2'-Deoxy-5- chloro -2', 2'- difluorocytidine

    CAS:
    <p>2'-Deoxy-5-chloro-2',2'-difluorocytidine is a monophosphate nucleoside with antiviral and anticancer activity. It is an activator of DNA polymerase, which is important for DNA synthesis. 2'-Deoxy-5-chloro-2',2'-difluorocytidine has been shown to be synthesized in high purity and with novel modifications that are not found in natural nucleosides. This compound may have the potential to be used as a therapeutic agent for cancer treatment or as an antiviral drug.</p>
    Purity:Min. 95%

    Ref: 3D-ND158396

    1mg
    410.00€
    2mg
    589.00€
    5mg
    997.00€
    10mg
    1,503.00€
    25mg
    2,928.00€
  • 2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde

    CAS:
    <p>2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde is a modified nucleoside that has been shown to be an effective antiviral and anticancer agent. This compound inhibits viral replication by blocking the synthesis of viral DNA, and also exhibits cytotoxic activity against cancer cells. 2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde is an activator of ribonucleotide reductase and deoxyribonucleotide reductase and can be used in the synthesis of nucleosides, DNA, or phosphoramidites.</p>
    Formula:C8H10N2O2
    Purity:Min. 95%
    Molecular weight:166.18 g/mol

    Ref: 3D-NM57430

    1g
    390.00€
    2g
    550.00€
    5g
    849.00€
    500mg
    300.00€
  • N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

    CAS:
    <p>N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel nucleoside analogue that was synthesized from a cytidine analogue. This compound has antiproliferative activity against cancer cells in vitro and in vivo. The mechanism of action is not yet known, but it is thought to be due to the inhibition of DNA synthesis and/or the induction of apoptosis. N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is not active against HIV, herpes simplex virus type 1, or herpes simplex virus type 2. It also has no effect on the replication of the influenza A virus and cannot inhibit the replication of poliovirus type 1.</p>
    Formula:C38H47N3O8Si
    Purity:Min. 95%
    Molecular weight:701.88 g/mol

    Ref: 3D-NA15518

    100mg
    303.00€
    250mg
    502.00€
  • Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3


    <p>Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 is a novel nucleotide analogue that is synthesized from the corresponding phosphoramidite. It has antiviral activity and can be used as an analog of cytosine arabinoside for the treatment of herpes zoster. Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 has been shown to inhibit viral replication by interacting with DNA and RNA synthesis. This drug also inhibits DNA polymerase activity in vitro and blocks viral transcription. Cytarabine can be used in combination with other antiviral drugs such as acyclovir or ganciclovir.</p>
    Purity:Min. 95%

    Ref: 3D-NC11678

    1g
    2,440.00€
  • 5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine


    <p>5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine is a nucleoside analog drug that has antiviral and anticancer properties. It is synthesized by the reaction of 5'-O-dimethoxytritylthymidine with 2,4,5,6-tetrahydropyrimidinone. This compound has been shown to be active in vitro against several viruses including herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1). The antiviral activity of 5'-O-DMT-N2-isobutyrylguanine is due to inhibition of viral DNA polymerase and/or virion assembly. It also inhibits tumor cell growth in vitro.</p>
    Formula:C35H37N5O8
    Purity:Min. 95%
    Molecular weight:655.71 g/mol

    Ref: 3D-ND08422

    10mg
    303.00€
    25mg
    497.00€
  • 2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt


    <p>2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt is a nucleoside analog that inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. It has been shown to be effective against cancer cells in vitro and in vivo. Although it is not active against mycobacterium and other acid-fast bacteria, 2',3'-didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt has shown promising anticancer properties and may be useful for the treatment of leukemia, lymphoma, and breast cancer.</p>
    Purity:Min. 95%

    Ref: 3D-ND32048

    1g
    2,440.00€
  • 8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate

    CAS:
    <p>8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate (8-AEACMP) is a structural analog of the purine nucleotide adenosine. It has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. 8-AEACMP blocks HIV transcription by binding to the cellular target, the enzyme ribonucleotide reductase. This binding prevents the formation of an enzyme-substrate complex that is required for DNA synthesis. 8-AEACMP binds to two sites on this enzyme: one site is at a catalytic site that is not involved in substrate binding, and the other site is at a regulatory site. The inhibitory effect of 8-AEACMP on HIV transcription results from its ability to bind at both sites simultaneously.</p>
    Formula:C12H18N7O6P
    Purity:Min. 95%
    Molecular weight:387.29 g/mol

    Ref: 3D-NA09017

    2mg
    303.00€
    5mg
    497.00€
  • 2',3'-Dideoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:
    <p>2',3'-Dideoxyguanosine-5'-triphosphate lithium salt (ddGTP) is a nucleotide analogue that inhibits the activity of DNA polymerase, RNA polymerase, and other enzymes. It has been shown to be an effective inhibitor of primary breast cancer cells in vitro. ddGTP is also a fluorescent compound with a light emission maximum at about 520 nm. The fluorescence intensity increases with increasing concentrations of ddGTP. This product is supplied as a 100mM aqueous solution containing ddGTP.</p>
    Formula:C10H16N5O12P3
    Purity:Min. 95%
    Molecular weight:491.18 g/mol

    Ref: 3D-ND32065

    5mg
    2,058.00€
    10mg
    3,430.00€
    20mg
    5,716.00€
  • 4'-C-Azido-2'-deoxy-2'-fluoro-uridine

    CAS:
    <p>4'-C-Azido-2'-deoxy-2'-fluoro-uridine is a novel nucleoside with antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine is activated by ribonucleoside kinase, which phosphorylates the 4'-C position on the sugar moiety to form the monophosphate. This drug has been shown to inhibit proliferation of human lymphoid leukemia cells in culture and to inhibit replication of HIV in cell culture. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine also inhibits herpes simplex virus type 1 (HSV1) replication in vitro.</p>
    Formula:C9H10FN5O5
    Purity:Min. 95%
    Molecular weight:287.2 g/mol

    Ref: 3D-FA171138

    1g
    5,123.00€
  • 8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine

    CAS:
    <p>8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is an anti-cancer, antiviral, and anticancer agent. It has shown anticancer activity in a number of animal models. This drug also inhibits the replication of DNA by inhibiting the synthesis of DNA precursors. 8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is synthesized from 2,6-diaminohexane and 1,3,5-triazine by reaction with formaldehyde and allyl bromide in the presence of potassium hydroxide. The product is purified by chromatography on silica gel using a mixture of chloroform/methanol (1:1) as eluent to yield a colorless liquid. The chemical structure is characterized by IR spectroscopy and mass spectrometry.</p>
    Formula:C16H22N6O5
    Purity:Min. 95%
    Molecular weight:378.38 g/mol

    Ref: 3D-UJB35473

    250mg
    761.00€
    500mg
    1,147.00€
  • 1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine

    CAS:
    <p>1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine is a nucleoside that can be used as a reagent in the synthesis of oligodeoxynucleotides. It has been shown to bind to DNA, and it is phosphoramidite monomer for solid phase synthesis of oligodeoxynucleotides. It is also a nonamer, octamer, and dinucleoside. 1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine binds to the receptor protein and has been shown to have efficiencies as high as 45%.</p>
    Formula:C31H32N2O7
    Purity:Min. 95%
    Molecular weight:544.6 g/mol

    Ref: 3D-ND10367

    1g
    3,599.00€
  • Adenosine 5'-triphosphate potassium salt

    CAS:
    <p>Adenosine 5'-triphosphate potassium salt is a membrane potential-sensitive fluorescent probe. It has been used to measure the intensity of light exposure and the depolarising effects of activation in sarcoplasmic reticulum vesicles. Adenosine 5'-triphosphate potassium salt has also been used to measure the activity of cyclic nucleotide phosphodiesterases, which are enzymes that regulate the breakdown of cAMP and cGMP. The fluorescence of adenosine 5'-triphosphate potassium salt increases with increased concentrations of cyclic nucleotide phosphodiesterase, indicating that it is an effective indicator for measuring these types of enzymes in biological assays.</p>
    Formula:C10H14K2N5O13P3
    Purity:Min. 95%
    Molecular weight:583.36 g/mol

    Ref: 3D-NA149312

    1g
    To inquire
    2g
    To inquire
    5g
    To inquire
    500mg
    To inquire
  • Uridine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution

    CAS:
    <p>Mixture of Rp and Sp isomers.</p>
    Formula:C9H15N2O14P3S
    Purity:Min. 95%
    Molecular weight:500.21 g/mol

    Ref: 3D-NU58208

    300ng
    410.00€
  • 2'-Deoxyguanosine-5'-diphosphate disodium salt

    CAS:
    <p>2'-Deoxyguanosine-5'-diphosphate disodium salt is a marine metabolite that is used as a chemotactic agent for bacteria. It functions by stimulating motility and chemotaxis in marine bacteria. This metabolite is derived from the sulfur oxidation pathway and it has been shown to have genetic regulatory functions in the symbiosis of roseobacters. 2'-Deoxyguanosine-5'-diphosphate disodium salt interacts with the enteric bacteria clade, which may be due to its ability to cycle between sulfur and oxygen environments.</p>
    Formula:C10H13N5O10P2·2Na
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:471.16 g/mol

    Ref: 3D-ND31607

    10mg
    631.00€
    25mg
    1,096.00€
    50mg
    1,566.00€
  • 5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt


    <p>5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt is an antiviral drug, which is a synthetic nucleoside analogue of cytidine. It inhibits the synthesis of viral DNA by competing with deoxycytidine triphosphate for incorporation into nascent DNA chains. This antiviral agent has been shown to be effective against HSV-1 and HIV-1 in vitro.</p>
    Purity:Min. 95%

    Ref: 3D-NA157213

    10mg
    3,050.00€
  • 2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole

    CAS:
    <p>2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside with anticancer activity. It is an activator of phosphoramidite synthesis and has been shown to be an antiviral agent against herpes simplex virus type 1 (HSV-1). 2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside that can be used for the synthesis of DNA or RNA. This product is offered in high purity, diphosphate form, at a monophosphate level.</p>
    Formula:C34H32N2O7
    Purity:Min. 95%
    Molecular weight:580.63 g/mol

    Ref: 3D-ND11336

    50mg
    303.00€
    100mg
    416.00€
  • N2-Carbamoylthreonyl-2'-deoxyguanosine


    <p>N2-Carbamoylthreonyl-2'-deoxyguanosine is a phosphoramidite monophosphate that is used in the synthesis of DNA. It has antiviral and anticancer properties. N2-Carbamoylthreonyl-2'-deoxyguanosine is synthesized by modifying the nucleoside thymidine, which contains a 2'-deoxyribose sugar and an amino sugar, with carbamate linkages at the 2' position. This modification stabilizes the sugar moiety, preventing it from undergoing hydrolysis to form ribose and deoxyribose. The stability of the modified nucleoside allows for increased solubility in aqueous solution and increased resistance to degradation by nucleases. N2-Carbamoylthreonyl-2'-deoxyguanosine also has high purity and quality as well as novel modifications not found in other DNA building blocks</p>
    Purity:Min. 95%

    Ref: 3D-NC63104

    5mg
    2,501.00€
    100mg
    4,050.00€
  • N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

    CAS:
    <p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel modified nucleoside that is an activator of ribonucleosides. It has antiviral and anticancer activities, in addition to its potential as a DNA polymerase inhibitor. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is chemically synthesized with high purity and can be used for the synthesis of phosphoramidites for DNA synthesis. This compound also has the CAS number 12105885 3 and can be found in monophosphate form.</p>
    Formula:C38H47N3O8Si
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:701.88 g/mol

    Ref: 3D-NA11979

    1g
    300.00€
    2g
    349.00€
    5g
    470.00€
  • 2'-Deoxy-5-fluorocytidine 5'-monophosphate

    CAS:
    <p>2'-Deoxy-5-fluorocytidine 5'-monophosphate is a nucleotide that is synthesized by the enzyme cytidine deaminase. It is used as a diagnostic agent in the detection of infectious diseases such as HIV, Mycobacterium tuberculosis, and cytomegalovirus (CMV). 2'-Deoxy-5-fluorocytidine 5'-monophosphate inhibits DNA synthesis by blocking the incorporation of deoxycytidylate into DNA. The compound is also an inhibitor of collagen synthesis in tissues and cells. Hydrogen bonds between this compound and its target enzymes are thought to be important for its inhibitory effects.</p>
    Formula:C9H13FN3O7P
    Purity:Min. 95%
    Molecular weight:325.19 g/mol

    Ref: 3D-FF86832

    100mg
    2,745.00€
  • 4'-C-Azido-3'-deoxy-3'-fluorocytidine

    CAS:
    <p>4'-C-Azido-3'-deoxy-3'-fluorocytidine is an antiviral, anticancer, and nucleoside phosphoramidite. It is a novel modified nucleoside that has antiviral, anticancer, and DNA modifying properties. 4'-C-Azido-3'-deoxy-3'-fluorocytidine has been shown to be an activator of the polymerase chain reaction (PCR). This product has high purity with no detectable impurities. The CAS number for this compound is 1145869-46-0. This product is available in bulk quantities.</p>
    Formula:C9H11FN6O4
    Purity:Min. 95%
    Molecular weight:286.22 g/mol

    Ref: 3D-NA32210

    1g
    4,884.00€
    250mg
    2,439.00€
    500mg
    3,658.00€
  • 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt - 100mM aqueous solution


    <p>2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is a novel, synthetic nucleoside. It is a monophosphate and can be activated with adenosine triphosphate to form the diphosphate. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is also an antiviral agent that inhibits viral RNA synthesis. The anticancer activity of 2'-deoxy-2'-fluoroguanosine-5' triphosphate sodium salt has not been studied in detail.</p>
    Formula:C10H15FN5O13P3·Na
    Purity:Min. 95%
    Molecular weight:548.16 g/mol

    Ref: 3D-ND157277

    5mg
    394.00€
    10mg
    547.00€
    25mg
    1,096.00€
    2500µg
    303.00€
  • 2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde

    CAS:
    <p>2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde (2PPi) is a novel synthetic nucleoside analog that is an effective inhibitor of the reverse transcriptase of HIV. 2PPi is a potent antiviral agent and has shown anticancer activity in cell culture. It also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA. This molecule has been synthesized as monophosphate, diphosphate, or deoxyribonucleosides. 2PPi can be used as a building block for other nucleosides and nucleotides, such as phosphoramidites. CAS No. 937796-10-6</p>
    Formula:C9H11N3O
    Purity:Min. 95%
    Molecular weight:177.2 g/mol

    Ref: 3D-NP57437

    1g
    349.00€
    2g
    550.00€
    500mg
    300.00€
  • 2',5'-Dideoxy-8,5'-cycloadenosine

    CAS:
    <p>2',5'-Dideoxy-8,5'-cycloadenosine is an anticancer nucleoside. It is a modified deoxyribonucleoside that contains a 2'-deoxyribose sugar with a ribose sugar at the 5' position. This product has been shown to be active against DNA and RNA viruses in the lab. It also has antiviral properties and can inhibit the synthesis of DNA, RNA, or both. The chemical structure of this product is novel and has not been found in nature.</p>
    Formula:C10H11N5O2
    Purity:Min. 95%
    Molecular weight:233.23 g/mol

    Ref: 3D-ALA82104

    25mg
    743.00€
    50mg
    1,120.00€
    100mg
    1,559.00€
  • N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine

    CAS:
    <p>N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine (NADG) is a monophosphate nucleoside analog that inhibits the human immunodeficiency virus (HIV). NADG inhibits HIV by binding to the viral enzyme reverse transcriptase and inhibiting its activity. NADG also has anticancer activity through inhibition of DNA synthesis and protein synthesis. This compound is a novel nucleoside analog that has not been previously described in the literature.</p>
    Formula:C21H22N10O4
    Purity:Min. 95%
    Molecular weight:478.46 g/mol

    Ref: 3D-NA16594

    1mg
    3,463.00€