G-protein Coupled Receptors and 7-TM Receptors
G-protein coupled receptors (GPCRs) and 7-transmembrane (7-TM) receptors are a large family of membrane proteins that play key roles in cellular communication and signal transduction. These receptors are involved in a wide range of physiological processes, including sensory perception, immune response, and hormone regulation. GPCRs are major targets in drug discovery, making them essential for research in pharmacology and medicine. At CymitQuimica, we offer a comprehensive selection of high-quality reagents and compounds related to GPCRs and 7-TM receptors to support your research and drug development efforts.
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(S)-FTY720-phosphonate
CAS:1142015-10-8
FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, …
Formula:
C20H36NO4P
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
385.48
Ref: TM-T78091
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 5 May 2025
Carmoxirole hydrochloride
CAS:115092-85-8
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity …
Formula:
C24H27ClN2O2
Purity:
97.8% - 98.12%
Color and Shape:
Solid
Molecular weight:
410.94
Ref: TM-T10683
| 1mg | 58.00 € | ||
| 5mg | 117.00 € | ||
| 10mg | 178.00 € | ||
| 25mg | 306.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 620.00 € | ||
| 200mg | 835.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Monday 5 May 2025
CaSR antagonist-1
CAS:1219811-83-2
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration …
Formula:
C29H24FN3O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
497.58
Ref: TM-T79023
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 5 May 2025
TCS 2510
CAS:346673-06-1
TCS 2510 (CAY10598) 是一种选择性 PGE2 和 EP4 受体激动剂,可增强细胞内 cAMP 浓度和活性 β-caten 的丰度。TCS 2510 抑制TNF-α 产生,可用于研究代谢紊乱带来的疾病。
Formula:
C21H29N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
383.49
Ref: TM-T23448
| 1mg | 437.00 € |
Estimated delivery in United States, on Monday 5 May 2025
CCG-63802
CAS:620112-78-9
CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.
Formula:
C26H18N4O2S
Purity:
90%
Color and Shape:
Solid
Molecular weight:
450.51
Ref: TM-T14897
| 2mg | 43.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 180.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Sigma-1 receptor antagonist 1
CAS:1639220-19-1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor.
Formula:
C19H23Cl2N3O
Purity:
99.81%
Color and Shape:
Solid
Molecular weight:
380.31
Ref: TM-T12910
| 1mg | 64.00 € | ||
| 5mg | 145.00 € | ||
| 10mg | 226.00 € | ||
| 25mg | 379.00 € | ||
| 50mg | 538.00 € | ||
| 100mg | 730.00 € | ||
| 200mg | 938.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Bivamelagon hydrochloride
CAS:2641595-55-1
MC-4R Agonist 2 hydrochloride (Example 1) serves as an MC4R agonist, with applications in researching …
Formula:
C35H54Cl2N4O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
665.73
Ref: TM-T79091
| 25mg | 1,872.00 € | ||
| 50mg | 2,452.00 € | ||
| 100mg | 3,230.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Mocravimod hydrochloride
CAS:509088-69-1
Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type …
Formula:
C24H27Cl2NO3S
Purity:
90%
Color and Shape:
Solid
Molecular weight:
480.45
Ref: TM-T12086
| 1mg | 70.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 264.00 € | ||
| 25mg | 535.00 € | ||
| 50mg | 828.00 € | ||
| 100mg | 1,111.00 € | ||
| 1mL*10mM (DMSO) | 172.00 € |
Estimated delivery in United States, on Monday 5 May 2025
AGN 210676
CAS:910562-15-1
AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
Formula:
C23H29NO5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
431.55
Ref: TM-T14146
| 25mg | 1,730.00 € | ||
| 50mg | 2,262.00 € | ||
| 100mg | 2,945.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Crisdesalazine
CAS:927685-43-6
Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1).
Formula:
C16H14F3NO3
Purity:
95.95%
Color and Shape:
Solid
Molecular weight:
325.28
Ref: TM-T27084
| 1mg | 137.00 € | ||
| 2mg | 188.00 € | ||
| 5mg | 329.00 € | ||
| 10mg | 512.00 € | ||
| 25mg | 812.00 € | ||
| 50mg | 1,093.00 € | ||
| 100mg | 1,473.00 € |
Estimated delivery in United States, on Monday 5 May 2025
TM-N1324
CAS:1144477-35-9
TM-N1324 is a GPR39 agonist; 280 nM potency without Zn2+, 9 nM with; similar effects …
Formula:
C18H13ClFN7O
Purity:
90.39%
Color and Shape:
Solid
Molecular weight:
397.79
Ref: TM-T17103
| 1mg | 52.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 393.00 € | ||
| 50mg | 587.00 € | ||
| 100mg | 835.00 € | ||
| 1mL*10mM (DMSO) | 97.00 € |
Estimated delivery in United States, on Monday 5 May 2025
Vasopressin
CAS:11000-17-2
Vasopressin receptor agonist; antidiuretic
Formula:
C46H65N15O12S2
Purity:
Min. 95%
Color and Shape:
White Powder
Molecular weight:
1,084.23 g/mol
Ref: 3D-FV40959
| 1g | 1,252.00 € | ||
| 50mg | 334.00 € | ||
| 100mg | 471.00 € | ||
| 250mg | 698.00 € | ||
| 500mg | 932.00 € |
Estimated delivery in United States, on Monday 12 May 2025
LGD-6972
CAS:1207989-09-0
LGD-6972 is an antagonist of glucagon receptor.
Formula:
C43H46N2O5S
Purity:
98.8% - 99.33%
Color and Shape:
Solid
Molecular weight:
702.9
Ref: TM-T11845
| 1mg | 88.00 € | ||
| 5mg | 187.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 472.00 € | ||
| 50mg | 692.00 € | ||
| 100mg | 938.00 € | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Monday 12 May 2025
AMG 837 calcium hydrate
CAS:1259389-38-2
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM.
Formula:
C52H44CaF6O8
Purity:
98.07%
Color and Shape:
Solid
Molecular weight:
950.97
Ref: TM-TQ0020
| 2mg | 37.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 284.00 € | ||
| 100mg | 415.00 € | ||
| 200mg | 567.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 19 May 2025
Lumateperone
CAS:313368-91-1
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).
Formula:
C24H28FN3O
Purity:
99.77%
Color and Shape:
Solid
Molecular weight:
393.5
Ref: TM-T21069
| 10mg | 39.00 € | ||
| 25mg | 58.00 € | ||
| 50mg | 85.00 € | ||
| 100mg | 116.00 € |
Estimated delivery in United States, on Monday 19 May 2025
PSB 1115
CAS:152529-79-8
PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.
Formula:
C14H14N4O5S
Purity:
100% - 99.24%
Color and Shape:
Solid
Molecular weight:
350.35
Ref: TM-T23201
| 1mg | 66.00 € | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 19 May 2025
SB-616234-A
CAS:908601-49-0
SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant …
Formula:
C32H36ClN5O3
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
574.11
Ref: TM-T12847
| 1mg | 105.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 557.00 € | ||
| 50mg | 752.00 € | ||
| 100mg | 1,035.00 € | ||
| 200mg | 1,396.00 € | ||
| 1mL*10mM (DMSO) | 321.00 € |
Estimated delivery in United States, on Monday 19 May 2025
SR 142948
CAS:184162-64-9
SR 142948 is a neurotensin (NT) receptor antagonist.
Formula:
C39H51N5O6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
685.85
Ref: TM-T23386
| 10mg | 878.00 € |
Estimated delivery in United States, on Monday 19 May 2025
H-Glu-Thr-OH
CAS:6875-80-5
H-Glu-Thr-OH (L-α-Glutamyl-L-threonine) is a dipeptide composed of two amino acids-glutamic acid (Glu) and threonine (Thr)-linked …
Formula:
C9H16N2O6
Color and Shape:
Liquid
Molecular weight:
248.23
Ref: TM-T201727
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Jun 2025
CS-003 Free base
CAS:191672-52-3
CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats …
Formula:
C34H38Cl2N2O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
673.65
Ref: TM-T10892
| 25mg | 2,442.00 € | ||
| 50mg | 3,212.00 € | ||
| 100mg | 4,370.00 € |
Estimated delivery in United States, on Monday 2 Jun 2025
