Hormones in Recombinant Proteins

<p>Applications Quillaic Acid an unglycosylated saponin from the Quillaja saponaria bark is used as a topical antiinflammatory.<br>References Arrau, S. et al.: J. Ethnopharm., 133, 164 (2011);<br></p>

<p>Applications It is used as cholesterol-lowering agent.<br>References Bauer, D., et al.: Polym Deg. Stab., 48, 259 (1995), Nakahara, K., et al.: Chem. Physics Lett., 359, 351 (2002),<br></p>

<p>Human Hepcidin peptide hormone product also know as LEAP-1 (liver-expressed antimicrobial peptide), where the disulfides are formed by random oxidation. Hepcidin is a peptide hormone that is synthesized in the liver and is an important regulator of iron homeostasis. Through binding to ferroportin Hepcidin prevents the exportation of iron thus reducing the amount of circulating iron. Furthermore through inflammatory cytokine induction Hepcidin leads to the internalization and degradation of ferroportin thus further reducing the amount of iron in circulation. This in turn make conditions unfavourable to invading pathogens. This demonstrates Hepcidin's ability as an anti-microbial peptide. This antimicrobial behaviour can be used in research into the elimination of pathogens but also in combatting diseases where iron dysregulation is prevalant.</p>

<p>Endothelins are endothelium-derived vasoconstrictor peptides.</p>

<p>Hepcidin Protein, Larimichthys crocea, Recombinant is expressed in E.</p>

<p>Meteorin-like/METRNL Protein, Rat, Recombinant (His) is expressed in E.</p>

<p>Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile.</p>

<p>CGRP induces vasodilation.</p>

<p>Adiponectin Protein, Bovine, Recombinant (His) is expressed in yeast with N-6xHis tag.</p>

<p>Adiponectin Protein, Feline, Recombinant is expressed in E.</p>

<p>Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased</p>

<p>Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR).</p>

<p>Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His &amp; Myc) is expressed in E. coli.</p>

<p>Meteorin-like/METRNL Protein, Mouse, Recombinant (His) is expressed in E.</p>

<p>Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.</p>

<p>Endothelins are endothelium-derived vasoconstrictor peptides.</p>

<p>PTHLH Protein, Human, Recombinant (His) is expressed in E.</p>

<p>Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His) is expressed in Yeast.</p>

<p>Expression system: E. coli&lt;br&gt;Length: 71-132, Partial&lt;br&gt;Activity: Not Tested</p>