Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 178 products for "Complement System".
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C3a 70-77 2TFA(63555-63-5(free base))
C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) is an octapeptide corresponding to the COOH terminus of C3a.Formula:C39H63N13O14Purity:>99.99%Color and Shape:White SolidMolecular weight:1052.00Compstatin control peptide acetate
CAS:Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.Formula:C68H105N23O19Purity:99.96%Color and Shape:SolidMolecular weight:1548.70TLQP 21 acetate
TLQP 21 acetate: Agonist for C3aR1, EC50 - 10.3 μM (mouse), 68.8 μM (human); VGF-derived with endo/extraendocrine traits.Formula:C109H174N40O28Purity:99.99%Color and Shape:SolidMolecular weight:2492.8LEP(116-130)(mouse)TFA(258276-95-8 free base)
LEP(116-130)(mouse) is a synthetic leptin peptide fragment.Formula:C66H110F3N19O26SPurity:99.93%Color and Shape:SolidMolecular weight:1674.77Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formula:C22H15NO4S2Purity:98.49% - 98.93%Color and Shape:White SolidMolecular weight:421.49Eculizumab
CAS:Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5Purity:98.20%Color and Shape:Transparent LiquidMolecular weight:145.74 kDaADH-503
CAS:ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.Formula:C27H28N2O5S2Purity:99.03% - >99.99%Color and Shape:Yellow SolidMolecular weight:524.7Ref: TM-T7776
2mg34.00€5mg49.00€1mL*10mM (DMSO)52.00€10mg75.00€25mg120.00€50mg178.00€100mg259.00€200mg384.00€BCX 1470 methanesulfonate
CAS:BCX 1470 inhibits factor D & C1s better than trypsin (IC50: 96 nM & 1.6 nM, 3.4- & 200-fold).Formula:C15H14N2O5S3Color and Shape:SolidMolecular weight:398.48Danicopan
CAS:Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Formula:C26H23BrFN7O3Purity:99.94%Color and Shape:White SolidMolecular weight:580.41Ref: TM-T8509
1mg90.00€2mg129.00€5mg203.00€1mL*10mM (DMSO)260.00€10mg310.00€25mg527.00€50mg755.00€100mg1,044.00€Complement factor D-IN-2
CAS:Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.Formula:C27H24BrN7O3Purity:99.53%Color and Shape:SolidMolecular weight:574.43Ref: TM-T38332
1mg105.00€5mg241.00€1mL*10mM (DMSO)299.00€10mg360.00€25mg637.00€50mg900.00€100mg1,170.00€200mg1,584.00€JR14a
CAS:JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.Formula:C25H26Cl2N4O3SPurity:99.76% - 99.96%Color and Shape:SolidMolecular weight:533.47Compstatin
CAS:Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.Formula:C66H99N23O17S2Purity:>99.99%Color and Shape:SolidMolecular weight:1550.77Iptacopan hydrochloride
CAS:Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Formula:C25H31ClN2O4Purity:98.89% - 99.89%Color and Shape:Gray SolidMolecular weight:458.98Ref: TM-T9189
1mg54.00€2mg77.00€5mg114.00€1mL*10mM (DMSO)114.00€10mg185.00€25mg334.00€50mg558.00€100mg928.00€200mg1,251.00€PMX 53 acetate(219639-75-5 free base)
CAS:PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50Formula:C49H69N11O9Purity:99.91%Color and Shape:White SolidMolecular weight:956.16Ref: TM-TP2334
1mg105.00€5mg233.00€10mg344.00€1mL*10mM (DMSO)359.00€25mg532.00€50mg735.00€100mg982.00€200mg1,333.00€Complement C5a Protein, Human, Recombinant
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E.Purity:SDS-PAGE: 94.9%; SEC-HPLC: 93.5%Color and Shape:White Lyophilized PowderMolecular weight:8.3 kDa (predicted); 8.3 kDa (reducing conditions)AMY-101 acetate
AMY-101 acetate (Cp40 acetate) is a peptide, an inhibitor of C3 Complement in gingivitis and periodontitis, reduces inflammation and lowers MMP-8 and MMP-9.Formula:C85H121N23O20S2Purity:98.80% - 99.98%Color and Shape:SolidMolecular weight:1849.14C1QA Protein, Mouse, Recombinant (E. coli, His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Purity:98% - > 85% as determined by SDS-PAGEColor and Shape:Lyophilized PowderMolecular weight:29.1 kDa (predicted)Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Color and Shape:Lyophilized PowderMolecular weight:87.0 kDa (predicted)Ref: TM-TMPH-02607
5µg106.00€10µg171.00€20µg276.00€50µg418.00€100µg566.00€200µg875.00€500µg1,554.00€1mg2,350.00€Complement C8a Protein, Human, Recombinant (His)
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli.Color and Shape:Lyophilized PowderMolecular weight:65.8 kDa (predicted)Ref: TM-TMPH-01132
5µg93.00€10µg133.00€20µg213.00€50µg323.00€100µg442.00€200µg680.00€500µg1,198.00€1mg1,873.00€Complement C8b Protein, Human, Recombinant (His)
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane ofColor and Shape:Lyophilized PowderMolecular weight:67.0 kDa (predicted)Ref: TM-TMPH-01133
5µg120.00€10µg195.00€20µg324.00€50µg489.00€100µg670.00€200µg964.00€500µg1,558.00€1mg2,277.00€C1QL3 Protein, Mouse, Recombinant (His & Myc)
May regulate the number of excitatory synapses that are formed on hippocampus neurons.Color and Shape:Lyophilized PowderMolecular weight:28.6 kDa (predicted)Complement C4-B Protein, Human, Recombinant (His & SUMO)
Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.Color and Shape:Lyophilized PowderMolecular weight:49.1 kDa (predicted)Ref: TM-TMPH-01131
5µg78.00€10µg111.00€20µg178.00€50µg268.00€100µg384.00€200µg592.00€500µg1,054.00€1mg1,648.00€C1QL1 Protein, Mouse, Recombinant (His)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Color and Shape:Lyophilized PowderMolecular weight:26.9 kDa (predicted)C5AR1 Protein, Human, Recombinant (Cell-Free, His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Purity:90%Color and Shape:Lyophilized PowderMolecular weight:40.7 kDa (predicted)Complement C4-B Protein, Mouse, Recombinant (His)
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway.Color and Shape:Lyophilized PowderMolecular weight:39.0 kDa (predicted)Ref: TM-TMPH-02605
5µg98.00€10µg158.00€20µg255.00€50µg385.00€100µg532.00€200µg822.00€500µg1,459.00€1mg2,277.00€Complement C8g Protein, Human, Recombinant (His)
C8 is a constituent of the membrane attack complex.Purity:95%Color and Shape:Lyophilized PowderMolecular weight:26.4 kDa (predicted)Ref: TM-TMPH-01134
5µg78.00€10µg111.00€20µg178.00€50µg268.00€100µg384.00€200µg592.00€500µg1,054.00€1mg1,648.00€Complement factor D Protein, Rat, Recombinant (His)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternateColor and Shape:Lyophilized PowderMolecular weight:27.8 kDa (predicted)Ref: TM-TMPH-03272
5µg114.00€10µg178.00€20µg305.00€50µg447.00€100µg627.00€200µg964.00€500µg1,701.00€1mg2,673.00€C1RA Protein, Mouse, Recombinant (His & Myc)
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.Color and Shape:Lyophilized PowderMolecular weight:85.7 kDa (predicted)Ref: TM-TMPH-02602
5µg98.00€10µg158.00€20µg255.00€50µg385.00€100µg532.00€200µg822.00€500µg1,459.00€1mg2,277.00€Complement C3 Protein, Mouse, Recombinant (His & SUMO)
Complement C3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:55.3 kDa (predicted)Ref: TM-TMPH-02604
5µg98.00€10µg158.00€20µg255.00€50µg385.00€100µg532.00€200µg822.00€500µg1,459.00€1mg2,277.00€CR1 Protein, Human, Recombinant
Activity: Not Tested
Expression system: E. coli
Length: 41-234, PartialColor and Shape:Lyophilized PowderMolecular weight:21.6 kDa (Predicted)Ref: TM-TMPH-03875
5µg123.00€10µg195.00€20µg325.00€50µg410.00€100µg489.00€200µg702.00€500µg1,134.00€1mg1,648.00€Properdin Protein, Mouse, Recombinant (His & Myc)
A positive regulator of the alternate pathway of complement.Color and Shape:Lyophilized PowderMolecular weight:53 kDa (predicted)Ref: TM-TMPH-02845
5µg197.00€10µg329.00€20µg552.00€50µg1,044.00€100µg1,701.00€200µg2,673.00€500µg5,113.00€C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
Activity: Not Tested
Expression system: E. coli
Length: 306-351, PartialColor and Shape:Lyophilized PowderMolecular weight:52.8 kDa (Predicted)Ref: TM-TMPH-04213
5µg132.00€10µg212.00€20µg353.00€50µg444.00€100µg530.00€200µg762.00€500µg1,234.00€1mg1,783.00€C5AR1 Protein, Mouse, Recombinant (His & KSI)
Activity: Not Tested
Expression system: E. coli
Length: 306-351, PartialColor and Shape:Lyophilized PowderMolecular weight:20.4 kDa (Predicted)Ref: TM-TMPH-04212
5µg93.00€10µg133.00€20µg213.00€50µg305.00€100µg401.00€200µg620.00€500µg1,108.00€1mg1,728.00€Properdin Protein, Mouse, Recombinant (His)
A positive regulator of the alternate pathway of complement.Color and Shape:Lyophilized PowderMolecular weight:51.9 kDa (predicted)Ref: TM-TMPH-02844
5µg98.00€10µg158.00€20µg255.00€50µg385.00€100µg532.00€200µg822.00€500µg1,459.00€1mg2,277.00€Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:14.0 kDa (predicted)Ref: TM-TMPH-03270
5µg120.00€10µg195.00€20µg324.00€50µg489.00€100µg670.00€200µg964.00€500µg1,558.00€1mg2,277.00€Complement factor I Protein, Rat, Recombinant (His & Myc)
Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.Color and Shape:Lyophilized PowderMolecular weight:69.2 kDa (predicted)Ref: TM-TMPH-03273
5µg164.00€10µg264.00€20µg442.00€50µg833.00€100µg1,350.00€200µg1,575.00€500µg1,935.00€C1SB Protein, Mouse, Recombinant (His & Myc)
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.Color and Shape:Lyophilized PowderMolecular weight:82.4 kDa (predicted)Ref: TM-TMPH-02603
5µg120.00€10µg195.00€20µg324.00€50µg489.00€100µg670.00€200µg964.00€500µg1,558.00€1mg2,277.00€Complement C3 Protein, Bovine, Recombinant (His & SUMO)
Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:39.5 kDa (predicted)Ref: TM-TMPH-00231
5µg120.00€10µg195.00€20µg324.00€50µg489.00€100µg670.00€200µg964.00€500µg1,558.00€1mg2,277.00€Complement C5a Protein, Pig, Recombinant (His)
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process.Color and Shape:Lyophilized PowderMolecular weight:10.6 kDa (predicted)Ref: TM-TMPH-03107
5µg133.00€10µg215.00€20µg358.00€50µg537.00€100µg760.00€200µg1,071.00€500µg1,755.00€Complement factor D Protein, Rat, Recombinant (His & Myc)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternateColor and Shape:Lyophilized PowderMolecular weight:29.8 kDa (predicted)Ref: TM-TMPH-03271
5µg52.00€10µg82.00€20µg118.00€50µg202.00€100µg315.00€200µg570.00€500µg1,251.00€1mg2,295.00€C1QA Protein, Human, Recombinant (His & Myc)
C1QA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.Color and Shape:Lyophilized PowderMolecular weight:30.7 kDa (predicted)Ref: TM-TMPH-01128
5µg78.00€10µg111.00€20µg178.00€50µg268.00€100µg384.00€200µg592.00€500µg1,054.00€1mg1,648.00€C5AR1 Protein-VLP, Human, Recombinant (His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Color and Shape:Lyophilized PowderMolecular weight:41.1 kDa (predicted)Ref: TM-TMPH-01022
5µg248.00€10µg414.00€20µg698.00€50µg1,144.00€100µg1,684.00€200µg2,835.00€500µg5,653.00€C1QA Protein, Mouse, Recombinant (His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Purity:90% - 92%Color and Shape:Lyophilized PowderMolecular weight:25.6 kDa (predicted)Anti-Mouse CD11b Antibody (M1/70)
Anti-Mouse CD11b Antibody (M1/70) inhibits cell adhesion, kills cancer cells and alleviates fibrosis and inflammation.Purity:95% - 95%Color and Shape:Transparent LiquidMolecular weight:150 kDaEmpasiprubart
CAS:Empasiprubart (anti-C2 mAb) inhibits classical & lectin complement pathways upstream of C3, showing efficacy in autoimmune models.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaMBL2 Protein, Human, Recombinant (His)
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.Purity:> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Color and Shape:Lyophilized PowderMolecular weight:31 KDa (reducing condition)Ref: TM-TMPJ-00136
5µg63.00€10µg90.00€20µg138.00€50µg245.00€100µg437.00€200µg782.00€500µg1,710.00€1mg2,457.00€Avacincaptad pegol sodium
CAS:Avacincaptad pegol (ARC1905) is an anti-C5 aptamer for AMD study, inhibiting C5 cleavage.Color and Shape:SolidMolecular weight:53500Riliprubart
CAS:Riliprubart (SAR445088) is a humanised monoclonal antibody targeting C1s, applicable for neurological disorders such as CIDP, which inhibits activated C1s in the classical complement pathway.Purity:95% - 98.0% (SDS-PAGE); 99.0% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.52 kDaCrovalimab
CAS:Crovalimab (SKY59; RO7112689) is an humanised monoclonal antibody that binds to complement C5 , paroxysmal nocturnal haemoglobinuria (PNH).Purity:95%Color and Shape:Transparent LiquidMolecular weight:~150 kDaRovelizumab
CAS:Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Purity:95% - 95%Color and Shape:Transparent Liquid
