Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 191 products for "Complement System".
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L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Formula:C38H64N8O13Color and Shape:SolidMolecular weight:840.973C3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Formula:C37H62F3N13O12Purity:99.92%Color and Shape:White SolidMolecular weight:937.96Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formula:C128H190N24O33Color and Shape:SolidMolecular weight:2593.02PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formula:C47H65N11O7Purity:98%Color and Shape:SolidMolecular weight:896.09PIC1 PA
CAS:PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Formula:C71H123N19O21S2Color and Shape:SolidMolecular weight:1642.98TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formula:C107H170N40O26Purity:98%Color and Shape:SolidMolecular weight:2432.75AMY-101 TFA
CAS:AMY-101 TFA is an inhibitor of complement C3 and an immunomodulator, gingivitis and periodontitis. reduces inflammation and lowers levels of MMP-8 and MMP-9Formula:C85H118F3N23O20S2Purity:98.79% - 99.99%Color and Shape:SolidMolecular weight:1903.11Izastobart
CAS:Izastobart is an antagonistic monoclonal antibody targeting complement component 5a receptor 1 (C5aR1/CD88). Izastobart binds the N-terminus of C5aR1 and blocks the interaction between C5a and C5aR1, inhibiting receptor-mediated cell activation and migration. Izastobart is used for research on C5aR1-mediated complement signaling, immune regulation, and the tumor immune microenvironment.Purity:95%Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Formula:(C2H4O)nC170H248N50O47S4·xC2H4O2Purity:97.10%Color and Shape:Odour SolidMolecular weight:1501.7Complement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFormula:C22H20F2N6OPurity:97.77% - >99.99%Color and Shape:Yellow SolidMolecular weight:422.43Complement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Color and Shape:Lyophilized PowderMolecular weight:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Color and Shape:Lyophilized PowderMolecular weight:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.MASP2 Protein, Human, Recombinant (His)
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.Color and Shape:Lyophilized PowderMolecular weight:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.Complement C3a Protein, Mouse, Recombinant
Complement C3a Protein, Mouse, Recombinant is expressed in E.Purity:Greater than 95% as determined by reducing SDS-PAGE - Greater than 95% as determined by reducing SDS-PAGE. (QC verified)Color and Shape:Lyophilized PowderMolecular weight:9 KDa (reducing condition)Complement Factor MASP3 Protein, Human, Recombinant (His)
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.Color and Shape:Lyophilized PowderMolecular weight:31.10 kDa (predicted); 43-53 kDa (due to glycosylation)Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Color and Shape:Lyophilized PowderMolecular weight:25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.C1QBP Protein, Mouse, Recombinant (His)
C1QBP Protein, Mouse, Recombinant (His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:24.7 kDa (predicted); 32 kDa (reducing conditions)MASP2 Protein, Rat, Recombinant (E. coli, His)
MASP2 Protein, Rat, Recombinant (E.Purity:> 95% as determined by Tris-Bis PAGE - > 95% as determined by Tris-Bis PAGEColor and Shape:Lyophilized PowderMolecular weight:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.C1s Protein, Human, Recombinant (His)
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.Color and Shape:Lyophilized PowderMolecular weight:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)
Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His) is expressed in HEK293 Cells. The accession number is P01027-1.Color and Shape:Lyophilized PowderMolecular weight:187.86 kDa (Predicted); 65-68 kDa, 110-115 kDa and 165-180 kDa (Due to glycosylation)
