Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 191 products for "Complement System".
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Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formula:C128H190N24O33Color and Shape:SolidMolecular weight:2593.02C3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Formula:C37H62F3N13O12Purity:99.92%Color and Shape:White SolidMolecular weight:937.96C5a Anaphylatoxin (human)
CAS:C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFormula:C350H578N108O107S8Purity:98%Color and Shape:SolidMolecular weight:8267.51Factor B-IN-5
CAS:Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.Formula:C27H32N2O4Purity:99.71%Color and Shape:White SolidMolecular weight:448.55PMX 205
CAS:PMX 205 is an effective complement antagonist of the C5a receptor.Formula:C45H62N10O6Purity:98%Color and Shape:SolidMolecular weight:839.04ATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Formula:C42H62F3N11O11Purity:98%Color and Shape:SolidMolecular weight:954PIC1 PA
CAS:PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Formula:C71H123N19O21S2Color and Shape:SolidMolecular weight:1642.98Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Formula:(C2H4O)nC170H248N50O47S4·xC2H4O2Purity:97.10%Color and Shape:Odour SolidMolecular weight:1501.7tLyP-1 peptide
CAS:tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Formula:C31H59N15O10SColor and Shape:SolidMolecular weight:833.96Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formula:C68H100F3N23O19S2Color and Shape:SolidMolecular weight:1664.79C5a Receptor agonist, mouse, human
CAS:C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as anFormula:C44H72N10O7Purity:98%Color and Shape:SolidMolecular weight:853.11ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Color and Shape:SolidMolecular weight:120702.76Omoprubart
CAS:Omoprubart is an anti-C5 humanized monoclonal antibody blocking C5 cleavage and MAC formation (EC50 = 3.473 ng/mL) for PNH and complement research.Molecular weight:~148 kDaJPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formula:C49H63FN10O9Color and Shape:SolidMolecular weight:955.0845PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formula:C71H123N19O21S2·xC2HF3O2Color and Shape:SolidFactor B-IN-1
CAS:Factor B-IN-1 is a Factor B inhibitor.Formula:C19H16N4O2Color and Shape:SolidMolecular weight:332.3559Certepetide
CAS:Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.Formula:C37H60N14O14S2Color and Shape:SolidMolecular weight:989.088PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formula:C47H65N11O7Purity:98%Color and Shape:SolidMolecular weight:896.09TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formula:C107H170N40O26Purity:98%Color and Shape:SolidMolecular weight:2432.75BM213
CAS:BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Formula:C43H70N12O10Purity:98%Color and Shape:SolidMolecular weight:915.0903
