Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 180 products for "Complement System".
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C1QL3 Protein, Mouse, Recombinant (His & Myc)
May regulate the number of excitatory synapses that are formed on hippocampus neurons.Color and Shape:Lyophilized PowderMolecular weight:28.6 kDa (predicted)Avacincaptad pegol sodium
CAS:Avacincaptad pegol (ARC1905) is an anti-C5 aptamer for AMD study, inhibiting C5 cleavage.Color and Shape:SolidMolecular weight:53500Gefurulimab
CAS:Gefurulimab (ALXN-1720) is a bispecific antibody derived from humans, targeting complement C5 and albumin.Color and Shape:LiquidRovelizumab
CAS:Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Purity:95% - 95%Color and Shape:Transparent LiquidEmpasiprubart
CAS:Empasiprubart (anti-C2 mAb) inhibits classical & lectin complement pathways upstream of C3, showing efficacy in autoimmune models.Purity:95%Color and Shape:LiquidMolecular weight:~150 kDaCrovalimab
CAS:Crovalimab (SKY59; RO7112689) is an humanised monoclonal antibody that binds to complement C5 , paroxysmal nocturnal haemoglobinuria (PNH).Purity:95%Color and Shape:Transparent LiquidMolecular weight:~150 kDaAnti-Mouse CD11b Antibody (M1/70)
Anti-Mouse CD11b Antibody (M1/70) inhibits cell adhesion, kills cancer cells and alleviates fibrosis and inflammation.Purity:95% - 98.1% (SDS-PAGE); 99.8% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:147.31 kDaTanruprubart
CAS:Tanruprubart, Humanized anti-C1q mAb, classical complement pathway target, prevents neuroinflammation, for Guillain-Barré syndrome (GBS) studies.Purity:95% - 95%Color and Shape:Transparent LiquidRiliprubart
CAS:Riliprubart (SAR445088) is a humanised monoclonal antibody targeting C1s, applicable for neurological disorders such as CIDP, which inhibits activated C1s in the classical complement pathway.Purity:95% - 98.0% (SDS-PAGE); 99.0% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.52 kDaComplement C8 γ Protein, Human, Recombinant (His)
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.Color and Shape:Lyophilized PowderMolecular weight:22 KDa (reducing condition)Ref: TM-TMPJ-00585
10µg120.00€20µg178.00€50µg351.00€100µg563.00€200µg888.00€500µg1,710.00€1mg2,457.00€MBL2 Protein, Human, Recombinant (His)
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.Purity:> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Color and Shape:Lyophilized PowderMolecular weight:31 KDa (reducing condition)Anti-Mouse CD11b Antibody (5C6)
Anti-Mouse CD11b Antibody (5C6) inhibits myelomonocytic cell adhesion and inflammatory cell recruitment.Purity:95% - 97.7% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.68 kDaClaseprubart
CAS:Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.Color and Shape:LiquidGreziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidBCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Formula:C14H10N2O2S2Purity:98%Color and Shape:SolidMolecular weight:302.37Isocyclosporin A
CAS:Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Formula:C62H111N11O12Color and Shape:SolidMolecular weight:1202.61C5aR-IN-2
CAS:C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Formula:C36H40FN5O2Color and Shape:SolidMolecular weight:593.73NRP1 antagonist 2
CAS:NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Formula:C20H17ClN6OS2Color and Shape:SolidMolecular weight:456.97FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Formula:C23H23NO4Purity:98.85%Color and Shape:White SolidMolecular weight:377.43C1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formula:C16H22Cl3N5Color and Shape:SolidMolecular weight:390.74
