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Complement System

Complement System

The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.

Found 156 products of "Complement System"

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  • C3a Receptor Agonist
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    C3a Receptor Agonist

    CAS:
    <p>C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.</p>
    Formula:C27H35N3O2
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:433.59

    Ref: TM-T38287

  • NDT 9513727
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    NDT 9513727

    CAS:
    <p>NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.</p>
    Formula:C36H35N3O4
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:573.68

    Ref: TM-T24524

  • Complement C5-IN-1
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    Complement C5-IN-1

    CAS:
    <p>Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).</p>
    Formula:C24H32N2O6
    Purity:98.27%
    Color and Shape:Solid
    Molecular weight:444.52

    Ref: TM-T10863

  • Factor D inhibitor 6
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    Factor D inhibitor 6

    CAS:
    <p>Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.</p>
    Formula:C23H22ClFN6O3
    Color and Shape:Solid
    Molecular weight:484.92

    Ref: TM-T38803

  • W-54011
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    W-54011

    CAS:
    <p>W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).</p>
    Formula:C30H37ClN2O2
    Purity:96.8%
    Color and Shape:Solid
    Molecular weight:493.08

    Ref: TM-T17250

  • Factor B-IN-2
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    Factor B-IN-2

    CAS:
    <p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>
    Formula:C25H32N2O4
    Color and Shape:Solid
    Molecular weight:424.53

    Ref: TM-T62292

  • EG01377
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    EG01377

    CAS:
    <p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>
    Formula:C26H30N6O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:586.68

    Ref: TM-T11154

  • C5aR-IN-1
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    C5aR-IN-1

    CAS:
    <p>C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.</p>
    Formula:C36H39F4N3O2
    Color and Shape:Solid
    Molecular weight:621.71

    Ref: TM-T73261

  • Iptacopan
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    Iptacopan

    CAS:
    <p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>
    Formula:C25H30N2O4
    Purity:99.07% - >99.99%
    Color and Shape:Solid
    Molecular weight:422.52

    Ref: TM-T11864

  • C5aR-IN-3
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    C5aR-IN-3

    CAS:
    <p>C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.</p>
    Formula:C36H40FN5O3
    Color and Shape:Solid
    Molecular weight:609.73

    Ref: TM-T73262

  • (Rel)-Factor B-IN-5
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    (Rel)-Factor B-IN-5

    CAS:
    <p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>
    Formula:C27H32N2O4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:448.55

    Ref: TM-T62689

  • Factor B-IN-3
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    Factor B-IN-3

    CAS:
    <p>Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.</p>
    Formula:C24H29N3O4
    Color and Shape:Solid
    Molecular weight:423.5

    Ref: TM-T62276

  • Pelecopan
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    Pelecopan

    CAS:
    <p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>
    Formula:C23H19FN2O4
    Color and Shape:Solid
    Molecular weight:406.41

    Ref: TM-T62020

  • Factor B-IN-4
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    Factor B-IN-4

    CAS:
    <p>Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.</p>
    Formula:C27H32N2O4
    Color and Shape:Solid
    Molecular weight:448.55

    Ref: TM-T62688

  • CymitQuimica logo
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    TLQP-21 TFA

    <p>TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.</p>
    Purity:98%
    Color and Shape:Liquid

    Ref: TM-T38077

    1mg
    Discontinued
    5mg
    Discontinued
    10mg
    Discontinued
    Discontinued product
  • CymitQuimica logo
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    TLQP-21 TFA

    <p>TLQP-21 TFA （TLQP-21 Trifluoroacetate） 是一种 VGF 衍生肽，可通过结合后折叠机制激活C3aR1 受体。</p>
    Purity:98%

    Ref: TM-T35387

    5mg
    Discontinued
    25mg
    Discontinued
    Discontinued product