Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Found 191 products for "Complement System".
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C5aR-IN-2
CAS:C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Formula:C36H40FN5O2Color and Shape:SolidMolecular weight:593.73BCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Formula:C14H10N2O2S2Purity:98%Color and Shape:SolidMolecular weight:302.37Anti-Human Complement Factor B Antibody
Anti-Complement Factor B Antibody is a potent inhibitory antibody targeting complement factor B. Anti-Complement Factor B Antibody demonstrates the capacity to suppress complement-mediated inflammatory responses and provides essential utility for researching alternative pathway-driven immune disorders.Molecular weight:145.59 kDa (Predicted)Isocyclosporin A
CAS:Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Formula:C62H111N11O12Color and Shape:SolidMolecular weight:1202.6112NRP1 antagonist 2
CAS:NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Formula:C20H17ClN6OS2Color and Shape:SolidMolecular weight:456.97FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Formula:C23H23NO4Purity:98.85%Color and Shape:White SolidMolecular weight:377.433Anti-Human CD88/C5AR1 Antibody (G2_anti-C5aR)
Anti-CD88/C5AR1 Antibody (G2_anti-C5aR) is a human monoclonal antibody (mAb) targeting C5AR1.Color and Shape:Odour LiquidASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Color and Shape:Odour LiquidC1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formula:C16H22Cl3N5Color and Shape:SolidMolecular weight:390.738MEDI7814
MEDI7814 is a humanized monoclonal antibody inhibitor targeting C5a and C5adesArg. It has binding affinities of 14 pM for recombinant human C5a and 8 pM for serum-purified human C5a. MEDI7814 shows potential for treating acute inflammatory conditions, including sepsis and renal ischemia-reperfusion injury.C3a Receptor Agonist
CAS:C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.Formula:C27H35N3O2Purity:99.76%Color and Shape:SolidMolecular weight:433.5857Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Formula:C24H32N2O6Purity:98.27%Color and Shape:White SolidMolecular weight:444.5207NDT 9513727
CAS:NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Formula:C36H35N3O4Purity:99.16%Color and Shape:SolidMolecular weight:573.68EG00229
CAS:EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.Formula:C19H20F3N7O7S3Purity:98.23%Color and Shape:SolidMolecular weight:611.595C5aR-IN-1
CAS:C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.Formula:C36H39F4N3O2Color and Shape:SolidMolecular weight:621.71Factor D inhibitor 6
CAS:Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.Formula:C23H22ClFN6O3Color and Shape:SolidMolecular weight:484.911Factor B-IN-2
CAS:Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.Formula:C25H32N2O4Color and Shape:SolidMolecular weight:424.53Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Formula:C29H28BrN7O3Color and Shape:SolidMolecular weight:602.482EG01377
CAS:EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.Formula:C26H30N6O6S2Purity:98%Color and Shape:SolidMolecular weight:586.68W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formula:C30H37ClN2O2Purity:96.8%Color and Shape:White SolidMolecular weight:493.08
