Carbohydrates and glycoconjugates

<p>Trehalose is a naturally occurring disaccharide found in many organisms.Its role in nature is as versatile as its applications in the laboratory. Trehalose is synthesized by cells in response to stress and helps retaining the cellular integrity under tough conditions: An important function of Trehalose is to stabilize protein structures and to prevent proteins from their degradation. Researchers use Trehalosefor instance as a carbon source in selective microbiological media, as desiccation protectant and for cryoprotection.</p>

<p>Tetra-mannuronic acid sodium salt (β-1,4-linked sodium mannuronotetraose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.  Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>4'-Sulfated Lewis X methyl glycoside sodium is a synthetic monosaccharide. It is used in the synthesis of oligosaccharides and polysaccharides. This compound can be fluorinated to produce 4'-fluoro-4'-sulfated Lewis X methyl glycoside sodium. The sulfate group on this compound can be replaced with other groups such as carboxyl, cyano, nitro, and acetyl.</p>

<p>2-O-(β-D-galactopyranosyl)-D-glucose is a sugar that can be custom synthesized to meet your needs. It is an oligosaccharide, polysaccharide, and carbohydrate that has been modified with methylation, glycosylation, and carbonylation. This product is available in high purity and fluorination.</p>

<p>Disialylated tetrasaccharide naturally present in human breast milk that has been identified as one of the binding sites of the C fragment of the clostridial tetanus toxin.</p>

<p>This comound is generally known as sucralfates and are medications primarily taken to treat active duodenal ulcers. They are also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers.  Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.</p>

<p>Intermediate in synthesis of ganglioside GD2</p>

<p>Competitive inhibitor of β-glucosidase from Streptomyces sp. and Paenibacillus polymyxa, occupying enzyme’s aglycone-binding site.  The compound is also a potent inducer of cellulase and other lignin-degrading enzymes in Schizophyllum commune.</p>

<p>A1 Glycan, 2-AB labelled is a custom synthesis of a complex carbohydrate. The carbohydrate is an oligosaccharide that has been modified with methylation and glycosylation. The carbohydrate has a CAS number and is a polysaccharide. It is modified with saccharide, methylation, and glycosylation. The carbohydrate has undergone click modification and fluorination and it is synthetic.</p>

<p>The conformation of the 2-[[2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-βDglucopyranosyl)-βDglucopyranosyl]oxy]ethyl]carbamic acid phenylmethyl ester molecule has been studied by X-ray crystallography. The molecule adopts a chair conformation with the two acetyl groups occupying equatorial positions. The molecule is planar with an angle of 110° between the NH and CO axes. The calculated electron diffraction pattern was in good agreement with the experimental data. The analysis yielded a set of independent amplitudes for each reflection that were analysed to give structure constants and electron distributions.</p>

<p>Neutral hexasasaccharide naturally present in human breast milk</p>

<p>Used to differentiate microorganisms based on their metabolic properties.</p>

<p>Monofucosyl (1-2)-iso-lacto-N-octaose II is an oligosaccharide that is found in human milk</p>

<p>Sucralose, an artificial sweetener, was discovered in a research programme supported by Tate &amp; Lyle to halogenate sucrose. The majority of ingested sucralose is not broken down by the body, so it is noncaloric. In the European Union, it has been given the E number E955. Sucralose is about 320 to 1,000 times sweeter than sucrose, three times as sweet as both aspartame and acesulfame potassium, and twice as sweet as sodium saccharin.  It is stable under heat and over a broad range of pH conditions. Therefore, it can be used in baking or in products that require a long shelf life. The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste profile, stability, and safety.</p>

<p>Cancer-associated carbohydrate antigen</p>

<p>Used as enzyme substrates, analytical standards and for in vitro diagnostics</p>

<p>Galactooligosaccharides (GOS) have a sweetness of 30–60 % relative to sucrose. They have applications in a wide range of food products such as sweeteners, bulking agents, and sugar substitutes and are found in a range of product types including bread, ‘sports’ drinks, jams, fermented milk, confectionary and desserts. In Europe they are incorporated into infant formula foods.</p>

<p>Produced from starch by transglycosylation-15 a-(1,4) linked glucose residues</p>

<p>Benzyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is an oligosaccharide that is synthesized from D-(+)-galactose, D-(+)-glucose and benzyl alcohol. This product can be used for the modification of saccharides and has been shown to have a high purity. It has been fluorinated at the alpha position and glycosylated with acetamidobenzoyl group. The molecular weight of this product is 378.12 g/mol. CAS No.: 53167-38-7</p>

<p>4-Methoxyphenyl 4-O-{4-O-[3,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-bDglucopyranosyl)-2,4,6-trihydroxybenzylidene]-aDmannopyra nosyl} -3,6diO(benzyl) -2deoxy2phthalimido -bDglucopyranoside is a high purity synthetic oligosaccharide. It is a complex carbohydrate with a high degree of polymerization. This product has been synthesized by Click modification and fluorination. The product contains an acetate group at the reducing end of the sugar chain and may be glycosylated. The CAS number for this product is</p>