Carbohydrates and glycoconjugates

<p>1,2-a-1,2-a-L-Rhamnotriose is a carbohydrate that can be modified to suit your needs. It has a CAS number of 57749-83-5. This oligosaccharide is a sugar made up of two monosaccharides joined by an alpha 1,2 glycosidic bond. The product can be custom synthesized and its purity is high. It can be fluorinated or methylated and it can also be glycosylated. Click modification is also possible with this product.</p>

<p>MurNAc-6-phosphate-GlcNAc is a complex carbohydrate that is composed of a glycosylation, methylation, and fluorination. It is an important component in polysaccharides and oligosaccharides. This compound has been modified with Click chemistry to form a reactive site for incorporation of a variety of molecules such as fluorophores, biotin, or other small molecules. This compound can be synthesized using custom synthesis methods and has CAS number 106579-01-4. MurNAc-6-phosphate-GlcNAc is available in high purity and can be custom synthesized to specific needs.</p>

<p>Di-N-acetyl-D-lactosamine (DNL) is a sugar that is found in the mammalian tissues and can be used as a lectin to specifically bind to glycoproteins. It has been shown to have specificities for enteritis, and can be used to detect or analyze the sequences of oligosaccharides. DNL has been immobilized on silica gel, which was then reacted with lectins, such as concanavalin A, wheat germ agglutinin, and soybean agglutinin. This process allows for the detection of high-mannose-type oligosaccharides.</p>

<p>Man-5 Glycan, 2-AB labelled is a synthetic oligosaccharide that contains a mannose and a galactose moiety. It has been synthesized by click chemistry with the use of 2-aminobenzaldehyde and glycosylation with methylated and fluorinated mannose. This compound is used as a standard for the detection of carbohydrate binding proteins.</p>

<p>2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl N-acetylserine is a synthetic glycosyl amino acid.</p>

<p>Tridecyl beta-D-maltopyranoside is a synthetic saccharide that has been modified with fluorination and methylation. The carbohydrate can be used in the synthesis of glycosylated proteins. The product is available for custom synthesis, and it is offered in high purity form.</p>

<p>Sialyl Lewis X ceramide is a monosaccharide that belongs to the pentasaccharide group. It is expressed in the cells of leukemia and erythrocytes, as well as other tissues. Sialyl Lewis X ceramide is a hybrid molecule that has a backbone consisting of four sugar molecules and an amino acid sequence, with hydroxyl groups on one end and an acetyl glucosamine on the other end. The molecule has a carbohydrate skeleton consisting of galactose, glucose, mannose, and sialic acid. Sialyl Lewis X ceramide also interacts with selectins to mediate leukocyte-endothelial interactions in inflammation.</p>

<p>Substrate for b-6-GlcNAc-transferase</p>

<p>4-Methoxyphenyl 2-acetamido-3,6-di-O-acetyl-4-O-[2,4-di-O-(3,6,9)-triacetyldi-O-(3,4,6)-triacetyldiacetamido]-bDglucopyranoside (MPPA) is a modification of the natural oligosaccharide 3,6,-di-O-(2,4-di-O-(3,6,9)-triacetyldiacyl)-bDmannopyranosyl. MPPA is synthesized by methylation and glycosylation of glucose residues in the backbone of the natural oligosaccharide. The methylated glycosidic linkages are substituted for acetamido groups in order to confer water solubility to the molecule. MPPA has been shown to be an effective inhibitor of influenza virus replication in vitro.</p>

<p>NA3 Glycan is a custom-synthesized Oligosaccharide that has been modified by the addition of 2AB labelled. This glycan contains an N-acetylglucosamine residue at its reducing end. The NA3 Glycan can be used for a wide range of applications, including glycosylation reactions, click reactions, and carbohydrate chemistry. It is also available in high purity and with fluorination on the sugar moiety.</p>

<p>This is a synthetic, fluorinated, monosaccharide. It has been custom synthesized and is available in high purity. This compound can be modified with additional functional groups to provide glycosylation or polysaccharides. The CAS number for this product is 538-37-0.</p>

<p>Useful CO2-philic compounds with potential uses as pharmaceutical excipients, controlled release agents, and surfactants for microemulsion systems in CO2-based processes.</p>

<p>GD2 oligosaccharide is the core trisaccharide structure of the ganglioside GD2 (sodium salt) (GalNAcβ1,4Galβ1,4Glc) with its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>This is a custom synthesis of a complex carbohydrate. The modification, fluorination, methylation, and monosaccharide composition of this carbohydrate have been modified by the Click modification technique. This carbohydrate has the CAS No. 59057-77-4 and a molecular weight of 1,914. It is an oligosaccharide saccharide with glycosylation and sugar composition that are classified as carbohydrates.</p>

<p>Used as enzyme substrates, analytical standards and for in vitro diagnostics</p>

<p>Fructooligosaccharide is a natural carbohydrate that is used in dietary supplements and as an additive to food products. It is a prebiotic, meaning it stimulates the growth of beneficial bacteria in the colon. Fructooligosaccharide has been shown to be effective against bowel disease by up-regulating protein genes and enzyme activities. Fructooligosaccharide also has significant anti-inflammatory properties. The anti-inflammatory effects may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Tri-mannuronic acid sodium salt (b-1,4-linked sodium mannuronotriose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>6-Amino-6-deoxy-D-lactose is a high purity, custom synthesis sugar that has been fluorinated and glycosylated. It can be used in the synthesis of oligosaccharides, monosaccharides, saccharides or complex carbohydrates. 6-Amino-6-deoxy-D-lactose can be found under CAS No. 5892-84-7.</p>

<p>3,4-Di-O-acetyl-2,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-a-D mannopyranose is a modification of the carbohydrate oligosaccharide. It is a custom synthesis that has high purity and CAS number. The structure of the molecule is an Oligosaccharide with a Carbohydrate. This molecule is an example of a complex carbohydrate. The monosaccharide in this compound is glucose and it has been methylated and glycosylated. This molecule also has a polysaccharide sugar which can be fluorinated or saccharided.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-cellobiosyl bromide is a naturally occurring trisubstituted steroidal glycoside. It is insoluble in water and activated by chloride ions. 2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-cellobiosyl bromide has been shown to have antiviral properties in mammalian tissue cultures. This compound also has potential use as an ingredient in skin care products due to its ability to inhibit the production of fatty acids that are essential for the replication of viruses.<br>2,3,6,2',3',4',6'-Hepta-O-acetyl-a-D-cellobiosyl bromide can be found in microalgae and food composition as a nutrient.</p>