Carbohydrates and glycoconjugates

<p>Rhodionin is a natural product that has been shown to be effective as a food preservative. It is produced through the extraction of usnic acid from Rhodiola rosea and has been used in the study of amyloid protein. Rhodionin is an extractant that has been shown to be able to control analysis of sodium citrate in food composition. The use of rhodionin for this purpose was found to be practical and effective, with no significant changes in the quality or quantity of citric acid. This extractant also shows promise as an analytical method for the detection of ganoderma lucidum, human liver cancer cells, and flavonol glycosides.</p>

<p>Galacto-N-biose-PAA-biotin is a carbohydrate that is synthesized by the addition of PAA (polyallylamine) to galactose. This compound can be used in fluorescence labeling and detection of carbohydrates, glycosylation, and polysaccharide synthesis. Galacto-N-biose-PAA-biotin has a CAS number (CAS: 146988-01-4).</p>

<p>Disialyloctasaccharide is a sialylated glycan that is found in human serum. It is a diagnostic marker for cancer, and has been shown to be elevated in women with breast cancer. Disialyloctasaccharide can also be used as a biomarker for depression. The amino acid sequence of this glycan has been determined, and it has been shown that the protein glycosylation of disialyloctasaccharide is quantified by measuring the relative amount of sialic acid residues in the molecule. Disialyloctasaccharide can be used as a biomarker for eukaryotes, including yeast and mammals. This glycan also has anti-tumor activity, which may be due to its ability to bind to receptors on tumor cells.</p>

<p>N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside is a galactosyltransferase inhibitor. It prevents the enzymatic transfer of a sugar group from UDP-galactose to an acceptor molecule by binding to the enzyme. N,N'-Diacetyl-3,6,3',4',6'-penta-O-acetyl-1-chlorochitobioside inhibits the enzymatic galactosylation of glycoproteins in cells and has been shown to be effective against bacterial strains resistant to other antibiotics. This drug is also chemoenzymatically synthesized using enzymes and chemical reagents.</p>

<p>This product is a fatty acid that binds to the carbohydrate binding sites in the cell membrane of Caco-2 cells. It has been shown to inhibit the growth of cancer cells and radiation induced changes by binding to the sugar moieties on glycoproteins. This product also inhibits the production of glycoconjugates, which are important for cell-cell interactions and biological function. The disaccharide form has been found to be a diagnostic agent for cancer cells, with a structural formula that can be seen in the figure below.</p>

<p>2-Acetamido-4-O-(2-acetamido-3,6-di-O-acetyl-2,4-dideoxy-b-D-glucopyranosyl)-1,3,6-tri-O-benzyl-2-deoxy -bDglucopyranoside is a methylated oligosaccharide. It can be synthesized by the click reaction of 2,4,6--trichlorobenzaldehyde with 3,6--diacetyl--2,4--dideoxy--bDglucopyranose. This compound has an acetamido group on C3 and a benzoyl group on C6. The molecular weight of this compound is 1076 g/mol.</p>

<p>O-[2-Acetamido-4,6-O-benzylidene-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-a-D-galactopyranosyl]-N -Fmoc--L--threonine allyl ester is a carbohydrate that can be custom synthesized. It is an Oligosaccharide with the following structure: The chemical formula is C36H60NO22 and the molecular weight is 752.8 g/mol. It has a CAS number of 384346–85–4 and it's Chemical Abstract Service (CAS) name is O-[2-(acetamido)-4,6-[O-(2,3,4,6 tetra‑O‑acetyl‑β‑D‑galactopyranosyl)‑α‑</p>

<p>Hexasaccharide dp6 is a synthetic hexasaccharide that mimics heparin. It binds to the antithrombin III and pentasaccharide in human plasma, which are proteins that inhibit blood clotting. Hexasaccharide dp6 also has affinity for peptides from HIV-1 and anti-HIV activity. Hexasaccharide dp6 can be used to prevent coagulation or as an antithrombotic agent.</p>

<p>Xyloglucan octasaccharide is a carbohydrate with eight monosaccharide units. The molecule has been shown to be capable of scavenging active oxygen, which is a reactive oxygen species that can lead to tissue damage. Xyloglucan octasaccharide has also been shown to stimulate the germination rate of wheat seeds.</p>

<p>Sialyl-Lea-APD-HSA is a methylated, saccharide polysaccharide that has been modified with Click chemistry. It is a complex carbohydrate that has been synthesized by glycosylation and fluorination. The CAS number for this product is 123456-78-9. This product can be custom synthesized to order in high purity and with high quality.</p>

<p>The core trisaccharide of the ganglioside GD2,protected with a propargyl glycoside group, is the most prominent alkynyl glycoside used in oligosaccharide synthesis (Das, 2016). The structure (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>A3 N-Glycan is a glycosylation profile marker that is specific for the cancer cells. It discriminates between healthy and cancerous cells, which has been shown by analyzing the A3 N-glycan profiles in human plasma samples. The A3 N-glycan marker is detected using high performance liquid chromatography (HPL) analysis. This assay can be used to diagnose cancer and monitor its progression.</p>

<p>Methyl 2-O-allyl-4,6-O-benzylidene-3-O-(2',3',4',6'-tetra-O-acetyl-a-D-mannopyranosyl)-a-D-mannopyranoside is a sugar that is synthesized by the methylation of an oligosaccharide. This product is a white crystalline powder that has been shown to have high purity and a CAS number of 82185-93-1. It has also been modified with fluorination, which makes it resistant to degradation. Methyl 2-O-allyl 4,6 O benzylidene 3 O (2',3',4',6'-tetra - O acetyl - a D mannopyranosyl) - a D mannopyranoside is used in the synthesis of complex carbohydrates.</p>

<p>Sialyl-Lex-hexa-APD-HSA is a high purity synthetic glycosylation that is custom synthesized. It has been modified with fluorination, methylation, and click modification. Sialyl-Lex-hexa-APD-HSA can be used in the synthesis of complex carbohydrates and is available in CAS Number: 75869-57-3.</p>

<p>This is a custom synthesis of a polysaccharide.</p>

<p>a-Tetrasaccharide-APE-KLH is a modification of the original tetrasaccharide APE-KLH conjugate. This modified conjugate has increased stability and higher binding affinity to the Fc receptor, which is required for antibody therapy. It is synthesized by custom synthesis and has high purity, with a CAS number of 674797-36-5. The monosaccharides in this conjugate are methylated and glycosylated, with a molecular weight of 1254. The saccharides are fluorinated and saccharide with a molecular weight of 1354.</p>

<p>Man-3-F N-Glycan is a custom synthesis of an oligosaccharide. It is a polysaccharide that is modified with methylation, glycosylation and click modification. Man-3-F N-Glycan is a high purity product that has been fluorinated for use in synthetic biology.</p>

<p>Lewis A trisaccharide methyl glycoside tetrabenzylether is a synthetic glycosylated oligosaccharide. It is a custom synthesis product that can be modified to the customer's specifications. The modification reaction yields a high-purity, complex carbohydrate with a saccharide content of 95%. This product is soluble in DMSO and DMF and is stable at pH 3-11.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-b-D-maltosyl isothiocyanate is a custom synthesis of a complex carbohydrate. It has been modified by fluorination and click chemistry. The product is available in high purity with CAS No. 81319-58-6. This product is synthesized from a monosaccharide and polysaccharide. The product is produced by methylation of the complex carbohydrate followed by modification with fluoro groups to create the desired product.</p>

<p>3-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactose is a synthetic compound that is synthesized by the reaction of 3,4,6-trihydroxypyranose with trifluoroacetic anhydride. The product can be purified to the desired level of purity using preparative HPLC or recrystallization. The CAS number for this compound is 97096-73-6.END&gt;</p>