Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Found 2393 products of "Ketones and derivatives"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
5′-Acetyl-2′-fluoro-3-methyl-[1,1′-biphenyl]-4-carbaldehyde
CAS:Purity:≥95%Molecular weight:256.2760014′-Chloro-3′-(trifluoromethoxy)acetophenone
CAS:Formula:C9H6ClF3O2Color and Shape:SolidMolecular weight:238.593′,4′-Difluoropropiophenone
CAS:Formula:C9H8F2OPurity:97%Color and Shape:LiquidMolecular weight:170.1591,1′-(2-Hydroxy-5-methyl-1,3-phenylene)diethanone
CAS:Formula:C11H12O3Purity:95.0%Molecular weight:192.2144-Chloro-3-(trifluoromethyl)acetophenone
CAS:Formula:C9H6ClF3OPurity:98%Color and Shape:SolidMolecular weight:222.59(S)-(+)-Ibuprofen Propylene Glycol Ester
CAS:Controlled ProductFormula:C16H24O3Color and Shape:NeatMolecular weight:264.362,2-Dimethoxy-2-phenylacetophenone
CAS:<p>Applications 2,2-Dimethoxy-2-phenylacetophenone (cas# 24650-42-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C16H16O3Color and Shape:White PowderMolecular weight:256.301-(3,4-Dimethylphenyl)ethanol
CAS:Controlled Product<p>Applications 1-(3,4-Dimethylphenyl)ethanol is an intermediate in the production of Medetomidine (M203250), α2-Adrenergic agonist. Sedative; analgesic.<br>References Kagechika, H., et al.: J. Med. Chem., 32, 1098 (1989), ; Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987),<br></p>Formula:C10H14OColor and Shape:NeatMolecular weight:150.22rac-2’,4’-Dimethyl Ketoprofen
CAS:Controlled Product<p>Applications rac-2’,4’-Dimethyl Ketoprofen is an impurity of Ketoprofen (K200800), an anti-inflammatory and analgesic agent.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Formula:C18H18O3Color and Shape:NeatMolecular weight:282.333-(Cyanomethyl)benzoic Acid
CAS:Controlled Product<p>Impurity Ketoprofen EP Impurity H<br>Applications 3-(Cyanomethyl)benzoic Acid (Ketoprofen EP Impurity H) is a reagent used in the synthesis of various pharmaceutically important compounds, such as its use in the synthesis of neprilysin inhibitors.<br>References Solomon, S.D., et al.: Lancet., 380 1387 (2012); Dadd, M.R., et al.: Enzyme. Microb. Tehcnol., 29, 20 (2001);<br></p>Formula:C9H7NO2Color and Shape:NeatMolecular weight:161.16R-(-)-Norapomorphine Hydrochloride
CAS:Controlled Product<p>Applications An Apomorphine derivative as inhibitor of amyloid-β (Aβ) fibril formation and their use in amyloidosis based disease.<br>References Howlett, D., et al.: Biochem. J., 340, 283 (1999), Kuner, P., et al.: J. Biol. Chem., 275, 1673 (2000), Ono, K., et al.: J. Neurosci. Res., 75, 742 (2004),<br></p>Formula:C16H15NO2•HClPurity:>90%Color and Shape:NeatMolecular weight:253.3036463-(6-Methoxy-2-naphthalenyl)-5-methylcyclohexanone (Impurity)
CAS:Formula:C18H20O2Color and Shape:NeatMolecular weight:268.35N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N-methylnitrous amide
CAS:Controlled ProductFormula:C12H14N4O2Color and Shape:NeatMolecular weight:246.27(-)-N-Desmethyl Tramadol
CAS:Controlled Product<p>Applications An optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formula:C15H23NO2Color and Shape:NeatMolecular weight:249.3516,17-Dehydro Capsaicin
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications A dehydrogenated metabolite of Capsaicin (C175680).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glinsukon, T., et al.: Toxicon, 18, 215 (1980), Obach, R., et al.: Drug Metab. Dispos., 29, 1599 (2001), Reilly, C., et al.: Toxicol. Sci., 73, 170 (2003),<br></p>Formula:C18H25NO3Color and Shape:Off-White To BrownMolecular weight:303.43-Methoxy Acetaminophen-d3
CAS:Controlled Product<p>Applications 3-Methoxy Acetaminophen-d3 is deuterium labeled 3-Methoxy Acetaminophen (M226050). 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C92H3H8NO3Color and Shape:NeatMolecular weight:184.207Ketoprofen-13CD3 Methyl Ester
CAS:Controlled Product<p>Applications An intermediate for the synthesis of Labelled Ketoprofen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Derewenda, Z., et al.: J. Mol. Biol., 227, 818 (1992), Grochulski, P., et al.: J. Biol. Chem., 268, 12843 (1993).<br></p>Formula:C1613CH13D3O3Color and Shape:NeatMolecular weight:272.324'-Isobutyl-2,2-dibromopropiophenone
CAS:Controlled Product<p>Applications Intermediate in the synthesis of Ibuprofen.<br></p>Formula:C13H16Br2OColor and Shape:NeatMolecular weight:348.07Trimebutine EP Impurity E-Nitroso
Controlled ProductFormula:C21H26N2O6Color and Shape:NeatMolecular weight:402.4411-(2,5-Dimethylphenyl)ethanol
CAS:Controlled Product<p>Applications 1-(2,5-Dimethylphenyl)ethanol can be used as a reagent in reactions or as a aroma compound<br>References Zhou, J., et al.: Yuanyi Xuebao., 37, 1621-1628 (2010)<br></p>Formula:C10H14OColor and Shape:NeatMolecular weight:150.22Trimebutine-d9 Maleate Salt
CAS:Controlled Product<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C22H20D9NO5·C4H4O4Color and Shape:NeatMolecular weight:512.6D 13223-d4 (Flupirtine Metabolite)
CAS:Controlled Product<p>Applications The major active labelled metabolite of Flupirtine in human plasma. A potassium channel opener<br>References Niebch, G., et al.: Arzneim.-Forsch., 42, 1343 (1992), Friedel, H., et al.: Drugs, 45, 548 (1993), Fu, I., et al.: J. Pharm. Biomed. Anal., 18, 347 (1998),<br></p>Formula:C14H12D4ClFN4OColor and Shape:NeatMolecular weight:314.78(S)-(+)-Ibuprofen 2-(Benzyloxy)propan-1-yl Ester
Controlled Product<p>Applications (S)-(+)-Ibuprofen 2-(Benzyloxy)propan-1-yl Ester is an intermediate in the synthesis of (S)-(+)-Ibuprofen Propylene Glycol Ester (I140100), a derivative of (S)-(+)-Ibuprofen (I140010), a nonsteroidal anti-inflammatory drug (NSAID).<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C23H30O3Color and Shape:NeatMolecular weight:354.4836,6'-Dimethoxy-2,2'-binaphthalene
CAS:Controlled Product<p>Applications 6,6'-Dimethoxy-2,2'-binaphthalene, can be used for the synthesis of novel classes of non-steroidal substrate mimetics, as inhibitors of human CYP17. It is also an impurity of Nabumetone (N200500), a non-steroidal anti-inflammatory drug, acting as anti-inflammatory agent.<br>References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006); Pinto-Bazurco, M. A. E., et al.: Bioorg. Med. Chem. Lett., 18, 267 (2008);<br></p>Formula:C22H18O2Color and Shape:NeatMolecular weight:314.38(±)-Carisoprodol-d7 (iso-propyl-d7)
CAS:Controlled Product<p>Applications (±)-Carisoprodol-d7 (iso-propyl-d7) (CAS# 1218911-01-3) is a useful isotopically labeled research compound. As a deuterated drug analog, this compound can be used for inter-patient variability.<br>References Gant, T., et.al., U.S. Pat. Appl. Publ., 28,(2010);<br></p>Formula:C12H17D7N2O4Color and Shape:NeatMolecular weight:267.38Nabumetone-d3
CAS:Controlled Product<p>Applications Labelled Nabumetone. Anti-inflammatory. Antibacterial.<br>References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006),<br></p>Formula:C152H3H13O2Color and Shape:NeatMolecular weight:231.30(+)-N,O-Didesmethyl Tramadol
CAS:Controlled Product<p>Applications An optically active metabolite of Tramadol.<br>References Garrido, M., et al.: J. Pharmacol. Exp. Ther., 305, 710 (2003), Pedersen, R., et al.: Eur. J. Clin. Pharmacol., 62, 513 (2006),<br></p>Formula:C14H21NO2Color and Shape:NeatMolecular weight:235.324-Morpholineethanol-d4
CAS:Controlled Product<p>Applications Labelled analogue 4-(2-Hydroxyethyl)morpholine, a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary culture/DNA.<br></p>Formula:C6H9D4NO2Color and Shape:NeatMolecular weight:135.205-(6-Methoxy-2-naphthalenyl)-3-methyl-2-cyclohexen-1-one
CAS:Controlled ProductFormula:C18H18O2Color and Shape:NeatMolecular weight:266.33Methyl 5-Methoxy-2-methylindole-3-acetate
CAS:Controlled Product<p>Applications Intermediate in the preparation of Indomethacin<br>References Kalgutkar, A.S., et al.: Bioorg. Med. Chem., 13, 6810 (2005),<br></p>Formula:C13H15NO3Color and Shape:NeatMolecular weight:233.26L-Propoxyphene-d5 HCl (propionyl-d5)
CAS:Controlled Product<p>Applications L-Propoxyphene-d5 Hydrochloride is the isotope labelled analog and L-isomer of Propoxyphene Hydrochloride (P831500); a controlled substance (opiate) and analgesic (narcotic). The α-DL-and D-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive. Oral administration of L-Propoxyphene Hydrochloride enhances the analgesic activity of D-Propoxyphene Hydrochloride.<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971); McEwan, B., et al.: Anal. Profiles Drug Subs., 1, 301 (1972); Murphy, P.J., et al.: J. Pharmacol. Exp. Ther., 199, 415 (1976)<br></p>Formula:C22H25D5ClNO2Color and Shape:NeatMolecular weight:380.963,4-Methylenedioxy Propiophenone
CAS:Controlled Product<p>Applications Intermediate in the production of Isosafrole and Ethylone.<br>References Katoch-Rouse, R., et al.: J. Med. Chem., 46, 642 (2003), Andrade, E., et al.: Chem. Biodivers., 5, 197 (2008),<br></p>Formula:C10H10O3Color and Shape:NeatMolecular weight:178.18(±)-Ibuprofen-d3, Sodium Salt (α-methyl-d3)
CAS:Controlled Product<p>Applications (±)-Ibuprofen-d3, Sodium Salt (alpha-methyl-d3) (CAS# 1219805-09-0) is a useful isotopically labeled research compound.<br></p>Formula:C13H14D3NaO2Color and Shape:NeatMolecular weight:231.29Nabumetone Dimer Impurity
CAS:Controlled Product<p>Impurity Nabumetone Dimer Impurity<br>Applications An impurity in a Nabumetone (N200500) drug substance.<br>References Friedel, H., et al.: Drugs, 35, 504 (1988), Davies, N., et al.: Clin. Pharmacokinet., 33, 403 (1997),<br></p>Formula:C27H26O3Color and Shape:NeatMolecular weight:398.49N-Desethyl 3-Bromo Lidocaine
CAS:Controlled Product<p>Applications Intermediate in the preparation of hydroxylated Lidocaine metabolites.<br></p>Formula:C12H17BrN2OColor and Shape:NeatMolecular weight:285.182-Hydroxy Nabumetone
CAS:Controlled ProductFormula:C15H18O2Color and Shape:White To Off-WhiteMolecular weight:230.306-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic
CAS:<p>6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, racemic is a drug product that is used as an analytical standard in the development of new drugs. It is also used to study the metabolism of drugs. 6BPDC has been shown to inhibit bacterial growth by binding to DNA and RNA, thereby preventing transcription and replication. This metabolite can be synthesized in the laboratory.</p>Formula:C15H13NO3Purity:Min. 95%Molecular weight:255.27 g/mol3-Carboxy-a-methyl-benzeneacetic acid
CAS:<p>3-Carboxy-a-methyl-benzeneacetic acid (3CMA) is an impurity in the synthesis of 3,4-methylenedioxyphenylacetone. It is a preservative that has been analysed as a potential source of contamination in pharmaceutical preparations. 3CMA has been shown to be effective at inhibiting the growth of bacteria, yeast and moulds. The analysis time for 3CMA is typically 8 hours or less. The parameters that are used to analyse 3CMA include the use of acetonitrile, optimal porosity and efficiency. The analytical methods used for 3CMA include chromatographic and chromolith methods.</p>Formula:C10H10O4Purity:Min. 95%Molecular weight:194.18 g/molPelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Formula:C16H18O3Purity:99.69%Color and Shape:SolidMolecular weight:258.31Nabumetone dimer
CAS:<p>Nabumetone is a nonsteroidal anti-inflammatory drug that is metabolized by the liver to form a dimer. The major metabolite of nabumetone is the dimer, which has been used as an impurity standard for this drug. Nabumetone has been shown to inhibit prostaglandin synthesis, and its metabolites have been studied for their effects on various enzymes.</p>Formula:C27H26O3Purity:Min. 95%Molecular weight:398.49 g/molN-(4-Hydroxyphenyl)propanamide
CAS:<p>The N-(4-hydroxyphenyl)propionamide (HPPA) is a synthetic drug that binds to the human liver. It has been shown to be effective in preventing implantation of fertilized eggs, and can be used as a diagnostic agent for determining the presence of HPPA in human liver tissue. HPPA is also used as a diluent for other drugs. The HPPA binds to chromatographic components and can be detected using electrochemical detection, which allows it to be used as a targetable probe for cancer research. HPPA is also used to study iontophoretic transport of ions across reconstituted membranes in vitro.</p>Formula:C9H11NO2Purity:(%) Min. 97%Molecular weight:165.19 g/molN-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium
CAS:Controlled Product<p>Please enquire for more information about N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C8H6D3NO5S•NaPurity:Min. 95%Molecular weight:257.24 g/mol(2-Amino-2-(hydroxymethyl)propane-3-ol-1-yl) (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate), racemic
<p>Racemic 2-amino-2-(hydroxymethyl)propane-3-ol-1-yl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate) is a synthetic drug product. It is used in research and development as an impurity standard. It is also used to synthesize drug products, which are custom synthesis and not commercially available. The racemate is a metabolite of the natural compound "Lysergic acid" and has been studied for its effects on metabolism.</p>Formula:C19H22N2O5Purity:Min. 95%Molecular weight:358.39 g/mol5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:<p>5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic (5BPC) is a drug that is used for the treatment of pain. It has been shown to be safe and effective in treating postoperative pain when given by intravenous infusion or as an oral tablet. 5BPC has minimal toxicity and is metabolized primarily by the liver with a half life of 2.6 hours. The drug has been found to have pharmacokinetic properties that allow it to be used safely in patients with hepatic impairment and in those recovering from abdominal surgery. 5BPC is a prodrug that undergoes biotransformation by esterases into its active form, pyrrolizidine alkaloid (PA). PA acts as a nonsteroidal anti-inflammatory agent and inhibits prostaglandin synthesis, which leads to analgesia. This drug also has minimal drug interactions because</p>Formula:C15H13O3NPurity:Min. 95%Molecular weight:255.27 g/molMavatrep
CAS:<p>Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.</p>Formula:C25H21F3N2OPurity:98.51% - 99.31%Color and Shape:SolidMolecular weight:422.44Meperidine Hydrochloride CII
CAS:Controlled ProductAlfentanil (inn), anileridine (inn), bezitramide (inn), bromazepam (inn), difenoxin (inn), diphenoxylate (inn), dipipanone (inn), fentanyl (inn), etc.Formula:C15H21NO2·HClColor and Shape:White Crystalline PowderMolecular weight:247.15723Tramadol Related Compound A CIV ((RS,SR)-1-(3-Methoxyphenyl)-2-(dimethylaminomethyl)cyclohexanol hydrochloride)
CAS:Controlled ProductAromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C16H25NO2·HClColor and Shape:White PowderMolecular weight:263.188533-Chloro-4-hydroxyacetanilide
CAS:<p>3-Chloro-4-hydroxyacetanilide is a chemical compound that belongs to the class of acetanilides. It has long-term toxicity and is used as a drug substance in the production of aniline derivatives. 3-Chloro-4-hydroxyacetanilide has been shown to be carcinogenic in hamsters. The long term exposure to this chemical was shown to cause liver damage and increased incidence of tumours in rats. This drug also contains impurities and traces of chloride, chlorine, and thionyl chloride, which are toxic substances that can cause irritation or burns on contact with skin or eyes.</p>Formula:C8H8ClNO2Purity:Min. 95%Molecular weight:185.61 g/molTramadol Hydrochloride CIV
CAS:Controlled ProductAromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C16H25NO2·HCIColor and Shape:White Crystalline PowderMolecular weight:403.10083JNJ-37822681 dihydrochloride
CAS:<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Formula:C17H19Cl2F5N4Purity:99.78%Color and Shape:SolidMolecular weight:445.26Pethidine Acid Methyl Ester (Meperidine Acid Methyl Ester; Methyl 1-Methyl-4-phenylpiperidine-4-carboxylate) 0.1 mg/ml in Methanol
CAS:Color and Shape:Single SolutionBenzoylphenylacetonitrile (3-Benzoylbenzeneacetonitrile)
CAS:Nitrile function compounds, nesoiFormula:C15H11NOMolecular weight:221.084062,4,5-Trimethylketoprofen ((2RS)-2-[3-(2,4,5-Trimethylbenzoyl)phenyl]propanoic Acid)
CAS:<p>Carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids andtheir deriv</p>Formula:C19H20O3Color and Shape:White Off-White SolidMolecular weight:296.14124Ref: 4Z-M-5323
Discontinued productRef: 4Z-M-6896
Discontinued productRef: 4Z-F-337
Discontinued productRef: 4Z-M-5315
Discontinued productTrinexapac-ethyl
CAS:<p>Trinexapac-ethyl is a useful organic compound for research related to life sciences. The catalog number is T65154 and the CAS number is 95266-40-3.</p>Formula:C13H16O5Color and Shape:SolidMolecular weight:252.27Ref: 4Z-M-5326
Discontinued productMetamizole EP Impurity E
CAS:Formula:C12H15N3O4SColor and Shape:White To Off-White SolidMolecular weight:297.33Ref: 4Z-M-538
Discontinued productRef: 4Z-M-105003
Discontinued productRef: 4Z-M-105002
Discontinued productRef: 4Z-M-6810
Discontinued productRef: 4Z-M-6862
Discontinued productRef: 4Z-M-5327
Discontinued productRef: 4Z-M-6897
Discontinued productRef: 4Z-A-0248
Discontinued productRef: 4Z-M-5328
Discontinued productRef: 4Z-A-0244
Discontinued product
![5′-Acetyl-2′-fluoro-3-methyl-[1,1′-biphenyl]-4-carbaldehyde](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF628194.webp&w=3840&q=75)
![1-(6-Fluoro-[1,1′-biphenyl]-3-yl)ethanone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF628181.webp&w=3840&q=75)
![1-[3-(ACETYLOXY)-4-METHOXYPHENYL]-ETHANONE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF467729.webp&w=3840&q=75)
