Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10373 products of "Benzimidazole and Imidazole Derivatives"
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Pantoprazole sodium hydrate - Mixture of impurities D and F
CAS:<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Formula:C17H17F2N3O4SPurity:Min. 95%Color and Shape:Off-white to yellow powder.Molecular weight:397.4 g/mol2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].</p>Formula:C15H15N3OS2Purity:Min. 95%Molecular weight:317.43 g/mol2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS:<p>Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.</p>Formula:C18H21N3O2SPurity:Min. 95%Color and Shape:White PowderMolecular weight:343.44 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide is an ammonium salt of a sulfoxide with a chloride. It is also known as esomeprazole magnesium. This drug is used in the preparation of pharmaceutical preparations and is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions. The magnesium salt form is a polymorphic substance that has a crystalline form that occurs in nature, called alpha form, and a synthetic form that occurs in laboratory experiments and has been designated beta form. The alpha form exhibits enantioselectivity when it binds to the enzyme pepsin, which causes the drug to have an antiulcer effect.</p>Formula:C17H19N3O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:361.42 g/molPantoprazole sulphone
CAS:<p>Pantoprazole sulphone is a proton-pump inhibitor that inhibits the production of stomach acid and protects the esophagus from damage. Pantoprazole sulphone has been shown to be effective in treating heart disease patients and reducing their risk of death. It also has biological properties, including modulating the effects of bosentan, which is used to treat pulmonary arterial hypertension. Pantoprazole sulphone has been shown to be chemically stable and stereoselective, which means it binds more strongly to one site than another. Clinical pharmacology studies have found that pantoprazole sulphone has no effect on abomasal motility or gastric emptying time.</p>Formula:C16H15F2N3O5SPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:399.37 g/mol2-Hydroxybenzimidazole
CAS:<p>2-Hydroxybenzimidazole is a benzimidazole compound that is used in the treatment of nervous system diseases. It has been shown to have anti-inflammatory properties and can be used in the treatment of syncytial virus infection. 2-Hydroxybenzimidazole inhibits the production of reactive oxygen species and nitric oxide, which are involved in neurodegenerative disorders. The mechanism of action for 2-Hydroxybenzimidazole involves the formation of hydrogen bonds with hydroxyl groups on proteins. It also has been shown to reduce locomotor activity and increase sleep time in mice, which may be due to inhibition of acetylcholine release from cholinergic neurons.</p>Formula:C7H6N2OPurity:Min. 97.5 Area-%Color and Shape:Off-White PowderMolecular weight:134.14 g/mol5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS:<p>5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.</p>Formula:C16H16ClN3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:349.84 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Formula:C16H17N3O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:315.39 g/mol6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
CAS:<p>6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is a metabolite that can be found in the urine and blood of humans. It has been shown to have cytotoxic effects on human lymphocytes and erythrocytes. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is used as an impurity standard for HPLC analysis and as a reference compound for pharmacopoeia. This chemical is also used in the synthesis of some drugs. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is not listed in any pharmacopoeia or natural product database.</p>Formula:C9H7Cl2N5Purity:Min. 95%Color and Shape:White PowderMolecular weight:256.09 g/mol1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine
CAS:<p>1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.</p>Formula:C24H27NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:377.48 g/molPantoprazole sulfide N-oxide
CAS:<p>Pantoprazole sulfide N-oxide is a metabolite of pantoprazole, which is a proton pump inhibitor used to reduce stomach acid production. Pantoprazole sulfide N-oxide is an impurity in pantoprazole that can be detected by HPLC. It has been shown to have about the same biological activity as pantoprazole when given orally.</p>Formula:C16H15F2N3O4SPurity:Min. 95%Color and Shape:Off-White To Yellow SolidMolecular weight:383.37 g/mol4-Isobutyl-2-pyrrolidinone
CAS:<p>4-Isobutyl-2-pyrrolidinone is a colorless liquid that belongs to the category of phosphites. It has a high boiling point, which makes it suitable for use in organic solvents and as a heat transfer agent. The thermodynamic properties of 4-Isobutyl-2-pyrrolidinone have been evaluated using the protonation theory. It can be protonated at either the nitrogen or the methyl group, and both forms are present in solution. This means that 4-Isobutyl-2-pyrrolidinone is acidic and can react with other compounds to form salts called lactams. There are two isomers of this compound: cis and trans. Both isomers exist in equilibrium; however, the cis isomer predominates at room temperature. The most common impurities of 4-Isobutyl-2-pyrrolidinone are dehydration products formed during synthesis or</p>Formula:C8H15NOPurity:Min. 95%Color and Shape:White PowderMolecular weight:141.21 g/molOmeprazole impurity F and G
CAS:<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Formula:C16H13N3O2SPurity:Min. 95%Color and Shape:Red PowderMolecular weight:311.36 g/mol2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole
CAS:<p>2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.</p>Formula:C18H21N3O4SPurity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:375.44 g/molCarbendazim
CAS:<p>Carbendazim is a fungicide that inhibits the growth of fungi and bacteria. It has been shown to be potent inducers of polymerase chain reaction (PCR) amplification, with a rate constant of 0.0103 per minute. Carbendazim also has a significant effect on electrochemical impedance spectroscopy (EIS). The EIS analysis was used to compare carbendazim-treated cells with untreated cells, which showed that carbendazim causes an increase in the resistance across the cell membrane. This research suggests that carbendazim may be genotoxic, as it increased the amount of DNA damage observed in wild-type strains and altered the optical properties of DNA. Carbendazim is also an effective inhibitor of nitrite ion oxidation and colloidal gold deposition, which has led to its use as a water vapor control agent for plants.</p>Formula:C9H9N3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:191.19 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole is an inhibitor of cytochrome P450 2C19. It has been shown to inhibit the activity of this enzyme in a concentration dependent manner and to enhance the activity of omeprazole by inhibiting its metabolism. 5-Methoxy-2-[(4-methoxy, 3,5 dimethylpyridiniumyl)methyl]sulfonyl]-1H benzimidazole is used as a model system for studying drug interactions due to its ability to inhibit cytochrome P450 2C19 and CYP2C19 protein expression. 5 METHOXY - 2 - [[ ( 4 - METHOXY - 3 , 5 - DIMETHYL - 2 - PYRIDINYL ) M</p>Formula:C17H19N3O4SPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:361.42 g/mol(1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl-2'-hydroxy-2',2'-di(thiophen-2''-yl)acetate
CAS:<p>Tanshinone IIA is an enantioselective hydroxamic acid that inhibits matrix metalloproteinase. It is a structural analogue of the hydroxamic acid Tanshinone I and has been shown to inhibit aggrecanase, which is an enzyme that hydrolyzes the glycosaminoglycan aggrecan. It also has anti-cancer effects due to its inhibition of cell proliferation in cancer cells. Tanshinone IIA can be used as a chiral synthon for polymerase chain reactions (PCR) because it contains a stereogenic centre in its structure.</p>Formula:C18H19NO3S2Purity:Min. 95%Color and Shape:PowderMolecular weight:361.48 g/mol2-Mercaptobenzimidazole
CAS:<p>2-Mercaptobenzimidazole is a chemical compound that can be used for the treatment of infectious diseases. It has been shown to have antioxidative properties and inhibit the growth of bacteria. 2-Mercaptobenzimidazole also has an effect on human serum, which may be due to its ability to bind with proteins in serum and form hydrogen bonds. 2-Mercaptobenzimidazole is stable at high temperatures and has been shown as an effective antimicrobial agent against gram positive and gram negative bacteria.</p>Formula:C7H6N2SPurity:Min. 99 Area-%Color and Shape:White/Off-White SolidMolecular weight:150.19 g/molVarenicline
CAS:<p>Varenicline (CP 526555) is a selective partial agonist of the α4β2 nAChR and a full agonist of the α3β4 nAChR and α7 nAChR.</p>Formula:C13H13N3Purity:99.76%Color and Shape:SolidMolecular weight:211.265-BROMO-6-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID
CAS:Formula:C8H4BrClN2O2Purity:97%Molecular weight:275.496-Bromo-3-methoxy-1H-indazole
CAS:Formula:C8H7BrN2OPurity:96%Color and Shape:SolidMolecular weight:227.0613-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indazole
CAS:Purity:98%Molecular weight:258.1300049Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-6-carboxylate
CAS:Purity:97%Molecular weight:302.14001464-Methyl-oxazole-5-carboxylic acid ethyl ester
CAS:Formula:C7H9NO3Purity:95%Color and Shape:SolidMolecular weight:155.153[5-(methoxymethyl)-1,3-oxazol-4-yl]methanol
CAS:Purity:98%Color and Shape:LiquidMolecular weight:143.1419983Ref: 10-F718531
1g790.00€5g2,158.00€10g3,180.00€2.5g1,452.00€50mg171.00€100mg261.00€250mg413.00€500mg612.00€7-Bromo-5-nitro-1H-indazole
CAS:Formula:C7H4BrN3O2Purity:95%Color and Shape:No data available.Molecular weight:242.0321-Boc-5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS:Formula:C18H25BN2O4Purity:97%Color and Shape:SolidMolecular weight:344.22Ethyl 2-bromo-1H-imidazole-5-carboxylate
CAS:Formula:C6H7BrN2O2Purity:98%Color and Shape:SolidMolecular weight:219.0387-(Diethylamino)-3-(1-methyl-1H-benzo[d]imidazol-2-yl)-2H-chromen-2-one
CAS:Formula:C21H21N3O2Purity:98%Molecular weight:347.418Chloro [1,3-Bis(2,6-di-I-propyl-phenyl)imidazol-2-ylidene]copper(1)
CAS:Formula:C27H36ClCuN2Purity:95%Color and Shape:SolidMolecular weight:487.62-Methyl-5-nitro-1H-benzoimidazole
CAS:Formula:C8H7N3O2Purity:97%Color and Shape:SolidMolecular weight:177.1632-Amino-5-bromobenzimidazole
CAS:Formula:C7H6BrN3Purity:95%Color and Shape:SolidMolecular weight:212.055-Amino-1,3-dimethyl-1,3-dihydro-benzoimidazol-2-one
CAS:Formula:C9H11N3OPurity:95%Color and Shape:SolidMolecular weight:177.207(1-Methyl-1H-indazol-6-yl)methanol
CAS:Formula:C9H10N2OPurity:97%Color and Shape:SolidMolecular weight:162.192(S)-3-((Benzyloxy)carbonyl)oxazolidine-4-carboxylic acid
CAS:Formula:C12H13NO5Purity:95%Molecular weight:251.2381H-INDAZOLE-6-SULFONYL CHLORIDE
CAS:Formula:C7H5ClN2O2SPurity:95%Color and Shape:SolidMolecular weight:216.64(1-Methyl-1H-indazol-7-yl)boronic acid
CAS:Formula:C8H9BN2O2Purity:98%Color and Shape:SolidMolecular weight:175.986-Methoxy-1H-indazol-5-amine
CAS:Formula:C8H9N3OPurity:97%Color and Shape:LiquidMolecular weight:163.184-Bromo-2-nitro-1H-imidazole
CAS:Formula:C3H2BrN3O2Purity:97%Color and Shape:SolidMolecular weight:191.9723-Iodo-7-nitro-1H-indazole
CAS:Formula:C7H4IN3O2Purity:98%Color and Shape:SolidMolecular weight:289.0322-Methyl-1H-imidazole-4-carbaldehyde
CAS:Formula:C5H6N2OPurity:97%Color and Shape:SolidMolecular weight:110.1162-Bromo-1-methyl-1H-imidazole
CAS:Formula:C4H5BrN2Purity:97%Color and Shape:LiquidMolecular weight:161.0021-(Tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS:Purity:96%Molecular weight:328.2200012Tert-butyl (S)-2-(5-iodo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS:Purity:98%Molecular weight:363.19900511-(4-Methyl-1H-imidazol-2-yl)ethanone
CAS:Formula:C6H8N2OPurity:95+%Color and Shape:SolidMolecular weight:124.1434-Trifluoromethyl-oxazol-2-ylamine
CAS:Formula:C4H3F3N2OPurity:98%Color and Shape:SolidMolecular weight:152.0761H-Benzimadazole-5-carboxylic acid
CAS:Formula:C8H6N2O2Purity:95%Color and Shape:SolidMolecular weight:162.1484-Chloro-1H-indazol-3-amine
CAS:Formula:C7H6ClN3Purity:98%Color and Shape:SolidMolecular weight:167.0256-Bromo-5-fluoro-3-methyl-1H-indazole
CAS:Formula:C8H6BrFN2Purity:97%Color and Shape:Liquid, No data available.Molecular weight:229.052tert-Butyl oxazol-4-ylcarbamate
CAS:Formula:C8H12N2O3Purity:97%Color and Shape:SolidMolecular weight:184.1956-(Methoxycarbonyl)-1H-indazole-3-carboxylic acid
CAS:Formula:C10H8N2O4Purity:98%Molecular weight:220.1842,4-Dibromo-1-methyl-1H-imidazole
CAS:Formula:C4H4Br2N2Purity:98%Color and Shape:SolidMolecular weight:239.8981-(1H-Indazol-1-yl)ethanone
CAS:Formula:C9H8N2OPurity:98%Color and Shape:SolidMolecular weight:160.1765-BROMO-1-(TETRAHYDRO-2H-PYRAN-2-YL)-1H-INDAZOLE
CAS:Formula:C12H13BrN2OPurity:98+%Molecular weight:281.153Ref: 10-F530668
1g124.00€5g530.00€10g1,042.00€2.5g283.00€50mg79.00€100mg83.00€250mg90.00€500mg112.00€6-Amino-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride
CAS:Purity:95%Molecular weight:199.63999941-Methyl-1H-indazole-3-carbaldehyde
CAS:Formula:C9H8N2OPurity:97%Color and Shape:SolidMolecular weight:160.1762,3-DIMETHYL-2H-INDAZOLE-6-BORONIC ACID PINACOL ESTER
CAS:Formula:C15H21BN2O2Purity:98%Molecular weight:272.161-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDAZOLE
CAS:Formula:C14H19BN2O2Purity:97%Molecular weight:258.135-Methyl-6-nitro-1H-indazole
CAS:Formula:C8H7N3O2Purity:98%Color and Shape:SolidMolecular weight:177.0546-Bromo-3-chloro-1H-indazole
CAS:Formula:C7H4BrClN2Purity:98%Color and Shape:Solid, Yellow solidMolecular weight:229.925(R)-methyl 5-(6-(hydroxymethyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxylate
CAS:Purity:95%Molecular weight:476.47000126-Bromo-1H-indazole-4-carboxylic acid
CAS:Formula:C8H5BrN2O2Purity:98%Color and Shape:SolidMolecular weight:239.953
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