Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10375 products of "Benzimidazole and Imidazole Derivatives"
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1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic Acid
CAS:Controlled Product<p>Applications 1-(4-Chloro-2-(2-fluorobenzoyl)phenyl)-2-methyl-1H-imidazole-5-carboxylic Acid is a metalobilite of Midazolam(M343000) which is a anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000),<br></p>Formula:C18H12ClFN2O3Color and Shape:NeatMolecular weight:358.75Albendazole
CAS:<p>Applications Albendazole is an anthelmintic drug.<br>References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008); Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009);<br></p>Formula:C12H15N3O2SColor and Shape:Off WhiteMolecular weight:265.33Miconazole Impurity I
CAS:Controlled Product<p>Impurity Miconazole EP Impurity I<br>Applications Miconazole Impurity I (Miconazole EP Impurity I), is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H15Cl3N2OColor and Shape:NeatMolecular weight:381.683Benzoylmetronidazole
CAS:Controlled Product<p>Applications Benzoylmetronildazole is a new class of antiglycation agents used to treat diabetes mellitus. Benzoylmetronildazole is also a derivative of Metronidazole (M338880), an antibacterial in the treatment of rosacea.<br>References Zeb, A., et al.: Med. Chem., 8, 846 (2012); Kumari, N., et al.: Curr. Drug. Deliv., 9, 74 (2012); Elosta, A., et al.: Curr. DIabetes. Rev., 8, 92 (2012);<br></p>Formula:C13H13N3O4Color and Shape:WhiteMolecular weight:275.26rac-Pregabalin
CAS:Controlled Product<p>Applications A GABA analogue used as an anticonvulsant.Controlled substance in the United States.Not controlled in Germany<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H17NO2Color and Shape:White SolidMolecular weight:159.23Triclabendazole Sulfoxide-D3
CAS:Controlled Product<p>Applications Triclabendazole Sulfoxide-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14H6D3Cl3N2O2SColor and Shape:NeatMolecular weight:378.68(3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione
CAS:Controlled Product<p>Applications (3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione is a reagent used in the synthesis of Pregabalin (P704800), a GABA analogue used as an anticonvulsant. Also used to prepare P2X7 receptor antagonists.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999); Eur. J. Org. Chem., 2013, 4495 (2013); Yang, H. et al.: Chinese. Chem. Lett., 24, 553 (2013);<br></p>Formula:C8H10O3Color and Shape:NeatMolecular weight:154.163,5-Didesamino-3,5-dioxo Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity D<br>Applications 3,5-Didesamino-3,5-dioxo Lamotrigine (Lamotrigine EP Impurity D) is an impurity of the anticonvulsant Lamotrigine (L173250).<br>References Hlavac, J. et al.: ARKIVOC, 1, 22 (2003);<br></p>Formula:C9H5Cl2N3O2Color and Shape:NeatMolecular weight:258.065-Hydroxy Thiabendazole
CAS:Controlled Product<p>Applications 5-Hydroxy Thiabendazole is the major metabolite of Thiabendazole (T344150).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujitani, T., et al.: Food Chem. Toxicol., 29, 265 (1991), Mizutani, T., et al.: Chem. Res. Toxicol., 6, 174 (1993), Dalvie, D., et al.: J. Agric. Food Chem., 42, 2964 (2006),<br></p>Formula:C10H7N3OSColor and Shape:Light YellowMolecular weight:217.25Lamotrigine 5,5-Dimer
Controlled Product<p>Applications Lamotrigine 5,5-Dimer is a dimer impurity of the anticonvulsant Lamotrigine (L173250).<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C19H14Cl4N10Color and Shape:Off White SolidMolecular weight:524.19Triazolam
CAS:Controlled Product<p>Applications Sedative, hypnotic.Controlled substance (depressant).<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4Color and Shape:WhiteMolecular weight:343.21Carbamazepine 10,11-Epoxide-d8 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Carbamazepine (C175840).<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H4D8N2O2Color and Shape:White To Dark YellowMolecular weight:260.32Itraconazole-d3
CAS:Controlled ProductFormula:C352H3H35Cl2N8O4Color and Shape:NeatMolecular weight:708.65Modafinil Carboxylate Methyl Ester
CAS:Controlled Product<p>Impurity Modafinil EP Impurity C<br>Applications Modafinil Carboxylate Methyl Ester (Modafinil EP Impurity C) is a Modafinil derivative.<br>References Lehr, H., et al.: J. Med. Chem., 6, 136 (1963), Saikawa, I., et al.: Chem. Pharm. Bull., 33, 5534 (1985),<br></p>Formula:C16H16O3SColor and Shape:NeatMolecular weight:288.363-Methoxy-temazepam
CAS:Controlled ProductFormula:C17H15ClN2O2Color and Shape:Off-White To Light YellowMolecular weight:314.77N-Desmethyl,-N-nitroso-promethazine
CAS:Controlled ProductFormula:C16H17N3OSColor and Shape:NeatMolecular weight:299.392-Imidazol-1-yl-benzylamine
CAS:Formula:C10H11N3Purity:95.0%Color and Shape:AmorphousMolecular weight:173.219N-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl Lansoprazole
CAS:Controlled Product<p>Applications Lansoprazole (L175000) impurity.<br>References Wallmark, B., et al.: J. Gastroenterol., 20, 37 (1985), Barradell, L., et al.: Drugs, 44, 225 (1992), Reddy, K., et al.: Pharmazie, 65, 994 (2006),<br></p>Formula:C25H22F6N4O3SColor and Shape:Beige To Light BrownMolecular weight:572.52Secnidazole
CAS:Controlled Product<p>Applications Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H11N3O3Color and Shape:White To Light YellowMolecular weight:185.18
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