Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10354 products of "Benzimidazole and Imidazole Derivatives"
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5-(4-chlorophenyl)-1-(2-methoxyphenyl)-2,3-dihydro-1H-imidazole-2-thione
Molecular weight:316.79998779296875Methyl Methanethiosulfonate
CAS:Controlled ProductFormula:C2H6O2S2Color and Shape:NeatMolecular weight:126.20Hydroxy Itraconazole-d5
CAS:Controlled ProductFormula:C35D5H33Cl2N8O5Color and Shape:Off-WhiteMolecular weight:726.66Albendazole Sulfoxide-d7
CAS:Controlled Product<p>Applications Albendazole Sulfoxide-d7 is the isotope labelled metabolite of Albendazole (A511620), an anthelmintic agent.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol Lett., 6, 2: 51 (1996)<br></p>Formula:C12H8D7N3O3SColor and Shape:NeatMolecular weight:288.37Temazepam Acetate
CAS:Controlled Product<p>Applications Temazepam Acetate is an impurity of temazepam (T017200), which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C18H15ClN2O3Color and Shape:White To Off-WhiteMolecular weight:342.78Secnidazole-d3
CAS:Controlled Product<p>Applications Labelled Secnidazole (S225000). Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H8D3N3O3Color and Shape:White To Off-WhiteMolecular weight:188.2(S)-Pregabalin Lactam
CAS:<p>Impurity Pregabalin EP impurity A<br>Applications (S)-Pregabalin Lactam is an impurity of (S)-Pregabalin (P704790) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColor and Shape:WhiteMolecular weight:141.213,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C10H12O5Color and Shape:White To BeigeMolecular weight:212.205-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole
CAS:Controlled Product<p>Applications 5-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole is an impurity of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C16H17N3O2Color and Shape:NeatMolecular weight:283.33Clotrimazole
CAS:<p>Applications Clotrimazole is an antifungal agent.<br>References Podust, L., et al.: J. Biol. Chem., 284, 25211 (2009), Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009), Marciniec, B., et al.: J. Pharm. Biomed. Anal., 50, 675 (2009), McGinnity, D., et al.: Drug Metab. Disposition, 37, 1259 (2009),<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.842,3-Dichlorobenzoyl Nitrile
CAS:Controlled Product<p>Applications 2,3-Dichlorobenzoyl Nitrile is an impurity of Lamotrigine (L173250), an anticonvulsant that is used in the treatment of bipolar and depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rao, S.N., et al.: Int. J. Pharma. Pharmaceut. Sci., 4, 133 (2012); Qian, Y., et al.: J. Chem. Sci., 121, 463 (2009);<br></p>Formula:C8H3Cl2NOColor and Shape:NeatMolecular weight:200.02Letrozole
CAS:<p>Applications A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995),<br></p>Formula:C17H11N5Color and Shape:YellowMolecular weight:285.305-Phenylthio-2-aminobenzimidazole
CAS:Controlled Product<p>Applications 5-Phenylthio-2-aminobenzimidazole, is a derivative of Fenbendazole (F246750), an anthelmintic.<br>References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),<br></p>Formula:C13H11N3SColor and Shape:Light Brown To OrangeMolecular weight:241.31Rufinamide-d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N4OColor and Shape:White To Light YellowMolecular weight:240.21Benznidazole
CAS:<p>Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.<br>References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),<br></p>Formula:C12H12N4O3Color and Shape:NeatMolecular weight:260.25Efinaconazole
CAS:Controlled Product<p>Applications Efinaconazole is a topical antifungal for onychomycosis. (Synonyms: KP-103)<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4OColor and Shape:NeatMolecular weight:348.39
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