Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10353 products of "Benzimidazole and Imidazole Derivatives"
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Albendazole Sulfone-d7
CAS:Controlled Product<p>Applications Albendazole Sulfone-d7 is the isotope labelled metabolite of Albendazole (A511610), an anthelmintic agent.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol. Lett., 6, 2: 51 (1996)<br></p>Formula:C12H8D7N3O4SColor and Shape:NeatMolecular weight:304.37Diethyl Rivastigmine
CAS:Controlled Product<p>Applications An impurity in Rivastigmine (R541000), a cholinesterase inhibitor.<br>References Tse, F., et al.: Pharm. Res., 15, 1614 (1998), Melchiorre, C., et al.: J. Med. Chem., 47, 5945 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 57 (2005),<br></p>Formula:C15H24N2O2Color and Shape:NeatMolecular weight:264.3633Nimorazole
CAS:Controlled Product<p>Applications Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa.<br>References Ratnaparkhi, M.P., et al.: Res. J. Pharma. BIol. Chem. Sci., 3, 303 (2012); Toustrup, K., et al.: Radiotherap. Oncol., 102, 122 (2012);<br></p>Formula:C9H14N4O3Color and Shape:NeatMolecular weight:226.232-Nitroaniline
CAS:Controlled Product<p>Impurity Albendazole Impurity 4<br>Applications 2-Nitroaniline, is the main precursor to phenylenediamines, which are converted to benzimidazoles, a family of heterocycles that are key components in pharmaceuticals. Albendazole Impurity 4<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Booth, G.,et al.: Ull. Encyc. Indust. Chem. (2007);<br></p>Formula:C6H6N2O2Color and Shape:NeatMolecular weight:138.12Tinidazole-d5
CAS:Controlled Product<p>Applications Labelled Tinidazole. Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H8D5N3O4SColor and Shape:NeatMolecular weight:252.3Iminostilbene N-Carbonyl Chloride
CAS:<p>Impurity Carbamazepine EP Impurity F<br>Stability Hygroscopic, Moisture Sensitive<br>Applications Iminostilbene N-Carbonyl Chloride is an intermediate in the preparation of Carbamazepine (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Takayama, H., et al.: Bioorg. Med. Chem. Lett., 17, 4729 (2007),<br></p>Formula:C15H10ClNOColor and Shape:NeatMolecular weight:255.704-(4-Cyanobenzyl)-1,2,4-triazole
CAS:Controlled Product<p>Applications 4-(4-Cyanobenzyl)-1,2,4-triazole is an intermediate in the synthesis of Letrozole (L330100), an oral, non-steroidal, aromatase inhibitor generally used to treat breast cancer as a result of hormone response after surgery.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995),<br></p>Formula:C10H8N4Color and Shape:NeatMolecular weight:184.20Scopolamine N-Oxide
CAS:<p>Stability Hygroscopic<br>Applications Scopolamine N-Oxide is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.<br>References Shahwar, D., et al.: Turk. J. Chem., 36, 257 (2012); Paula, S., et al.: J. Med. Chem., 47, 133 (2004); Wu, H.L., et al.: J. Chromatograph. A., 802, 107 (1998); Phillipson, J.D., et al.: J. Pharma. Pharmcol., 25, 116 (1973);<br></p>Formula:C17H21NO5Color and Shape:NeatMolecular weight:319.352-(2-Cyclopropyl-6-fluoro-1H-1,3-benzodiazol-1-yl)acetic acid
CAS:Molecular weight:234.22999572753906Omeprazole-d3
CAS:Controlled Product<p>Applications Labelled Omeprazole, which binds covalently to proton pump, it inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C172H3H16N3O3SColor and Shape:NeatMolecular weight:348.43Benznidazole-d7
CAS:Controlled Product<p>Applications Benznidazole-D7 is a labelled analogue of Benznidazole (B197925).<br></p>Formula:C12H5D7N4O3Color and Shape:NeatMolecular weight:267.29(2-Chlorophenyl)diphenylmethanol
CAS:<p>Impurity Clotrimazole EP Impurity A<br>Applications (2-Chlorophenyl)diphenylmethane (Clotrimazole EP Impurity A) is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is a degradation product of the antifungal agent Clotrimazole (C587400). Clotrimazole Related Compound A<br>References Suzuki, M. Iyak. Kenk., 23, 44 (1992); Hajkova, R. et al.: Talanta, 73, 483 (2007); Sabourin, L. et al.: Environ. Toxicol. Chem., 30, 582 (2011);<br></p>Formula:C19H15ClOColor and Shape:NeatMolecular weight:294.77Lansoprazole N-Oxide
CAS:Controlled Product<p>Impurity Lansoprazole EP Impurity A<br>Applications Lansoprazole N-Oxide (Lansoprazole EP Impurity A) is an impurity of Lansoprazole (L175000) formed during the bulk synthesis of the drug.<br>References Kubo, K., et al.: Chem. Pharm. Bull., 38, 2853 (1990), Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.365-Acetyl-10,11-dihydro-5H-dibenzo[b,f]azepine
CAS:Controlled Product<p>Impurity Carbamazepine Impurity 2<br>Applications 5-Acetyl-10,11-dihydro-5H-dibenzo[b,f]azepine, is Dibenz[b,f]azepine derivative, possessing antioxidant potentials. It is also an analogue of Imipramine (I465980), and Desipramine (D290050). Carbamazepine Impurity 2.<br>References Kumar, H. V., et al.: E- J. Chem., 5, 1123 (2008); Bhattacharjee, A. K., et al.: J. Chem. Info. Comp. Sci., 42 (2002);<br></p>Formula:C16H15NOColor and Shape:NeatMolecular weight:237.304-Hydroxy Omeprazole Preparation Kit
CAS:Controlled ProductFormula:C16H17N3O3SColor and Shape:Off White SolidMolecular weight:331.39N-Formyl Oxcarbazepine
CAS:Controlled Product<p>Applications N-Formyl Oxcarbazepine is an impurity of the anticonvulsant Oxcarbazepine (O869250).<br></p>Formula:C16H12N2O3Color and Shape:NeatMolecular weight:280.28N-Nitroso Varenicline
CAS:Controlled Product<p>Applications N-Nitroso Varenicline is a derivative of Varenicline (V215635(M)), which is a useful medication for smoking cessation.<br>References Hart, E., et al.: Behavioural Brain Research, 397, 112887 (2021)<br></p>Formula:C13H12N4OColor and Shape:NeatMolecular weight:240.261Itraconazole-d9
CAS:Controlled Product<p>Applications Itraconazole-d9, is the labeled analogue of Itraconazole (I937500, an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M., et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C35H29D9Cl2N8O4Color and Shape:Off-White To BeigeMolecular weight:714.69Rivastigmine Tartrate Salt
CAS:Controlled ProductFormula:C14H22N2O2·C4H6O6Color and Shape:White To Off-WhiteMolecular weight:400.42
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