Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10375 products of "Benzimidazole and Imidazole Derivatives"
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Omeprazole-d3 Sulfone
CAS:Controlled ProductFormula:C17H16D3N3O4SColor and Shape:NeatMolecular weight:364.43Midazolam 2-Oxide
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000).<br></p>Formula:C18H13ClFN3OColor and Shape:NeatMolecular weight:341.77Oxcarbazepine-D4 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.Only available as a mixture of deuterated material:d-1: 1%d-2: 9%d-3: 35%d-4: 55%<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Formula:C152H4H8N2O2Color and Shape:Light Orange Colour PowderMolecular weight:256.299-Hydroxy Propantheline Bromide
CAS:<p>Applications A major impurity of the antimuscarinic agent Propantheline Bromide (P760900).<br>References Ford, B.L. et al.: J. Assoc. Off. Anal. Chem., 67, 934 (1984); Mourier, P.A.: Analusis, 17, 67 (1989);<br></p>Formula:C23H30NO4·BrColor and Shape:NeatMolecular weight:464.39(R)-Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity D<br>Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);<br></p>Formula:C14H22N2O2·C4H6O6Color and Shape:NeatMolecular weight:400.42rac 4,5-Dehydro Pregabalin
CAS:<p>Stability Hygroscopic<br>Applications 4,5-Dehydropregabalin is an impurity of the anticonvulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Color and Shape:NeatMolecular weight:157.214-Desmethoxypropoxyl-4-chloro Rabeprazole
CAS:Controlled Product<p>Impurity Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)<br>Applications 4-Desmethoxypropoxyl-4-chloro Rabeprazole (Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)) is a process impurity of Rabeprazole (R070500).<br></p>Formula:C14H12ClN3OSColor and Shape:NeatMolecular weight:305.78Metronidazole-d4
CAS:Controlled Product<p>Applications Metronidazole-d4 is a labelled analog of Metronidazole (M338880). Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C62H4H5N3O3Color and Shape:Light YellowMolecular weight:175.18Carbamazepine-d2,15N
CAS:Controlled ProductFormula:C15H10D2N15NOColor and Shape:Off White SolidMolecular weight:239.27Lansoprazole-d4
CAS:Controlled ProductFormula:C162H4H10F3N3O2SColor and Shape:NeatMolecular weight:373.39Isobutylsuccinic Acid
CAS:Controlled Product<p>Applications Isobutylsuccinic Acid was used to synthesize succinimide derivatives as inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.<br>References Groutas, W., et al.: Bioorg. Med. Chem., 3, 375 (1995);<br></p>Formula:C8H14O4Color and Shape:NeatMolecular weight:174.19Midazolam
CAS:Controlled Product<p>Applications Anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3Color and Shape:White To Off-WhiteMolecular weight:325.773-Cyano-5-methylhexanoic Acid
CAS:Controlled Product<p>Applications 3-Cyano-5-methylhexanoic Acid, a derivative of rac-Pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Taylor, C. at al.: Epilepsy Res., 14, 11 (1993); Field, M. et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H13NO2Color and Shape:NeatMolecular weight:155.19((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone
CAS:Controlled Product<p>Impurity Solifenacin EP Impurity D<br>Applications ((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColor and Shape:NeatMolecular weight:444.57N-Ethyl-N-(4-picolyl)atropamide (>85%)
CAS:<p>Stability Light Sensitive<br>Applications N-Ethyl-N-(4-picolyl)atropamide is a major impurity of Tropicamide (T892650), a medication used to dilate the pupil.<br>References Stefanowicz, Zdzislawa, et al.: J. of Pharma. and Biomed. Analy., 49(2), 214-220 (2009)<br></p>Formula:C17H18N2OPurity:>85%Color and Shape:NeatMolecular weight:266.34Ilaprazole
CAS:Controlled Product<p>Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.<br>References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)<br></p>Formula:C19H18N4O2SColor and Shape:NeatMolecular weight:366.442-Cyclohexyl-2-hydroxy-phenylacetic Acid
CAS:Controlled Product<p>Impurity Oxybutynin USP Related Compound A<br>Applications An intermediate in the synthesis of oxybutynin (O868525). Oxybutynin USP Related Compound A.<br></p>Formula:C14H18O3Color and Shape:WhiteMolecular weight:234.292-Phenyl-1H-benzo[d]imidazole-5-sulfonic acid
CAS:Purity:95.0%Color and Shape:Solid, White - Pale yellow powderMolecular weight:274.2900085449219O-Hydroxyethyl Metronidazole
CAS:Controlled Product<p>Applications O-Hydroxyethyl Metronidazole is the hydroxy ethyl analogue and impurity of the antiprotozoal agent Metronidazole (M338880). O-Hydroxyethyl Metronidazole as well as other 1-substituted-2-methyl-5-nitroimidazoles showed potential antitrichomonal activity.<br>References Kajfez, F. et al.: J. Med. Chem., 11, 167 (1968);<br></p>Formula:C8H13N3O4Color and Shape:Yellowish SolidMolecular weight:215.21(S)-Pregabalin-13C3
CAS:Controlled Product<p>Applications (S)-Pregabalin-13C3, is the labeled analogue of (S)-Pregabalin (P704790), a S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C513C3H17NO2Color and Shape:Off-WhiteMolecular weight:162.2
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