Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity
CAS:Controlled Product<p>Applications Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C34H36Cl2N8O5Color and Shape:NeatMolecular weight:707.612,4-Dicyano-3-(2-methylpropyl)-pentanediamide (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygrscopic<br>Applications 2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.<br>References Hoekstra, M.S., et al.: Org. Proc. Rec. Deve., 1, 26 (1997); Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951); Gerlach, M., et al.: Brain Res., 741, 142 (1996); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C11H16N4O2Color and Shape:NeatMolecular weight:236.27Isometronidazole-D4
CAS:Controlled Product<p>Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6D4H5N3O3Color and Shape:NeatMolecular weight:175.18N-Methyl Omeprazole-d3 (Mixture of isomers with the methylated nitrogens of imidazole)
CAS:Controlled Product<p>Applications Labelled Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formula:C18H18D3N3O3SColor and Shape:NeatMolecular weight:362.46rac-6-Chloro Voriconazole
CAS:Controlled Product<p>Applications An achiral intermediate of Voriconazole (V760000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferretti, R., et al.: Chromatographia, 47, 649 (1998),<br></p>Formula:C16H13ClF3N5OColor and Shape:NeatMolecular weight:383.76Solifenacin EP Impurity A Nitroso Impurity
Controlled ProductFormula:C15H14N2OColor and Shape:NeatMolecular weight:238.29Midazolam-d6 (1 mg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C18D6H7ClFN3Color and Shape:Single SolutionMolecular weight:331.80N-Nitroso Albendazole (mixtures of regional isomers)
Controlled ProductFormula:C13H16N4O3SColor and Shape:NeatMolecular weight:616.712N-Desmethyl Dextrorphan β-D-O-Glucuronide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled metabolite of Dextromethorphan.<br>References Gonzalez, F., et al.: Nature, 331, 442 (1988), Chen, S., et al.: Clin. Pharmacol. Ther., 60, 522 (1996), Hartter, S., et al.: Ther. Drug Monit., 18, 297 (1996), Garcia-Martin, E., et al.: Clin. Pharmacol. Ther., 71, 196 (2002),<br></p>Formula:C22H29NO7Color and Shape:NeatMolecular weight:419.47N-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl] Rabeprazole Sulfide
CAS:Controlled Product<p>Applications Rabeprazole (R070500) N-aralkyl impurity.<br>References Fujisaki, H., et al.: Biochem. Pharmacol., 42, 321 (1991), Morri, M., et al.: J. Biol. Chem., 268, 21553 (1993), Pingili, R., et al.: Pharmazie, 60, 814 (2005),<br></p>Formula:C29H36N4O4SColor and Shape:NeatMolecular weight:536.696-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline
CAS:Controlled Product<p>Applications 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline is a photochemical decomposition product of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Anderson, R., et al.: J. Pharma. Biomed. Anal., 13, 667 (1995); Anderson, R., et al: Am. Clin. Lab., 16, 25 (1997);<br></p>Formula:C15H10ClFN2Color and Shape:NeatMolecular weight:272.703-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS:Controlled Product<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C8H16BrNOColor and Shape:NeatMolecular weight:222.12Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Formula:C28H38N4O3SColor and Shape:NeatMolecular weight:510.69Propyl Itraconazole
CAS:Controlled ProductFormula:C34H36Cl2N8O4Color and Shape:NeatMolecular weight:691.61(S)-5,6-Dehydro Pregabalin
CAS:Controlled Product<p>Applications (S)-5,6-Dehydro Pregabalin is derived from rac 5,6-Dehydro Pregabalin (D230055), which is an impurity of the anti-convulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Color and Shape:NeatMolecular weight:157.211,2-Bismethylenecyclohexane (~75%)
CAS:Controlled ProductFormula:C8H12Purity:~75%Color and Shape:NeatMolecular weight:108.18Trimebutine-d9 Maleate Salt
CAS:Controlled Product<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C22H20D9NO5·C4H4O4Color and Shape:NeatMolecular weight:512.62,5-Dichlorothiophen-3-yl Tioconazole Hydrochloride
CAS:Controlled ProductFormula:C16H12Cl4N2OS·ClHColor and Shape:NeatMolecular weight:458.622-Chloroacetamide
CAS:Controlled Product<p>Applications A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aptula, A., et al.: Chem. Res. Toxicol., 19, 1097 (2006), Chan, K., et al.: J. Appl. Toxicol., 28, 608 (2008),<br></p>Formula:C2H4ClNOColor and Shape:WhiteMolecular weight:93.51
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