Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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Tiotropium-d6 Bromide
CAS:Controlled ProductFormula:C19H16D6BrNO4S2Color and Shape:White To PurpleMolecular weight:478.45Isopropyl Itraconazole
CAS:Controlled ProductFormula:C34H36Cl2N8O4Color and Shape:NeatMolecular weight:691.61(E)-Ethyl 2-cyano-5-methylhex-2-enoate
CAS:Controlled ProductFormula:C10H15NO2Color and Shape:NeatMolecular weight:335.429Butyl Itraconazole
CAS:Controlled ProductFormula:C35H38Cl2N8O4Color and Shape:NeatMolecular weight:705.635,6-Dimethoxyindane-1,3-dione
CAS:Controlled ProductFormula:C11H10O4Color and Shape:NeatMolecular weight:206.19(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Controlled ProductFormula:C13H15F2N3O4SColor and Shape:NeatMolecular weight:347.348-Demethyl Zolazepam
CAS:Controlled Product<p>Applications N-Demethylated metabolite of the anesthetic agent, Zolazepam (Z613500).<br>References Baukema, J. et al.: Res. Comm. Chem. Pathol. Pharmacol., 10, 227 (1975);<br></p>Formula:C14H13FN4OColor and Shape:NeatMolecular weight:272.2810-Methoxy-5H-dibenz[b,f]azepine-5-carbonyl chloride
CAS:Controlled ProductFormula:C16H12ClNO2Color and Shape:NeatMolecular weight:286.002-Chlorobenzotrichloride
CAS:Controlled Product<p>Applications 2-Chlorobenzotrichloride is a chlorinated toluene with mutagenicity.<br>References Mineki, S. et al.: Mat. technol., 23, 413 (2005); Matsushita, H. et al.: Indust. Health., 17, 199 (1979);<br></p>Formula:C7H4Cl4Color and Shape:NeatMolecular weight:229.92trans-Itraconazole
CAS:Controlled Product<p>Impurity Itraconazole EP Impurity E<br>Applications trans-Itraconazole (Itraconazole EP Impurity E) is a geometrical isomer of Itraconazole (I937500). It is a COVID19-related research product.<br>References Ahn, C., et al.: J. Korean Chem. Soc., 43, 676 (1999),<br></p>Formula:C35H38Cl2N8O4Color and Shape:NeatMolecular weight:705.63(Chloromethyl)cyclohexane
CAS:Controlled Product<p>Applications (Chloromethyl)cyclohexane is a common chemical reagent used in the synthesis of imidazole inhibitors of cytokine release which suppresses the response to tumor necrosis factor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laufer, S. et al., J. Med. Chem., 45, 1695 (2002); Rabinowitz, M. et al.: J. Med. Chem., 44, 4252 (2001);<br></p>Formula:C7H13ClColor and Shape:NeatMolecular weight:132.63Propyl Itraconazole
CAS:Controlled ProductFormula:C34H36Cl2N8O4Color and Shape:NeatMolecular weight:691.612,2'-Ethylenedianiline
CAS:Controlled Product<p>Applications 2,2'-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2'-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity.<br>References Asmaa, M., et al.: Pac. J. Cancer Prevent., 15, 475 (2014); Kalis, M. & Huff, N.: Clin. Ther., 23, 680 (2001); Malke, S., et al.: Pharm. Sci., 69, 211 (2007); Schmidt, D. & Elger, C.: Epil. Beh., 5, 627 (2004)<br></p>Formula:C14H16N2Color and Shape:NeatMolecular weight:212.29(S)-Modafinil-d10
CAS:Controlled Product<p>Applications Labelled (S)-Modafinil. Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219 (2002), Dinges, D., et al.: Curr. Med. Res. Opin., 22, 159 (2006)<br></p>Formula:C15D10H5NO2SColor and Shape:NeatMolecular weight:283.41N-Ethylcarbamic Acid 3-[(1S)-1-(Dimethylamino)ethyl]phenyl Ester
CAS:Controlled ProductFormula:C13H20N2O2Color and Shape:NeatMolecular weight:236.31cis-Hydroxy Solifenacin N-Oxide(Mixture of Diastereomers)
Controlled Product<p>Applications Solifenacin (S676700) metabolite.<br></p>Formula:C23H26N2O4Color and Shape:NeatMolecular weight:394.46Noratropine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Atropine (A794625). Two metabolites of Atropine (apoatropine and noratropine) were found in rat urine.<br>References Xu, A., et al.: J. Pharm. Biomed. Anal., 14, 33 (1995), Cherkaoui, S., et al.: J. Pharm. Biomed. Anal., 17, 1167 (1998),<br></p>Formula:C16H21NO3·HClColor and Shape:BrownMolecular weight:311.80Isometronidazole-D4
CAS:Controlled Product<p>Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6D4H5N3O3Color and Shape:NeatMolecular weight:175.18rac N-Demethyl Promethazine-d3 Hydrochloride
CAS:Controlled Product<p>Applications Labelled Promethazine (P757000) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keipert, S., et al.: Pharmazie, 31, 296 (1976),<br></p>Formula:C16H16D3ClN2SColor and Shape:NeatMolecular weight:309.874-Hydroxy Midazolam-d5 Methanoate
CAS:Controlled Product<p>Applications A labelled metabolite of Midazolam (M343000).<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006),<br></p>Formula:C19H12D5ClFN3O2Color and Shape:NeatMolecular weight:378.844-Acetoxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000).<br></p>Formula:C20H15ClFN3O2Color and Shape:NeatMolecular weight:383.80(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS:Controlled ProductFormula:C28H30N2O2Color and Shape:NeatMolecular weight:426.55N-Nitroso Aryl Lurasidone
CAS:Controlled ProductFormula:C11H12N4OSColor and Shape:NeatMolecular weight:248.31Trimebutine-d9 Maleate Salt
CAS:Controlled Product<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C22H20D9NO5·C4H4O4Color and Shape:NeatMolecular weight:512.62-Amino-5-benzoyl-1-methylbenzimidazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) thermal decomposition product. Mebendazole impurity.<br>References Himmelreich, M., et al.: Aus. J. Pharmaceut. Sci., 6, 123 (1977),<br></p>Formula:C15H13N3OColor and Shape:NeatMolecular weight:251.284-Hydroxy Triazolam
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications A metabolite of Triazolam (T767380).<br>References Gall, M., et al.: J. Med. Chem., 21, 1290 (1978), Jones, H., et al.: Drug Metab. Dispos., 32, 973 (2004), Hallifax, D., et al.: Drug Metab. Dispos., 33, 1852 (2005).<br></p>Formula:C17H12Cl2N4OColor and Shape:NeatMolecular weight:359.214'-Desmethoxy Omeprazole
CAS:Controlled Product<p>Applications 4'-Desmethoxy Omeprazole is one of two impurities in the synthesis of Esomeprazole, an anti-ulcerative drug for treatment of acid-related diseases.<br>References Liu, X., et al.: Lat. Am. J. Pharm., 34, 1265-1268 (2015);<br></p>Formula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.39Nitroguanidine (Wetted with water >20%)
CAS:Controlled Product<p>Applications Nitroguanidine is used in the prediction of heats of detonation of energetic compounds from their molecular structure. It is also used in the synthetic preparation of imidacloprid-d4 (I274992), which is a neonicotinoid.<br> E0<br>References Keshavarz, M.H., et al.: Propellant, Explosives, Pyrotechnics, 37, 93 (2012); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:CH4N4O2Color and Shape:White To Off-WhiteMolecular weight:104.072-Cyclopropylmethylamino-5-chlorobenzophenone
CAS:Controlled Product<p>Applications: 2-Cyclopropylmethylamino-5-chlorobenzophenone is a benzodiazepine derivative.<br>References Japp, M. et al.: J. Chrom., 439, 317 (1988); Guan, F. et al.: J. Anal Toxicol., 23, 54 (1999);<br></p>Formula:C17H16ClNOColor and Shape:NeatMolecular weight:285.772,5-Dichlorobenzoyl Cyanide
CAS:Controlled Product<p>Applications 2,5-Dichlorobenzoyl Cyanide is a reagent applied for research purposes<br>References Veerareddy, A., et al.: J. Heterocyclic Chem., 51, 1311 (2014)<br></p>Formula:C8H3Cl2NOColor and Shape:NeatMolecular weight:200.022Temazepam
CAS:Controlled Product<p>Applications Temazepam is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C16H13ClN2O2Color and Shape:Light YellowMolecular weight:300.74(2Z)-2-[Cyano(2,3-dichlorophenyl)methylene]hydrazinecarboximidamide
CAS:Controlled ProductFormula:C9H7Cl2N5Color and Shape:NeatMolecular weight:256.09Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity
CAS:Controlled Product<p>Applications Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C34H36Cl2N8O5Color and Shape:NeatMolecular weight:707.612,4-Dicyano-3-(2-methylpropyl)-pentanediamide (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygrscopic<br>Applications 2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.<br>References Hoekstra, M.S., et al.: Org. Proc. Rec. Deve., 1, 26 (1997); Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951); Gerlach, M., et al.: Brain Res., 741, 142 (1996); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C11H16N4O2Color and Shape:NeatMolecular weight:236.27Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Formula:C28H38N4O3SColor and Shape:NeatMolecular weight:510.69Propantheline-d3 Iodide
CAS:Controlled Product<p>Applications Labelled Propantheline (P760900). Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.<br>References Levin, R. et al.: Neurol. Urodyn., 1, 221 (1982); Daniotti, S. et al.: Br. J. Pharmacol., 82, 305 (1984); Moller, J. et al .: Acta Med. Scand., 184, 201 (1968);<br></p>Formula:C23H27D3INO3Color and Shape:NeatMolecular weight:498.41Benzofuran-6-carboxylic Acid
CAS:Controlled Product<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Formula:C9H6O3Color and Shape:NeatMolecular weight:162.142,5-Dichlorothiophen-3-yl Tioconazole Hydrochloride
CAS:Controlled ProductFormula:C16H12Cl4N2OS·ClHColor and Shape:NeatMolecular weight:458.62Metopimazine-d6
CAS:Controlled Product<p>Applications Labelled Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Formula:C22H21D6N3O3S2Color and Shape:NeatMolecular weight:451.642-Chloroacetamide
CAS:Controlled Product<p>Applications A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aptula, A., et al.: Chem. Res. Toxicol., 19, 1097 (2006), Chan, K., et al.: J. Appl. Toxicol., 28, 608 (2008),<br></p>Formula:C2H4ClNOColor and Shape:WhiteMolecular weight:93.51N-Desethyl N-Methyl Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C13H20N2O2Color and Shape:NeatMolecular weight:236.322-Chloromethyl-4-methoxy-3-methylpyridine Hydrochloride
CAS:Controlled Product<p>Applications A pyridine derivative used in the preparation of anti-ulcerative agents and other pharmaceutical compounds.<br>References Kuehler, T.C. et al.: J. Med. Chem., 38, 4906 (1995);<br></p>Formula:C8H10ClNO·ClHColor and Shape:NeatMolecular weight:208.08Lormetazepam
CAS:Controlled Product<p>Applications An analog of Lorazepam (L469850). Sedative, hypnotic.Controlled substance (depressant).<br>References Nudelman, A., et al.: J. Pharma. Sci., 63, 1886 (1974), Humpel, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 4, 237 (1979), Girkin, R., et al.: Xenobiotica, 10, 401 (1980),<br></p>Formula:C16H12Cl2N2O2Color and Shape:Light Yellow To Light GreenMolecular weight:335.18Scopolamine β-D-Glucuronide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Scopolamine.<br>References Shutt, L., et al.: Anaesthesia, 34, 476 (1979), Wada, S., et al.: Xenobiotica, 21, 1289 (1991), Chen, X., et al.: Acta Pharm. Sin., 33, 849(1998),<br></p>Formula:C23H29NO10Purity:>85%Color and Shape:NeatMolecular weight:479.4810-Acetyloxy Oxcarbazepine
CAS:Controlled Product<p>Applications An intermediate in the preparation of Carbamazepine metabolites.<br>References Heckendorn, R., et al.: Helv. Chimica Acta, 70, 1955 (1987),<br></p>Formula:C17H14N2O4Color and Shape:NeatMolecular weight:310.3010-Chloro Carbamazepine
CAS:<p>Applications 10-Chloro Carbamazepine is a derivative of Carbamazepine (C175840) which is used in treatment of pain associated with trigeminal neuralgia.<br>References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Formula:C15H11ClN2OColor and Shape:White PowderMolecular weight:270.71
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