Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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2-cyclopropyl-1H-benzimidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:158.20399475097656N-Methyl Pantoprazole(Mixture of 1 and 3 isomers)
CAS:<p>Impurity Pantoprazole EP Impurity D;<br>Applications N-Methyl Pantoprazole (Pantoprazole EP Impurity D) is an impurity of Omeprazole and Pantoprazole. Mixture of 1 and 3 isomers (mixture of impurity D and F).<br>References McClean, S., et al.: Anal. Chim. Acta, 292, 81 (1994), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997), Avgerinos, A., et al.: Eur. J. Drug Metab. Pharmacokinet., 23, 329 (1998), Wahbi, A., et al.: J. Pharm. Biomed. Anal., 30, 1133 (2002),<br></p>Formula:C17H17F2N3O4SColor and Shape:Light RedMolecular weight:397.405-Phenylthio-2-aminobenzimidazole
CAS:Controlled Product<p>Applications 5-Phenylthio-2-aminobenzimidazole, is a derivative of Fenbendazole (F246750), an anthelmintic.<br>References Baeder, C., et al.: Experientia, 30, 753 (1974), Van der Put, E., et al.: J. Immunol., 173, 818 (2004), Frasca, D., et al.: J. Immunol., 175, 6633 (2005),<br></p>Formula:C13H11N3SColor and Shape:Light Brown To OrangeMolecular weight:241.313-(1H-IMIDAZOL-2-YL)PROPANOIC ACID HCL
CAS:Formula:C6H9ClN2O2Purity:97%Color and Shape:SolidMolecular weight:176.65-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:329.42001342773444-Hydroxy Midazolam
CAS:Controlled Product<p>Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3OColor and Shape:Off-WhiteMolecular weight:341.771-Amino Hydantoin-13C3
CAS:<p>Applications 1-Amino Hydantoin Hydrochloride (A611090), a metabolite of Nitrofuran.Environmental contaminants<br>References Tribalat, L., et al.: Anal. Bioanal. Chem., 386, 2168 (2006), Chu, P., et al.: J. Agric. Food Chem., 55, 2129 (2007),<br></p>Formula:C3H5N3O2Color and Shape:White To Light YellowMolecular weight:118.07rac Dihydro Mebendazole
CAS:<p>Applications The reduced metabolite of Mebendazole (M200500).<br>References Facino, R., et al.: Biol. Mass Spectrom, 21, 195 (1992), Iosifidou, E., et al.: Drug Metab. Dispos., 25, 317 (1997), De Ruyck, H., et al.: J. Agric. Food Chem., 49, 610 ( 2001),<br></p>Formula:C16H15N3O3Color and Shape:Light YellowMolecular weight:297.31N-(3-(1H-imidazol-1-yl)propyl)-4-ethoxybenzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:302.39999389648446-O-Desmethyl Donepezil-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.<br>References De Vos, F., et al.: Nuc. Med. Biol., 27, 745 (2000), Okereke, C., et al.: Brit. J. Clin. Pharmacol., 58, 41 (2004),<br></p>Formula:C232H5H22NO3Color and Shape:NeatMolecular weight:370.50(1R)-(-)-10-Camphorsulfonic Acid
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity E (1R)-Isomer<br>Stability Hygroscopic<br>Applications (1R)-(-)-10-Camphorsulfonic Acid (Voriconazole EP Impurity E (1R)-Isomer) is a chiral derivative of Camphor. Used in the preparation of a chiral recognition polymer that is used in the chiral separation of amino acids. A catalyst in direct animation of α-branched aldehydes (including important biological molecules such as α-Me phenylglycine) with near perfect enantioselectivity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, H. et al.: Polym. Preprints Am. Chem. Soc., 40, 506 (1999); Liu, C. et al.: Org. Lett., 13, 2638 (2011);<br></p>Formula:C10H16O4SColor and Shape:WhiteMolecular weight:232.30(S)-Luliconazole
CAS:Controlled Product<p>Applications (S)-Luliconazole is the (S)--enantiomer of Luliconazole, an azole antifungal drug. Luliconazole was found to interfere with ergosterol biosynthesis in cell-free extracts of Candida albican, while no interference due to (S)-Luliconazole was found.<br>References Uhida, K., et al.: J. Infect. Chemother., 10, 216 (2004); Niwano, ., et al.: Antimicro. Agents Chemother., 42, 967 (1998); Niwanno, Y., et al.: Med. Mycol., 37, 351 (1999)<br></p>Formula:C14H9Cl2N3S2Color and Shape:NeatMolecular weight:354.28Isometronidazole
CAS:Controlled Product<p>Impurity Metronidazole EP Impurity E<br>Applications Isometronidazole (Metronidazole EP Impurity E) is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6H9N3O3Color and Shape:NeatMolecular weight:171.15(2-Imidazol-1-yl-ethyl)-methyl-amine
CAS:Formula:C6H11N3Purity:95.0%Color and Shape:SolidMolecular weight:125.1752-Phenyloxazole-5-carboxylic acid
CAS:Formula:C10H7NO3Purity:95%Color and Shape:SolidMolecular weight:189.172-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole
CAS:Controlled Product<p>Applications 2-Methyl-5-nitro-1-(2-oxiranylmethyl)-1H-imidazole is an impurity of Ornidazole (O688500) which has antifertility activity.<br>References Jones, A., et al.: Xenobiotica, 27, 711 (1997); Cooper, T., et al.: J. Andrology, 18, 431 (1997)<br></p>Formula:C7H9N3O3Color and Shape:NeatMolecular weight:183.168-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine
CAS:Controlled Product<p>Impurity MIdazolam EP Impurity B<br>Applications 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine is an isomer of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Walser, A., et al.: J. Org. Chem., 43, 936 (1978); Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3Color and Shape:NeatMolecular weight:325.773-Hydroxy-N-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-naphthamide
CAS:Purity:95.0%Molecular weight:319.32000732421875Hydroxy Metronidazole-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Formula:C62H4H5N3O4Color and Shape:Off-WhiteMolecular weight:191.182-((4,5-Diphenyloxazol-2-yl)thio)-N-isopropylacetamide
CAS:Purity:97.0%Molecular weight:352.450012207031252-(((6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,4-dimethoxypyridine 1-oxide
CAS:Purity:95.00%Molecular weight:399.36999511718753-Methoxybenzene-1,2-diamine
CAS:<p>Applications 3-Methoxybenzene-1,2-Diamine (cas# 37466-89-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C7H10N2OColor and Shape:BrownMolecular weight:138.175-(5-Fluoro-1-methyl-1h-1,3-benzodiazol-2-yl)-2-methylaniline
CAS:Purity:95%Molecular weight:255.296005249023442-METHOXY-5-(5-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PHENOL
CAS:Purity:95.0%Molecular weight:317.3479919433594Rufinamide-d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N4OColor and Shape:White To Light YellowMolecular weight:240.21Varenicline N-Glucoside
CAS:Controlled Product<p>Applications A metabolite of Varenicline. Metabolite M7.<br>References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005),<br></p>Formula:C19H23N3O5Color and Shape:NeatMolecular weight:373.40(4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methanol Hydrochloride
CAS:Controlled ProductFormula:C11H17NO3·HClColor and Shape:NeatMolecular weight:211.26 + 36.46(E)-2-(4-(1H-Imidazol-4-yl)styryl)-1H-indene-1,3(2H)-dione
CAS:Purity:95.0%Molecular weight:314.3439941406252-Phenyl-1H-benzoimidazol-5-ylamine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:209.2519989013672(R)-5-Hydroxymethyl Tolterodine
CAS:Controlled Product<p>Applications A metabolite of Tolterodine (T535800), a muscarinic receptor antagonist used in the treatment of urinary incontinence.<br>References Palmer, L., et al.: J. Pharm. Biomed. Anal., 16, 155 (1997), Hills, C., et al.: Drugs, 55, 813 (1998), Wefer, J., et al.: World J. Urol., 19, 312 (2001),<br></p>Formula:C22H31NO2Color and Shape:NeatMolecular weight:341.49Triclabendazole Sulfone
CAS:Controlled Product<p>Applications Triclabendazole Sulfone is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C14H9Cl3N2O3SColor and Shape:Off-WhiteMolecular weight:391.66Hydroxy Metronidazole
CAS:<p>Applications A metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Formula:C6H9N3O4Color and Shape:WhiteMolecular weight:187.152-[2-Cyclopropyl-5-fluoro-1H-benzo[d]imidazol-1-yl]acetic acid
CAS:Molecular weight:234.229995727539062-(2,3-Dichlorphenyl)-2-(guanidinylimino)acetonitrile
CAS:Controlled ProductFormula:C9H7Cl2N5Color and Shape:Light YellowMolecular weight:256.091-(2-naphthylmethyl)-1H-benzimidazole-2-carbaldehyde
CAS:Purity:95.0%Molecular weight:286.3340148925781(R)-Rabeprazole Sodium Salt
CAS:Controlled Product<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Formula:C18H20N3NaO3SColor and Shape:NeatMolecular weight:381.422,3,5-Trimethylpyridine N-Oxide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Formula:C8H11NOColor and Shape:Off-White To Light BrownMolecular weight:137.18ETHYL 1-CYCLOHEXYL-2-(FURAN-3-YL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXYLATE
CAS:Purity:95.0%Molecular weight:338.4070129394531Triclabendazole Sulfoxide
CAS:<p>Applications Triclabendazole Sulfoxide is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C14H9Cl3N2O2SColor and Shape:ColourlessMolecular weight:375.66Bis(4-cyanophenyl)methanol
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications A metabolite of Letrozole.<br>References Koyama, E., et al.: Ther. Drug Monit., 15, 224 (1993), Pfister, C., et al.: J. Pharm. Sci., 83, 520 (1994), Vander H.Y., et al.: J. Pharm. Biomed. Anal., 24, 723 (2001), Cohen, M., et al.: Clin. Cancer Res., 8, 665 (2002),<br></p>Formula:C15H10N2OColor and Shape:NeatMolecular weight:234.25
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