Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
At CymitQuimica, we offer high-purity benzimidazoles and imidazoles for research in medicinal chemistry, pharmacology, and biotechnology.
Found 10375 products of "Benzimidazole and Imidazole Derivatives"
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Varenicline N-Glucoside
CAS:Controlled Product<p>Applications A metabolite of Varenicline. Metabolite M7.<br>References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005),<br></p>Formula:C19H23N3O5Color and Shape:NeatMolecular weight:373.40Nimorazole
CAS:Controlled Product<p>Applications Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa.<br>References Ratnaparkhi, M.P., et al.: Res. J. Pharma. BIol. Chem. Sci., 3, 303 (2012); Toustrup, K., et al.: Radiotherap. Oncol., 102, 122 (2012);<br></p>Formula:C9H14N4O3Color and Shape:NeatMolecular weight:226.232-Nitroaniline
CAS:Controlled Product<p>Impurity Albendazole Impurity 4<br>Applications 2-Nitroaniline, is the main precursor to phenylenediamines, which are converted to benzimidazoles, a family of heterocycles that are key components in pharmaceuticals. Albendazole Impurity 4<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Booth, G.,et al.: Ull. Encyc. Indust. Chem. (2007);<br></p>Formula:C6H6N2O2Color and Shape:NeatMolecular weight:138.12Tinidazole-d5
CAS:Controlled Product<p>Applications Labelled Tinidazole. Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H8D5N3O4SColor and Shape:NeatMolecular weight:252.3Miconazole Impurity B
CAS:Controlled Product<p>Applications Miconazole Impurity B, is the impurity of Miconazole (M342500), which is an imidazole antifungal agent, that is applied topically to the skin or to mucus membranes for the treatment of fungal infections.<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H15Cl3N2OColor and Shape:NeatMolecular weight:381.68Carbamezepine-D10
CAS:Controlled Product<p>Applications Carbamazepine-D10 is used to study occurrence of emerging trace organic chemicals in wastewater effluents in Saudi Arabia.<br>References Alidina, M., et al.: Sci. Total Environ., 478, 152 (2014);<br></p>Formula:C152H10H2N2OColor and Shape:NeatMolecular weight:246.33Iminostilbene N-Carbonyl Chloride
CAS:<p>Impurity Carbamazepine EP Impurity F<br>Stability Hygroscopic, Moisture Sensitive<br>Applications Iminostilbene N-Carbonyl Chloride is an intermediate in the preparation of Carbamazepine (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Takayama, H., et al.: Bioorg. Med. Chem. Lett., 17, 4729 (2007),<br></p>Formula:C15H10ClNOColor and Shape:NeatMolecular weight:255.701-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
CAS:<p>Impurity Miconazole EP Impurity F<br>Applications 1-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole (Miconazole EP Impurity F) is an impurity of Miconazole (M342505), an antifungal (1,2) agent (topical).<br>References 1. Godefroi, E. et al.: J. Med. Chem. 1969 Sep;12(5):784-91.2. Brugmans, J. et al.: Arch Dermatol. 1970 Oct;102(4):428-32.<br></p>Formula:C18H14Cl4N2OColor and Shape:NeatMolecular weight:416.134-(4-Cyanobenzyl)-1,2,4-triazole
CAS:Controlled Product<p>Applications 4-(4-Cyanobenzyl)-1,2,4-triazole is an intermediate in the synthesis of Letrozole (L330100), an oral, non-steroidal, aromatase inhibitor generally used to treat breast cancer as a result of hormone response after surgery.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995),<br></p>Formula:C10H8N4Color and Shape:NeatMolecular weight:184.20Hydroxy Itraconazole-d8
CAS:Controlled Product<p>Applications An isotopically Labelled metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It is a COVID19-related research product.<br>References Saag, M., et al.: Antimicrob. Agents Chemother., 32, 1 (1988), Haria, M., et al.: Drugs, 51, 585 (1996), Kousoulos, C., et al.: Anal. Bioanal. Chem., 384,199 (2006),<br></p>Formula:C35D8H30Cl2N8O5Color and Shape:NeatMolecular weight:729.681-(TETRAHYDRO-2H-PYRAN-2-YL)-1H-INDAZOLE-6-CARBOXYLIC ACID
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:246.266006469726568-Chloro-6-(2-fluorophenyl)-3a,4-dihydro-1-methyl-3H-Imidazo[1,5-a][1,4]benzodiazepine (>90%)
CAS:Controlled ProductFormula:C18H15ClFN3Purity:>90%Color and Shape:Off-White To YellowMolecular weight:327.783-Dechloro-4-chloro Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity G<br>Applications 3-Dechloro-4-chloro Lamotrigine (Lamotrigine EP Impurity G) is a potential impurity of Lamotrigine (L173250).<br>References Rees, R., et al.: J. Med. Chem., 15, 859 (1972), McNamara, J., et al.: Nature, 399, A15 (1999),<br></p>Formula:C9H7Cl2N5Color and Shape:NeatMolecular weight:256.09(R)-Pregabalin
CAS:Controlled Product<p>Impurity Pregabalin USP Related Compound A<br>Applications R-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer). Pregabalin USP Related Compound A.<br>References Field, M.J. et al.: Br. J. Pharmacol., 132, 1 (2001); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993);<br></p>Formula:C8H17NO2Color and Shape:WhiteMolecular weight:159.23Tert-butyl(4s)-4-[(E)-3-bromoprop-1-enyl]-2,2-dimethyl-oxazolidine-3-carboxylate
CAS:Purity:97% mix TBC as stabilizerMolecular weight:320.22698974609375Ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
CAS:Purity:97.0%Molecular weight:468.190988628Lansoprazole N-Oxide
CAS:Controlled Product<p>Impurity Lansoprazole EP Impurity A<br>Applications Lansoprazole N-Oxide (Lansoprazole EP Impurity A) is an impurity of Lansoprazole (L175000) formed during the bulk synthesis of the drug.<br>References Kubo, K., et al.: Chem. Pharm. Bull., 38, 2853 (1990), Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006),<br></p>Formula:C16H14F3N3O3SColor and Shape:NeatMolecular weight:385.36N-(Benzyloxy)-5-methyl-2-phenyloxazole-4-carboxamide
CAS:Purity:98%Molecular weight:308.33700561523443-(1H-IMIDAZOL-2-YL)PROPANOIC ACID HCL
CAS:Formula:C6H9ClN2O2Purity:97%Color and Shape:SolidMolecular weight:176.65-(5-Fluoro-1-methyl-1h-1,3-benzodiazol-2-yl)-2-methylaniline
CAS:Purity:95%Molecular weight:255.29600524902344Lamotrigine 3,3-Dimer
CAS:Controlled Product<p>Applications Lamotrigine 3,3-Dimer is a dimer impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C19H14Cl4N10Color and Shape:NeatMolecular weight:524.195-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:329.42001342773441-(2-((4-Chlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
CAS:Purity:97.0%Color and Shape:Liquid, No data available.Molecular weight:381.67999267578125Voriconazole-d3
CAS:Controlled Product<p>Applications Labelled Vorizonazole (V760000), used as an antifungal (systemic). An Ergosterol Biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C162H3H11F3N5OColor and Shape:White To BeigeMolecular weight:352.335-Acetyl-10,11-dihydro-5H-dibenzo[b,f]azepine
CAS:Controlled Product<p>Impurity Carbamazepine Impurity 2<br>Applications 5-Acetyl-10,11-dihydro-5H-dibenzo[b,f]azepine, is Dibenz[b,f]azepine derivative, possessing antioxidant potentials. It is also an analogue of Imipramine (I465980), and Desipramine (D290050). Carbamazepine Impurity 2.<br>References Kumar, H. V., et al.: E- J. Chem., 5, 1123 (2008); Bhattacharjee, A. K., et al.: J. Chem. Info. Comp. Sci., 42 (2002);<br></p>Formula:C16H15NOColor and Shape:NeatMolecular weight:237.30(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
CAS:Controlled Product<p>Applications (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-Butanediol (cas# 133775-25-4) is a useful research chemical.<br></p>Formula:C12H13F2N3O2Color and Shape:NeatMolecular weight:269.258(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one (Mixture of Regioisomers)
CAS:Controlled Product<p>Impurity Omeprazole EP Impurity F+Omeprazole EP Impurity G<br>Stability Sample unstable under MS condition<br>Applications 8(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one(Mixture of Regioisomers) (Omeprazole EP Impurity F+Omeprazole EP Impurity G) is a mixture of regioisomers of Omeprazole Impurity.<br>References Rackur, G., et al.: Biochem. Biophys. Res. Commmun., 128, 477 (1985),<br></p>Formula:C16H13N3O2SColor and Shape:NeatMolecular weight:311.36(E)-2-((1-Acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity)
CAS:Purity:97%Color and Shape:SolidMolecular weight:428.514'-Ethoxyacetophenone
CAS:<p>Applications 4'-Ethoxyacetophenone, is an acetophenone derivative that can be used as an antibacterial agent. It is a reagent for plymerization. It can also be used as a flavoring agent in fabricating cigarettes with flavored filter tips.<br>References Sivakumar, P., et al.: Chem. Bio. Drug Design, 72, 303 (2008); Mathis, D. E., Beitraege zur Tabakforschung Int., 12, 1 (1983);<br></p>Formula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.20rac Rivastigmine-d6
CAS:Controlled Product<p>Applications Labelled rac Rivastigmine. A brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C14H16D6N2O2Color and Shape:NeatMolecular weight:256.37Atropine-N-oxide Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Atropine-N-oxide Hydrochloride is an alkaloid. A neuroprotective compound with potential therapeutic efficacy.<br>References Beraki, S., et al.: PLoS One, 8, 69233 (2013); Polonovski, M., et al: Compt. rend., 180, 1755 (1925)<br></p>Formula:C17H23NO4·ClHColor and Shape:NeatMolecular weight:341.83(S)-N-Desethyl Oxybutynin Hydrochloride
CAS:Controlled Product<p>Applications (S)-Metabolite of the drug Oxybutynin. Used in the treatmentment of incontinence.<br>References Ehlert, F., et al.: Life Sci., 74, 355 (2003), Matsui-Sakata, A., et al.: Drug Metab. Pharmacokinet., 20, 187 (2005), Hegde, S., et al.: Br. J. Pharmacol., 147, S80 (2006), Tashiro, M., et al.: Br. J. Clin. Pharmacol., 61, 16 (2006),<br></p>Formula:C20H27NO3·ClHColor and Shape:NeatMolecular weight:365.89N-(3-(1H-imidazol-1-yl)propyl)-4-ethoxybenzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:302.3999938964844Benzhydrol-d5
CAS:Controlled Product<p>Applications Intermediate in the preparation of labelled Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Formula:C13D5H7OColor and Shape:NeatMolecular weight:189.26(2-Oxopyrrolidin-1-yl)acetic Acid
CAS:<p>Impurity Piracetam Impurity D<br>Applications (2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors.<br>References Mitchell, C. J., et al.: Bioorg. Med. Chem. Lett., 20, 5803 (2010);<br></p>Formula:C6H9NO3Color and Shape:Off-WhiteMolecular weight:143.145-O-Desmethyl Omeprazole Sulfide
CAS:Controlled ProductFormula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.398-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine
CAS:Controlled Product<p>Impurity MIdazolam EP Impurity B<br>Applications 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine is an isomer of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Walser, A., et al.: J. Org. Chem., 43, 936 (1978); Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C18H13ClFN3Color and Shape:NeatMolecular weight:325.775-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-benzimidazol-2-one
CAS:<p>Applications 5-Chloro-6-(2,3-dichlorophenoxy)-1,3-dihydro-2H-benzimidazol-2-one is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C13H7Cl3N2O2Color and Shape:Off-White To BrownMolecular weight:329.571-Amino Hydantoin-13C3
CAS:<p>Applications 1-Amino Hydantoin Hydrochloride (A611090), a metabolite of Nitrofuran.Environmental contaminants<br>References Tribalat, L., et al.: Anal. Bioanal. Chem., 386, 2168 (2006), Chu, P., et al.: J. Agric. Food Chem., 55, 2129 (2007),<br></p>Formula:C3H5N3O2Color and Shape:White To Light YellowMolecular weight:118.07Hydroxy Voriconazole
Controlled Product<p>Applications A hydroxylated derivative of Voriconazole (V760000), a systemic antifungal and ergosterol biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997).<br></p>Formula:C16H14F3N5O2Color and Shape:NeatMolecular weight:365.31Rufinamide-d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N4OColor and Shape:White To Light YellowMolecular weight:240.211-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole
CAS:Purity:98%Molecular weight:284.1700134277344
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