Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10373 products of "Benzimidazole and Imidazole Derivatives"
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Albendazole Sulfone
CAS:<p>Impurity Albendazole EP Impurity C / Albendazole Sulfone<br>Applications A metabolite of Albendazole, an anthelmintic. Albendazole EP Impurity C<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol. Lett., 6, 2: 51 (1996)<br></p>Formula:C12H15N3O4SColor and Shape:BeigeMolecular weight:297.333-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid
CAS:Formula:C9H17NO3Color and Shape:NeatMolecular weight:187.24Ref: 10-F538136
1gTo inquire2gTo inquire5gTo inquire10gTo inquire100mgTo inquire250mgTo inquire500mgTo inquireModafinil
CAS:Controlled Product<p>Applications Modafinil is an a-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.This is a controlled substance (stimulant).<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219<br></p>Formula:C15H15NO2SColor and Shape:WhiteMolecular weight:273.35Carbamazepine 10,11-Epoxide
CAS:<p>Applications A metabolite of Carbamazepine (C175840).Representative lots contained 1-2% carbamazepine by HPLC.<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H12N2O2Purity:>97% by HPLCColor and Shape:NeatMolecular weight:252.27rac Rivastigmine-d6
CAS:Controlled Product<p>Applications Labelled rac Rivastigmine. A brain selective acetylcholinesterase inhibitor. Nootropic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formula:C14H16D6N2O2Color and Shape:NeatMolecular weight:256.376-Bromo-5-(2-fluoro-4-nitrophenoxy)-1-methyl-1H-indazole
CAS:Purity:95.0%Molecular weight:366.14599609375Oxcarbazepine-D4 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.Only available as a mixture of deuterated material:d-1: 1%d-2: 9%d-3: 35%d-4: 55%<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Formula:C152H4H8N2O2Color and Shape:Light Orange Colour PowderMolecular weight:256.29(R)-Rivastigmine
CAS:Controlled Product<p>Impurity Rivastigmine EP Impurity D<br>Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);<br></p>Formula:C14H22N2O2·C4H6O6Color and Shape:NeatMolecular weight:400.42Metronidazole-d4
CAS:Controlled Product<p>Applications Metronidazole-d4 is a labelled analog of Metronidazole (M338880). Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C62H4H5N3O3Color and Shape:Light YellowMolecular weight:175.184-(1H-Tetrazol-1-yl)aniline
CAS:Formula:C7H7N5Purity:95%Color and Shape:SolidMolecular weight:161.168((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone
CAS:Controlled Product<p>Impurity Solifenacin EP Impurity D<br>Applications ((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColor and Shape:NeatMolecular weight:444.57N-Ethyl-N-(4-picolyl)atropamide (>85%)
CAS:<p>Stability Light Sensitive<br>Applications N-Ethyl-N-(4-picolyl)atropamide is a major impurity of Tropicamide (T892650), a medication used to dilate the pupil.<br>References Stefanowicz, Zdzislawa, et al.: J. of Pharma. and Biomed. Analy., 49(2), 214-220 (2009)<br></p>Formula:C17H18N2OPurity:>85%Color and Shape:NeatMolecular weight:266.34(S)-Pregabalin-13C3
CAS:Controlled Product<p>Applications (S)-Pregabalin-13C3, is the labeled analogue of (S)-Pregabalin (P704790), a S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C513C3H17NO2Color and Shape:Off-WhiteMolecular weight:162.2Benzhydrol-d5
CAS:Controlled Product<p>Applications Intermediate in the preparation of labelled Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Formula:C13D5H7OColor and Shape:NeatMolecular weight:189.26(S)-N-Desethyl Oxybutynin Hydrochloride
CAS:Controlled Product<p>Applications (S)-Metabolite of the drug Oxybutynin. Used in the treatmentment of incontinence.<br>References Ehlert, F., et al.: Life Sci., 74, 355 (2003), Matsui-Sakata, A., et al.: Drug Metab. Pharmacokinet., 20, 187 (2005), Hegde, S., et al.: Br. J. Pharmacol., 147, S80 (2006), Tashiro, M., et al.: Br. J. Clin. Pharmacol., 61, 16 (2006),<br></p>Formula:C20H27NO3·ClHColor and Shape:NeatMolecular weight:365.89Mebendazole
CAS:Controlled Product<p>Applications Mebendazole is an Anthelmintic (Nematodes).<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 16, 291 (1987)<br></p>Formula:C16H13N3O3Color and Shape:NeatMolecular weight:295.292-Methoxy-4-nitroaniline
CAS:<p>Applications 2-Methoxy-4-nitroaniline is a derivative of 4-Nitroaniline (N491770), which is used in the synthesis of photorefractive polymers, as novel chromophores in analytical study. As well, due to the absorption spectrum associated with 4-Nitroaniline, it is used to determine catechol derivatives in syntheses.<br>References Nagaraja, P. et al.: J. Pharm. Biomed. Anal., 25, 417 (2001);<br></p>Formula:C7H8N2O3Color and Shape:YellowMolecular weight:168.153-Methoxy-temazepam
CAS:Controlled ProductFormula:C17H15ClN2O2Color and Shape:Off-White To Light YellowMolecular weight:314.77Triazolam
CAS:Controlled Product<p>Applications Sedative, hypnotic.Controlled substance (depressant).<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4Color and Shape:WhiteMolecular weight:343.21Triclabendazole Sulfoxide-D3
CAS:Controlled Product<p>Applications Triclabendazole Sulfoxide-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14H6D3Cl3N2O2SColor and Shape:NeatMolecular weight:378.682-Methyl-1-phenyl-1 H -benzoimidazole-5-carboxylic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:252.27299499511724-Methylenepiperidine Hydrochloride
CAS:Controlled Product<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>Formula:C6H11N•(HCl)Color and Shape:NeatMolecular weight:97.163646N-(tert-Butyl)-2-((4,5-diphenyloxazol-2-yl)thio)propanamide
CAS:Purity:97.0%Molecular weight:380.510009765625N-Nitroso Methyl Aniline Derivative
CAS:Formula:C14H11ClN2O2Color and Shape:WhiteMolecular weight:274.7023rac Desethyl Oxybutynin Hydrochloride
CAS:Controlled Product<p>Applications A metabolite of the drug Oxybutynin. Used in the treatment of incontinence.<br>References Hughes, K., et al.: Xenobiotica, 22, 859 (1992), Oki, T., et al.: Biol. Pharm. Bull., 24, 491 (2001), Fetscher, C., et al.: Br. J. Pharmacol., 136, 64 (2002), Zobrist, R., et al.: Pharm. Res., 20, 103 (2003)<br></p>Formula:C20H27NO3·ClHColor and Shape:BeigeMolecular weight:365.894-Nitro-1H-imidazole
CAS:Controlled Product<p>Applications Metronidazole (M338880) derivative, an antibacterial in the treatment of rosacea and inflammatory bowel disease.<br>References Khan, K. et al.; Am. J. Gastroenterol. 106, 661 (2011)<br></p>Formula:C3H3N3O2Color and Shape:NeatMolecular weight:113.07rac-Pregabalin
CAS:Controlled Product<p>Applications A GABA analogue used as an anticonvulsant.Controlled substance in the United States.Not controlled in Germany<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H17NO2Color and Shape:White SolidMolecular weight:159.23Atropic Acid
CAS:<p>Impurity Ipratropium EP Impurity D<br>Stability Light Sensitive<br>Applications Atropic acid (Ipratropium EP Impurity D) is an impurity of Ipratropium bromide (I740500) and Atropine Sulfate (A794625).<br>References Lyon, R., et al.: J. Pharm. Sci., 95, 1549 (2006), Loch, M., et al.: Toxicology, 233, 229 (2007), John, H., et al.: Anal. Bioanal. Chem., 396, 751 (2010),<br></p>Formula:C9H8O2Color and Shape:Off-WhiteMolecular weight:148.16Lamotrigine N2-Oxide
CAS:Controlled Product<p>Applications Lamotrigine analog for production of anti-lamotrigine antibodies and use as immunoassay reagent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Doig, M.V., et al.: J. Chromatogr., 554, 181 (1991),<br></p>Formula:C9H7Cl2N5OPurity:90%Color and Shape:NeatMolecular weight:272.092-Mercaptobenzimidazole
CAS:Controlled Product<p>Impurity Rabeprazole EP Impurity F<br>Applications An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole (R070500)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beheshti, A., et al.: J. Food Sci., 75, C135 (2010), Rohrig, U., et al.: J. Med. Chem., 53, 1172 (2010),<br></p>Formula:C7H6N2SColor and Shape:NeatMolecular weight:150.20Modafinil Sulfone
CAS:Controlled ProductFormula:C15H15NO3SColor and Shape:NeatMolecular weight:289.3495Secnidazole
CAS:Controlled Product<p>Applications Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H11N3O3Color and Shape:White To Light YellowMolecular weight:185.181-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
CAS:<p>Impurity Miconazole EP Impurity F<br>Applications 1-[2-(2,4-Dichlorophenyl)-2-[(3,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole (Miconazole EP Impurity F) is an impurity of Miconazole (M342505), an antifungal (1,2) agent (topical).<br>References 1. Godefroi, E. et al.: J. Med. Chem. 1969 Sep;12(5):784-91.2. Brugmans, J. et al.: Arch Dermatol. 1970 Oct;102(4):428-32.<br></p>Formula:C18H14Cl4N2OColor and Shape:NeatMolecular weight:416.1311-Keto Oxcarbazepine
CAS:Controlled Product<p>Stability Unstable in Solution<br>Applications A keto impurity of the anticonvulsant Oxcarbazepine (O869250).<br></p>Formula:C15H10N2O3Color and Shape:NeatMolecular weight:266.254-Isobutyl-2-pyrrolidinone (pregabalin lactam impurity)
CAS:<p>Impurity Pregabalin USP Related Compound C<br>Applications Pregabalin (P704800) intermediate. Pregabalin USP Related Compound C<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColor and Shape:Light YellowMolecular weight:141.21Voriconazole-d3
CAS:Controlled Product<p>Applications Labelled Vorizonazole (V760000), used as an antifungal (systemic). An Ergosterol Biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C162H3H11F3N5OColor and Shape:White To BeigeMolecular weight:352.33Iminostilbene
CAS:Controlled Product<p>Impurity Carbamazepine EP Impurity D<br>Applications A metabolite of Carbamazepine (CBZ) (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001),<br></p>Formula:C14H11NColor and Shape:Yellow To Dark OrangeMolecular weight:193.24Omeprazole Sulfone N-Oxide
CAS:<p>Impurity Omeprazole EP Impurity I<br>Applications Omeprazole Sulfone N-Oxide (Omeprazole EP Impurity I) is a metabolite of Omeprazole. Impurity I.<br>References Stevens, C.M., et al.: J. Biol. Chem., 75, 182 (1950), Okamoto, S., et al.: Biochem. Biophys. Res. Commun., 101, 440 (1981)<br></p>Formula:C17H19N3O5SColor and Shape:NeatMolecular weight:377.414'-Ethoxyacetophenone
CAS:<p>Applications 4'-Ethoxyacetophenone, is an acetophenone derivative that can be used as an antibacterial agent. It is a reagent for plymerization. It can also be used as a flavoring agent in fabricating cigarettes with flavored filter tips.<br>References Sivakumar, P., et al.: Chem. Bio. Drug Design, 72, 303 (2008); Mathis, D. E., Beitraege zur Tabakforschung Int., 12, 1 (1983);<br></p>Formula:C10H12O2Color and Shape:White To Off-WhiteMolecular weight:164.20Rivastigmine N-Oxide (Technical Grade)
CAS:Controlled Product<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Formula:C14H22N2O3Color and Shape:Light Yellow LiquidMolecular weight:266.34(2-Oxopyrrolidin-1-yl)acetic Acid
CAS:<p>Impurity Piracetam Impurity D<br>Applications (2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors.<br>References Mitchell, C. J., et al.: Bioorg. Med. Chem. Lett., 20, 5803 (2010);<br></p>Formula:C6H9NO3Color and Shape:Off-WhiteMolecular weight:143.14Metronidazole
CAS:<p>Applications Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.<br>References Carballo, M., et al.: J. App. Toxicol., 29, 248 (2009), Leitsch, D., et al.: Mol. Microbiol., 72, 518 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C6H9N3O3Color and Shape:White To Off-WhiteMolecular weight:171.15Atropine Sulfate Monohydrate
CAS:Controlled Product<p>Applications Mydriatic; antispasmodic; used in preanesthetic medication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),<br></p>Formula:C17H23NO3·H2O·H2O4SColor and Shape:White To Light YellowMolecular weight:694.83Fenbendazole Sulfoxide-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Fenbendazole (F246750).<br>References McKellar, Q., et al.: J. Vet. Pharmacol. Ther., 13, 223 (1990), De Ruyck, H., et al.: Food Control., 11, 165 (2000),<br></p>Formula:C152H3H10N3O3SColor and Shape:White To Off-WhiteMolecular weight:318.37Temazepam-13C,d3
CAS:Controlled Product<p>Applications Temazepam-13C,d3 is labelled Temazepam (T017200) which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Formula:C1513CH10D3ClN2O2Color and Shape:NeatMolecular weight:304.751-Methyl Mebendazole
CAS:Controlled Product<p>Impurity Mebendazole USP Related Compound D<br>Applications Mebendazole (M200500) related compound as anthelmintic agent. Mebendazole USP Related Compound D.<br>References Dhaneshwar, S.R., et al.: Indian Drugs, 28, 21 (1990),<br></p>Formula:C17H15N3O3Color and Shape:NeatMolecular weight:309.32
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