Benzimidazole and Imidazole Derivatives

<p>(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.</p>

<p>Amino albendazole sulfone is an anthelmintic drug that is used to treat worm infestations in animals. It is the active metabolite of fenbendazole sulfone and has a terminal half-life of 12 hours in humans. Amino albendazole sulfone can be prepared by chromatographic methods, such as liquid chromatography or gas chromatography, and it can be analyzed with a fluorescence detector. This drug has been shown to have a concentration–time curve following administration to rats and results in an increase in the number of worms eliminated from the body.</p>

<p>Lansoprazole impurity H is a metabolite of lansoprazole, a proton pump inhibitor that inhibits the production of stomach acid. Lansoprazole impurity H is used in research and development as an analytical standard to measure lansoprazole concentrations in drug products. It is also used as an impurity standard for pharmacopoeia purposes. Lansoprazole impurity H is not known to be toxic, but it has not been evaluated for carcinogenicity or reproductive toxicity.</p>

<p>Oxybutynin EP impurity B is a metabolite of oxybutynin and is a natural product. It is used as an analytical reference substance, to develop new drugs, and in pharmacopoeia in order to measure the purity of oxybutynin. The compound is synthesized by chemical synthesis and can be used as a standard for HPLC analysis.</p>

<p>Lactose conjugate degradation product of pregabalin</p>

<p>Dehydrodeoxy donepezil is an analytical standard that is used in the manufacture of pharmaceuticals. It is a synthetic drug impurity, and its CAS number is 120013-45-8. Dehydrodeoxy donepezil can be found in the API impurity grade of various drugs, including those that are manufactured by Custom synthesis and natural synthesis. The pharmacopoeia states that dehydrodeoxy donepezil has a purity level of 98% or greater. This product can also be found as a metabolite in humans, with its half-life being approximately 40 minutes.</p>

<p>2-Hydroxy-5-methylphenylbenzenepropanol is an aliphatic phenol that is used as a treatment for benzene poisoning. It is also used as a precursor to other compounds, such as the chlorides and alkylates of 2-hydroxy-5-methylphenylbenzenepropanol. This compound can be synthesized by reacting ethyl benzoylacetate with diisopropylamine in the presence of oxygen and chlorine gas. It is often immobilized using nutrients, l-tartaric acid, or cinnamic acid.</p>

<p>Oxybutynin impurity C is a metabolite of the drug product Oxybutynin (CAS No. 1199574-70-3). It is an analytical standard for HPLC, and a natural impurity in the synthesis of Oxybutynin. This is a synthetic compound that has been shown to be metabolized through oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Oxybutynin impurity C has been used as an analytical reference material for drug development and research and development.</p>

<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>

<p>Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.</p>

<p>Lactose conjugate degradation product of pregabalin</p>

<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.</p>

<p>6-Methyl-4-phenyl-3,4-dihydro-1-benzopyran-2-one is an analog of the natural product zearalenone, which can be used as an acid catalyst for the synthesis of various pharmaceuticals. It has a linear range and is structurally similar to a number of other analogs. The chloride ion is involved in the optimization of the extraction parameters and can be replaced by other c1-4 alkyl groups. 6-Methyl-4-phenyl-3,4-dihydro-1 -benzopyran 2 one is typically prepared using a preparative high performance liquid chromatography technique that involves dehydration.</p>

<p>1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is a synthetic compound which has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. This drug is racemized in the body and has been found to be effective against Parkinson's disease in rats. It is also an enantiomer that has industrial applications for the production of polyurethane foam insulation coatings.</p>

<p>4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol is a synthetic impurity standard that is used in the synthesis of drug products. This compound is also known as 4-methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol and has a CAS number of 480432-14-2. It is used to verify the purity of drugs and drug products. 4MMPP can be found in pharmacopoeia, drug development, and metabolite studies. This compound is a research and development product for niche markets. 4MMPP can be obtained through custom synthesis or by synthesis.</p>

<p>The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (</p>

<p>1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[(4-(3-methoxypropoxy)-3-methyl-2-pyridinyl)methylsulfonyl]-1H-benzimidazole (MKC1807) is a synthetic drug product. MKC1807 is an analytical standard in the HPLC assay for the determination of Epiandrosterone sulfate and its metabolites. 1-[4-(3-Methoxypropoxy)-3,5,6,7,8 -pentamethylcyclohexyl]methyl 2-[(4-(3 -methoxypropoxy) 3,5,6,7,8 -pentamethylcyclohexyl)methylsulfonyl]-1H benzimidazole has been shown to be a natural metabolite of Epiandrosterone sulfate. This compound</p>

<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>

<p>2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid is a synthetic compound that is being researched as a potential drug product. It is an impurity standard for HPLC and has been used in the past to develop drugs. The chemical structure of this compound closely resembles that of the natural metabolite 4,5-dimethoxybenzoic acid, which is found in plants such as thyme. 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic acid has shown to inhibit human cytochrome P450 enzymes, which may lead to serious side effects when taken orally.</p>

<p>2-[(4-Chloro-3-methyl-2-pyridinyl)methylthio]-1H-benzimidazole is a drug product. It is an impurity standard for the analytical determination of 2-[(4-chloro-3-methylpyridin)-2yl]thiohydantoin in pharmaceuticals and other chemical products. This compound is also used as a research and development (R&amp;D) metabolite and impurity standard for the synthesis of 4-(4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)pyridine. The CAS number for this compound is 103312-62-5./END&gt;</p>